Genetic mutations in linezolid-resistant Mycobacterium avium complex and Mycobacterium abscessus clinical isolates.

Abstract:

:There are no studies evaluating the mechanisms driving linezolid resistance in nontuberculous mycobacteria. The novel mutations G2599A and A2137T in the 23S rRNA gene and mutations A439G and G443A in the rplD gene associated with linezolid resistance were identified in linezolid-resistant M. avium complex isolates.

authors

Kim SY,Jhun BW,Moon SM,Jeon K,Kwon OJ,Huh HJ,Lee NY,Shin SJ,Daley CL,Koh WJ

doi

10.1016/j.diagmicrobio.2018.10.022

subject

Has Abstract

pub_date

2019-05-01 00:00:00

pages

38-40

issue

1

eissn

0732-8893

issn

1879-0070

pii

S0732-8893(18)30427-9

journal_volume

94

pub_type

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