Clinico-pathological subtypes of hippocampal sclerosis in temporal lobe epilepsy and their differential impact on memory impairment.

abstract：:Neurotrophic factors are known to promote neuronal survival during development and after acute brain injury. Recent data suggest that some neuropeptides also exhibit neurotrophic activities, as shown for the pituitary adenylate cyclase activating polypeptide, which increases the survival of various neuronal population...

journal_title：Neuroscience

authors： Skoglösa Y,Lewén A,Takei N,Hillered L,Lindholm D

更新日期：1999-04-01 00:00:00

abstract：:Prior research with a rat model of behavioral therapy [i.e., effort-based reward (EBR) contingency training] suggests that strengthened associations between physical effort and desired outcomes enhance neurobiological indices of resilience. In the current study, male and female Long-Evans rats were exposed to either s...

journal_title：Neuroscience

authors： Kent M,Scott S,Lambert S,Kirk E,Terhune-Cotter B,Thompson B,Neal S,Dozier B,Bardi M,Lambert K

更新日期：2018-08-21 00:00:00

abstract：:Exposure of mice to the anesthetic gas nitrous oxide (N(2)O) produces a marked antinociceptive effect. Protein kinase C is a key regulatory enzyme that may be targeted by general anesthetics. However, a relationship between N(2)O-induced antinociception and protein kinase C has yet to be established. The present study...

journal_title：Neuroscience

authors： Ishikawa M,Matsushita Y,Abe K,Utsunomiya I,Hoshi K,Quock RM,Taguchi K

更新日期：2006-06-19 00:00:00

abstract：:We investigated the effects of intracerebroventricular injection of angiotensin II on neuronal immediate early gene-encoded protein synthesis in the brain of conscious rats. The expression of seven immediate early gene-encoded transcription factors (c-Fos, FosB, c-Jun, JunB, JunD, Krox-20 (Egr-2) and Krox-24 (NGFI-A, ...

journal_title：Neuroscience

authors： Lebrun CJ,Blume A,Herdegen T,Seifert K,Bravo R,Unger T

更新日期：1995-03-01 00:00:00

abstract：:Dominant and subordinate males respond differently to the stress of social interaction. After an hour of social interaction, subordinate male Anolis carolinensis have elevated serotonergic activity in hippocampus, but dominant males do not. In other species, and using other stressors, the activation of hippocampal ser...

journal_title：Neuroscience

authors： Summers CH,Summers TR,Moore MC,Korzan WJ,Woodley SK,Ronan PJ,Höglund E,Watt MJ,Greenberg N

更新日期：2003-01-01 00:00:00

abstract：:GABAA-receptors in the brain display a striking structural heterogeneity, which is based on a multiplicity of diverse subunits. The allocation of GABAA-receptor subtypes to identified neurons is essential for an analysis of the functional significance of receptor heterogeneity. Among GABA-receptive neurons, well-chara...

journal_title：Neuroscience

authors： Gao B,Fritschy JM,Benke D,Mohler H

更新日期：1993-06-01 00:00:00

abstract：:One week after injection of L-[35S]methionine into the dorsal motor nuclei of the guinea-pig, labelled tubulin carried down the vagal nerve by the slow phase of axonal transport was analysed by one- and two-dimensional gel electrophoresis. Transported tubulin showed a much stronger labelling of the beta-subunit. Isoel...

journal_title：Neuroscience

authors： Tashiro T,Komiya Y

更新日期：1983-08-01 00:00:00

abstract：:Transplantation of embryonic dopaminergic neurons is an experimental therapy for Parkinson's disease, but limited tissue availability and suboptimal survival of grafted dopaminergic neurons impede more widespread clinical application. Glial cell line-derived neurotrophic factor (GDNF) and neurotrophin-4/5 (NT-4/5) exe...

journal_title：Neuroscience

authors： Meyer M,Matarredona ER,Seiler RW,Zimmer J,Widmer HR

更新日期：2001-01-01 00:00:00

abstract：:Examination of spontaneous miniature endplate potentials (MEPPs) in murine skeletal muscle has revealed that in conditions such as botulinum poisoning, during nerve terminal regeneration or in the presence of the drug 4-aminoquinoline, two types of acetylcholine release are responsible for the MEPPs. In addition to th...

journal_title：Neuroscience

authors： Thesleff S,Molgó J

更新日期：1983-05-01 00:00:00

abstract：:The identification and characterization of excitatory and inhibitory neurons are significant steps in understanding neural network functions. In this study, we investigated the intrinsic electrophysiological properties of neurons in the prepositus hypoglossi nucleus (PHN), a brainstem structure that is involved in gaz...

journal_title：Neuroscience

authors： Shino M,Kaneko R,Yanagawa Y,Kawaguchi Y,Saito Y

更新日期：2011-12-01 00:00:00

abstract：:Approximately 50% of patients who survived after aneurysmal subarachnoid hemorrhage (SAH) have cognitive or neurobehavioral dysfunction. The mechanisms are not known. NR2B, one of the subunits of N-methyl-d-aspartate (NMDA) receptors, has been proved to be an important factor for synapse function and behavior cognitio...

journal_title：Neuroscience

authors： Chen G,Li Q,Feng D,Hu T,Fang Q,Wang Z

更新日期：2013-02-12 00:00:00

abstract：:Glutamate, the main excitatory amino acid transmitter in the vertebrate brain is involved in the dynamic changes in protein repertoire that underlie synaptic plasticity. Activity-dependent differential expression patterns occur not only in neurons but also in glial cells. In fact, a membrane to nuclei signaling has be...

journal_title：Neuroscience

authors： González-Mejia ME,Morales M,Hernández-Kelly LC,Zepeda RC,Bernabé A,Ortega A

更新日期：2006-09-01 00:00:00

abstract：:Neural activity during early development is known to alter innervation pathways in the central and peripheral nervous systems. We sought to examine how reduced sound-induced sensory activity in the cochlea affected the consolidation of glutamatergic synapses between inner hair cells (IHC) and the primary auditory neur...

journal_title：Neuroscience

authors： Barclay M,Constable R,James NR,Thorne PR,Montgomery JM

更新日期：2016-06-14 00:00:00

abstract：:The C57BL/Wld s mouse is a mutant strain of mouse that shows greatly slowed Wallerian degeneration both in the central and peripheral nervous system. Using immunohistochemistry, immunofluorescence and Western blotting, we have investigated the distribution of the chimeric Wld s protein and its different components in ...

journal_title：Neuroscience

authors： Fang C,Bernardes-Silva M,Coleman MP,Perry VH

更新日期：2005-01-01 00:00:00

abstract：:It was investigated whether grafts of the suprachiasmatic nucleus could re-instate circadian rhythmicity in the absence of its endogenous vasopressin production and whether the restored rhythm would have the long period length of the donor. Grafts of 17-days-old vasopressin-deficient homozygous Brattleboro rat fetuses...

journal_title：Neuroscience

authors： Boer GJ,van Esseveldt KE,van der Geest BA,Duindam H,Rietveld WJ

更新日期：1999-03-01 00:00:00

abstract：:The nucleus retroambiguus in the cat has been shown to receive strong projections from the periaqueductal gray and to send fibres to distinct motoneuronal cell groups in brainstem and spinal cord. The nucleus retroambiguus plays a role in the production of vocalization and possibly copulatory (lordosis and mounting) b...

journal_title：Neuroscience

authors： Holstege G,Kerstens L,Moes MC,Vanderhorst VG

更新日期：1997-09-01 00:00:00

abstract：:Semaphorins comprise a family of proteins involved in axon guidance during development. Semaphorin4D (Sema4D) has both neuroregenerative and neurorepressive functions, being able to stimulate both axonal outgrowth and growth cone collapse during development, and therefore could play an important role in neurological r...

journal_title：Neuroscience

authors： Peng SX,Yao L,Cui C,Zhao HD,Liu CJ,Li YH,Wang LF,Huang SB,Shen YQ

更新日期：2017-05-20 00:00:00

abstract：:Chronic restraint stress has been associated with induction of morphological changes in the hippocampus. Postsynaptically, these changes include decreased length and branching of apical dendrites from CA3 pyramidal neurons, while presynaptically, depletion and clustering of synaptic vesicles have been observed. Howeve...

journal_title：Neuroscience

authors： Gao Y,Bezchlibnyk YB,Sun X,Wang JF,McEwen BS,Young LT

更新日期：2006-09-01 00:00:00

abstract：:The distribution, structural organization and state of phosphorylation of neurofilaments have been examined in chromaffin cells from adult bovine adrenal medulla cultured under various conditions using a series of monoclonal antibodies directed against phosphorylated and nonphosphorylated epitopes of the 200,000 mol. ...

journal_title：Neuroscience

authors： Grant NJ,Demeneix B,Aunis D,Langley OK

更新日期：1988-11-01 00:00:00

abstract：:Previous findings, mainly in in vitro systems, have shown that the density of vesicles and the synaptic efficacy at excitatory synapses are reduced in the absence of synapsins, despite the fact that transgenic mice lacking synapsins develop an epileptic phenotype. Here we study glutamate receptors by quantitative immu...

journal_title：Neuroscience

authors： Gylterud Owe S,Bogen IL,Walaas SI,Storm-Mathisen J,Bergersen LH

更新日期：2005-01-01 00:00:00

abstract：:The primary somatosensory cortex (S1) projects to the thalamus and brainstem somatosensory nuclei and modulates somatosensory information ascending to the S1 itself. However, the projections from the S1 to the brainstem second-order somatosensory neuron pools have not been fully studied. To address this in rats, we fi...

journal_title：Neuroscience

authors： Tomita A,Kato T,Sato F,Haque T,Oka A,Yamamoto M,Ono T,Bae YC,Maeda Y,Sessle BJ,Yoshida A

更新日期：2012-01-03 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive neurodegenerative disorder, with no effective method for its treatment so far. The pathogenesis of AD has been reported, but the endogenous metabolic profile and disease-related biomarkers are still not clear. To better understand AD, an AD model induced by injecting β-amyloid...

journal_title：Neuroscience

authors： Liu Y,Wei M,Yue K,Hu M,Li S,Men L,Pi Z,Liu Z,Liu Z

更新日期：2018-12-01 00:00:00

abstract：:The laminar binding distribution of three nicotinic receptor agonists, [3H](-)nicotine, [3H]cytisine, and [3H]epibatidine, and their relation to the [3H]vesamicol binding, which is known to represent the vesicular acetylcholine transport sites, was performed employing in vitro autoradiography on the medial temporal co...

journal_title：Neuroscience

authors： Sihver W,Gillberg PG,Svensson AL,Nordberg A

更新日期：1999-01-01 00:00:00

abstract：:Inhibitory serotonergic and cholecystokinergic mechanisms in the lateral parabrachial nucleus and central GABAergic mechanisms are involved in the regulation of water and NaCl intake. In the present study we investigated if the GABA(A) receptors in the lateral parabrachial nucleus are involved in the control of water,...

journal_title：Neuroscience

authors： Callera JC,Oliveira LB,Barbosa SP,Colombari DS,De Luca LA Jr,Menani JV

更新日期：2005-01-01 00:00:00

abstract：:In the enteric nervous system, acetylcholine is the most common neurotransmitter to induce gastrointestinal smooth muscle contractions. Cholinergic signaling is mediated by muscarinic acetylcholine receptors on the surface of smooth muscle cells. Five different muscarinic receptor subtypes (M(1)-M(5)) have been identi...

journal_title：Neuroscience

authors： Iino S,Nojyo Y

更新日期：2006-01-01 00:00:00

abstract：:The pharmacological features of putative nicotinic acetylcholine receptor sites involved in the release of [3H]noradrenaline were assessed in rat hippocampus. The effect of nicotinic agonists to induce [3H]noradrenaline release was examined in superfused slices. The nicotinic agonists (-)-epibatidine, (+)-anatoxin-a, ...

journal_title：Neuroscience

authors： Sershen H,Balla A,Lajtha A,Vizi ES

更新日期：1997-03-01 00:00:00

abstract：:The p38 member of the mitogen-activated protein kinase superfamily is engaged by phosphorylation in response to environmental stress signals, and may have either permissive or inhibitor roles upon cell proliferation. The cell cycle in the proliferative zone of the retina is tightly controlled and proceeds in synchrony...

journal_title：Neuroscience

authors： Campos CB,Bédard PA,Linden R

更新日期：2002-01-01 00:00:00

abstract：:The circadian pacemaker of the suprachiasmatic nuclei is a complex multioscillator system, which controls circadian and seasonal rhythmicity. A number of clock genes have been identified that play a key role in the generation of circadian rhythms. These clock genes are expressed in a circadian manner as has been shown...

journal_title：Neuroscience

authors： Schaap J,Albus H,Eilers PH,Détári L,Meijer JH

更新日期：2001-01-01 00:00:00

abstract：:In dissociated hypothalamic cell cultures of 16-day mouse embryos, growing in chemically defined medium, the catecholaminergic neurons were identified by autoradiography after labelling with [3H]dopamine and by immunocytochemistry with an anti-tyrosine hydroxylase antibody. Using selective inhibitors of amine transpor...

journal_title：Neuroscience

authors： Puymirat J,Barret A,Picart R,Vigny A,Loudes C,Faivre-Bauman A,Tixier-Vidal A

更新日期：1983-11-01 00:00:00

abstract：:Lipid peroxidation disrupts membrane integrity and causes structural and functional alterations in ischemic tissues. Taurine and ketamine are putative ischemic protectants that affect Ca2+ influx. Here we report the influence of these compounds on lipid peroxidation in subcellular fractions, isolated cells and intact ...

journal_title：Neuroscience

authors： Zhou M,Ma T,Tseng MT

更新日期：1991-01-01 00:00:00