abstract：:As new tests and technologies advance our understanding and diagnostic capabilities of the severe acute respiratory syndrome coronavirus 2 and the coronavirus disease 2019, they must be appropriately validated to make sure test performance is following manufacturer claims. In this study, we evaluated the Vazyme 2019-n...

journal_title：Diagnostic microbiology and infectious disease

authors： Xie X,Nielsen MC,Muruato AE,Fontes-Garfias CR,Ren P

更新日期：2021-02-01 00:00:00

abstract：:This study aims to identify factors associated with duration of intravenous (IV) and follow-on oral antibiotic therapy for cellulitis in patients treated through outpatient parenteral antimicrobial therapy (OPAT). A retrospective review of episodes of cellulitis treated over a year (January 2018-January 2019) at a lar...

journal_title：Diagnostic microbiology and infectious disease

authors： Palit J,Cole J,Durojaiye OC

更新日期：2021-01-06 00:00:00

abstract：:We evaluated the performance of three chromogenic media (BBL CHROMagar™ Staph aureus, ChromID™ S. aureus SAID, ChromID™ S. aureus Elite SAIDE) for the isolation of Staphylococcus aureus in respiratory samples in patients with cystic fibrosis in comparison with CNA media. We reported a similar ability of the four media...

journal_title：Diagnostic microbiology and infectious disease

authors： Dyon-Tafani V,Josse J,Safrani-Lahyani J,Assant-Trouillet S,Chiganne M,Vincent F,Montclos MP,Doleans-Jordheim A,Laurent F

更新日期：2021-01-01 00:00:00

abstract：:A shift to Candida non-albicans infections has been noted during the last years, and the emergence of multi-resistant Candida auris has complicated their management. The aim of this study was first to compare the performance of the novel chromogenic medium CHROMagar™ Candida Plus (CHROMagar, France) with CHROMagar™ Ca...

journal_title：Diagnostic microbiology and infectious disease

authors： Mulet Bayona JV,Salvador García C,Tormo Palop N,Gimeno Cardona C

更新日期：2020-12-01 00:00:00

abstract：:Pulmonary tuberculosis (TB) is one of the common risk factors for chronic pulmonary aspergillosis (CPA). A positive Aspergillus IgG is a key element of the diagnosis of CPA but this has not been studied in Indonesia. We conducted studies with patients at the end of TB therapy in Indonesia. We performed receiver operat...

journal_title：Diagnostic microbiology and infectious disease

authors： Setianingrum F,Rozaliyani A,Syam R,Adawiyah R,Tugiran M,Sari CYI,Burhan E,Wahyuningsih R,Rautemaa-Richardson R,Denning DW

更新日期：2020-11-01 00:00:00

abstract：:Although multiple antimicrobial resistance (AMR) determinants can confer the same in vitro antimicrobial susceptibility testing (AST) phenotype, their differing effect on optimal therapeutic choices is uncertain. Using a large population-based collection of clinical strains spanning a 3.5-year period, we applied WGS t...

journal_title：Diagnostic microbiology and infectious disease

authors： Hujer AM,Long SW,Olsen RJ,Taracila MA,Rojas LJ,Musser JM,Bonomo RA

更新日期：2020-11-01 00:00:00

abstract：:COVID-19 greatly disrupted the global supply chain of nasopharyngeal swabs, and thus new products have come to market with little data to support their use. In this prospective study, 2 new 3D printed nasopharyngeal swab designs were evaluated against the standard, flocked nasopharyngeal swab for the diagnosis of COVI...

journal_title：Diagnostic microbiology and infectious disease

authors： Oland G,Garner O,de St Maurice A

更新日期：2020-10-22 00:00:00

abstract：:Gepotidacin (GSK2140944) is a first in class, novel triazaacenaphthylene bacterial type II topoisomerase inhibitor in Phase 3 clinical development for the treatment of gonorrhea and uncomplicated urinary tract infections (acute cystitis). This study tested the equivalency of minimal inhibitory concentrations (MICs) ob...

journal_title：Diagnostic microbiology and infectious disease

authors： Arends SJR,Canino MA,Mendes R,Scangarella-Oman NE,Flamm RK

更新日期：2020-10-01 00:00:00

abstract：:The analytical performance of the FDA-cleared AIX1000 automated RPR testing platform was evaluated in comparison to manual RPR card testing. Eight hundred thirty-three patient serum samples were analyzed, 87 samples were positive by the AIX1000, 108 were positive by the manual test method; overall agreement between me...

journal_title：Diagnostic microbiology and infectious disease

authors： Pyden A,Kang AD,Amato S,Dutta S,Berg G,Riedel S

更新日期：2020-08-01 00:00:00

abstract：:Development and standardization of simple, timely, and cost-effective antibiotic susceptibility assays are much needed to address the emergence of global resistance. The use of matrix-assisted laser desorption/ionization time of flight mass spectrometry is routine for bacterial identification. This study evaluated 2 a...

journal_title：Diagnostic microbiology and infectious disease

authors： Horseman TS,Lustik MB,Fong KSK

更新日期：2020-08-01 00:00:00

abstract：:Escherichia coli ST131, with its multidrug-resistance-associated H30R1 and H30Rx clonal subsets within the H30R subclone, causes most antimicrobial-resistant E. coli infections. The activity of ceftazidime-avibactam (CZA) against ST131 strains is undefined. We determined CZA MICs for 595 E. coli clinical isolates from...

journal_title：Diagnostic microbiology and infectious disease

authors： Johnston BD,Thuras PD,Johnson JR

更新日期：2020-07-01 00:00:00

abstract：:Clostridium difficile (CD) diagnosis is very varied and under discussion. Different research groups disagree on the clinical significance of patients with negative direct toxin and positive polymerase chain reaction (PCR) or even more with direct toxin and glutamate dehydrogenase (GDH) both negatives, but CD detected ...

journal_title：Diagnostic microbiology and infectious disease

authors： Olmedo M,Alcalá L,Valerio M,Marín M,Onori R,Reigadas E,Muñoz P,Bouza E

更新日期：2020-07-01 00:00:00

abstract：:We report a case of pulmonary mucormycosis in a patient with T-cell acute lymphoblastic leukemia. The diagnosis of mucormycosis was initially based on mycological examination of a pulmonary specimen. However, we describe how it could have been made 2 months earlier using polymerase chain reaction assays targeting Muco...

journal_title：Diagnostic microbiology and infectious disease

authors： Hoffmann C,Guillerm G,Le Pape P,Carausu L,Lavergne RA,Nevez G,Le Gal S

更新日期：2020-06-01 00:00:00

abstract：:The aim of this study was to evaluate the clinical value of partial 16S/18S rRNA gene sequencing with the commercial kit Micro-Dx™ used with the SelectNA™plus instrument on culture-negative samples. A retrospective study of microbiological and clinical data from a 2.5-year period was performed. Assessment of the clini...

journal_title：Diagnostic microbiology and infectious disease

authors： Marbjerg LH,Holzknecht BJ,Dargis R,Dessau RB,Nielsen XC,Christensen JJ

更新日期：2020-06-01 00:00:00

abstract：:Despite improvement in vaccinations, Hepatitis B remains a major health concern due to the difficulty of prevention even in low endemic areas such as Europe. In this report we describe the performance characteristics of the new HBsAg Next Qualitative and HBsAg Next Confirmatory assays designed for blood screening and ...

journal_title：Diagnostic microbiology and infectious disease

authors： Sickinger E,Braun HB,Meyer T,Schmid K,Daghfal D,Oer M,Schultess J

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVES:We assessed the analytical and clinical performance of the Lumipulse® G HBcAb-N (Fujirebio, Japan) assay for IgG antibodies to hepatitis B core antigen (anti-HBc IgG) measurement in serum of subjects with overt and occult HBV infection (OBI). MATERIALS/METHODS:Serum anti-HBc IgG was assessed in 181 anti-HBc...

journal_title：Diagnostic microbiology and infectious disease

authors： Caviglia GP,Olivero A,Ciancio A,Tandoi F,Troshina G,Rosso C,Abate ML,Younes R,Ribaldone DG,Smedile A,Rizzetto M,Romagnoli R,Saracco GM,Bugianesi E

更新日期：2020-04-01 00:00:00

abstract：:We evaluated the performance of the automated BD Phoenix CPO Detect test (BD-CPO test) for detection and Ambler classification of carbapenemases in Enterobacteriaceae, P.aeruginosa and A.baumannii complex. A collection of 287 Gram-negative clinical isolates, with a reduced susceptibility to at least one carbapenem inc...

journal_title：Diagnostic microbiology and infectious disease

authors： Saad Albichr I,Anantharajah A,Dodémont M,Hallin M,Verroken A,Rodriguez-Villalobos H

更新日期：2020-02-01 00:00:00

abstract：:Two linezolid-resistant and teicoplanin-intermediate Staphylococcus epidermidis strains were isolated from blood cultures in China. The 2 S. epidermidis strains were methicillin-resistant and showed multidrug-resistance patterns; in addition, population analysis profiling/area under the curve (PAP/AUC) result showed h...

journal_title：Diagnostic microbiology and infectious disease

authors： Liu C,Chen C,Ye Y,Li X,Sun J,Xu L,Ming L

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:We compared changes in antibiotics in patients diagnosed with noninvasive pneumococcal pneumonia (NPP) by pneumoccocal urinary antigen tests or respiratory cultures. METHODS:We compared patients diagnosed by pneumococcal urinary antigen tests or respiratory cultures that grew Streptococcus pneumoniae. We as...

journal_title：Diagnostic microbiology and infectious disease

authors： Banks R,Zappernick T,Wilson B,Perez F,Jump RLP

更新日期：2020-02-01 00:00:00

abstract：:Staphylococcus aureus and Staphylococcus epidermidis are leading pathogens of biofilm-related infections and represent the most common cause of osteomyelitis and biomedical implants infections. Biofilm-related infections usually require long-term antibiotic treatment, often associated to surgical interventions. Dalbav...

journal_title：Diagnostic microbiology and infectious disease

authors： Di Pilato V,Ceccherini F,Sennati S,D'Agostino F,Arena F,D'Atanasio N,Di Giorgio FP,Tongiani S,Pallecchi L,Rossolini GM

更新日期：2020-02-01 00:00:00

abstract：:An OXA-181 producing Escherichia coli isolate that went recurrently undetected directly from rectal swab sample using Xpert® Carba-R, was successfully detected using ertapenem supplemented broth enrichment followed by culture-based method. Our data suggest that implementation of culture-based methods plus enrichment m...

journal_title：Diagnostic microbiology and infectious disease

authors： Girlich D,Ouzani S,Langlois I,Begasse C,Arangia N,Fortineau N,Naas T,Dortet L

更新日期：2020-01-01 00:00:00

abstract：:This prospective study evaluated the ability of the qPCR Amplidiag® CarbaR+VRE assay to detect Carbapenemase-producing Gram-negative bacilli (CP-GNB) directly on 1830 rectal swabs extracted using the fully automated platform Amplidiag® Easy instrument. The Amplidiag® CarbaR+VRE assay gave a positive signal for 94 rect...

journal_title：Diagnostic microbiology and infectious disease

authors： Nadji S,Gaillot O,Hallaert C,Messaadi S,Loukili N,Naas T,Lemaître N

更新日期：2019-12-01 00:00:00

abstract：:The frequency and antimicrobial susceptibility of organisms causing bloodstream infections in the United States were evaluated by consecutively collecting (1/patient) 9210 bacterial isolates from 33 US medical centers in 2015-2017. Isolates were susceptibility tested by reference broth microdilution methods. Whole gen...

journal_title：Diagnostic microbiology and infectious disease

authors： Sader HS,Castanheira M,Streit JM,Flamm RK

更新日期：2019-11-01 00:00:00

abstract：:We analyzed sequences of graSR, vraSR, walKR and rpoB genes in hVISA from Brazil. Five isolates showed mutations in at least one gene. rpoB H481N and graS T224I were the most frequent mutations, followed by graR D148Q and walK A468T. Our study reinforces the heterogeneity of genetic patterns among hVISA. ...

journal_title：Diagnostic microbiology and infectious disease

authors： Silveira ACO,Caierão J,Silva CI,Anzai EK,McCulloch JA,d'Azevedo PA,Sincero TCM

更新日期：2019-11-01 00:00:00

abstract：:A novel New Delhi metallo-β-lactamase (NDM) variant, NDM-19, was identified in a carbapenem-resistant E. coli strain isolated from a subcutaneous infection of a laparotomy scar from an Egyptian patient in a Swiss hospital. NDM-19 is a derivative of NDM-7, from which it differs by a single amino acid substitution (Ala2...

journal_title：Diagnostic microbiology and infectious disease

authors： Mancini S,Keller PM,Greiner M,Bruderer V,Imkamp F

更新日期：2019-11-01 00:00:00

abstract：:T2 Magnetic Resonance Candida Panel (T2MR) detects Candida directly in blood. Rapid turnaround time and high negative predictive value make it a useful diagnostic test to support antifungal discontinuation. This retrospective quasi-experiment compared empiric anidulafungin days of therapy (DOTs) in intensive care unit...

journal_title：Diagnostic microbiology and infectious disease

authors： Gill CM,Kenney RM,Hencken L,Mlynarek ME,Alangaden GJ,Samuel LP,Davis SL

更新日期：2019-10-01 00:00:00

abstract：:The study evaluated the change in the clinical antifungal sensitivity profile of A. flavus strains after exposure to azole and benzimidazole fungicide. Exposure to fungicide altered the sensitivity profile for the antifungal itraconazole, voriconazole and posaconazole. This change was characterized by an increase in t...

journal_title：Diagnostic microbiology and infectious disease

authors： Meireles LM,de Araujo ML,Endringer DC,Fronza M,Scherer R

更新日期：2019-10-01 00:00:00

abstract：:The present multicentric (n = 11 laboratories) study aimed to identify conversion factors from copies/mL to international units (IU)/mL for the normalization of HCMV DNA load using the first WHO International Standard for HCMV nucleic acid amplification techniques and to enhance interlaboratory agreement of HCMV DNA q...

journal_title：Diagnostic microbiology and infectious disease

authors： Sidoti F,Piralla A,Costa C,Scarasciulli ML,Calvario A,Conaldi PG,Paba P,Perno CF,Gaeta A,Antonelli G,Sodano G,Santangelo R,Sanguinetti M,Vatteroni ML,Barzon L,Palù G,Abbate I,Capobianchi MR,Piccirilli G,Lazzarotto T

更新日期：2019-10-01 00:00:00

abstract：:Though the FilmArray GI Panel has a reported aggregate specificity and reproducibility of >97% and > 99%, respectively, the reproducibility is less understood in clinical practice. We measured the reproducibility of positive results for low-prevalence pathogens. Samples with positive results for selected targets were ...

journal_title：Diagnostic microbiology and infectious disease

authors： Hitchcock MM,Hogan CA,Budvytiene I,Banaei N

更新日期：2019-09-01 00:00:00

abstract：:This study was designed to evaluate the incidence of Mycoplasma pneumoniae infection in children with community-acquired lower respiratory tract infections (LRTIs). A total of 245 patients 6 months to 12 years of age were investigated for M. pneumoniae employing serological tests, polymerase chain reaction (PCR), nest...

journal_title：Diagnostic microbiology and infectious disease

authors： Kumar S,Garg IB,Sethi GR

更新日期：2019-09-01 00:00:00

abstract：:This study aimed to assess the predictive factors of bacteremia due to hypermucoviscous Klebsiella pneumoniae (hvKP), as well as the mortality. The medical records of 114 patients with K. pneumoniae bacteremia who were divided into the hvKP (n = 24) and non-hvKP (n = 90) groups and were retrospectively reviewed. The m...

journal_title：Diagnostic microbiology and infectious disease

authors： Namikawa H,Yamada K,Sakiyama A,Imoto W,Yamairi K,Shibata W,Yoshii N,Niki M,Nakaie K,Oinuma KI,Tsubouchi T,Niki M,Tochino Y,Takemoto Y,Kaneko Y,Shuto T,Kakeya H

更新日期：2019-09-01 00:00:00

abstract：:We described a carbapenem-resistant Escherichia coli ST8499 strain producing New Delhi metallo-β-lactamase-13 (NDM-13) from patient in Korea. The isolate exhibited multidrug resistance, but remained susceptible to colistin and tigecycline. The blaNDM-13 gene was located on a 130-kb self-transmissible plasmid. This is ...

journal_title：Diagnostic microbiology and infectious disease

authors： Kim JS,Jin YH,Park SH,Han S,Kim HS,Park JH,Gong Y,An JH,Jung SW,Kim S,Kim J,Kim DW,Hong CK,Lee JH,Kim IY,Jung K

更新日期：2019-08-01 00:00:00

abstract：:The Alere-i™ Influenza A&B (Abbott), a nicking endonuclease amplification reaction test, has recently been improved in order to deliver results in a few minutes. Our field observation highlights two problems with this new version: improper interpretation of a test as valid despite improper reagent hydration and falsel...

journal_title：Diagnostic microbiology and infectious disease

authors： Otto MP,Toyer AL,Poggi C,Janvier F

更新日期：2019-08-01 00:00:00

abstract：:We describe a case report of a 56-year-old male with undiagnosed multiple myeloma who had severe sepsis associated with pneumonia, meningitis, polyarthritis, and osteomyelitis related to invasive "Haemophilus quentini" infection. The genus was misidentified as H. influenzae by the common bacterial identification syste...

journal_title：Diagnostic microbiology and infectious disease

authors： Cohen R,Finn T,Babushkin F,Karalnik S,Paikin S,Adler A,Geffen Y,Rokney A,Ron M

更新日期：2019-07-01 00:00:00

abstract：:Ceftobiprole medocaril, the prodrug of ceftobiprole, is an advanced-generation cephalosporin that is approved in many European and non-European countries for the treatment of adults with hospital-acquired pneumonia (excluding ventilator-associated pneumonia) and community-acquired pneumonia and is currently being eval...

journal_title：Diagnostic microbiology and infectious disease

authors： Pfaller MA,Flamm RK,Duncan LR,Shortridge D,Smart JI,Hamed KA,Mendes RE,Sader HS

更新日期：2019-07-01 00:00:00

abstract：INTRODUCTION:This study compares the detection of 14 common respiratory viruses by two different real-time reverse transcription polymerase chain reaction (rRT-PCR) methods: in house singleplex tests developed by the Centers for Disease Control and Prevention and the commercially available Fast Track Diagnostic (FTD®) ...

journal_title：Diagnostic microbiology and infectious disease

authors： Kenmoe S,Tcharnenwa C,Monamele GC,Kengne CN,Ripa MN,Whitaker B,Alroy KA,Balajee SA,Njouom R

更新日期：2019-07-01 00:00:00

abstract：:There are no studies evaluating the mechanisms driving linezolid resistance in nontuberculous mycobacteria. The novel mutations G2599A and A2137T in the 23S rRNA gene and mutations A439G and G443A in the rplD gene associated with linezolid resistance were identified in linezolid-resistant M. avium complex isolates. ...

journal_title：Diagnostic microbiology and infectious disease

authors： Kim SY,Jhun BW,Moon SM,Jeon K,Kwon OJ,Huh HJ,Lee NY,Shin SJ,Daley CL,Koh WJ

更新日期：2019-05-01 00:00:00

abstract：:Multidrug-resistant (MDR) and extensively drug-resistant (XDR) Mycobacterium tuberculosis cases in the Ukraine are increasing. Pyrazinamide (PZA) is critically important for first- and second-line tuberculosis (TB) treatment regimes. However, PZA drug susceptibility testing is time consuming and technically challengin...

journal_title：Diagnostic microbiology and infectious disease

authors： Daum LT,Konstantynovska OS,Solodiankin OS,Poteiko PI,Bolotin VI,Rodriguez JD,Gerilovych AP,Chambers JP,Fischer GW

更新日期：2019-04-01 00:00:00

abstract：:The aim of this study was to evaluate the serum levels of calprotectin and calgranulin C and routine biomarkers in patients with bacterial sepsis (BS). The initial serum concentrations of calprotectin and calgranulin C were significantly higher in patients with BS (n = 66) than in those with viral infections (n = 24) ...

journal_title：Diagnostic microbiology and infectious disease

authors： Bartáková E,Štefan M,Stráníková A,Pospíšilová L,Arientová S,Beran O,Blahutová M,Máca J,Holub M

更新日期：2019-03-01 00:00:00

abstract：:Haemophilus influenzae, a frequent colonizer of the respiratory tract, is the causative agent of several clinically important infections. In cases that require therapeutic intervention, laboratory susceptibility testing can detect beta-lactam antibiotic resistance and guide the best treatment course. In the absence of...

journal_title：Diagnostic microbiology and infectious disease

authors： Schotte L,Wautier M,Martiny D,Piérard D,Depypere M

更新日期：2019-03-01 00:00:00