解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::In the European rabbit (Oryctolagus cuniculus), a polytocous livestock species, the number of teats indirectly impacts the doe reproduction efficiency and, in turn, the sustainable production of rabbit meat. In this study, we carried out a genome-wide association study (GWAS) for the total number of teats in 247 Itali...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.13036
更新日期:2021-01-11 00:00:00
abstract::A GWAS was performed using the genotypes obtained by PorcineSNP60 v2 BeadChip and 11 phenotypic traits (carcass lean meat percentage; backfat thickness; Longissimus thoracis muscle thickness; lightness; backfat thickness measured with caliper at the midline; meat pH measured at about 1 h post mortem and 24 h post mort...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.13013
更新日期:2020-12-01 00:00:00
abstract::In this study, we analyzed 93 whole genomes from Chinese spot-billed ducks (CSB), meat-type ducks (MET), and egg and dual purpose-type ducks (EDT) to characterize the genetic material flowing between the CSB and modern ducks. Using a frequency of shared identical-by-descent method, approximately 10.9 Mb introgression ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.13002
更新日期:2020-12-01 00:00:00
abstract::South Africa has a diverse array of phenotypically distinct and locally adapted sheep breeds that have been developed for different production systems ranging from mutton to wool and pelt, and some dual-purpose and nondescript breeds kept by smallholder farmers. This study investigated genetic diversity, population ge...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12991
更新日期:2020-12-01 00:00:00
abstract::Intensive artificial selection has been imposed in Yunshang black goats, the first black specialist mutton goat breed in China, with a breeding object of improving reproductive performance, which has contributed to reshaping of the genome including the characterization of SNP, ROH and haplotype. However, variation in ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12999
更新日期:2020-12-01 00:00:00
abstract::Cryptorchidism is the most common disorder of sex development in dogs and testosterone plays a crucial role in the inguinal phase of the testes descending into the scrotum. The molecular background of impaired testosterone synthesis in the testes of cryptorchid dogs is poorly elucidated. In this study, we analyzed the...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12977
更新日期:2020-10-01 00:00:00
abstract::Milk production is one of the most important characteristics of dairy sheep, and the identification of genes affecting milk production traits is critical to understanding the genetics and improve milk production in future generations. Three statistical techniques, namely GWAS, ridge-regression BLUP and BayesC ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12956
更新日期:2020-08-01 00:00:00
abstract::The cAMP responsive element binding protein (CREB)-regulated transcription coactivator 3 (CRTC3) is a member of the CRTC protein family and plays an important role in energy metabolism. The aim of this study was to determine if the expression of porcine CRTC3 is related to intramuscular fat (IMF) deposition and meat q...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12945
更新日期:2020-08-01 00:00:00
abstract::In domestic goats, the polled intersex syndrome (PIS) refers to XX female-to-male sex reversal associated with the absence of horn growth (polled). The causal variant was previously reported as a 11.7 kb deletion at approximately 129 Mb on chromosome 1 that affects the transcription of both FOXL2 and several long non-...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12918
更新日期:2020-06-01 00:00:00
abstract::The bumblebee, Bombus terrestris, is an important pollinator commercially used on a global scale. The exported subspecies B. t. terrestris has colonised diverse environments, in some cases displacing wild pollinators to the verge of local extinction. In this sense, the native Iberian subspecies B. t. lusitanicus may b...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12874
更新日期:2020-02-01 00:00:00
abstract::Fractures are medical conditions that compromise the athletic potential of horses and/or the safety of jockeys. Therefore, the reduction of fracture risk is an important horse and human welfare issue. The present study used molecular genetic approaches to determine the effect of genetic risk for fracture at four candi...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12866
更新日期:2020-02-01 00:00:00
abstract::Intramuscular fat (IMF) is one of the main meat quality traits for breeding programmes in livestock species. The main objective of this study was to identify genomic regions associated with IMF content comparing two rabbit populations divergently selected for this trait, and to generate a list of putative candidate ge...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12873
更新日期:2020-02-01 00:00:00
abstract::In previous GWAS carried out in a Duroc commercial line (Lipgen population), we detected on pig chromosomes 3, 4 and 14 several QTL for gluteus medius muscle redness (GM a*), electric conductivity in the longissimus dorsi muscle (LD CE) and vaccenic acid content in the LD muscle (LD C18:1 n - 7), respectively. We have...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12864
更新日期:2020-02-01 00:00:00
abstract::The Ehlers-Danlos syndromes (EDSs) are a heterogeneous group of inherited connective tissue disorders characterized by skin hyperextensibility, joint hypermobility and tissue fragility. Inherited disorders similar to human EDS have been reported in different mammalian species. In the present study, we investigated a f...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12830
更新日期:2019-10-01 00:00:00
abstract::Yolk ratio is an important production index in the salted duck egg industry. Yolk constituents are deposited during development of follicles. However, the molecular mechanism responsible for different yolk ratios in laying ducks remains elusive. In this study, Shaoxing ducks laying eggs with different yolk ratios were...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12820
更新日期:2019-10-01 00:00:00
abstract::RNA editing is a post-transcription maturation process that diversifies genomically encoded information and can lead to transcriptome diversity. Thanks to next-generation sequencing technologies, a large number of editing sites have been identified in different species. Although this mechanism is well described in mam...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12818
更新日期:2019-10-01 00:00:00
abstract::A specific white spotting phenotype, termed finching or line-backed spotting, is known for all Pinzgauer cattle and occurs occasionally in Tux-Zillertaler cattle, two Austrian breeds. The so-called Pinzgauer spotting is inherited as an autosomal incompletely dominant trait. A genome-wide association study using 27 whi...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12821
更新日期:2019-10-01 00:00:00
abstract::Embryonic survival rate, an important factor in the fecundity of sows, is affected by endometrium-secreting histotroph. A higher concentration of calcium ion has been observed in the uterus of highly prolific Erhualian sows (EH) compared with those of less prolific (EL) sows. This suggests that EH sows have better est...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12788
更新日期:2019-08-01 00:00:00
abstract::The recent extension of genetic tools to the domestic cat, together with the serendipitous consequences of selective breeding, have been essential to the study of the genetic diseases that affect them. Cats are increasingly presented for veterinary surveillance and share many of human's heritable diseases, allowing th...
journal_title:Animal genetics
pub_type: 杂志文章,评审
doi:10.1111/age.12799
更新日期:2019-08-01 00:00:00
abstract::In 2015, cholesterol deficiency (CD) was reported for the first time as a new recessive defect in Holstein cattle. After GWAS mapping and identification of a disease-associated haplotype, a causative loss-of-function variant in APOB was identified. CD-clinically affected APOB homozygotes showed poor development, inter...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12801
更新日期:2019-08-01 00:00:00
abstract::Overlapping runs of homozygosity (ROH islands) shared by the majority of a population are hypothesized to be the result of selection around a target locus. In this study we investigated the impact of selection for coat color within the Noriker horse on autozygosity and ROH patterns. We analyzed overlapping homozygous ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12797
更新日期:2019-08-01 00:00:00
abstract::Body weight is a complex trait in cattle associated with commonly used commercial breeding measurements related to growth. Although many quantitative trait loci (QTL) for body weight have been identified in cattle so far, searching for genetic determinants in different breeds or environments is promising. Therefore, w...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12786
更新日期:2019-06-01 00:00:00
abstract::Glutaminyl-peptide cyclotransferase-like (QPCTL) is an isoenzyme of glutaminyl-peptide cyclotransferase (QPCT). QPCTL and QPCT catalyze the formation of N-terminal modified pyroglutamate-fractalkine and the chemokine CCL2. The objective of this study was to investigate the association between insertions/deletions in t...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12741
更新日期:2019-06-01 00:00:00
abstract::The European sea bass (Dicentrarchus labrax L.) is a marine fish of key economic and cultural importance in Europe. It is now more an aquaculture than a fisheries species (>96% of the production in 2016), although modern rearing techniques date back only from the late 1980s. It also has high interest for evolutionary ...
journal_title:Animal genetics
pub_type: 杂志文章,评审
doi:10.1111/age.12779
更新日期:2019-06-01 00:00:00
abstract::The objective of genome mapping is to achieve valuable insight into the connection between gene variants (genotype) and observed traits (phenotype). Part of that objective is to understand the selective forces that have operated on a population. Finding links between genotype-phenotype changes makes it possible to ide...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12772
更新日期:2019-06-01 00:00:00
abstract::Genome-wide association studies (GWASes) have been performed to search for genomic regions associated with residual feed intake (RFI); however inconsistent results have been obtained. A meta-analysis may improve these results by decreasing the false-positive rate. Additionally, pathway analysis is a powerful tool that...
journal_title:Animal genetics
pub_type: 杂志文章,meta分析
doi:10.1111/age.12761
更新日期:2019-04-01 00:00:00
abstract::Recently, the Swiss breeding association reported an increasing number of white-spotted cattle in the Brown Swiss breed, which is normally solid brown coloured. A total of 60 Brown Swiss cattle with variably sized white abdominal spots, facial markings and depigmented claws were collected for this study. A genome-wide...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12751
更新日期:2019-02-01 00:00:00
abstract::Almost half of all US households own a dog (Canis familiaris). Though these household pets can attack humans and other animals, they are also frequently victims of cruelty, neglect and theft. In human-oriented investigations, the tendency of domestic dogs to leave behind physical traces (such as hair) can serve as val...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12758
更新日期:2019-02-01 00:00:00
abstract::After domestication 11 000 years ago in Asia Minor, the goat followed human migration to Europe and Asia. It was then introduced in Africa and is now raised all over the world. In this study, we exploited a dataset composed of 54 000 SNPs (Illumina goat DNA chip) to analyze the genetic diversity of 223 individuals bel...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12752
更新日期:2019-02-01 00:00:00
abstract::The service sire has been recognized as an important factor affecting herd fertility in dairy cattle. Recent studies suggest that genetic factors explain part of the difference in fertility among Holstein sires. The main objective of this study was to dissect the genetic architecture of sire fertility in US Jersey cat...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12710
更新日期:2018-10-01 00:00:00
abstract::Rabbit fur characteristics are primarily genetically determined traits. We used Illumina high-throughput sequencing technology to assess gene expression in the skin tissues of rabbits derived from a cross between Wanxi Angora rabbits and Rex rabbits, which exhibit differential characteristics of short and long wool re...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12701
更新日期:2018-10-01 00:00:00
abstract::In the present study, data from four F2 crosses were analysed and used to study the linkage disequilibrium (LD) structure within and across the crosses. Genome-wide association analyses (GWASes) for conductivity and dressing out meat traits were conducted using single-marker and Bayesian multi-marker models using the ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12684
更新日期:2018-10-01 00:00:00
abstract::The crest in chicken consists of elongated and upraised feathers, as seen in various breeds such as the Silkie chicken. Recently, the still unknown causative mutation for the crest phenotype was assigned to chromosome 33 and an ectopic expression of HOXC8 was shown. The aim this study was to evaluate whether the crest...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12674
更新日期:2018-08-01 00:00:00
abstract::Rumplessness in Hongshan chickens has been reported as a novel sex-linked characteristic. Re-sequencing data suggest that a pseudogene on the Z chromosome, LOC431648, is affiliated with this phenotype. In this study, we chose 23 rumpless and 25 normal Hongshan chickens to localize the potential variation by means of a...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12664
更新日期:2018-08-01 00:00:00
abstract::Loss-of-function variants in the MC1R gene cause recessive red or yellow coat-colour phenotypes in many species. The canine MC1R:c.916C>T (p.Arg306Ter) variant is widespread and found in a homozygous state in many uniformly yellow- or red-coloured dogs. We investigated cream-coloured Australian Cattle Dogs whose coat ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12660
更新日期:2018-08-01 00:00:00
abstract::Previously, we re-sequenced the whole genomes of eight Holstein bulls with high or low milk protein and fat percentage, and we detected two indels in the ACACB (acetyl-CoA carboxylase beta) gene that were polymorphic between the two groups. Thus, we considered ACACB as a promising candidate gene potentially affecting ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12651
更新日期:2018-06-01 00:00:00
abstract::Genetic relatedness of 24 animals belonging to seven Indian cattle breeds was studied using high throughput genotyping-by-sequencing (GBS) markers. GBS produced 93.6 million reads with an average of about 3.9 million reads per animal. A total of 107 488 SNPs were identified in these individuals. When only one SNP per ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12650
更新日期:2018-06-01 00:00:00
abstract::Identification of microRNAs (miRNAs), target genes and regulatory networks associated with innate immune and inflammatory responses and tissue damage is essential to elucidate the molecular and genetic mechanisms for resistance to mastitis. In this study, a combination of Solexa sequencing and custom miRNA chip approa...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12628
更新日期:2018-02-01 00:00:00
abstract::The Icelandic horse is a breed known mainly for its ability to perform the ambling four-beat gait 'tölt' and the lateral two-beat gait pace. The natural ability of the breed to perform these alternative gaits is highly desired by breeders. Therefore, the discovery that a nonsense mutation (C>A) in the DMRT3 gene was t...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12610
更新日期:2017-12-01 00:00:00
abstract::The 70 kilodalton heat shock proteins (Hsp70) are highly conserved molecular chaperones which have a crucial role in the stress response of the cell. In mammals, the Hsp70 proteins are encoded by a cluster of three genes: HSPA1A, HSPA1B and HSPA1L. In bovines, this cluster is located on chromosome 23 downstream of the...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/age.12561
更新日期:2017-08-01 00:00:00