Parasite load estimation by qPCR differentiates between asymptomatic and symptomatic infection in Indian visceral leishmaniasis.

Abstract:

:Using quantitative PCR (qPCR), we differentiated asymptomatic and symptomatic Indian Leishmania donovani infection. qPCR on blood of 40 visceral leishmaniasis, 130 endemic, and 40 non-endemic healthy controls showed 500 times less (P < .0001) parasitemia in asymptomatic compared to the symptomatic ones and threshold of 5 parasite genome/mL for the clinical disease.

authors

Sudarshan M,Sundar S

doi

10.1016/j.diagmicrobio.2014.01.031

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

40-2

issue

1

eissn

0732-8893

issn

1879-0070

pii

S0732-8893(14)00106-0

journal_volume

80

pub_type

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