当前位置： SCI文献检索 > DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE期刊下所有文献 > Reproducibility of positive results for rare pathogens on the FilmArray GI Panel.

Reproducibility of positive results for rare pathogens on the FilmArray GI Panel.

Abstract：

:Though the FilmArray GI Panel has a reported aggregate specificity and reproducibility of >97% and > 99%, respectively, the reproducibility is less understood in clinical practice. We measured the reproducibility of positive results for low-prevalence pathogens. Samples with positive results for selected targets were repeated using a different FilmArray module. Overall, 331 of 373 (89%) results were reproducible. Giardia lamblia (57/57, 100%), Cryptosporidium spp. (61/63, 97%), Cyclospora cayetanensis (34/35, 97%), Plesiomonas shigelloides (17/18, 94%), and Rotavirus A (76/77, 99%) were highly reproducible, while Adenovirus F40/41 (38/54, 70%), Vibrio spp. (8/10, 80%), V. cholerae (3/8, 37.5%), and Yersinia enterocolitica (36/50, 72%) were poorly reproducible. Review of 38 patients with nonreproducible results showed that 19 (50%) had evidence of gastroenteritis and only 6 (16%) had possible infection with the organism that showed a nonreproducible result. Higher false-positive rates with certain targets on FAGP emphasize the need for diagnostic stewardship.

journal_name

Diagn Microbiol Infect Dis

journal_title

Diagnostic microbiology and infectious disease

authors

Hitchcock MM,Hogan CA,Budvytiene I,Banaei N

doi

10.1016/j.diagmicrobio.2019.03.013

subject

Has Abstract

pub_date

2019-09-01 00:00:00

pages

10-14

issue

1

eissn

0732-8893

issn

1879-0070

pii

S0732-8893(19)30086-0

journal_volume

95

pub_type

杂志文章

相关文献

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE文献大全
  • Direct identification and antimicrobial susceptibility testing of microorganisms from positive blood cultures following isolation by lysis-centrifugation.

    abstract：:We evaluated a direct from positive blood culture pelleting procedure that utilizes a lysis-centrifugation protocol for the identification of microorganisms by MALDI-TOF MS with subsequent antimicrobial susceptibility testing (AST) and rapid methicillin- and beta-lactam-resistance screening. The identification evaluat...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2018.06.010

    authors： Campigotto A,Goneau L,Matukas LM

    更新日期：2018-11-01 00:00:00

  • Evaluation of the fully automated AIX1000 rapid plasma reagin system compared to a manual plasma reagin testing method for the diagnosis of syphilis.

    abstract：:The analytical performance of the FDA-cleared AIX1000 automated RPR testing platform was evaluated in comparison to manual RPR card testing. Eight hundred thirty-three patient serum samples were analyzed, 87 samples were positive by the AIX1000, 108 were positive by the manual test method; overall agreement between me...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2020.115081

    authors： Pyden A,Kang AD,Amato S,Dutta S,Berg G,Riedel S

    更新日期：2020-08-01 00:00:00

  • Detection of stx1, stx2, and eae genes of enterohemorrhagic Escherichia coli using SYBR Green in a real-time polymerase chain reaction.

    abstract：:We report a multiplex real-time polymerase chain reaction method for detecting enterohemorrhagic Escherichia coli (EHEC) from strains or stool specimens. This assay detected the virulence genes stx1, stx2, and eae, without the use of probes. The method, which was validated on a collection of 143 EHEC strains, is simpl...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2009.01.031

    authors： Chassagne L,Pradel N,Robin F,Livrelli V,Bonnet R,Delmas J

    更新日期：2009-05-01 00:00:00

  • Phaeomycotic cysts caused by Phoma species.

    abstract：:Phoma species are primarily phytopathogens which have been reported to sporadically cause human disease. We report a patient with phaeohyphomycotic cysts caused by Phoma species, which were initially mistaken for ganglions. ...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2011.04.009

    authors： Vasoo S,Yong LK,Sultania-Dudani P,Scorza ML,Sekosan M,Beavis KG,Huhn GD

    更新日期：2011-08-01 00:00:00

  • Superantigen profiling of Staphylococcus aureus infective endocarditis isolates.

    abstract：:The frequency of superantigen production among Staphylococcus aureus isolates associated with endocarditis is not well defined. We tested 154 S. aureus isolates from definite infective endocarditis cases for the presence of staphylococcal enterotoxins A-E, H, and TSST-1 by PCR, enzyme-linked immunosorbent assay, and u...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2014.03.009

    authors： Chung JW,Karau MJ,Greenwood-Quaintance KE,Ballard AD,Tilahun A,Khaleghi SR,David CS,Patel R,Rajagopalan G

    更新日期：2014-06-01 00:00:00

  • Cross-reactive monoclonal antibodies raised against the lipopolysaccharide antigen of Salmonella minnesota Re chemotype: diagnostic relevance.

    abstract：:Three cross-reactive monoclonal antibodies (MAbs) of IgM and IgG2b isotype were generated in two separate fusions after immunization of BALB/c mice with heat killed Salmonella minnesota R595 of Re chemotype and acid-treated bacteria, coated with Re lipopolysaccharide (LPS) antigen. The specificity of the MAbs was demo...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/s0732-8893(02)00545-x

    authors： Mitov I,Haralambieva I,Petrov D,Ivanova R,Kamarinchev B,Iankov I

    更新日期：2003-04-01 00:00:00

  • Epidemiology and outcome of multiple-species candidemia at a tertiary care center between 2004 and 2007.

    abstract：:The incidence of multiple-species candidemia (MSC) among cases of candidemia ranges between 2.8% and 8.0%. We sought to study the epidemiology and outcome of MSC at a tertiary care center. A retrospective analysis of MSC episodes occurring between 2004 and 2007 was performed. MSC was defined as > or =2 different Candi...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2009.03.010

    authors： Nace HL,Horn D,Neofytos D

    更新日期：2009-07-01 00:00:00

  • The distribution and drug susceptibilities of clinical Candida species in TSARY 2014.

    abstract：:The species distribution and drug susceptibilities of 1106 Candida isolates collected in Taiwan Surveillance of Antimicrobial Resistance of Yeasts (TSARY) in 2014 were determined. Candida albicans is still the dominant species, accounting for 35.9%, followed by 28.3% C. glabrata, 26.6% C. tropicalis, 5.2% C. parapsilo...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.diagmicrobio.2016.09.009

    authors： Zhou ZL,Lin CC,Chu WL,Yang YL,Lo HJ,TSARY Hospitals.

    更新日期：2016-12-01 00:00:00

  • Comparison of minimum inhibitory concentration results for gepotidacin obtained using agar dilution and broth microdilution methods.

    abstract：:Gepotidacin (GSK2140944) is a first in class, novel triazaacenaphthylene bacterial type II topoisomerase inhibitor in Phase 3 clinical development for the treatment of gonorrhea and uncomplicated urinary tract infections (acute cystitis). This study tested the equivalency of minimal inhibitory concentrations (MICs) ob...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2020.115107

    authors： Arends SJR,Canino MA,Mendes R,Scangarella-Oman NE,Flamm RK

    更新日期：2020-10-01 00:00:00

  • In vitro activity of linezolid as assessed through the 2013 LEADER surveillance program.

    abstract：:The 2013 LEADER surveillance program monitored the in vitro activity of linezolid and comparator agents against Gram-positive bacteria at 60 medical centers in the United States. A total of 7183 pathogens were contributed from 6 predetermined pathogen groups. The groups were Staphylococcus aureus, coagulase-negative s...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2014.12.009

    authors： Flamm RK,Mendes RE,Hogan PA,Ross JE,Farrell DJ,Jones RN

    更新日期：2015-04-01 00:00:00

  • Pharmacodynamics of tobramycin in patients with cystic fibrosis.

    abstract：:Relationships between pharmacodynamic indices (PI), such as the area under the concentration-time curve (AUC)/MIC ratio and time > MIC (T(>MIC)), and efficacy have been described for antimicrobial drugs. The use of these quantitative relationships may increase the power to demonstrate significant effects of drugs, obv...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2005.02.011

    authors： Mouton JW,Jacobs N,Tiddens H,Horrevorts AM

    更新日期：2005-06-01 00:00:00

  • Direct detection and amplification of Helicobacter pylori ribosomal 16S gene segments from gastric endoscopic biopsies.

    abstract：:Helicobacter pylori is an organism thought to play an important causative role in gastritis and peptic ulcer diseases. We have designed an RNA dot blot assay for the detection of H. pylori, using as probe a synthetic oligonucleotide complementary to its 16S rRNA. We have also used oligonucleotide primers, complementar...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/0732-8893(90)90079-b

    authors： Hoshina S,Kahn SM,Jiang W,Green PH,Neu HC,Chin N,Morotomi M,LoGerfo P,Weinstein IB

    更新日期：1990-11-01 00:00:00

  • In vitro activity of cefoperazone/sulbactam and other antimicrobials against anaerobic bacteria.

    abstract：:Sulbactam inhibits the hydrolytic activity of several, clinically important beta-lactamases including those produced by anaerobic bacteria. This study was undertaken to determine the effect of sulbactam on the activity of cefoperazone against 250 anaerobic bacteria including 174 isolates belonging to the Bacteroides f...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/0732-8893(90)90054-y

    authors： D'Amato RF,Hochstein L,Frankel H

    更新日期：1990-01-01 00:00:00

  • Impact of immune status on the clinical characteristics and treatment outcomes of nocardiosis.

    abstract：:Nocardiosis occurs in both immunocompromised and immunocompetent patients. We aimed to assess how its characteristics differ depending on patients' immune status. Of a total of 54 patients with culture-proven nocardiosis diagnosed over 13 years, 18 (33%) were immunocompetent. Half of immunocompetent patients had chron...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2016.05.004

    authors： Kim YK,Sung H,Jung J,Yu SN,Lee JY,Kim SH,Choi SH,Kim YS,Woo JH,Lee SO,Chong YP

    更新日期：2016-08-01 00:00:00

  • Mycobacterium avium: a pathogen of patients with acquired immunodeficiency syndrome.

    abstract：:Mycobacterium avium complex has been isolated with increasing frequency from humans during the last few decades. Thirteen patients admitted to the UCLA Medical Center with the diagnosis of acquired immunodeficiency syndrome (AIDS), in addition to having Kaposi's sarcoma, Pneumocystis pneumonia, and other opportunistic...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/0732-8893(84)90033-6

    authors： Berlin OG,Zakowski P,Bruckner DA,Clancy MN,Johnson BL Jr

    更新日期：1984-06-01 00:00:00

  • Methicillin-resistant Staphylococcus aureus with reduced susceptibility to vancomycin in Canada.

    abstract：:This study defines the characteristics of decreasing vancomycin susceptibility in multiple isolates of methicillin-resistant Staphylococcus aureus (MRSA) recovered from a hospitalized patient in Canada over a period of 6 months. The MICs of the isolates increased during therapy with vancomycin. The patient fractured h...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2006.07.007

    authors： Webster D,Rennie RP,Brosnikoff CL,Chui L,Brown C

    更新日期：2007-02-01 00:00:00

  • Molecular epidemiology of carbapenem-resistant Pseudomonas aeruginosa carrying metallo-beta-lactamase genes in Taiwan.

    abstract：:Seventy-two isolates of carbapenem-resistant Pseudomonas aeruginosa (CRPA) collected through the Taiwan Surveillance of Antimicrobial Resistance (TSAR) program in 2000 and 2002 were studied for carriage of metallo-beta-lactamase (MBL), integrase genes, and integrons. Epidemiologic relatedness was determined using puls...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2007.01.009

    authors： Huang YT,Chang SC,Lauderdale TL,Yang AJ,Wang JT

    更新日期：2007-10-01 00:00:00

  • Epidemiologic typing of multiply drug-resistant Pseudomonas aeruginosa isolated from an outbreak in an intensive care unit.

    abstract：:From June to August 1991, there was an outbreak of Pseudomonas aeruginosa infections in an intensive care unit in a general hospital in Sao Paulo, Brazil. We obtained 14 isolates from 14 patients, 11 from tracheal aspirate, and 3 from surgical wound exudates. These strains were typed by serotyping, pyocin typing, and ...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/0732-8893(93)90063-d

    authors： Sader HS,Pignatari AC,Leme IL,Burattini MN,Tancresi R,Hollis RJ,Jones RN

    更新日期：1993-07-01 00:00:00

  • Molecular types and antimicrobial susceptibility patterns of Clostridium difficile isolates in different epidemiological settings in a tertiary care center in Israel.

    abstract：:The aims of this prospective study were to examine the correlation between the molecular types and the antimicrobial susceptibility patterns of Clostridium difficile isolates with the source of acquisition and the occurrence of C. difficile infections (CDI) in a tertiary center in Israel. All available isolates from c...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2016.08.021

    authors： Miller-Roll T,Na'amnih W,Cohen D,Carmeli Y,Adler A

    更新日期：2016-12-01 00:00:00

  • Characterization of novel Mycobacterium tuberculosis pncA gene mutations in clinical isolates from the Ukraine.

    abstract：:Multidrug-resistant (MDR) and extensively drug-resistant (XDR) Mycobacterium tuberculosis cases in the Ukraine are increasing. Pyrazinamide (PZA) is critically important for first- and second-line tuberculosis (TB) treatment regimes. However, PZA drug susceptibility testing is time consuming and technically challengin...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2018.10.018

    authors： Daum LT,Konstantynovska OS,Solodiankin OS,Poteiko PI,Bolotin VI,Rodriguez JD,Gerilovych AP,Chambers JP,Fischer GW

    更新日期：2019-04-01 00:00:00

  • Optimal cefotaxime dosing for gram-negative bacteremia: effective trough serum bactericidal titers and drug concentrations 8 and 12 hr after 1- or 2-gm infusions.

    abstract：:Thirteen adult patients (47-81 yr) with gram-negative bacteremia and normal (less than or equal to 1.5 mg/dl) serum creatinines were treated with 1 or 2 gm of cefotaxime every 8 or 12 hr. The infecting organisms were Escherichia coli (9 strains), Klebsiella pneumoniae (2 strains), and one isolate of Salmonella enterit...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/0732-8893(88)90102-2

    authors： Goodpasture HC,Gerlach EH,Jones RN,Peterie JD

    更新日期：1988-02-01 00:00:00

  • A two year global evaluation of the susceptibility of Candida species to fluconazole by disk diffusion.

    abstract：:The in-vitro activity of fluconazole against 46,831 yeast isolates collected over a two-year period from 57 laboratories in 33 countries worldwide was assessed using a disc diffusion method. Candida albicans was the organism isolated most frequently, accounting for 68.6% of the total number of isolates. C. glabrata, C...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/s0732-8893(01)00243-7

    authors： Liebowitz LD,Ashbee HR,Evans EG,Chong Y,Mallatova N,Zaidi M,Gibbs D,Global Antifungal Surveillance Group.

    更新日期：2001-05-01 00:00:00

  • Elution kinetics, antimicrobial activity, and mechanical properties of 11 different antibiotic loaded acrylic bone cement.

    abstract：:Antibiotic-loaded acrylic bone cements (ALABC) spacers are routinely used in the treatment of prosthetic joint infections. The objectives of our study were to evaluate different ALABC for elution kinetics, thermal stability, and mechanical properties. A 10 or 20% mixture (w/w) beads of medium viscosity bone cement (De...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2013.09.014

    authors： Gálvez-López R,Peña-Monje A,Antelo-Lorenzo R,Guardia-Olmedo J,Moliz J,Hernández-Quero J,Parra-Ruiz J

    更新日期：2014-01-01 00:00:00

  • Detection of Clostridium difficile toxins A, B and binary toxin with slow off-rate modified aptamers.

    abstract：:Rapid and accurate diagnostic tests for Clostridium difficile infections (CDI) are crucial for management of patients with suspected CDI and for infection control. Enzyme immunoassays for detection of the toxins are routinely used but lack adequate sensitivity. We generated slow off-rate modified aptamers (SOMAmer™ re...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2013.03.029

    authors： Ochsner UA,Katilius E,Janjic N

    更新日期：2013-07-01 00:00:00

  • Insufficient diagnostic accuracy of imported serological kits for Helicobacter pylori infection in Japanese population.

    abstract：:Although there are many reports of the high diagnostic accuracy of commercially available serologic kits for Helicobacter pylori infection in Western countries, they rarely has been investigated in oriental population. Accordingly we examined their usefulness in 492 Japanese patients with dyspeptic symptoms. Diagnosti...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0732-8893(99)00143-1

    authors： Miwa H,Kikuchi S,Ohtaka K,Kobayashi O,Ogihara A,Hojo M,Nagahara A,Sato N

    更新日期：2000-02-01 00:00:00

  • Emergence of metallo-β-lactamases in Enterobacteriaceae from Argentina.

    abstract：:Carbapenem susceptibility in Enterobacteriaceae (M9921, M9959) revealed the presence of MBLs bla(VIM-2) (M9959) and bla(IMP-8) (M9921), both as first cassettes of class-1-integrons. ESBL bla(PER-2) was detected in both strains and M9921 also harboured qnrB10, aac(6')-Ib and aac(6')-Ib-cr. This is the first report of M...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2010.08.025

    authors： Gomez S,Rapoport M,Togneri A,Viegas-Caetano J,Faccone D,Corso A,Petroni A,Pasteran F

    更新日期：2011-01-01 00:00:00

  • Improvement of a latex agglutination test for the evaluation of oxacillin resistance in coagulase-negative staphylococci.

    abstract：:The "Slidex MRSA Detection" test (Denka Seiken, Japan) is a latex agglutination assay able to detect PBP2a. We evaluated its ability to differentiate mecA-positive from mecA-negative coagulase-negative staphylococci. We included 100 coagulase-negative staphylococci clinical isolates belonging to 9 species, 54 mecA pos...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2004.06.005

    authors： Corso A,Soloaga R,Faccone D,Gagetti P,Corbella S,Iglesias M,Galas M

    更新日期：2004-11-01 00:00:00

  • Natural antimicrobial susceptibility patterns and biochemical identification of Escherichia albertii and Hafnia alvei strains.

    abstract：:Bangladeshi diarrheagenic Hafnia alvei-like strains have been described recently as the new species Escherichia albertii (Int J Syst Evolut Microbiol. 2003;53:807-810). The natural susceptibility of 21 E. albertii and 76 H. alvei strains to 69 antimicrobial agents was examined, applying a microdilution procedure in Is...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2004.10.008

    authors： Stock I,Rahman M,Sherwood KJ,Wiedemann B

    更新日期：2005-03-01 00:00:00

  • Evaluation of the efficacy of a posaconazole and anidulafungin combination in a murine model of pulmonary aspergillosis due to infection with Aspergillus fumigatus.

    abstract：:Posaconazole (PSC) in combination with anidulafungin (AFG) was evaluated in a murine model of pulmonary aspergillosis. Immunosuppressed animals were infected via the nasal cavity with 2 different A. fumigatus strains. The animals received PSC (oral, 20mg/kg per day) and/or AFG (i.p., 10mg/kg per day) for 7days. On Day...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2017.10.004

    authors： Bedin Denardi L,Pantella Kunz de Jesus F,Keller JT,Weiblen C,de Azevedo MI,Oliveira V,Morais Santurio J,Hartz Alves S

    更新日期：2018-01-01 00:00:00

  • Detection of beta-lactamase-negative ampicillin resistance in Haemophilus influenzae in Belgium.

    abstract：:Haemophilus influenzae, a frequent colonizer of the respiratory tract, is the causative agent of several clinically important infections. In cases that require therapeutic intervention, laboratory susceptibility testing can detect beta-lactam antibiotic resistance and guide the best treatment course. In the absence of...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2018.10.009

    authors： Schotte L,Wautier M,Martiny D,Piérard D,Depypere M

    更新日期：2019-03-01 00:00:00