Genome screen for twinning rate QTL in four North American Holstein families.

Abstract:

:The objective of this study was to identify twinning rate quantitative trait loci (QTL) by typing pooled samples in a preliminary screening followed by interval mapping to test QTL effects. Four elite North American Holstein half-sib sire families with high twinning rate predicted transmitting abilities (PTA) were used in this study. Chromosomes 5, 7, 19 and 23 were not genotyped as these chromosomes were scanned for QTL in these families in a previous study. DNA was extracted from phenotypically extreme sons in each sire family. Two pools were prepared from sons of sires in each phenotypic tail, two each for high and low PTA levels for twinning rates. Each pool contained DNA from 4 to 15% of all sons of the sire depending on family. A total of 268 fluorescently labelled microsatellite markers were tested for heterozygosity in sires. About 135--170 informative markers per family were genotyped using pooled DNA samples. Based on the preliminary evidence for potential twinning rate QTL from pooled typing, interval mapping was performed subsequently on 12 chromosomal regions by family combinations. Evidence of QTL for twinning rate was found in one family on BTA 21 and 29 at a chromosome-wide P<0.05 and on BTA 8, 10 and 14 with a chromosome-wide P<0.01.

journal_name

Anim Genet

journal_title

Animal genetics

authors

Cobanoglu O,Berger PJ,Kirkpatrick BW

doi

10.1111/j.1365-2052.2005.01299.x

subject

Has Abstract

pub_date

2005-08-01 00:00:00

pages

303-8

issue

4

eissn

0268-9146

issn

1365-2052

pii

AGE1299

journal_volume

36

pub_type

杂志文章
  • Mapping of expressed sequence tags from a porcine early embryonic cDNA library.

    abstract::The goal of this study was to identify and map genes expressed during the elongation phase of embryogenesis in swine. Expressed sequence tags were analysed from a previously described porcine cDNA library prepared from elongating swine embryos. Average insert length of randomly selected clones was approximately 600 bp...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2052.2001.00739.x

    authors: Smith TP,Fahrenkrug SC,Rohrer GA,Simmen FA,Rexroad CE,Keele JW

    更新日期:2001-04-01 00:00:00

  • QTL detection on porcine chromosome 12 for fatty-acid composition and association analyses of the fatty acid synthase, gastric inhibitory polypeptide and acetyl-coenzyme A carboxylase alpha genes.

    abstract::Refinement of previous QTL on porcine chromosome 12 for fatty-acid composition and a candidate gene association analysis were conducted using an Iberian x Landrace cross. The concentrations of ten fatty acids were assayed in backfat tissue from which four metabolic ratios were calculated for 403 F2 animals. Linkage an...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2007.01668.x

    authors: Muñoz G,Alves E,Fernández A,Ovilo C,Barragán C,Estellé J,Quintanilla R,Folch JM,Silió L,Rodríguez MC,Fernández AI

    更新日期:2007-12-01 00:00:00

  • Restriction fragment length polymorphism (RFLP) of exon 2 of the MhcBibi-DRB3 gene in American bison (Bison bison).

    abstract::Polymerase chain reaction (PCR) primers specific to exon 2 of the bovine lymphocyte antigen (BoLA)-DRB3 gene were successfully used to amplify the equivalent region in 469 American bison (Bison bison). In domestic cattle, alleles of DRB3 are assigned through a restriction fragment length polymorphism (RFLP) analysis o...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1994.tb00409.x

    authors: Morris BG,Spencer MC,Stabile S,Dodd JN

    更新日期:1994-06-01 00:00:00

  • Characterization of a deletion in the Hsp70 cluster in the bovine reference genome.

    abstract::The 70 kilodalton heat shock proteins (Hsp70) are highly conserved molecular chaperones which have a crucial role in the stress response of the cell. In mammals, the Hsp70 proteins are encoded by a cluster of three genes: HSPA1A, HSPA1B and HSPA1L. In bovines, this cluster is located on chromosome 23 downstream of the...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12561

    authors: Suqueli García MF,Castellote MA,Feingold SE,Corva PM

    更新日期:2017-08-01 00:00:00

  • The influence of extracellular matrix and prolactin on global gene expression profiles of primary bovine mammary epithelial cells in vitro.

    abstract::An in vitro bovine mammosphere model was characterized for use in lactational biology studies using a functional genomics approach. Primary bovine mammary epithelial cells cultured on a basement membrane, Matrigel, formed three-dimensional alveoli-like structures or mammospheres. Gene expression profiling during mammo...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2009.01964.x

    authors: Riley LG,Gardiner-Garden M,Thomson PC,Wynn PC,Williamson P,Raadsma HW,Sheehy PA

    更新日期:2010-02-01 00:00:00

  • Marker-derived phylogeny of European cattle supports demic expansion of agriculture.

    abstract::Using frequencies of 86 genes from 23 loci of blood group systems, blood and milk proteins, the genetic relationships among 14 cattle breeds including four native Balkan and four synthetic Balkan-Alp breeds were studied. The dendrogram and nonlinear map construction shows a consensus 'Balkan breed cluster', an 'Alp br...

    journal_title:Animal genetics

    pub_type: 历史文章,杂志文章

    doi:10.1111/j.1365-2052.1994.tb00399.x

    authors: Medjugorac I,Kustermann W,Lazar P,Russ I,Pirchner F

    更新日期:1994-06-01 00:00:00

  • Breed difference and regulatory role of CRTC3 in porcine intramuscular adipocyte.

    abstract::The cAMP responsive element binding protein (CREB)-regulated transcription coactivator 3 (CRTC3) is a member of the CRTC protein family and plays an important role in energy metabolism. The aim of this study was to determine if the expression of porcine CRTC3 is related to intramuscular fat (IMF) deposition and meat q...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12945

    authors: Liu J,Nong Q,Wang J,Chen W,Xu Z,You W,Xie J,Wang Y,Shan T

    更新日期:2020-08-01 00:00:00

  • Female segregation patterns of the putative Y-chromosome-specific microsatellite markers INRA124 and INRA126 do not support their use for cattle population studies.

    abstract::Here we tested the segregation and paternal compatibility of markers INRA124 and INRA126 on female DNA in 10 different cattle families, in order to clarify the usefulness of these microsatellites for the study of male-mediated population processes in cattle. Their performance was compared with that of four microsatell...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2009.01870.x

    authors: Pérez-Pardal L,Royo LJ,Alvarez I,de León FA,Fernández I,Casais R,Goyache F

    更新日期:2009-08-01 00:00:00

  • BoLA class I charge heterogeneity reflects the expression of more than two loci.

    abstract::Internationally recognized allo-antisera in lymphocyte microcytotoxicity assays are thought to detect allelic products of a single highly polymorphic class I locus. A recent report suggested that two bovine lymphocyte antigen (BoLA) class I loci are expressed at the protein level. However, 1D-IEF analysis of BoLA clas...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1994.tb00105.x

    authors: al-Murrani SW,Glass EJ,Hopkins J

    更新日期:1994-06-01 00:00:00

  • Mapping and characterization of the DQ subregion of the ovine MHC.

    abstract::A map of the ovine MHC class II DQ subregion has been constructed from overlapping cosmid clones. This region consists of two loci linked on a linear tract of 130 kb DNA. Each locus consists of a DQA and a DQB gene in a tail-to-tail orientation. The genes in each locus are transcribed but only those designated DQ1 exp...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1994.tb00200.x

    authors: Wright H,Ballingall KT

    更新日期:1994-08-01 00:00:00

  • PCR-RFLP analysis of the cytochrome b gene in horse mitochondrial DNA.

    abstract::The mitochondrial DNA sequence of cytochrome b gene in a Thoroughbred horse was determined. By comparing DNA sequences between the Thoroughbred and published sequence data (two horses and one Grevyi zebra), polymerase chain reaction (PCR) primers were designed for amplification of a 590 bp DNA fragment in the cytochro...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1996.tb00979.x

    authors: Ishida N,Hasegawa T,Oyunsuren T,Mukoyama H

    更新日期:1996-10-01 00:00:00

  • Quantitative trait loci for body growth and sex determination in the hermaphrodite teleost fish Sparus aurata L.

    abstract::Gilthead sea bream (Sparus aurata L.) is an important marine fish in Mediterranean aquaculture. Sex determination by age and/or body weight is a critical life-history trait, the genetic basis for which is largely unknown in this sequential hermaphrodite species. Herein, we performed a partial genome scan to map quanti...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2012.02346.x

    authors: Loukovitis D,Sarropoulou E,Batargias C,Apostolidis AP,Kotoulas G,Tsigenopoulos CS,Chatziplis D

    更新日期:2012-12-01 00:00:00

  • Mapping and SNP analysis of bovine candidate genes for meat and carcass quality.

    abstract::The chromosomal localization of 13 bovine genes was determined using radiation hybrid (RH) mapping. The RH mapping data were in agreement with published data using either linkage, somatic cell hybrids or in situ hybridization. Mutation analysis using single-stranded conformational polymorphism, restriction fragment le...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2052.2003.01008.x

    authors: Haegeman A,Williams JL,Law A,Van Zeveren A,Peelman LJ

    更新日期:2003-10-01 00:00:00

  • Solexa sequencing and custom microRNA chip reveal repertoire of microRNAs in mammary gland of bovine suffering from natural infectious mastitis.

    abstract::Identification of microRNAs (miRNAs), target genes and regulatory networks associated with innate immune and inflammatory responses and tissue damage is essential to elucidate the molecular and genetic mechanisms for resistance to mastitis. In this study, a combination of Solexa sequencing and custom miRNA chip approa...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12628

    authors: Ju Z,Jiang Q,Liu G,Wang X,Luo G,Zhang Y,Zhang J,Zhong J,Huang J

    更新日期:2018-02-01 00:00:00

  • Fine mapping of porcine SSC14 QTL and SCD gene effects on fatty acid composition and melting point of fat in a Duroc purebred population.

    abstract::The stearoyl-CoA desaturase (delta-9-desaturase; SCD) gene is a candidate gene for fatty acid composition. It is located on pig SSC14 in a region where quantitative trait loci (QTL) for fatty acid composition were previously detected in a Duroc purebred population. The objective of the present study was to fine map th...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2011.02236.x

    authors: Uemoto Y,Nakano H,Kikuchi T,Sato S,Ishida M,Shibata T,Kadowaki H,Kobayashi E,Suzuki K

    更新日期:2012-04-01 00:00:00

  • QTL analysis of body weight and conformation score in commercial broiler chickens using variance component and half-sib analyses.

    abstract::The aim of the study was to investigate quantitative trait loci (QTL) in previously identified regions of chicken chromosomes 1, 4 and 5 relating to 40-day body weights and conformation scores. Half-sib (HS) and variance component analyses were implemented and compared using QTL Express software. Data were from a two-...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2006.01424.x

    authors: Rowe SJ,Windsor D,Haley CS,Burt DW,Hocking PM,Griffin H,Vincent J,De Koning DJ

    更新日期:2006-06-01 00:00:00

  • Twenty years of artificial directional selection have shaped the genome of the Italian Large White pig breed.

    abstract::In this study, we investigated at the genome-wide level if 20 years of artificial directional selection based on boar genetic evaluation obtained with a classical BLUP animal model shaped the genome of the Italian Large White pig breed. The most influential boars of this breed (n = 192), born from 1992 (the beginning ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12392

    authors: Schiavo G,Galimberti G,Calò DG,Samorè AB,Bertolini F,Russo V,Gallo M,Buttazzoni L,Fontanesi L

    更新日期:2016-04-01 00:00:00

  • Differentiation of European cattle by AFLP fingerprinting.

    abstract::The Neolithic introduction of domestic cattle into Europe was followed by differential adaptation, selection, migration and genetic isolation, leading ultimately to the emergence of specialized breeds. We have studied the differentiation of European cattle by amplified fragment length polymorphism (AFLP) fingerprintin...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2007.01554.x

    authors: Negrini R,Nijman IJ,Milanesi E,Moazami-Goudarzi K,Williams JL,Erhardt G,Dunner S,Rodellar C,Valentini A,Bradley DG,Olsaker I,Kantanen J,Ajmone-Marsan P,Lenstra JA,European Cattle Genetic Diversity Consortium.

    更新日期:2007-02-01 00:00:00

  • Albinism in the American mink (Neovison vison) is associated with a tyrosinase nonsense mutation.

    abstract::Albino phenotypes are documented in various species including the American mink. In other species the albino phenotypes are associated with tyrosinase (TYR) gene mutations; therefore TYR was considered the candidate gene for albinism in mink. Four microsatellite markers were chosen in the predicted region of the TYR g...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2008.01788.x

    authors: Anistoroaei R,Fredholm M,Christensen K,Leeb T

    更新日期:2008-12-01 00:00:00

  • East African pigs have a complex Indian, Far Eastern and Western ancestry.

    abstract::In this study, we have characterized the mitochondrial diversity of 81 swine from Uganda. Median-joining network analysis of D-loop sequences from these individuals and others characterized in previous studies allowed us to determine that Ugandan pigs cluster with populations from the West (Europe/North Africa), Far E...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12305

    authors: Noce A,Amills M,Manunza A,Muwanika V,Muhangi D,Aliro T,Mayega J,Ademun R,Sànchez A,Egbhalsaied S,Mercadé A,Masembe C

    更新日期:2015-08-01 00:00:00

  • A PCR-RFLP for KIT associated with tobiano spotting pattern in horses.

    abstract::An MspI polymorphism was identified in intron 13 of the equine homologue of proto-oncogene c-kit (KIT) by comparing DNA sequences from horses with solid coat colour and horses homozygous for the tobiano spotting (To) gene. The allele associated with solid coat colour was designated KM0, while the allele associated wit...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2052.2002.00854.x

    authors: Brooks SA,Terry RB,Bailey E

    更新日期:2002-08-01 00:00:00

  • From information to understanding: the role of model organism databases in comparative and functional genomics.

    abstract::Data integration is key to functional and comparative genomics because integration allows diverse data types to be evaluated in new contexts. To achieve data integration in a scalable and sensible way, semantic standards are needed, both for naming things (standardized nomenclatures, use of key words) and also for kno...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2006.01475.x

    authors: Bult CJ

    更新日期:2006-08-01 00:00:00

  • Accuracy of high-density genotype imputation in Japanese Black cattle.

    abstract::Genotype imputation facilitates the identification of missing genotypes on a high-density array using low-density arrays and has great potential for reducing genotyping costs for cattle populations. However, the imputation quality varies across breeds, which have different effective population sizes. Therefore, the ac...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12314

    authors: Uemoto Y,Sasaki S,Sugimoto Y,Watanabe T

    更新日期:2015-08-01 00:00:00

  • New genomic features of the polled intersex syndrome variant in goats unraveled by long-read whole-genome sequencing.

    abstract::In domestic goats, the polled intersex syndrome (PIS) refers to XX female-to-male sex reversal associated with the absence of horn growth (polled). The causal variant was previously reported as a 11.7 kb deletion at approximately 129 Mb on chromosome 1 that affects the transcription of both FOXL2 and several long non-...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12918

    authors: Simon R,Lischer HEL,Pieńkowska-Schelling A,Keller I,Häfliger IM,Letko A,Schelling C,Lühken G,Drögemüller C

    更新日期:2020-06-01 00:00:00

  • Comparison of joining and constant κ-light chain regions in different cattle breeds.

    abstract::A comparative transcription analysis of Ig κ-light chains (IGK) of the cattle breeds Holstein Friesian (HF), German Black Pied (GBP), German Simmental (GS) and Aubrac (A) revealed three alleles coding for two putative allotypic variants of IGKC. The amino acid residues p.Asp100Asn and p.Thr116Ala were located at the o...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2012.02324.x

    authors: Stein SK,Diesterbeck US,Aboelhassan DM,Czerny CP

    更新日期:2012-12-01 00:00:00

  • Sequence of porcine beta-lactoglobulin cDNA.

    abstract::cDNAs encoding porcine beta-lactoglobulin were isolated and sequenced. The porcine beta-lactoglobulin cDNA is 768bp in length and encodes a pre-protein of 178 amino acids. One additional cDNA clone was found to encode an additional amino acid (lysine) in the mature protein. ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1992.tb00139.x

    authors: Alexander LJ,Beattie CW

    更新日期:1992-01-01 00:00:00

  • Microsatellite DNA markers indicate three genetic lineages in East Asian indigenous goat populations.

    abstract::The genetic differentiation and phylogenetic relationships of 18 indigenous goat populations from seven East Asian countries were analysed based on data obtained from 26 microsatellite DNA markers. The mean number of alleles (MNA) per population ranged from 2.5 to 7.6, with an average of 5.8. Genetic variability estim...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2012.02334.x

    authors: Nomura K,Ishii K,Dadi H,Takahashi Y,Minezawa M,Cho CY,Sutopo,Faruque MO,Nyamsamba D,Amano T

    更新日期:2012-12-01 00:00:00

  • Detection of genome specific monomorphic loci in Bos taurus and Bubalus bubalis with oligodeoxyribonucleotide probe.

    abstract::A synthetic oligodeoxyribonucleotide probe (OAT36) comprising nine repeats of 5'GACA 3' and several enzymes were used to analyse cow, (Bos taurus) and buffalo (Bubalus bubalis) genomes and a number of monomorphic loci were detected in both the species. Different animals from the same species showed an almost 'similar'...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1993.tb00288.x

    authors: Ali S,Gauri,Bala S

    更新日期:1993-06-01 00:00:00

  • A genome-wide association study reveals a QTL influencing caudal supernumerary teats in Holstein cattle.

    abstract::Supernumerary teats represent a common abnormality of the bovine udder. A genome-wide association study was performed based on the proportion of the occurrence of supernumerary teats in the daughters of 1097 Holstein bulls. The heritability of caudal supernumerary teats without mammary gland in this study was 0.604. T...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12215

    authors: Joerg H,Meili C,Ruprecht O,Bangerter E,Burren A,Bigler A

    更新日期:2014-12-01 00:00:00

  • Isolation of microsatellites from a bovine YAC clone harbouring the SOD1 gene.

    abstract::A bovine yeast artificial chromosome (YAC) clone containing the superoxide dismutase 1 (SOD1) gene was used as a template for polymerase chain reaction (PCR) amplification using a conserved short interspersed nuclear element (SINE) primer. Two highly polymorphic microsatellites with nine and eight alleles were isolate...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1997.00158.x

    authors: Band M,Eggen A,Bishop MD,Ron M

    更新日期:1997-10-01 00:00:00