Microglia in the neurohypophysis associate with and endocytose terminal portions of neurosecretory neurons.

abstract：:Recent studies suggest that neurons containing adrenocorticotropin and catecholamines are localized to similar areas of the brain. In this immunocytochemical study, the distributions of neurons and terminals containing adrenocorticotropin and tyrosine hydroxylase, the first enzyme in the catecholamine biosynthetic pat...

journal_title：Neuroscience

authors： Baker H,Ruggiero DA,Alden S,Anwar M,Reis DJ

更新日期：1986-02-01 00:00:00

abstract：:Hindbrain dorsal vagal complex A2 noradrenergic signaling represses the pre-ovulatory luteinizing hormone (LH) surge in response to energy deficiency. Insulin-induced hypoglycemia augments A2 neuron adenosine 5'-monophosphate-activated protein kinase (AMPK) activity and estrogen receptor-beta (ERβ) expression, coincid...

journal_title：Neuroscience

authors： Briski KP,Shrestha PK

更新日期：2016-09-07 00:00:00

abstract：:Two radial maze tasks, random foraging and delayed spatial win-shift, have been used to investigate, in rats, the functions and inter-relationships of structures connected through the corticostriatal loops, such as the prelimbic cortex, nucleus accumbens, ventral pallidum and mediodorsal thalamus. The random foraging ...

journal_title：Neuroscience

authors： Keating GL,Winn P

更新日期：2002-01-01 00:00:00

abstract：:Antisera raised against protein-glutaraldehyde-amino acid conjugates were used to study the light and electron microscopic distribution of GABA, glutamate, glutamine and taurine in organotypic slice cultures of rat hippocampi. In the stratum oriens and radiatum, glutamate-like immunoreactivity was particularly concent...

journal_title：Neuroscience

authors： Torp R,Haug FM,Tønder N,Zimmer J,Ottersen OP

更新日期：1992-01-01 00:00:00

abstract：:Activation of poly (ADP-ribose) polymerases (PARP) contributes to ischemic damage by causing neuronal nicotinamide adenine dinucleotide (NAD(+)) depletion, release of apoptosis-inducing factor and consequent caspase-independent cell death. PARP-mediated cell death is sexually dimorphic, participating in ischemic damag...

journal_title：Neuroscience

authors： Vagnerova K,Liu K,Ardeshiri A,Cheng J,Murphy SJ,Hurn PD,Herson PS

更新日期：2010-03-17 00:00:00

abstract：:Multiple aspartate-specific cysteine proteases have been identified and specific members of this family have been implicated in the apoptotic death of many mammalian cell types. Caspase-3-like proteases seem to play a pivotal role in neuronal apoptosis since mice with germline inactivation of the caspase-3 gene manife...

journal_title：Neuroscience

authors： Dodel RC,Du Y,Bales KR,Ling ZD,Carvey PM,Paul SM

更新日期：1998-10-01 00:00:00

abstract：:Previous studies have suggested that peptides such as substance P and thyrotropin-releasing hormone coexist with serotonin in the same varicosities in the ventral horn and intermediate gray of the spinal cord in rat. However, coexistence of these peptides with serotonin is rare in fibers in the superficial dorsal horn...

journal_title：Neuroscience

authors： Wu W,Wessendorf MW

更新日期：1992-10-01 00:00:00

abstract：:A recent study has described synchronous burst discharges of dentate hilar neurons and area CA3 pyramidal cells in the presence of the convulsants 4-aminopyridine and picrotoxin in guinea-pig hippocampal slices [Müller W. and Misgeld U. (1991) J. Neurophysiol. 65, 141-147]. To examine the synchronous activity of denta...

journal_title：Neuroscience

authors： Scharfman HE

更新日期：1994-03-01 00:00:00

abstract：:We tested a hypothesis that the classical relation between movement time and index of difficulty (ID) in quick pointing action (Fitts' Law) reflects processes at the level of motor planning. Healthy subjects stood on a force platform and performed quick and accurate hand movements into targets of different size locate...

journal_title：Neuroscience

authors： Bertucco M,Cesari P,Latash ML

更新日期：2013-02-12 00:00:00

abstract：:Brain injury-derived neurotrophic peptide is a 13-amino acid peptide derived from a 15,000 mol. wt neurotrophic factor released from sites of mechanical injury in neonatal rat brain. This peptide promotes survival of septal cholinergic neurons and mesencephalic dopaminergic neurons, and protects hippocampal neurons fr...

journal_title：Neuroscience

authors： Hama T,Maruyama M

更新日期：2000-01-01 00:00:00

abstract：:Obesity may result from dysfunction of the reward system, especially in the nucleus accumbens (Acb). Based on this hypothesis, many researchers have tested the effect of high-frequency stimulation (HFS) of the Acb shell (Acb-Sh) and/or core (Acb-Co) on ingestive behaviors, but few studies have explored the possible me...

journal_title：Neuroscience

authors： Wei N,Wang Y,Wang X,He Z,Zhang M,Zhang X,Pan Y,Zhang J,Qin Z,Zhang K

更新日期：2015-08-20 00:00:00

abstract：:Identification of novel molecules that can induce neuronal differentiation of embryonic stem (ES) cells is essential for deciphering the molecular mechanisms of early development and for exploring cell therapy approaches. Pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal polypeptide ...

journal_title：Neuroscience

authors： Chafai M,Basille M,Galas L,Rostene W,Gressens P,Vaudry H,Gonzalez BJ,Louiset E

更新日期：2011-12-29 00:00:00

abstract：:Iron may catalyse the production of reactive oxygen species during post-ischemic reoxygenation and subsequently lead to brain damage. Ferritin, an iron sequestering and storage protein, can also be a source of iron after ischemic insult. However, its role in ischemia-reperfusion has not been carefully investigated. In...

journal_title：Neuroscience

authors： Chi SI,Wang CK,Chen JJ,Chau LY,Lin TN

更新日期：2000-01-01 00:00:00

abstract：:Activation of microglia is regulated by controlling both its population size (through modulation of proliferation/death) and the production of inflammatory mediators. Retinoids control cellular proliferation, differentiation, and death. Natural retinoids have been shown to exhibit anti-inflammatory actions against act...

journal_title：Neuroscience

authors： Farso MC,Krantic S,Rubio M,Sarfati M,Quirion R

更新日期：2011-09-29 00:00:00

abstract：:Half of the cholinergic neurons of human and primate intrinsic cardiac ganglia (ICG) have a dual cholinergic/noradrenergic phenotype. Likewise, a large subpopulation of cholinergic neurons of the mouse heart expresses enzymes needed for synthesis of norepinephrine (NE), but they lack the vesicular monoamine transporte...

journal_title：Neuroscience

authors： Hoard JL,Hoover DB,Mabe AM,Blakely RD,Feng N,Paolocci N

更新日期：2008-09-22 00:00:00

abstract：:When the neural tracer Fluoro-Gold is used to retrogradely label a population of axotomized neurons, cellular labeling can persist in the axotomized nucleus even when Nissl staining indicates that the injured neurons have degenerated. In order to determine the identity of the labeled cells that remain, this study comb...

journal_title：Neuroscience

authors： Rinaman L,Milligan CE,Levitt P

更新日期：1991-01-01 00:00:00

abstract：:We revealed the structural features of astrocytes by means of light microscopy, confocal laser scanning microscopy and high voltage electron microscopy, and estimated their numerical densities in the mouse hippocampus. The high voltage electron microscope examinations of Golgi-impregnated astrocytes clearly disclosed ...

journal_title：Neuroscience

authors： Ogata K,Kosaka T

更新日期：2002-01-01 00:00:00

abstract：:The nucleotide oligomerization domain (NOD)-like receptor (NLR) pyrin domain-containing protein 1 (NLRP1) inflammasome has been shown to contribute to brain injury after ischemic stroke. Our previous study showed that microRNA-9a-5p (miR-9a-5p) ameliorates ischemic injury by regulating neuronal autophagy in rats subje...

journal_title：Neuroscience

authors： Cao Y,Zhang H,Lu X,Wang J,Zhang X,Sun S,Bao Z,Tian W,Ning S,Wang L,Cui L

更新日期：2020-09-15 00:00:00

abstract：:Overexpression of vascular endothelial growth factor (VEGF) is considered the most critical factor in radiation-induced brain injury (RBI). To investigate the role of VEGF and the mechanism underlying microvascular damage in RBI, wild type mice, and transgenic mice overexpressing VEGF derived from astrocytes, were sep...

journal_title：Neuroscience

authors： Zhou D,Huang X,Xie Y,Deng Z,Guo J,Huang H

更新日期：2019-06-01 00:00:00

abstract：:Whole-cell voltage-clamp recordings were made from acutely dissociated neurons obtained from the embryonic chick ciliary ganglion. Recording pipettes were filled with salines containing 120 mM CsCl or 120 mM tetraethylammonium-Cl. Application of depolarizing voltage commands evoked L-type Ca2+ currents and, at voltage...

journal_title：Neuroscience

authors： Dryer SE,Dourado MM,Wisgirda ME

更新日期：1991-01-01 00:00:00

abstract：:Recent studies investigating neural correlates of human thirst have identified various subcortical and telencephalic brain areas. The experience of thirst represents a homeostatic emotion and a state that slowly evolves over time. Therefore, the present study aims at systematically examining cerebral perfusion during ...

journal_title：Neuroscience

authors： Meier L,Federspiel A,Jann K,Wiest R,Strik W,Dierks T

更新日期：2018-07-15 00:00:00

abstract：:In the previous study, we observed chronological alterations of glutamic acid decarboxylase (GAD), which is the enzyme converting glutamate into GABA. GAD isoforms (GAD65 and GAD67) differ substantially in their interactions with cofactor pyridoxal 5'-phosphate, which is catalyzed by pyridoxal kinase (PLK). In the pre...

journal_title：Neuroscience

authors： Hwang IK,Yoo KY,Kim DS,Eum WS,Park JK,Park J,Kwon OS,Kang TC,Choi SY,Won MH

更新日期：2004-01-01 00:00:00

abstract：:Several isoforms of integrin subunits are expressed in Schwann cells and mediate Schwann cell interactions with axons. Here, we identify α6 and β1 integrins as heterodimeric proteins expressed in Schwann cells and define their functions in axonal regeneration. α6 and β1 integrins are induced in Schwann cells in the sc...

journal_title：Neuroscience

authors： Chang IA,Kim KJ,Namgung U

更新日期：2018-02-10 00:00:00

abstract：:Tolerance to the analgesic effects of morphine results in part from the development of a compensatory response in neurons that express the opioid receptor or of neural circuits in which those neurons participate. According to this formulation, withdrawal of morphine results in an overshoot of several neuronal properti...

journal_title：Neuroscience

authors： Rohde DS,Detweiler DJ,Basbaum AI

更新日期：1996-05-01 00:00:00

abstract：:This study shows that in adult rat spinal motoneurons brain-derived neurotrophic factor exerts a neuroprotective effect which extends several weeks beyond the duration of treatment. In addition, brain-derived neurotrophic factor strongly enhances regeneration of avulsed motor axons across the border between the centra...

journal_title：Neuroscience

authors： Novikov L,Novikova L,Kellerth JO

更新日期：1997-08-01 00:00:00

abstract：:In vitro receptor autoradiography was used to localize, quantify and characterize [125I-Tyr8]bradykinin binding sites in all major spinal cord segments of normal rats and animals subjected to various chemical treatments and surgical lesions. [125I-Tyr8]bradykinin specific binding sites were predominantly located to su...

journal_title：Neuroscience

authors： Lopes P,Kar S,Chrétien L,Regoli D,Quirion R,Couture R

更新日期：1995-10-01 00:00:00

abstract：:Neuronal differentiation is a critical developmental process that determines accurate synaptic connection and circuit wiring. A wide variety of naturally occurring compounds have been shown as promising drug leads for the generation and differentiation of neurons. Here we report that a diarylheptanoid from the plant A...

journal_title：Neuroscience

authors： Tang G,Dong X,Huang X,Huang XJ,Liu H,Wang Y,Ye WC,Shi L

更新日期：2015-09-10 00:00:00

abstract：:A satisfactory management to ensure a full restoration of peripheral nerve after trauma is not yet available. Using an experimental protocol, in which crush injury was applied 1 cm above the bifurcation of the rat sciatic nerve for 20 s, we here demonstrate that the levels of neuroactive steroids, such as pregnenolone...

journal_title：Neuroscience

authors： Roglio I,Bianchi R,Gotti S,Scurati S,Giatti S,Pesaresi M,Caruso D,Panzica GC,Melcangi RC

更新日期：2008-08-26 00:00:00

abstract：:Intrauterine growth restriction is a risk factor for neurological and behavioural deficits in children although the precise underlying biological correlate for this is unclear. The present study shows that animals with intrauterine growth restriction, induced by a period of reduced placental blood flow during the seco...

journal_title：Neuroscience

authors： Mallard C,Loeliger M,Copolov D,Rees S

更新日期：2000-01-01 00:00:00

abstract：:The lurcher mutation induces Purkinje cell degeneration in heterozygous mice, and neonatal death in homozygous animals. Using the D6Mit16 Simple Sequence Length Polymorphic marker in F2 hybrids between AKR +/+ mice and B6+/Lc mice, homozygous lurcher fetuses and newborns as well as heterozygous and normal littermates ...

journal_title：Neuroscience

authors： Resibois A,Cuvelier L,Goffinet AM

更新日期：1997-09-01 00:00:00