Detection of homovanillic acid in vivo using microcomputer-controlled voltammetry: simultaneous monitoring of rat motor activity and striatal dopamine release.

abstract：:The uptake and release of catecholamines was investigated in the isolated perfused adrenal gland of the rat after preloading the preparation with [3H]norepinephrine, and the effects of various agents were examined on the stimulation-evoked secretion of catecholamines and total tritium. Large quantities of tritium were...

journal_title：Neuroscience

authors： Wakade AR,Malhotra RK,Wakade TD,Dixon WR

更新日期：1986-08-01 00:00:00

abstract：:Exposure of male Syrian hamsters to a short daylength of 8L:16D leads to gonadal regression. This effect of photoperiod was prevented by pinealectomy or chronic exposure of the brain to exogenous melatonin delivered from in-dwelling cannulae. However, the effect of melatonin was dependent on the neural site of applica...

journal_title：Neuroscience

authors： Hastings MH,Walker AP,Roberts AC,Herbert J

更新日期：1988-03-01 00:00:00

abstract：:Histamine H(3) autoreceptors induce a negative feedback on histamine synthesis and release. While it is known that cAMP/cAMP dependent protein kinase (PKA) and Ca(2+)/CaMKII transduction pathways mediate H(3) effects on histamine synthesis, the pathways regulating neuronal histamine release are poorly known. Given the...

journal_title：Neuroscience

authors： Moreno-Delgado D,Gómez-Ramírez J,Torrent-Moreno A,González-Sepúlveda M,Blanco I,Ortiz J

更新日期：2009-12-15 00:00:00

abstract：:Our previous results obtained by lesioning or stimulating the ventrolateral part of the lateral septum and the bed nuclei of the stria terminalis suggested that this area is involved in the control of milk ejection pattern in rats. The present study was undertaken with the aim of testing ventrolateral part of the late...

journal_title：Neuroscience

authors： Lambert RC,Moos FC,Ingram CD,Wakerley JB,Kremarik P,Guerné Y,Richard P

更新日期：1993-05-01 00:00:00

abstract：:Thrombin plays important roles in the pathology of intracerebral hemorrhage (ICH). The recruitment of activated microglia, accompanied by thrombin-induced phosphorylation of the mitogen-activated protein kinase (MAPK) family, contributes to ICH-associated neuron loss. Here we investigated the possibility that sesamin,...

journal_title：Neuroscience

authors： Ohnishi M,Monda A,Takemoto R,Matsuoka Y,Kitamura C,Ohashi K,Shibuya H,Inoue A

更新日期：2013-03-01 00:00:00

abstract：:Nitric oxide is thought to play an important role in multiple forms of use-dependent synaptic plasticity, including that which follows noxious peripheral stimulation. This suggests that development of nociception-induced neuroplasticity should be impaired in transgenic animals lacking the neuronal form of nitric oxide...

journal_title：Neuroscience

authors： Crosby G,Marota JJ,Huang PL

更新日期：1995-12-01 00:00:00

abstract：:The main neuronal population of the striatum is composed of the medium spiny neurones (MSNs). In fact several sub-populations of MSNs can be distinguished according to the striatal compartment (striosomes and matrix) to which they belong, their afferents and their sites of projection, their biochemical markers and the...

journal_title：Neuroscience

authors： Venance L,Glowinski J

更新日期：2003-01-01 00:00:00

abstract：:Inflammatory damage following ICH is often attributed to microglia/macrophage activation. In many diseases, IL-4 has been proven to switch microglia/macrophages from the pro-inflammatory to the anti-inflammatory subtype. However, the role and underlying mechanism of IL-4 in ICH, especially in neuroprotection, remain u...

journal_title：Neuroscience

authors： He Y,Gao Y,Zhang Q,Zhou G,Cao F,Yao S

更新日期：2020-06-15 00:00:00

abstract：:Synapse formation in CNS neurons requires appropriate sorting and clustering of neurotransmitter receptors and associated proteins at postsynaptic sites. In GABAergic synapses, clustering of GABA(A) receptors requires gephyrin, but it is not known whether presynaptic signals are also involved in this process. To inves...

journal_title：Neuroscience

authors： Studler B,Fritschy JM,Brünig I

更新日期：2002-01-01 00:00:00

abstract：:Electroconvulsive therapy has been commonly applied in the treatment of refractory depression, but its cognitive side effects are noticed and restrict its application. The molecular mechanisms underlying the side effects remain elusive, and there is no efficient prevention. By employing a recognized electroconvulsive ...

journal_title：Neuroscience

authors： Yao Z,Guo Z,Yang C,Tian Q,Gong CX,Liu G,Wang JZ

更新日期：2010-06-30 00:00:00

abstract：:Sleep is strongly implicated in learning, especially in the reprocessing of recently acquired memory. Children with intellectual disability (ID) tend to have sleep-wake disturbances, which may contribute to the pathophysiology of the disease. Given that sleep is partly controlled by the circadian clock, we decided to ...

journal_title：Neuroscience

authors： Renaud J,Dumont F,Khelfaoui M,Foisset SR,Letourneur F,Bienvenu T,Khwaja O,Dorseuil O,Billuart P

更新日期：2015-11-12 00:00:00

abstract：:In the present study plastic neural responses to N-methyl-D-aspartate-induced excitotoxic lesions and the neuroprotective effects of the L-type voltage-dependent Ca(2+) channel antagonist nimodipine were investigated in the rat magnocellular nucleus basalis. Assessment of spontaneous behaviour in the elevated plus maz...

journal_title：Neuroscience

authors： Harkany T,Dijkstra IM,Oosterink BJ,Horvath KM,Abrahám I,Keijser J,Van der Zee EA,Luiten PG

更新日期：2000-01-01 00:00:00

abstract：:Patterns of bimanual coordination in which homologous muscles are simultaneously active are more stable than those in which homologous muscles are engaged in an alternating fashion. This may be attributable to the stronger involvement of the dominant motor cortex in ipsilateral hand movements via interaction with the ...

journal_title：Neuroscience

authors： Aramaki Y,Honda M,Sadato N

更新日期：2006-09-15 00:00:00

abstract：:Conduction time is typically ignored in computational models of neural network function. Here we consider the effects of conduction delays on the synchrony of neuronal activity and neural oscillators, and evaluate the consequences of allowing conduction velocity (CV) to be regulated adaptively. We propose that CV vari...

journal_title：Neuroscience

authors： Pajevic S,Basser PJ,Fields RD

更新日期：2014-09-12 00:00:00

abstract：:Ultrastructural degeneration studies were carried out on the cat trochlear nucleus following lesion of the vestibulo-trochlear pathway in order to characterize the location and type of presynaptic endings involved in this pathway. Four types of boutons are found in the normal trochlear nucleus. Types I and II are larg...

journal_title：Neuroscience

authors： Bak IJ,Baker R,Choi WB,Precht W

更新日期：1976-12-01 00:00:00

abstract：:The effect of pairing two vibrissa stimulations on unit responses of the barrel field of the somatosensory cortex were studied in partially restrained but awake and undrugged rats. Before pairing, one of the stimulations (S2) evoked a stable, short-latency and excitatory response from the recorded unit. Depending on t...

journal_title：Neuroscience

authors： Delacour J,Houcine O,Talbi B

更新日期：1987-10-01 00:00:00

abstract：:Direct injections into the cerebroventricles have been extensively utilized in neurophysiological studies. Mapping the distribution of injectate after intracerebroventricular injection has been made only by post mortem analysis, and the dynamic distribution of injectate within the brain has not been well characterized...

journal_title：Neuroscience

authors： Bui JD,Nammari DR,Buckley DL,Inglis BA,Silver XS,Mareci TH,Phillips MI

更新日期：1999-03-01 00:00:00

abstract：:In mice carrying the weaver mutation there is a spontaneous degeneration of dopaminergic neurons that is heterogeneous among cell groups: nigrostriatal neurons are more affected than mesolimbic neurons, while involvement of the mesocortical system is controversial. We questioned whether the pattern of cell loss in mes...

journal_title：Neuroscience

authors： Gaspar P,Ben Jelloun N,Febvret A

更新日期：1994-07-01 00:00:00

abstract：:Recent studies investigating neural correlates of human thirst have identified various subcortical and telencephalic brain areas. The experience of thirst represents a homeostatic emotion and a state that slowly evolves over time. Therefore, the present study aims at systematically examining cerebral perfusion during ...

journal_title：Neuroscience

authors： Meier L,Federspiel A,Jann K,Wiest R,Strik W,Dierks T

更新日期：2018-07-15 00:00:00

abstract：:Activation of the adenosine A(2A) receptor (A(2A)R) at the time of reperfusion has been shown to reduce ischemia-reperfusion injury in peripheral tissues and spinal cord. In this study we show that treating mice with the A(2A)R agonist, 4-{3-[6-amino-9-(5-cyclopropylcarbamoyl-3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-pu...

journal_title：Neuroscience

authors： Li Y,Oskouian RJ,Day YJ,Rieger JM,Liu L,Kern JA,Linden J

更新日期：2006-09-15 00:00:00

abstract：:Opiate addiction is a chronic medical disorder characterized by drug tolerance and dependence, behavioral sensitization, vulnerability to compulsive relapse, and high mortality. In laboratory animals, the potential effect of opiate drugs to induce cell death by apoptosis is a controversial topic. This postmortem human...

journal_title：Neuroscience

authors： García-Fuster MJ,Ramos-Miguel A,Rivero G,La Harpe R,Meana JJ,García-Sevilla JA

更新日期：2008-11-11 00:00:00

abstract：:Considerable evidence suggests that a dysfunction of the dopamine and serotonin (5-hydroxytryptamine or 5-HT) neurotransmitter systems contributes to a diverse range of pathological conditions including schizophrenia, depression and drug abuse. Recent electrophysiological and behavioral studies suggest that 5-HT modul...

journal_title：Neuroscience

authors： Nocjar C,Roth BL,Pehek EA

更新日期：2002-01-01 00:00:00

abstract：:The GABAergic innervation of the extraocular motor nuclei in the cat was evaluated using postembedding immunocytochemical techniques. The characterization of GABA-immunoreactive terminals in the oculomotor nucleus was carried out at the light and electron microscopic levels. GABA-immunopositive puncta suggestive of bo...

journal_title：Neuroscience

authors： de la Cruz RR,Pastor AM,Martínez-Guijarro FJ,López-García C,Delgado-García JM

更新日期：1992-12-01 00:00:00

abstract：:Neuroinflammation is associated with increased vulnerability to diverse psychiatric conditions, including treatment-resistant major depressive disorder (MDD). Here we assessed whether high fat diet (HFD) induced neuroinflammation may be suitable to model a treatment-resistant depressive-like brain state in mice. Male ...

journal_title：Neuroscience

authors： Feng M,Crowley NA,Patel A,Guo Y,Bugni SE,Luscher B

更新日期：2019-05-15 00:00:00

abstract：:Rats were given bilateral lesions of the motor cortex on the tenth day of life, and then received a daily subcutaneously injection of either basic fibroblast growth factor (FGF-2) or vehicle for 7 consecutive days. In adulthood, they were trained and assessed on a skilled forelimb reaching task. Although all lesion gr...

journal_title：Neuroscience

authors： Monfils MH,Driscoll I,Vandenberg PM,Thomas NJ,Danka D,Kleim JA,Kolb B

更新日期：2005-01-01 00:00:00

abstract：:Opioid binding sites were localized in cryostat sections of guinea-pig brain by in vitro autoradiography using (-)-[3H]bremazocine. Quantification of binding sites in gray matter was accomplished using standard samples of tritium mixed in brain gray matter. The binding sites in fiber tracts were quantified using stand...

journal_title：Neuroscience

authors： Foote RW

更新日期：1987-01-01 00:00:00

abstract：:There is a consensus that active (REM) sleep (AS) is controlled by cholinergic projections from the laterodorsal and pedunculopontine tegmental nuclei (LDT/PPT) to neurons in the nucleus pontis oralis (NPO) that generate AS (i.e. AS-Generator neurons). The present study was designed to provide evidence that other proj...

journal_title：Neuroscience

authors： Xi M,Fung SJ,Sampogna S,Chase MH

更新日期：2011-12-01 00:00:00

abstract：:The influence of intra-arterial injections of 5-hydroxytryptamine, histamine and prostaglandin E2 on afferent impulse activity of mesenteric nerves of small intestine was studied. In anaesthetized cats 5-hydroxytryptamine (10(-5)-10(-4) M) and histamine (10(-5)-10(-3) M) were shown to increase the impulse activity in ...

journal_title：Neuroscience

authors： Akoev GN,Filippova LV,Sherman NO

更新日期：1996-04-01 00:00:00

abstract：:The distribution of [125I]omega-conotoxin GVIA binding sites, the putative voltage-sensitive calcium channels, was studied by an autoradiographic method in the rat brain. The toxin binding sites were distributed throughout the brain in a highly heterogeneous manner. The highest density of the binding sites was observe...

journal_title：Neuroscience

authors： Takemura M,Kiyama H,Fukui H,Tohyama M,Wada H

更新日期：1989-01-01 00:00:00

abstract：:PSD-95/SAP90, a molecular scaffold protein, attaches the N-methyl-D-aspartate receptor to cellular signaling pathways through PSD-95/DLG/Z0-1 domain interactions at neuronal synapses.(5,9) This suggests that PSD-95/SAP90 might be involved in many physiological and pathophysiological actions triggered via the N-methyl-...

journal_title：Neuroscience

authors： Tao YX,Huang YZ,Mei L,Johns RA

更新日期：2000-01-01 00:00:00