abstract：:We have previously reported that the deletion of BMAL1 gene has opposite effects in respect to its contribution to the pathways that are effective in the multistage carcinogenesis process. BMAL1 deletion sensitized nearly normal breast epithelial (MCF10A) and invasive breast cancer cells (MDA-MB-231) to cisplatin- and...

journal_title：Functional & integrative genomics

authors： Emisoglu-Kulahli H,Gul S,Morgil H,Ozcan O,Aygenli F,Selvi S,Kavakli IH,Ozturk N

更新日期：2021-01-01 00:00:00

abstract：:Seasonal estrus is a key factor limiting animal fertility, and understanding the molecular mechanisms that regulate animal estrus is important for improving animal fertility. The pituitary gland, which is the most important endocrine gland in mammals, plays an important role in regulating the physiological processes s...

journal_title：Functional & integrative genomics

authors： Li X,Li C,Xu Y,Yao R,Li H,Ni W,Quan R,Zhang M,Liu L,Yu S,Ullah Y,Hu R,Li Y,Guo T,Wang X,Hu S

更新日期：2020-07-01 00:00:00

abstract：:Abiotic stress tolerance is a complex trait regulated by multiple genes and gene networks in plants. A range of abiotic stresses are known to limit rice productivity. Meta-transcriptomics has emerged as a powerful approach to decipher stress-associated molecular network in model crops. However, retaining specificity o...

journal_title：Functional & integrative genomics

authors： Smita S,Katiyar A,Lenka SK,Dalal M,Kumar A,Mahtha SK,Yadav G,Chinnusamy V,Pandey DM,Bansal KC

更新日期：2020-01-01 00:00:00

abstract：:Although the economic value of wheat flour is determined by the complement of gluten proteins, these proteins have been challenging to study because of the complexity of the major protein groups and the tremendous sequence diversity among wheat cultivars. The completion of a high-quality wheat genome sequence from the...

journal_title：Functional & integrative genomics

authors： Altenbach SB,Chang HC,Simon-Buss A,Mohr T,Huo N,Gu YQ

更新日期：2020-01-01 00:00:00

abstract：:The ever-rising population of the twenty-first century together with the prevailing challenges, such as deteriorating quality of arable land and water, has placed a big challenge for plant breeders to satisfy human needs for food under erratic weather patterns. Rice, wheat, and maize are the major staple crops consume...

journal_title：Functional & integrative genomics

authors： Choudhary M,Wani SH,Kumar P,Bagaria PK,Rakshit S,Roorkiwal M,Varshney RK

更新日期：2019-09-01 00:00:00

abstract：:Rhizoctonia solani AG1-IA is a soil-borne necrotrophic pathogen that causes devastating rice sheath blight disease in rice-growing regions worldwide. Sclerotia play an important role in the life cycle of R. solani AG1-IA. In this study, RNA sequencing was used to investigate the transcriptomic dynamics of sclerotial d...

journal_title：Functional & integrative genomics

authors： Shu C,Zhao M,Anderson JP,Garg G,Singh KB,Zheng W,Wang C,Yang M,Zhou E

更新日期：2019-09-01 00:00:00

abstract：:Water temperature affects the survival, growth, immunity, reproduction, and productivity of farmed fish. The temperature beyond suitable range will disrupt the normal physiological activity. Common carp (Cyprinus carpio L.) is a representative eurythermic fish; they are able to sense and respond to changes in water te...

journal_title：Functional & integrative genomics

authors： Sun J,Zhao L,Wu H,Lian W,Cui C,Du Z,Luo W,Li M,Yang S

更新日期：2019-03-01 00:00:00

abstract：:GDSL-type esterase/lipase (GELP) is mainly characterized by a conserved GDSL domain at N terminus, and is widely found in all living species, both prokaryotes and eukaryotes. GELP gene family consists of a wide range of members playing important roles in plant physiological processes, such as development, stress respo...

journal_title：Functional & integrative genomics

authors： Cao Y,Han Y,Meng D,Abdullah M,Yu J,Li D,Jin Q,Lin Y,Cai Y

更新日期：2018-11-01 00:00:00

abstract：:In grapes (Vitis vinifera L.), exogenous gibberellic acid (GA3) is applied at different stages of bunch development to achieve desirable bunch shape and berry size in seedless grapes used for table purpose. RNA sequence-based transcriptome analysis was used to understand the mechanism of GA3 action at cluster emergenc...

journal_title：Functional & integrative genomics

authors： Upadhyay A,Maske S,Jogaiah S,Kadoo NY,Gupta VS

更新日期：2018-07-01 00:00:00

abstract：:Cotton (Gossypium spp.) is an imperative economic crop of the globe due to its natural textile fiber. Molecular mechanisms of fiber development have been greatly revealed in allotetraploid cotton but remained unexplored in Gossypium herbaceum. G. herbaceum can withstand the rigors of nature like drought and pests but ...

journal_title：Functional & integrative genomics

authors： Parekh MJ,Kumar S,Fougat RS,Zala HN,Pandit RJ

更新日期：2018-03-01 00:00:00

abstract：:Drought is a major abiotic stress affecting crop productivity and quality. As a class of noncoding RNA, microRNA (miRNA) plays important roles in plant growth, development, and stress response. However, their response and roles in tomato drought stress is largely unknown. Here, by using high-throughput sequencing, we ...

journal_title：Functional & integrative genomics

authors： Liu M,Yu H,Zhao G,Huang Q,Lu Y,Ouyang B

更新日期：2018-01-01 00:00:00

abstract：:The aim of this study was to examine the effect of abscisic acid (ABA), sucrose, and auxin on grape fruit development and to assess the mechanism of these three factors on the grape fruit ripening process. Different concentrations of ABA, sucrose, and auxin were used to treat the grape fruit, and the ripening-related ...

journal_title：Functional & integrative genomics

authors： Jia H,Xie Z,Wang C,Shangguan L,Qian N,Cui M,Liu Z,Zheng T,Wang M,Fang J

更新日期：2017-07-01 00:00:00

abstract：:Aldo/keto reductases (AKRs) constitute a multitasking protein family that catalyzes diverse metabolic transformations including detoxification of stress generated reactive aldehydes. Yet this important protein family is poorly understood particularly in cyanobacteria, the ecologically most diverse and significant grou...

journal_title：Functional & integrative genomics

authors： Agrawal C,Yadav S,Rai S,Chatterjee A,Sen S,Rai R,Rai LC

更新日期：2017-07-01 00:00:00

abstract：:The proneness of diseases and susceptibility towards drugs vary from person to person. At present, there is a strong demand for the personalization of drugs. The genetic signature behind proneness of the disease has been studied through a comprehensive 'octopodial approach'. All the genetic variants included in the ap...

journal_title：Functional & integrative genomics

authors： Iyer PM,Karthikeyan S,Sanjay Kumar P,Krishnan Namboori PK

更新日期：2017-07-01 00:00:00

abstract：:MicroRNAs (miRNAs) are small RNAs (sRNAs) that regulate gene expression in development and adaptive responses to the environment. The early days in the sRNA field was one of the most exciting and promising moments in modern biology, attracting large investments to the understanding of the underlining mechanisms and th...

journal_title：Functional & integrative genomics

authors： Reis RS

更新日期：2017-05-01 00:00:00

abstract：:Campylobacter jejuni remains a major cause of human gastroenteritis with estimated annual incidence rate of 450 million infections worldwide. C. jejuni is a major burden to public health in both socioeconomically developing and industrialized nations. Virulence determinants involved in C. jejuni pathogenesis are multi...

journal_title：Functional & integrative genomics

authors： Mehla K,Ramana J

更新日期：2017-01-01 00:00:00

abstract：:Medicago sativa L. (alfalfa) 'Zhaodong' is an important forage legume that can safely survive in northern China where winter temperatures reach as low as -30 °C. Survival of alfalfa following freezing stress depends on the amount and revival ability of crown buds. In order to investigate the molecular mechanisms of fr...

journal_title：Functional & integrative genomics

authors： Song L,Jiang L,Chen Y,Shu Y,Bai Y,Guo C

更新日期：2016-09-01 00:00:00

abstract：:GRAS domain genes are a group of important plant-specific transcription factors that have been reported to be involved in plant development. In order to know the roles of GRAS genes in grapevine, a widely cultivated fruit crop, the study on grapevine GRAS (VvGRAS) was carried out, and from which, 43 were identified fr...

journal_title：Functional & integrative genomics

authors： Sun X,Xie Z,Zhang C,Mu Q,Wu W,Wang B,Fang J

更新日期：2016-07-01 00:00:00

abstract：:The root-knot nematode Meloidogyne incognita is among the most damaging plant-parasitic pests of several crops including cotton (Gossypium hirsutum) and tomato (Lycopersicon escultentum). Recently, a genome has become available for M. incognita, which greatly facilitates investigation of the interactions between M. in...

journal_title：Functional & integrative genomics

authors： Zhang Y,Wang Y,Xie F,Li C,Zhang B,Nichols RL,Pan X

更新日期：2016-03-01 00:00:00

abstract：:Tuber mustard (Brassica juncea (L.) Czern. et Coss. var. tumida Tsen et Lee) is an important vegetable crop with a characteristic of expanded stem that is edible. The underlying molecular mechanism of the stem expansion is not well understood. Here, we reported that a total of 51 differentially expressed fragments (DE...

journal_title：Functional & integrative genomics

authors： Cao L,Liu B,Li J,Yu N,Zou X,Chen L

更新日期：2015-11-01 00:00:00

abstract：:MicroRNAs, small regulatory molecules with significant impacts on the transcriptional network of all living organisms, have been the focus of several studies conducted mostly on modern wheat cultivars. In this study, we investigated miRNA repertoires of modern durum wheat and its wild relatives, with differing degrees...

journal_title：Functional & integrative genomics

authors： Akpinar BA,Kantar M,Budak H

更新日期：2015-09-01 00:00:00

abstract：:Auxin response factors (ARFs) are recently discovered transcription factors that bind with auxin response elements (AuxRE, TGTCTC) to regulate the expression of early auxin-responsive genes. To our knowledge, the ARF gene family has never been characterized in cotton, the most important fiber crop in the world. In thi...

journal_title：Functional & integrative genomics

authors： Sun R,Wang K,Guo T,Jones DC,Cobb J,Zhang B,Wang Q

更新日期：2015-07-01 00:00:00

abstract：:Culex pipiens mosquitoes are important disease vectors inhabiting temperate zones, worldwide. The seasonal reduction in temperature and photoperiod accompanying late summer and early fall prompts female mosquitoes to enter diapause, a stage of developmental arrest and physiological conditioning that enhances survival ...

journal_title：Functional & integrative genomics

authors： Hickner PV,Mori A,Zeng E,Tan JC,Severson DW

更新日期：2015-07-01 00:00:00

abstract：:Natural selection drives species adaptations to biotic and abiotic stresses. Species distributed along a moisture gradient, such as Stipa purpurea, a dominant grass in alpine arid and semi-arid meadows on the Tibetan Plateau, provide an opportunity to evaluate the effects of long-term adaptation to differing degrees o...

journal_title：Functional & integrative genomics

authors： Yang Y,Li X,Kong X,Ma L,Hu X,Yang Y

更新日期：2015-05-01 00:00:00

abstract：:In silico analysis together with cloning, molecular characterization and heterologous expression reports that the hypothetical protein All5371 of Anabaena sp. PCC7120 is a novel hydroperoxide scavenging protein similar to AhpD of bacteria. The presence of E(X)11CX HC(X)3H motif in All5371 confers peroxidase activity a...

journal_title：Functional & integrative genomics

authors： Shrivastava AK,Singh S,Singh PK,Pandey S,Rai LC

更新日期：2015-01-01 00:00:00

abstract：:Jatropha curcas is a new promising bioenergy crop due to the high oil content in its seeds that can be converted into biodiesel. Seed size, a major determinant of Jatropha oil yield, is a target trait for Jatropha breeding. Due to the vital roles of phytohormone auxin in controlling seed and fruit development, we scre...

journal_title：Functional & integrative genomics

authors： Ye J,Liu P,Zhu C,Qu J,Wang X,Sun Y,Sun F,Jiang Y,Yue G,Wang C

更新日期：2014-12-01 00:00:00

abstract：:Fungal species are potential dye decomposers since these secrete spectra of extracellular enzymes involved in catabolism. However, cellular mechanisms underlying azo dye catalysis and detoxification are incompletely understood and obscure. A potential strain designated as Penicillium oxalicum SAR-3 demonstrated broad-...

journal_title：Functional & integrative genomics

authors： Saroj S,Kumar K,Prasad M,Singh RP

更新日期：2014-12-01 00:00:00

abstract：:Stem blister canker, caused by Botryosphaeria dothidea, is becoming the most serious disease of poplar in China. The molecular basis of the poplar in response to stem blister canker is not well understood. To reveal the global transcriptional changes of poplar to infection by B. dothidea, Solexa paired-end sequencing ...

journal_title：Functional & integrative genomics

authors： Liao W,Ji L,Wang J,Chen Z,Ye M,Ma H,An X

更新日期：2014-09-01 00:00:00

abstract：:MicroRNAs (miRNAs) play a pivotal role in post-transcriptional regulation of gene expression in plants. In this study, we investigate miRNAs in an agronomically important common tobacco in China, named Honghua Dajinyuan (a drought-tolerant cultivar). Here, we report a comprehensive analysis of miRNA expression profile...

journal_title：Functional & integrative genomics

authors： Yin F,Gao J,Liu M,Qin C,Zhang W,Yang A,Xia M,Zhang Z,Shen Y,Lin H,Luo C,Pan G

更新日期：2014-06-01 00:00:00

abstract：:Late blight is a serious economic threat to potato crop, sometimes leading to complete crop loss. The resistance in potato to late blight can be qualitative or quantitative in nature. Qualitative resistance is not durable. Though quantitative resistance is durable, the breeding is challenging due to polygenic inherita...

journal_title：Functional & integrative genomics

authors： Yogendra KN,Pushpa D,Mosa KA,Kushalappa AC,Murphy A,Mosquera T

更新日期：2014-06-01 00:00:00

abstract：:Gene order is largely collinear in the small-grained cereals, a feature which has proved helpful in both marker development and positional cloning. The accuracy of a virtual gene order map ("genome zipper") for barley (Hordeum vulgare), developed by combining a genetic map of this species with a large number of gene l...

journal_title：Functional & integrative genomics

authors： Poursarebani N,Ariyadasa R,Zhou R,Schulte D,Steuernagel B,Martis MM,Graner A,Schweizer P,Scholz U,Mayer K,Stein N

更新日期：2013-08-01 00:00:00

abstract：:Winter wheat lines can achieve cold acclimation (development of tolerance to freezing temperatures) and vernalization (delay in transition from vegetative to reproductive phase) in response to low non-freezing temperatures. To describe cold-acclimation-specific processes and pathways, we utilized cold acclimation tran...

journal_title：Functional & integrative genomics

authors： Karki A,Horvath DP,Sutton F

更新日期：2013-03-01 00:00:00

abstract：:Advances in our understanding of genome structure provide consistent evidence for the existence of a core genome representing species classically defined by phenotype, as well as conditionally dispensable components of the genome that shows extensive variation between individuals of a given species. Generally, conserv...

journal_title：Functional & integrative genomics

authors： Appels R,Barrero R,Bellgard M

更新日期：2013-03-01 00:00:00

abstract：:Nuclear genomes of human, animals, and plants are organized into subunits called chromosomes. When isolated into aqueous suspension, mitotic chromosomes can be classified using flow cytometry according to light scatter and fluorescence parameters. Chromosomes of interest can be purified by flow sorting if they can be ...

journal_title：Functional & integrative genomics

authors： Doležel J,Vrána J,Safář J,Bartoš J,Kubaláková M,Simková H

更新日期：2012-08-01 00:00:00

abstract：:The oomycete pathogen Plasmopara viticola (Berk. et Curt.) Berl. et de Toni is the causing agent of the destructive downy mildew disease in grapevine. Despite the advances towards elucidation of grapevine resistance mechanisms to downy mildew, increased knowledge of the biological and genetic components of the pathosy...

journal_title：Functional & integrative genomics

authors： Figueiredo A,Monteiro F,Fortes AM,Bonow-Rex M,Zyprian E,Sousa L,Pais MS

更新日期：2012-06-01 00:00:00

abstract：:Carefully analyzed expression profiles can serve as a valuable reference for deciphering gene functions. We exploited the potential of whole genome microarrays to measure the spatial and temporal expression profiles of rice genes in 19 stages of vegetative and reproductive development. We could verify expression of 22...

journal_title：Functional & integrative genomics

authors： Sharma R,Agarwal P,Ray S,Deveshwar P,Sharma P,Sharma N,Nijhawan A,Jain M,Singh AK,Singh VP,Khurana JP,Tyagi AK,Kapoor S

更新日期：2012-06-01 00:00:00

abstract：:Genomic structural variation is an important and abundant source of genetic and phenotypic variation. We previously reported an initial analysis of copy number variations (CNVs) in Angus cattle selected for resistance or susceptibility to gastrointestinal nematodes. In this study, we performed a large-scale analysis o...

journal_title：Functional & integrative genomics

authors： Hou Y,Liu GE,Bickhart DM,Matukumalli LK,Li C,Song J,Gasbarre LC,Van Tassell CP,Sonstegard TS

更新日期：2012-03-01 00:00:00

abstract：:Bread wheat (Triticum aestivum L.) is one of the most important crops globally and a high priority for genetic improvement, but its large and complex genome has been seen as intractable to whole genome sequencing. Isolation of individual wheat chromosome arms has facilitated large-scale sequence analyses. However, so ...

journal_title：Functional & integrative genomics

authors： Lucas SJ,Šimková H,Šafář J,Jurman I,Cattonaro F,Vautrin S,Bellec A,Berges H,Doležel J,Budak H

更新日期：2012-03-01 00:00:00

abstract：:Gastrointestinal nematodes of the genus Cooperia are arguably the most important parasites of cattle. The bovine jejunal transcriptome was characterized in response to Cooperia oncophora infection using RNA-seq technology. Approximately 71% of the 25,670 bovine genes were detected in the jejunal transcriptome. However...

journal_title：Functional & integrative genomics

authors： Li RW,Schroeder SG

更新日期：2012-03-01 00:00:00

abstract：:The assembly of a 1.3-Mb size region of the wheat genome has provided the opportunity to study a recent nuclear mitochondrial DNA insertion (NUMT). In the present study, we have studied two bacterial artificial chromosomes (BACs) and characterized a 52-kb NUMT segment from the tetraploid and hexaploid wheat BAC librar...

journal_title：Functional & integrative genomics

authors： Zhang J,Jia J,Breen J,Kong X

更新日期：2011-12-01 00:00:00