解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Novel coronavirus disease 2019 (COVID-19) is a positive-sense single-stranded RNA virus which belongs to the Coronaviridae family. COVID-19 outbreak became evident after the severe acute respiratory syndrome coronavirus and the Middle East respiratory syndrome coronavirus in the twenty-first century as the start of th...
journal_title:3 Biotech
pub_type: 杂志文章,评审
doi:10.1007/s13205-021-02657-3
更新日期:2021-02-01 00:00:00
abstract::The emerging SARS-CoV-2 viral disease (COVID-19) has caused a global health alert due to its high rate of infection and mortality in individuals with chronic cardiovascular comorbidities, in addition to generating complex clinical conditions. This has forced the scientific community to explore different strategies tha...
journal_title:3 Biotech
pub_type: 杂志文章,评审
doi:10.1007/s13205-020-02619-1
更新日期:2021-02-01 00:00:00
abstract::Together with their undeniable role in the ecology of arid and semiarid ecosystems, Agave species are emerging as a model to dissect the relationships between crassulacean acid metabolism and high efficiency of light and water use, and as an energy crop for bioethanol production. Transcriptome resources from economica...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02620-8
更新日期:2021-02-01 00:00:00
abstract::In this investigation, potential inhibitors of α-amylase, one of the key regulatory enzymes in diabetes were characterized from the methanolic extract of Leucas ciliata Benth. (Lamiaceae), a traditional medicinal plant of the Western Ghats, southern India and the ethyl acetate extract of Streptomyces longisporoflavus ...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02547-0
更新日期:2021-02-01 00:00:00
abstract::Somatic embryogenesis is an important and wonderful biotechnological tool used to develop whole plant from a single or a group of somatic cells. The differentiated somatic cells become totipotent stem cells by drastic reprogramming of a wide range of cellular activities, leading to the acquisition of embryogenic compe...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-021-02649-3
更新日期:2021-02-01 00:00:00
abstract::Emblica officinalis Gaertn. syn. Phyllanthus emblica L., universally known as 'Amla' or 'Aonla' or 'Indian gooseberry', is a popular fruit tree belonging to the family Euphorbiaceae and order Geraniales. It is said to be the very first tree that originated on earth, as claimed by age-old Indian mythology. Almost all p...
journal_title:3 Biotech
pub_type: 杂志文章,评审
doi:10.1007/s13205-020-02615-5
更新日期:2021-02-01 00:00:00
abstract::Pseudozyma sp. are yeasts that are commercially important due to their production of glycolipid biosurfactants, squalene, itaconic acid, and exopolysaccharide. The search for other analgesia inducing drugs, such as opiates and non-steroidal anti-inflammatory drugs (NSAIDs), as alternatives is beneficial. In this study...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02635-1
更新日期:2021-02-01 00:00:00
abstract::Bio-inoculants play an important role for sustainable agriculture. Application of nanocompounds in the agriculture sector provides strength and is reported to enhance crop production but the combined effect of nanocompounds and plant growth-promoting rhizobacteria on plants has not been studied much. Therefore, the pr...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02561-2
更新日期:2021-01-01 00:00:00
abstract::This study aimed to explore the effect of Dendrobium officinale (DO) on the diversity of intestinal mucosal flora in high-fat diet mice and provided an experimental basis for the development and research of DO and its series products. Twenty-four mice were randomly assigned to four equal groups of six mice, namely the...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02558-x
更新日期:2021-01-01 00:00:00
abstract::This study was aimed at investigating the phytochemical constituents, antifungal properties and antibiotic-modifying activity of the aqueous crude extract and fractions of Amburana cearensis seeds (CEFAC). The CEFAC were chemically characterized by LC-MS/MS-QTOF. In addition, the antifungal activity was assayed by the...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02551-4
更新日期:2020-12-01 00:00:00
abstract::In the present study, we investigated radiation mitigating activities of Psidium guajava L. (P. guajava) against whole-body X- ray induced damages in albino Wistar rat model. The animals were orally administered with 200 mg/kg bodyweight of hydroalcoholic leaf extract of P. guajava for five consecutive days and on the...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02484-y
更新日期:2020-12-01 00:00:00
abstract::In this study, analytical profiling of the bevacizumab (BVZ) biosimilars (N = 3) approved in India were evaluated for charge heterogeneity, isoelectric focusing, aggregation and in vitro potency analysis. The charge variants were characterized using high performance cation-exchange chromatography (CEX-HPLC), capillary...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02506-9
更新日期:2020-12-01 00:00:00
abstract::In the present study, the growth conditions and accumulation of ectoines (ectoine and hydroxyectoine) by Paludifilum halophilum DSM 102817T under salt stress conditions have been investigated. The productivity assay of this strain for ectoines revealed that the highest cellular content was reached in the minimal gluco...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02512-x
更新日期:2020-12-01 00:00:00
abstract::The study investigates the ability of methanolic extract of Andrographis paniculata (MAP) to supplement polyvalent anti-snake venom (ASV) in inhibiting neurotoxic enzyme acetylcholinesterase (AChE) and 'spreading factor' hyaluronidase from Naja naja (N.N) venom. AChE and hyaluronidase activity were measured in 100 or ...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02462-4
更新日期:2020-11-01 00:00:00
abstract::The Trichoderma harzianum l-methioninase was purified 7.15-fold with a recovery of 47.9% and the specific activity of 74.4 U/mg of protein. The purified enzyme has an apparent molecular mass of 48 kDa on SDS-PAGE and exhibited maximum activity at pH 8 and 35 °C. The enzyme was catalytically stable below 50 °C and at a...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02494-w
更新日期:2020-11-01 00:00:00
abstract::The wound healing process is characterized by varied biological and molecular cascades including inflammation, tissue proliferation, and remodeling phase. To augment and maintain these cascades, an all-natural matrix system is proposed. Biocompatible biopolymers, sodium alginate and gelatin, were employed to prepare m...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02453-5
更新日期:2020-11-01 00:00:00
abstract::Advancement in nanotechnology has improved ways for large-scale production and characterization of nanoparticles of physiologically important metals. The current study explores the impact of Zinc Oxide Nanoparticles (ZnO-NP) and Chitosan-Zinc oxide nano-bioformulation (CH-ZnO) in tissue culture raised callus of Nicoti...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02469-x
更新日期:2020-11-01 00:00:00
abstract::Paddy soils represent the largest anthropogenic wetlands on earth. Soil drying and rewetting that occurs annually inflict significant stress on soil microbial activities in paddy soils. An incubation experiment of 60 years of paddy soil was conducted to simulate the conditions of paddy fields (25 °C and 75% air humidi...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02486-w
更新日期:2020-11-01 00:00:00
abstract::Glycoprotein D (gD) of Herpes Simplex Virus-2 is used as an antigen in various anti-herpes subunit vaccines owing to its involvement in binding the host cell receptors for host infectivity. However, most of these monomeric protein based candidates have shown low immunogenicity in animal models. To enhance the immunoge...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02452-6
更新日期:2020-11-01 00:00:00
abstract::MicroRNAs-199a-5p (miR-199a-5p) plays critical regulatory roles in various types of human cancers. However, the biological function and regulatory mechanisms of miR-199a-5p in colorectal cancer (CRC) remain unclear. The aim of this study was to investigate the role of miR-199a-5p in CRC and possible mechanisms of its ...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02433-9
更新日期:2020-10-01 00:00:00
abstract::In the present work, bioethanol was produced by sugar fermentation obtained from water hyacinth using a novelty hybrid method composed of steam explosion and enzymatic hydrolysis, using hydrolytic enzymes produced by solid-state fermentation and water hyacinth as substrate. The highest activity, 42 U for xylanase and ...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02426-8
更新日期:2020-10-01 00:00:00
abstract::Adenosine triphosphate (ATP) is produced at the early stage of seed germination and provides the energy for metabolism. The source of ATP in seeds may be Perl's pathway, but this has not yet been confirmed. In this study, using germinating seeds of poplar as the experimental materials, the transcript levels of genes r...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02413-z
更新日期:2020-10-01 00:00:00
abstract::Today, the role of nanotechnology in human life is undeniable as a broad range of industries, particularly food and medicine sectors, have been dramatically influenced. Nanomaterials can contribute to food safety by forming new nano-sized ingredients with modified physicochemical characteristics. Nanotechnologies can ...
journal_title:3 Biotech
pub_type: 杂志文章,评审
doi:10.1007/s13205-020-02409-9
更新日期:2020-10-01 00:00:00
abstract::In the current study, aerial parts (leaves, stem and shoots) of C. album were extracted with methanol and subjected to phytochemical and HPLC analysis. Agar well diffusion method was used for anti-bacterial activity against Gram-negative strains Escherichia coli, Salmonella typhi, Klebsiella, Pseudomonas aeruginosa an...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02436-6
更新日期:2020-10-01 00:00:00
abstract::Antibiotic resistance is a global public health issue and it is even more daunting in developing countries. The main objective of present study was to investigate molecular responses of antibiotic-resistant bacteria. The 48 bacterial strains, which were previously isolated and identified were subjected to disc diffusi...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02366-3
更新日期:2020-09-01 00:00:00
abstract::The action of FTO on myoblasts proliferation and differentiation and molecular mechanism underlying it were investigated by transfecting with FTO lentiviral overexpression vector and gene expression profile sequencing. Compared with the control group, myoblasts with FTO transfection was significantly enhanced prolifer...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02386-z
更新日期:2020-09-01 00:00:00
abstract::In the present study, modified solvent evaporation assisted methanolic Trametes versicolor extract was evaluated for its antimicrobial and anti-inflammatory efficacy. Mushroom extract showed significantly (p < 0.05) higher total phenolic content (48.71 mg/g) followed by total flavonoid content (13.13 mg/g), ascorbic a...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02397-w
更新日期:2020-09-01 00:00:00
abstract::The different developmental stage-associated microbiota of the peach fruit fly, Bactrocera zonata (Diptera: Tephritidae), was characterized using 16S rRNA gene (V3-V4 region) metabarcoding on the Illumina HiSeq platform. Taxonomically, at 97% similarity, there were total 16 bacterial phyla, comprising of 24 classes, 5...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02381-4
更新日期:2020-09-01 00:00:00
abstract::The impacts of Ho and Li (0, 10, 50, 200 mg/L) were tested towards the growth of four basidiomycetous fungal species, their ability to decolorise synthetic dyes (Reactive Green 19, Reactive Orange 16, Reactive Black 5), and produce oxidative enzymes. All species; Agrocybe dura, Skeletocutis biguttulata, Exidia sacchar...
journal_title:3 Biotech
pub_type:
doi:10.1007/s13205-020-02355-6
更新日期:2020-08-01 00:00:00
abstract::In this study, a novel and stable gene transformation system was developed under control of Maize Proteinase Inhibitor (MPI) as an inducible promoter using the Mesoporous Silica Nanoparticles (MSNs). The functionalized MSNs with a proper particle size were synthesized and attached to a recombinant construct (pDNA) con...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02359-2
更新日期:2020-08-01 00:00:00
abstract::The electrochemical DNA biosensor has been developed for the detection of Listeria monocytogenes in raw milk samples. The electrochemical studies of the developed biosensor was recorded by cyclic voltammetry (CV) and electrochemical impedance (EI) using methylene blue (MB) and potassium ferricyanide K3Fe(CN)-6 as redo...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02315-0
更新日期:2020-07-01 00:00:00
abstract::Salmonella typhimurium (S. typhimurium) represents an important global public health problem and has the ability to survive under desiccation conditions in foods and food processing facilities for years. The aim of this study was to investigate the effects of Allium sativum (A. sativum) and Cuminum cyminum (C. cyminum...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02286-2
更新日期:2020-07-01 00:00:00
abstract::The present paper aims to explore the rhizospheric bacterial communities associated with Saccharum arundinaceum grown on organometallic pollutants-rich hazardous distillery sludge. The sequence analysis of 16S rRNA V3-V4 hypervariable region with Illumina MiSeq platform showed 621,897 OTUs derived from rhizospheric an...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02310-5
更新日期:2020-07-01 00:00:00
abstract::Stem cells are becoming increasingly popular in public lexicon owing to their prospective applications in the biomedical and therapeutic domains. Extensive research has found various independent stem cell systems fulfilling specific needs of plant development. Plant stem cells are innately undifferentiated cells prese...
journal_title:3 Biotech
pub_type: 杂志文章,评审
doi:10.1007/s13205-020-02247-9
更新日期:2020-07-01 00:00:00
abstract::Present study mainly aimed to ascertain the distribution characteristics of gene-based microsatellite loci and to develop polymorphic SSR markers from the already available transcriptome data of Elaeis guineensis Jacq, an important oil crop. From this study, we identified the sum of 5791 SSRs across 51,425 unigenes fr...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02269-3
更新日期:2020-06-01 00:00:00
abstract::This study aimed to explore the expressions of signal transducer and activator of transcription 3 (STAT3) and a gene associated with retinoid-interferon induced mortality (Grim19) in epithelial ovarian cancer (EOC), and to determine their correlations with tumor progression and metastasis as well as the related mechan...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02237-x
更新日期:2020-06-01 00:00:00
abstract::Chinese and imported pig breeds differ in fat production potential, which is associated with the polymorphisms in the 5' proximal regulating region (5'PRR) of thyroid hormone responsive gene (THRSP). In three Chinese breeds (Dingyuan, CDY; Wannanhua, CWH; and Jixi, CJX) and one introduced breed (Yorkshire, YKS), three...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02266-6
更新日期:2020-06-01 00:00:00
abstract::The domestic yak (Bos grunniens) from the Qinghai-Tibet Plateau is an important animal model in high-altitude adaptation studies. Here, we performed the genome-wide selective sweep analysis to identify the candidate copy number variation (CNV) for the high-altitude adaptation of yaks. A total of 531 autosomal CNVs wer...
journal_title:3 Biotech
pub_type:
doi:10.1007/s13205-020-02254-w
更新日期:2020-06-01 00:00:00
abstract::In the present study, we have experimentally and theoretically studied the free-radical quenching property of dihydrocanaric acid (DCA) isolated from seedpods of Holarrhena antidysenterica. A modified method was used to estimate the nitric oxide scavenging effect of the DCA (significant activity of 75.22%) along with ...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02221-5
更新日期:2020-06-01 00:00:00
abstract::Drought is one of the major constraints in wheat production and causes a huge loss at grain-filling stage. In this study we highlighted the response of different wheat genotypes under drought stress at the grain-filling stage. Field experiments were conducted to evaluate 72 wheat (Triticum aestivum L.) genotypes under...
journal_title:3 Biotech
pub_type: 杂志文章
doi:10.1007/s13205-020-02264-8
更新日期:2020-06-01 00:00:00