A complex structural variant at the KIT locus in cattle with the Pinzgauer spotting pattern.

abstract：:MicroRNA (miRNA) is a class of single-stranded small (19-24nt) regulatory RNA that silences gene expression post-transcriptionally. miRNAs regulate a wide range of biological processes through the recognition of complementary sequences between miRNAs and their target genes. Profiling studies in livestock have revealed...

journal_title：Animal genetics

authors： Liu HC,Hicks JA,Trakooljul N,Zhao SH

更新日期：2010-06-01 00:00:00

abstract：:Monoclonal antibodies specific for equine T lymphocyte subpopulations were produced and procedures for the continuous culture of equine lymphocytes were developed. These reagents and procedures were used to analyse the appearance, maturation and functions of T lymphocytes in normal horses and in T lymphocyte deficient...

journal_title：Animal genetics

authors： Perryman LE,Wyatt CR,Magnuson NS,Mason PH

更新日期：1988-01-01 00:00:00

abstract：:Genomic DNAs from animals representing six breeds of cattle (Angus, Brahman, Hereford, Holstein, Jersey and Texas Longhorn) were screened with cloned gene probes in a search for restriction fragment length polymorphisms (RFLPs). Eleven RFLPs were identified using seven different probes: growth hormone, prolactin, oste...

journal_title：Animal genetics

authors： Theilmann JL,Skow LC,Baker JF,Womack JE

更新日期：1989-01-01 00:00:00

abstract：:To increase the number of type I loci on the chicken linkage map, chicken genes containing microsatellite sequences (TAn, CAn, GAn, An) were selected from the nucleotide sequence database and primers were developed to amplify the repeats. Initially, 40 different microsatellites located within genes were tested on a pa...

journal_title：Animal genetics

authors： Groenen MA,Crooijmans RP,Dijkhof RJ,Acar R,van der Poel JJ

更新日期：1999-12-01 00:00:00

abstract：:This study presents evidence that sheep haemopexin phenotypes are genetically controlled by three alleles, HpxA, HpxB1 and HpxB2, of a single autosomal locus. Frequencies of two alleles, HpxA and HpxB (HpxB encompasses two isoalleles, HpxB1 and HpxB2), were studied in eight sheep breeds in Czechoslovakia. The frequenc...

journal_title：Animal genetics

authors： Stratil A,Bobák P,Margetín M,Glasnák V

更新日期：1989-01-01 00:00:00

abstract：:Three genomic clones were isolated from a size-selected pig DNA library by hybridization with a DNA-fingerprint probe. Analysis at the sequence level revealed that all three clones contain interrupted stretches of triplet repeats mainly composed of CAC and CAT triplets. Evaluation of the corresponding loci for polymor...

journal_title：Animal genetics

authors： Coppieters W,Van de Weghe A,Depicker A,Coppieters J,Peelman L,Van Zeveren A,Bouquet Y

更新日期：1995-10-01 00:00:00

abstract：:The KIT locus has been suggested to be a strong candidate region linked with whole-body roan in the F(2) population produced by intercrosses between Landrace and Korean Native pigs. In this manuscript, we report the finding of a novel alternative splicing event in the porcine KIT gene that results in the skipping of e...

journal_title：Animal genetics

authors： Lim HT,Zhong T,Cho IC,Seo BY,Kim JH,Lee SS,Ko MS,Park HB,Kim BW,Lee JH,Jeon JT

更新日期：2011-08-01 00:00:00

abstract：:The aim of this study was to determine the allele frequency of the glycogen synthase 1 (GYS1) mutation associated with polysaccharide storage myopathy type 1 in the Austrian Noriker horse. Furthermore, we examined the influence of population substructures on the allele distribution. The study was based upon a comprehe...

journal_title：Animal genetics

authors： Druml T,Grilz-Seger G,Neuditschko M,Brem G

更新日期：2017-02-01 00:00:00

abstract：:With the recent development of whole-exome sequencing enrichment designs for the dog, a novel tool for disease-association studies became available. The aim of disease-association studies is to identify one or a very limited number of putative causal variants or genes from the large pool of genetic variation. To maxim...

journal_title：Animal genetics

authors： Broeckx BJ,Coopman F,Verhoeven GE,De Keulenaer S,De Meester E,Bavegems V,Smets P,Van Ryssen B,Van Nieuwerburgh F,Deforce D

更新日期：2016-04-01 00:00:00

abstract：:In domestic goats, the polled intersex syndrome (PIS) refers to XX female-to-male sex reversal associated with the absence of horn growth (polled). The causal variant was previously reported as a 11.7 kb deletion at approximately 129 Mb on chromosome 1 that affects the transcription of both FOXL2 and several long non-...

journal_title：Animal genetics

authors： Simon R,Lischer HEL,Pieńkowska-Schelling A,Keller I,Häfliger IM,Letko A,Schelling C,Lühken G,Drögemüller C

更新日期：2020-06-01 00:00:00

abstract：:Genome-wide association studies (GWASes) have been performed to search for genomic regions associated with residual feed intake (RFI); however inconsistent results have been obtained. A meta-analysis may improve these results by decreasing the false-positive rate. Additionally, pathway analysis is a powerful tool that...

journal_title：Animal genetics

authors： Duarte DAS,Newbold CJ,Detmann E,Silva FF,Freitas PHF,Veroneze R,Duarte MS

更新日期：2019-04-01 00:00:00

abstract：:Copy number variation (CNV), an essential form of genetic variation, has been increasingly recognized as one promising genetic marker in the analysis of animal genomes. Here, we used the Equine 70K single nucleotide polymorphism genotyping array for the genome-wide detection of CNVs in 96 horses from three diverse Chi...

journal_title：Animal genetics

authors： Kader A,Liu X,Dong K,Song S,Pan J,Yang M,Chen X,He X,Jiang L,Ma Y

更新日期：2016-10-01 00:00:00

abstract：:Plasma samples of 1126 dogs belonging to 21 different European breeds were analysed by two-dimensional agarose gel (pH 5.4 or pH 8.6)--horizontal polyacrylamide gel (pH 9.0) electrophoresis, followed by general-protein staining of gels. Genetic polymorphism was detected for five as yet unidentified proteins designated...

journal_title：Animal genetics

authors： Juneja RK,Arnold IC,Gahne B,Bouw J

更新日期：1987-01-01 00:00:00

abstract：:A quantitative trait locus (QTL) for boar fat androstenone levels has been identified near the SSC7 centromere in a Large White × Meishan cross. Backcrosses were produced to isolate the Chinese haplotype in a European genetic background. The expression of 25 genes from the QTL region was studied in the testes and live...

journal_title：Animal genetics

authors： Robic A,Fève K,Larzul C,Billon Y,van Son M,Liaubet L,Sarry J,Milan D,Grindflek E,Bidanel JP,Riquet J

更新日期：2011-12-01 00:00:00

abstract：:Polymorphic bands were detected within the DQB and DRB regions of the ovine major histocompatibility complex by probing TaqI digested DNA from three large sheep half-sib families derived from a highly resistant ram. All animals were phenotypically assessed for Haemonchus contortus resistance by faecal egg counts and a...

journal_title：Animal genetics

authors： Blattman AN,Hulme DJ,Kinghorn BP,Woolaston RR,Gray GD,Beh KJ

更新日期：1993-08-01 00:00:00

abstract：:The objective of this study was to identify twinning rate quantitative trait loci (QTL) by typing pooled samples in a preliminary screening followed by interval mapping to test QTL effects. Four elite North American Holstein half-sib sire families with high twinning rate predicted transmitting abilities (PTA) were use...

journal_title：Animal genetics

authors： Cobanoglu O,Berger PJ,Kirkpatrick BW

更新日期：2005-08-01 00:00:00

abstract：:Good eggshell quality is important for both table egg quality and chicken reproductive performance. Weak eggshells cause economic losses in all production steps. Poor eggshell quality also poses increased risk for Salmonella infections. Eggshell quality has been a difficult trait to improve by traditional breeding, as...

journal_title：Animal genetics

authors： Tuiskula-Haavisto M,Honkatukia M,Preisinger R,Schmutz M,de Koning DJ,Wei WH,Vilkki J

更新日期：2011-06-01 00:00:00

abstract：:Polymerase chain reaction (PCR) primers specific to exon 2 of the bovine lymphocyte antigen (BoLA)-DRB3 gene were successfully used to amplify the equivalent region in 469 American bison (Bison bison). In domestic cattle, alleles of DRB3 are assigned through a restriction fragment length polymorphism (RFLP) analysis o...

journal_title：Animal genetics

authors： Morris BG,Spencer MC,Stabile S,Dodd JN

更新日期：1994-06-01 00:00:00

abstract：:Nucleotide sequence analysis of polymerase chain reaction products confirmed that ev21 integrated into one of two large homologous elements on the Z chromosome of late-feathering (LF) White Leghorn chickens. Southern blots of NotI-, NaeI-, KspI- and BamHI-digested DNA from early-feathering (EF) and LF White Leghorns, ...

journal_title：Animal genetics

authors： Iraqi F,Smith EJ

更新日期：1995-06-01 00:00:00

abstract：:Equine mitochondrial DNA (mtDNA) phylogeny reconstruction reveals a complex pattern of variation unlike that seen in other large domesticates. It is likely that this pattern reflects a process of multiple and repeated, although not necessarily independent, domestication events. Until now, no clear geographic affiliati...

journal_title：Animal genetics

authors： McGahern A,Bower MA,Edwards CJ,Brophy PO,Sulimova G,Zakharov I,Vizuete-Forster M,Levine M,Li S,MacHugh DE,Hill EW

更新日期：2006-10-01 00:00:00

abstract：:The myxovirus resistance (Mx) proteins belong to the dynamin superfamily and are important for innate host defence against RNA viruses. In this study, we demonstrate that positive elements are present in the two promoter regions of -2713 to -2565 and -688 to -431 in the porcine MX1 gene. Sequencing and alignment of th...

journal_title：Animal genetics

authors： Li Y,Liang S,Liu H,Sun Y,Kang L,Jiang Y

更新日期：2015-08-01 00:00:00

abstract：:Almost half of all US households own a dog (Canis familiaris). Though these household pets can attack humans and other animals, they are also frequently victims of cruelty, neglect and theft. In human-oriented investigations, the tendency of domestic dogs to leave behind physical traces (such as hair) can serve as val...

journal_title：Animal genetics

authors： Kanthaswamy S,Oldt RF,Montes M,Falak A

更新日期：2019-02-01 00:00:00

abstract：:Here we tested the segregation and paternal compatibility of markers INRA124 and INRA126 on female DNA in 10 different cattle families, in order to clarify the usefulness of these microsatellites for the study of male-mediated population processes in cattle. Their performance was compared with that of four microsatell...

journal_title：Animal genetics

authors： Pérez-Pardal L,Royo LJ,Alvarez I,de León FA,Fernández I,Casais R,Goyache F

更新日期：2009-08-01 00:00:00

abstract：:The recent extension of genetic tools to the domestic cat, together with the serendipitous consequences of selective breeding, have been essential to the study of the genetic diseases that affect them. Cats are increasingly presented for veterinary surveillance and share many of human's heritable diseases, allowing th...

journal_title：Animal genetics

authors： Samaha G,Beatty J,Wade CM,Haase B

更新日期：2019-08-01 00:00:00

abstract：:Cytochrome P450-aromatase enzyme (CYP19), which catalyses the conversion of androgens to oestrogens, is critical in ovarian differentiation and hence in the sex differentiation pathways of non-mammalian vertebrates. As in other fish species, distinct ovarian and brain aromatase genes have been identified in the Nile T...

journal_title：Animal genetics

authors： Harvey SC,Kwon JY,Penman DJ

更新日期：2003-02-01 00:00:00

abstract：:Yolk ratio is an important production index in the salted duck egg industry. Yolk constituents are deposited during development of follicles. However, the molecular mechanism responsible for different yolk ratios in laying ducks remains elusive. In this study, Shaoxing ducks laying eggs with different yolk ratios were...

journal_title：Animal genetics

authors： Du X,Ren JD,Xu XQ,Chen GH,Huang Y,Du JP,Tao ZR,Cai ZX,Lu LZ,Yang H

更新日期：2019-10-01 00:00:00

abstract：:The Japanese quail (Coturnix japonica; JQ) is one of the domesticated fowl species of Japan. To provide DNA sequence information for examination of its phylogenetic position in the order Galliformes, the complete sequence of the JQ mitochondria was determined. Sequence analysis revealed that the JQ mitochondrial genom...

journal_title：Animal genetics

authors： Nishibori M,Hayashi T,Tsudzuki M,Yamamoto Y,Yasue H

更新日期：2001-12-01 00:00:00

abstract：:In 2015, cholesterol deficiency (CD) was reported for the first time as a new recessive defect in Holstein cattle. After GWAS mapping and identification of a disease-associated haplotype, a causative loss-of-function variant in APOB was identified. CD-clinically affected APOB homozygotes showed poor development, inter...

journal_title：Animal genetics

authors： Häfliger IM,Hofstetter S,Mock T,Stettler MH,Meylan M,Mehinagic K,Stokar-Regenscheit N,Drögemüller C

更新日期：2019-08-01 00:00:00

abstract：:Six distinct serotypes of the chicken B blood group system (which encodes the major histocompatibility complex) were identified in a commercial broiler breeder line (Line C). The B serotypes were compared by B-G restriction fragment length polymorphism (RFLP) analysis, allele-specific PCR typing test for B-LBII family...

journal_title：Animal genetics

authors： Livant EJ,Zheng D,Johnson LW,Shi W,Ewald SJ

更新日期：2001-06-01 00:00:00

abstract：:Loss-of-function variants in the MC1R gene cause recessive red or yellow coat-colour phenotypes in many species. The canine MC1R:c.916C>T (p.Arg306Ter) variant is widespread and found in a homozygous state in many uniformly yellow- or red-coloured dogs. We investigated cream-coloured Australian Cattle Dogs whose coat ...

journal_title：Animal genetics

authors： Dürig N,Letko A,Lepori V,Hadji Rasouliha S,Loechel R,Kehl A,Hytönen MK,Lohi H,Mauri N,Dietrich J,Wiedmer M,Drögemüller M,Jagannathan V,Schmutz SM,Leeb T

更新日期：2018-08-01 00:00:00