Mast cell mediators excite the afferents of cat small intestine.

abstract：:Drug addiction behavior that is established and maintained by psychostimulants has been shown to be associated with the expression of brain-derived neurotrophic factor (BDNF) in the mesolimbic dopamine (DA) system. Cocaine has been used for most prior studies testing this effect of psychostimulants and therefore relat...

journal_title：Neuroscience

authors： Shen YL,Chang TY,Chang YC,Tien HH,Yang FC,Wang PY,Liao RM

更新日期：2014-03-28 00:00:00

abstract：:How seizures arise and recur in epilepsy is unknown. Recent genetic, pharmacological and electrophysiological data indicate a significant but undisclosed role for voltage-dependent calcium channels. Since the contribution such channels make to nerve function reflects the targeting of discrete subtypes to distinct cell...

journal_title：Neuroscience

authors： Bernstein GM,Mendonça A,Wadia J,Burnham WM,Jones OT

更新日期：1999-01-01 00:00:00

abstract：:Ca(2+) influx through voltage-gated Ca(2+) channels is a fundamental signaling event in neurons; however, non-traditional routes, such as non-selective cation channels, also permit Ca(2+) entry. The present study examines the Ca(2+) permeability of a cation channel that drives an afterdischarge in Aplysia bag cell neu...

journal_title：Neuroscience

authors： Geiger JE,Hickey CM,Magoski NS

更新日期：2009-09-15 00:00:00

abstract：:Recent studies investigating neural correlates of human thirst have identified various subcortical and telencephalic brain areas. The experience of thirst represents a homeostatic emotion and a state that slowly evolves over time. Therefore, the present study aims at systematically examining cerebral perfusion during ...

journal_title：Neuroscience

authors： Meier L,Federspiel A,Jann K,Wiest R,Strik W,Dierks T

更新日期：2018-07-15 00:00:00

abstract：:Using data from time-resolved cortical stimulation, intracranial neural recordings, and focal surgical resections, Lee et al. (2018) demonstrate that a small area within left posterior superior temporal gyrus (pSTG) supports the ability to produce functional morphemes but not other basic aspects of language production...

journal_title：Neuroscience

authors： Fedorenko E,Williams ZM,Ferreira VS

更新日期：2018-11-10 00:00:00

abstract：:Androgens are known to affect cognitive and mnemonic aspects of spatial processing. The cholinergic system is thought to play an important role in cognition and memory, but little is known about the interaction between androgen and cholinergic neurons. The present study focused on the effects of testosterone on the ch...

journal_title：Neuroscience

authors： Nakamura N,Fujita H,Kawata M

更新日期：2002-01-01 00:00:00

abstract：:Brain activities in response to acupuncture have been investigated in multiple studies; however, the neuromechanisms of low- and high-frequency transcutaneous electric acupoint stimulation (TEAS) analgesia are unclear. This work aimed to investigate how brain activity and the analgesic effect changed across 30-min low...

journal_title：Neuroscience

authors： Jiang Y,Liu J,Liu J,Han J,Wang X,Cui C

更新日期：2014-05-30 00:00:00

abstract：:Dopaminergic axons arising from midbrain nuclei innervate the mammalian and avian telencephalon with heterogeneous regional and laminar distributions. In primate, rodent, and avian species, the neuromodulator dopamine is low or almost absent in most primary sensory areas and is most abundant in the striatal parts of t...

journal_title：Neuroscience

authors： Durstewitz D,Kröner S,Hemmings HC Jr,Güntürkün O

更新日期：1998-04-01 00:00:00

abstract：:Long non-coding RNA MALAT1 was previously revealed to express abnormally in animal and cellular models of stroke, suggesting its indispensable role in stroke. The aims of the present study were to further investigate the functions of MALAT1 and to elucidate the underlying molecular mechanisms. Oxygen glucose deprivati...

journal_title：Neuroscience

authors： Gao C,Zhang CC,Yang HX,Hao YN

更新日期：2020-05-21 00:00:00

abstract：:Neurotransmitter and headache target localization in the trigeminal ganglia (TG) might increase the understanding of sites of action, and mechanisms related to headache therapy. The overall aim of the study was to investigate the presence of migraine targets in the TG with particular emphasis on pituitary adenylate cy...

journal_title：Neuroscience

authors： Frederiksen SD,Warfvinge K,Ohlsson L,Edvinsson L

更新日期：2018-11-21 00:00:00

abstract：:The anxiolytic diazepam selectively inhibits psychological stress-induced autonomic and behavioral responses without causing noticeable suppression of other central performances. This pharmacological property of diazepam led us to the idea that neurons that exhibit diazepam-sensitive, psychological stress-induced acti...

journal_title：Neuroscience

authors： Lkhagvasuren B,Oka T,Nakamura Y,Hayashi H,Sudo N,Nakamura K

更新日期：2014-07-11 00:00:00

abstract：:The effects of glial cell line-derived neurotrophic factor on axonal outgrowth and apoptosis were studied in vitro using explanted dorsal root ganglia-peripheral nerve preparations of adult mice. In gels of matrigel or collagen type 1, glial cell line-derived neurotrophic factor increased both the numbers and lengths ...

journal_title：Neuroscience

authors： Leclere P,Ekström P,Edström A,Priestley J,Averill S,Tonge DA

更新日期：1998-01-01 00:00:00

abstract：:Locomotor stepping in the Nembutal-anesthetized rat was elicited by electrical stimulation of either of two sites in the right or left posterolateral hypothalamus. Essential midbrain loci were identified by reversibly blocking the elicited locomotion through local injections of the anesthetic procaine (15%, 0.5 microl...

journal_title：Neuroscience

authors： Levy DI,Sinnamon HM

更新日期：1990-01-01 00:00:00

abstract：:The pontine micturition center or Barrington's nucleus (BN) - besides regulating micturition - co-regulates the activity of other pelvic viscera such as the colon and genitals. At present, this issue is gaining particular importance due to: (i) recent findings of α-synuclein in BN, (ii) known urinary dysfunction in pa...

journal_title：Neuroscience

authors： Blanco L,Ros CM,Tarragón E,Fernández-Villalba E,Herrero MT

更新日期：2014-04-25 00:00:00

abstract：:Early life experiences, particularly the experience with parents, are crucial to phenotypic outcomes in both humans and animals. Although the effects of maternal deprivation on offspring well-being have been studied, paternal deprivation (PD) has received little attention despite documented associations between father...

journal_title：Neuroscience

authors： Tabbaa M,Lei K,Liu Y,Wang Z

更新日期：2017-02-20 00:00:00

abstract：:In anaesthetized albino rabbits, the cerebellar flocculus was systematically mapped with a glass microelectrode to identify the location of Purkinje cells that inhibit specific vestibulo-ocular reflex pathways. The effects of microstimulation of the flocculus Purkinje cell layer on vestibular nerve-evoked reflexes to ...

journal_title：Neuroscience

authors： Ito M,Orlov I,Yamamoto M

更新日期：1982-07-01 00:00:00

abstract：:The peripheral sympathetic and parasympathetic cholinergic innervation was investigated with antibodies directed against the C-terminus of the rat vesicular acetylcholine transporter. Immunohistochemistry for the vesicular acetylcholine transporter resulted in considerably more detailed visualization of cholinergic te...

journal_title：Neuroscience

authors： Schäfer MK,Eiden LE,Weihe E

更新日期：1998-05-01 00:00:00

abstract：:Administration of kainic acid induces acute seizures that result in the loss of neurons, gliosis and reorganization of mossy fiber pathways in the hippocampus resembling those observed in human temporal lobe epilepsy. Although these structural changes have been well characterized, the mechanisms underlying the degener...

journal_title：Neuroscience

authors： Banerjee M,Sasse VA,Wang Y,Maulik M,Kar S

更新日期：2015-01-22 00:00:00

abstract：:The basal forebrain cholinergic system is a critical component of the neurobiological substrates underlying attentional function. Orexin neurons are important for arousal and maintenance of wakefulness and are found in the area of the hypothalamus previously shown to project to the basal forebrain. We used dual-probe ...

journal_title：Neuroscience

authors： Fadel J,Pasumarthi R,Reznikov LR

更新日期：2005-01-01 00:00:00

abstract：:To investigate the minimum neuron and neurite densities required for synchronized bursts, we cultured rat cortical neurons on planar multi-electrode arrays (MEAs) at five plating densities (2500, 1000, 500, 250, and 100 cells/mm(2)) using two culture media: Neuron Culture Medium and Dulbecco's Modified Eagle Medium su...

journal_title：Neuroscience

authors： Ito D,Tamate H,Nagayama M,Uchida T,Kudoh SN,Gohara K

更新日期：2010-11-24 00:00:00

abstract：:Sensory neurons express purinergic P2X receptors on their central and peripheral terminals as well as their cell bodies. ATP activation of these receptors drives action potential firing and glutamate release with potentially important consequences for sensory function. Here we show ATP-gated currents activated in cult...

journal_title：Neuroscience

authors： Labrakakis C,Gerstner E,MacDermott AB

更新日期：2000-01-01 00:00:00

abstract：:Working memory has often been modeled and conceptualized as a kind of binary (bistable) memory switch, where stimuli turn on plateau-like persistent activity in subsets of cells, in line with many in vivo electrophysiological reports. A potentially related form of bistability, termed up- and down-states, has been stud...

journal_title：Neuroscience

authors： Durstewitz D,Seamans JK

更新日期：2006-04-28 00:00:00

abstract：:Alternative motor responses can be prepared in parallel. Here, we used electroencephalography (EEG) to test whether the parallel preparation of alternative response options is modulated by their relative value. Participants performed a choice response task with three potential actions: isometric contraction of the lef...

journal_title：Neuroscience

authors： Reuter EM,Marinovic W,Beikoff J,Carroll TJ

更新日期：2018-03-15 00:00:00

abstract：:We have examined the effect of acrolein, an aldehyde product of lipid peroxidation, on axons in isolated guinea-pig spinal cord white matter. We found that 200 microM acrolein, but not 50 microM, induced a time-dependent loss of compound action potential conduction. Such conduction loss was irreversible within 1 h aft...

journal_title：Neuroscience

authors： Shi R,Luo J,Peasley M

更新日期：2002-01-01 00:00:00

abstract：:In this study co-localization of galanin- with calcitonin gene-related peptide (CGRP)-like immunoreactivity was examined in dorsal root ganglion neurons 14 days after sciatic nerve cut using a laser scanning confocal microscope. CGRP- and galanin-like immunoreactivities were also analysed in the dorsal horn of the spi...

journal_title：Neuroscience

authors： Zhang X,Bean AJ,Wiesenfeld-Hallin Z,Xu XJ,Hökfelt T

更新日期：1995-02-01 00:00:00

abstract：:We have previously observed that migraine attacks impervious to triptan therapy were readily terminated by subsequent i.v. administration of the non-steroidal anti-inflammatory drug (NSAID) ketorolac. Since such attacks were associated with periorbital allodynia--a symptom of central sensitization--we examined whether...

journal_title：Neuroscience

authors： Jakubowski M,Levy D,Kainz V,Zhang XC,Kosaras B,Burstein R

更新日期：2007-08-24 00:00:00

abstract：:Acute low back pain (LBP) is associated with differential changes in motor coordination of deep and superficial trunk muscles. Whether this is related to differential changes in excitability of descending corticomotor inputs remains unclear and was investigated in nine healthy individuals. Fine-wire i.m. electrodes we...

journal_title：Neuroscience

authors： Tsao H,Tucker KJ,Hodges PW

更新日期：2011-05-05 00:00:00

abstract：:Environmental enrichment of laboratory animals leads to multi-faceted changes to physiology, health and disease prognosis. An important and under-appreciated factor in enhancing cognition through environmental manipulation may be improved basic sensory function. Previous studies have highlighted changes in cortical se...

journal_title：Neuroscience

authors： Devonshire IM,Dommett EJ,Grandy TH,Halliday AC,Greenfield SA

更新日期：2010-10-13 00:00:00

abstract：:It is not known why expression of a protein with an expanded polyglutamine region is pathogenic in spinocerebellar ataxia, Huntington's disease and several other neurodegenerative diseases. Dietary supplementation with creatine improves survival and motor performance and delays neuronal atrophy in the R6/2 transgenic ...

journal_title：Neuroscience

authors： Kaemmerer WF,Rodrigues CM,Steer CJ,Low WC

更新日期：2001-01-01 00:00:00

abstract：:It has been observed that motor neuron death is induced in adult rats by ventral root avulsion which involves pulling out the spinal cord root. Since motor neurons are reported to be selectively vulnerable to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor-mediated injury in vitro, we investigated chang...

journal_title：Neuroscience

authors： Nagano I,Murakami T,Shiote M,Abe K,Itoyama Y

更新日期：2003-01-01 00:00:00