A PCR-RFLP for KIT associated with tobiano spotting pattern in horses.

Abstract:

:An MspI polymorphism was identified in intron 13 of the equine homologue of proto-oncogene c-kit (KIT) by comparing DNA sequences from horses with solid coat colour and horses homozygous for the tobiano spotting (To) gene. The allele associated with solid coat colour was designated KM0, while the allele associated with the tobiano pattern created an additional MspI restriction site and was designated KM1. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) studies using DNA from hair follicles demonstrated that all 129 of 129 tobiano patterned horses possessed the KM1 allele. However, three of 104 solid-coloured thoroughbred horses also possessed the KM1 allele. Therefore, while KM1 is strongly associated with the gene for To, the association is not absolute. However, this test appears more efficacious to identify putative homozygotes for To than current biochemical testing methods using albumin (Alb) and vitamin D binding protein (Gc) haplotypes.

journal_name

Anim Genet

journal_title

Animal genetics

authors

Brooks SA,Terry RB,Bailey E

doi

10.1046/j.1365-2052.2002.00854.x

subject

Has Abstract

pub_date

2002-08-01 00:00:00

pages

301-3

issue

4

eissn

0268-9146

issn

1365-2052

pii

854

journal_volume

33

pub_type

杂志文章
  • Preliminary radiation hybrid map for river buffalo chromosome 6 and comparison to bovine chromosome 3.

    abstract::We present the first radiation hybrid (RH) map of river buffalo (Bubalus bubalis) chromosome 6 (BBU6) developed with a recently constructed river buffalo whole-genome RH panel (BBURH(5000)). The preliminary map contains 33 cattle-derived markers, including 12 microsatellites, 19 coding genes and two ESTs, distributed ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2007.01612.x

    authors: Stafuzza NB,Ianella P,Miziara MN,Agarwala R,Schäffer AA,Riggs PK,Womack JE,Amaral ME

    更新日期:2007-08-01 00:00:00

  • Assessment of DNA fingerprinting for determining genetic diversity in sheep populations.

    abstract::Genomic DNA, prepared from 12 animals from four sheep flocks, was digested with either HaeIII or HinfI and probed with three DNA fingerprinting probes. Mean DNA fingerprint band sharing and band frequency calculated for each flock were used to estimate genetic diversity. Each of the DNA fingerprinting systems showed t...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1993.tb00345.x

    authors: Hermans IF,Morris CA,Chambers GK,Towers NR,Jordan TW

    更新日期:1993-10-01 00:00:00

  • Association analysis of adiponectin and somatostatin polymorphisms on BTA1 with growth and carcass traits in Angus cattle.

    abstract::This study tested positional candidate genes adiponectin (ADIPOQ) and somatostatin (SST) for effects on carcass traits in a commercially relevant cattle population. Both genes are located within a region of BTA1 previously reported to harbour quantitative trait loci (QTL) that affect marbling, quality grade, yield gra...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2006.01528.x

    authors: Morsci NS,Schnabel RD,Taylor JF

    更新日期:2006-12-01 00:00:00

  • Association analyses of single nucleotide polymorphisms in bovine stearoyl-CoA desaturase and fatty acid synthase genes with fatty acid composition in commercial cross-bred beef steers.

    abstract::Two previously reported non-synonymous coding single nucleotide polymorphisms (SNPs) of bovine stearoyl-CoA desaturase (delta-9-desaturase) (SCD) (c.878C>T) and fatty acid synthase (FASN) (g:17924A>G) were assessed for their associations with 72 individual and 12 groups of fatty acids in brisket adipose tissue of 223 ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2011.02217.x

    authors: Li C,Aldai N,Vinsky M,Dugan ME,McAllister TA

    更新日期:2012-02-01 00:00:00

  • The European sea bass: a key marine fish model in the wild and in aquaculture.

    abstract::The European sea bass (Dicentrarchus labrax L.) is a marine fish of key economic and cultural importance in Europe. It is now more an aquaculture than a fisheries species (>96% of the production in 2016), although modern rearing techniques date back only from the late 1980s. It also has high interest for evolutionary ...

    journal_title:Animal genetics

    pub_type: 杂志文章,评审

    doi:10.1111/age.12779

    authors: Vandeputte M,Gagnaire PA,Allal F

    更新日期:2019-06-01 00:00:00

  • Genome-wide association study confirms that the chromosome Z harbours a region responsible for rumplessness in Hongshan chickens.

    abstract::Rumplessness in Hongshan chickens has been reported as a novel sex-linked characteristic. Re-sequencing data suggest that a pseudogene on the Z chromosome, LOC431648, is affiliated with this phenotype. In this study, we chose 23 rumpless and 25 normal Hongshan chickens to localize the potential variation by means of a...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12664

    authors: Wang Q,Pi J,Shen J,Pan A,Qu L

    更新日期:2018-08-01 00:00:00

  • Characterization of Iberian pig genotypes using AFLP markers.

    abstract::The use of the AFLP (amplified fragment length polymorphism) technique for the characterization of highly inbred Iberian pig breed genotypes and the detection of strain-specific polymorphisms is demonstrated. Twelve different primer combinations were used on individual DNA samples from animals belonging to two black h...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2052.2000.00603.x

    authors: Ovilo C,Cervera MT,Castellanos C,Martínez-Zapater JM

    更新日期:2000-04-01 00:00:00

  • Identification and SNP association analysis of a novel gene in chicken.

    abstract::A novel gene that was predicted to encode a long noncoding RNA (lncRNA) transcript was identified in a previous study that aimed to detect candidate genes related to growth rate differences between Chinese local breed Gushi chickens and Anka broilers. To characterise the biological function of the lncRNA, we cloned an...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12387

    authors: Mei X,Kang X,Liu X,Jia L,Li H,Li Z,Jiang R

    更新日期:2016-02-01 00:00:00

  • Selection signature analysis reveals genes associated with tail type in Chinese indigenous sheep.

    abstract::Fat-tailed sheep have commercial value because consumers prefer high-protein and low-fat food and producers care about feed conversion rate. However, fat-tailed sheep still have some scientific significance, as the fat tail is commonly regarded as a characteristic of environmental adaptability. Finding the candidate g...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12477

    authors: Yuan Z,Liu E,Liu Z,Kijas JW,Zhu C,Hu S,Ma X,Zhang L,Du L,Wang H,Wei C

    更新日期:2017-02-01 00:00:00

  • Cloning, sequencing and linkage mapping of the NRAMP1 gene of sheep and deer.

    abstract::The ovine NRAMP1 and cervine NRAMP1 cDNAs were cloned by RT PCR of RNA derived from macrophage enriched leukocyte preparations. The complete coding and 3' regions were sequenced. Both sheep and deer NRAMP1 proteins are 548 amino acids long. There are 77 and 73 amino acid differences, respectively, compared to the mous...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2052.1998.00224.x

    authors: Matthews GD,Crawford AM

    更新日期:1998-02-01 00:00:00

  • Linkage of the grey coat colour locus to microsatellites on horse chromosome 25.

    abstract::The progressive loss of colour in the hair of grey horses is controlled by a dominantly inherited allele at the Grey locus (GG). In this study, two paternal Quarter Horse (QH) families segregating for the GG allele were genotyped with a set of 101 microsatellite markers spanning the 31 autosomes and the X chromosome. ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2052.2002.00885.x

    authors: Locke MM,Penedo MC,Bricker SJ,Millon LV,Murray JD

    更新日期:2002-10-01 00:00:00

  • Genetic association between bovine NOD2 polymorphisms and infection by Mycobacterium avium subsp. paratuberculosis in Holstein-Friesian cattle.

    abstract::Nucleotide-Binding Oligomerization Domain 2 (NOD2) has been reported to be a candidate gene for Mycobacterium avium subsp. paratuberculosis (MAP) infection in a Bos taurus × Bos indicus mixed breed based on a genetic association with the c.2197T>C single nucleotide polymorphism (SNP). Nevertheless, this SNP has also b...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2010.02055.x

    authors: Ruiz-Larrañaga O,Garrido JM,Iriondo M,Manzano C,Molina E,Koets AP,Rutten VP,Juste RA,Estonba A

    更新日期:2010-12-01 00:00:00

  • From information to understanding: the role of model organism databases in comparative and functional genomics.

    abstract::Data integration is key to functional and comparative genomics because integration allows diverse data types to be evaluated in new contexts. To achieve data integration in a scalable and sensible way, semantic standards are needed, both for naming things (standardized nomenclatures, use of key words) and also for kno...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2006.01475.x

    authors: Bult CJ

    更新日期:2006-08-01 00:00:00

  • Linkage between amylase-1 locus and a major gene for milk fat content in cattle.

    abstract::Linkage between the amylase-1 (Am-1) locus and a quantitative trait locus influencing fat content in milk was studied in offspring from heterozygous sires of the Swedish Red and White dairy breed. The effect on bull breeding values for fat content was estimated as interactions between sire and paternal Am-1 allele usi...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1993.tb00248.x

    authors: Andersson-Eklund L,Rendel J

    更新日期:1993-04-01 00:00:00

  • On measures of association among genetic variables.

    abstract::Systems involving many variables are important in population and quantitative genetics, for example, in multi-trait prediction of breeding values and in exploration of multi-locus associations. We studied departures of the joint distribution of sets of genetic variables from independence. New measures of association b...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2012.02326.x

    authors: Gianola D,Manfredi E,Simianer H

    更新日期:2012-07-01 00:00:00

  • Polymorphism of the pig acetyl-coenzyme A carboxylase alpha gene is associated with fatty acid composition in a Duroc commercial line.

    abstract::Acetyl-coenzyme A carboxylase alpha (ACACA) catalyses the first committed step in the biosynthesis of long-chain fatty acids (FA) by converting acetyl-CoA into malonyl-CoA. In pigs, the ACACA gene maps to a chromosome 12 QTL with important effects on FA composition. In the present study, we have sequenced the coding r...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2009.01854.x

    authors: Gallardo D,Quintanilla R,Varona L,Díaz I,Ramírez O,Pena RN,Amills M

    更新日期:2009-08-01 00:00:00

  • Definition of the USDA103 strain of channel catfish (Ictalurus punctatus).

    abstract::Although there are differences in performance between genetic groups of channel catfish, identification and management of these groups is difficult because catfish strains look alike and individuals cannot be tagged efficiently. Thus, US catfish producers have not been able to objectively identify fish from different ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2007.01586.x

    authors: Waldbieser GC,Wolters WR

    更新日期:2007-04-01 00:00:00

  • IL26 gene inactivation in Equidae.

    abstract::Interleukin-26 (IL26) is a member of the IL10 cytokine family. The IL26 gene is located between two other well-known cytokines genes of this family encoding interferon-gamma (IFNG) and IL22 in an evolutionary conserved gene cluster. In contrast to humans and most other mammals, mice lack a functional Il26 gene. We ana...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12069

    authors: Shakhsi-Niaei M,Drögemüller M,Jagannathan V,Gerber V,Leeb T

    更新日期:2013-12-01 00:00:00

  • Fine mapping of porcine SSC14 QTL and SCD gene effects on fatty acid composition and melting point of fat in a Duroc purebred population.

    abstract::The stearoyl-CoA desaturase (delta-9-desaturase; SCD) gene is a candidate gene for fatty acid composition. It is located on pig SSC14 in a region where quantitative trait loci (QTL) for fatty acid composition were previously detected in a Duroc purebred population. The objective of the present study was to fine map th...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2011.02236.x

    authors: Uemoto Y,Nakano H,Kikuchi T,Sato S,Ishida M,Shibata T,Kadowaki H,Kobayashi E,Suzuki K

    更新日期:2012-04-01 00:00:00

  • Preparation of chromosome-specific paints and complete assignment of chromosomes in the pig flow karyotype.

    abstract::Sorted chromosomes from each of the 20 clusters of the male porcine bivariate flow karyotype were amplified and biotinylated using DOP-PCR. The chromosomes comprising each cluster were identified by fluorescence in situ hybridization (FISH) of the 20 probes to R-banded male pig metaphase spreads. A standard flow karyo...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1993.tb00309.x

    authors: Langford CF,Telenius H,Miller NG,Thomsen PD,Tucker EM

    更新日期:1993-08-01 00:00:00

  • Analysis of genetic relatedness among Indian cattle (Bos indicus) using genotyping-by-sequencing markers.

    abstract::Genetic relatedness of 24 animals belonging to seven Indian cattle breeds was studied using high throughput genotyping-by-sequencing (GBS) markers. GBS produced 93.6 million reads with an average of about 3.9 million reads per animal. A total of 107 488 SNPs were identified in these individuals. When only one SNP per ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12650

    authors: Malik AA,Sharma R,Ahlawat S,Deb R,Negi MS,Tripathi SB

    更新日期:2018-06-01 00:00:00

  • Caecal transcriptome analysis of colonized and non-colonized chickens within two genetic lines that differ in caecal colonization by Campylobacter jejuni.

    abstract::Campylobacter jejuni is one of the most common causes of human bacterial enteritis worldwide. The molecular mechanisms of the host responses of chickens to C. jejuni colonization are not well understood. We have previously found differences in C. jejuni colonization at 7-days post-inoculation (pi) between two genetic ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2010.02168.x

    authors: Li XY,Swaggerty CL,Kogut MH,Chiang HI,Wang Y,Genovese KJ,He H,Pevzner IY,Zhou HJ

    更新日期:2011-10-01 00:00:00

  • Runs of homozygosity: current knowledge and applications in livestock.

    abstract::This review presents a broader approach to the implementation and study of runs of homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH and their practical implications. ROH are continuous homozygous segments that are common in individuals and populations. The ability of these homoz...

    journal_title:Animal genetics

    pub_type: 杂志文章,评审

    doi:10.1111/age.12526

    authors: Peripolli E,Munari DP,Silva MVGB,Lima ALF,Irgang R,Baldi F

    更新日期:2017-06-01 00:00:00

  • Genetic markers applied in regression tree prediction models.

    abstract::Classification and regression tree (CART) modelling was used to determine infectious hypodermal and haematopoietic necrosis virus (IHHNV) resistance and susceptibility in Penaeus stylirostris. In a previous study, eight random amplified polymorphic DNA (RAPD) markers and viral load values using real-time quantitative ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2052.2003.01068.x

    authors: Hizer SE,Wright TM,Garcia DK

    更新日期:2004-02-01 00:00:00

  • Biochemical characterization of the bovine genetic kappa-casein C and E variants.

    abstract::Analysis of elution profiles of enzymatic and CNBr digests of kappa-caseins C and E, and sequencing of most relevant peptides allowed the chemical characterization of both genetic variants. They differ from their B and A allelic counterparts by a single substitution, His97/Arg and Gly155/Ser, respectively. Electrophor...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1993.tb00915.x

    authors: Miranda G,Anglade P,Mahé MF,Erhardt G

    更新日期:1993-02-01 00:00:00

  • A partial cDNA clone for porcine glucosephosphate isomerase: isolation, characterization and use in detection of restriction fragment length polymorphisms.

    abstract::A cDNA library for porcine skeletal muscle was established in the vector pBR322. The library was screened with an oligonucleotide probe coding for a hexapeptide from glucosephosphate isomerase (Gpi). A positive clone with an insert of about 450 bp and restriction sites for PstI, BamHI and PvuII was isolated. A 362-bp ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1987.tb00763.x

    authors: Davies W,Harbitz I,Hauge JG

    更新日期:1987-01-01 00:00:00

  • Association between population structure and allele frequencies of the glycogen synthase 1 mutation in the Austrian Noriker draft horse.

    abstract::The aim of this study was to determine the allele frequency of the glycogen synthase 1 (GYS1) mutation associated with polysaccharide storage myopathy type 1 in the Austrian Noriker horse. Furthermore, we examined the influence of population substructures on the allele distribution. The study was based upon a comprehe...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12481

    authors: Druml T,Grilz-Seger G,Neuditschko M,Brem G

    更新日期:2017-02-01 00:00:00

  • Comparing two commercial domestic dog (Canis familiaris) STR genotyping kits for forensic identity calculations in a mixed-breed dog population sample.

    abstract::Almost half of all US households own a dog (Canis familiaris). Though these household pets can attack humans and other animals, they are also frequently victims of cruelty, neglect and theft. In human-oriented investigations, the tendency of domestic dogs to leave behind physical traces (such as hair) can serve as val...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12758

    authors: Kanthaswamy S,Oldt RF,Montes M,Falak A

    更新日期:2019-02-01 00:00:00

  • Mapping of expressed sequence tags from a porcine early embryonic cDNA library.

    abstract::The goal of this study was to identify and map genes expressed during the elongation phase of embryogenesis in swine. Expressed sequence tags were analysed from a previously described porcine cDNA library prepared from elongating swine embryos. Average insert length of randomly selected clones was approximately 600 bp...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2052.2001.00739.x

    authors: Smith TP,Fahrenkrug SC,Rohrer GA,Simmen FA,Rexroad CE,Keele JW

    更新日期:2001-04-01 00:00:00

  • Direct sequencing and bidirectional allele specific polymerase chain reaction of the bovine beta-casein B variant.

    abstract::We have used the polymerase chain reaction (PCR) to amplify exon VII of the bovine beta-casein gene. The mutations responsible for the B variant were identified by direct sequencing of the amplification products. A bidirectional allele-specific PCR method (BAS-PCR) has been developed using oligonucleotides overlapping...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1992.tb00180.x

    authors: Damiani G,Pilla F,Leone P,Cacciò S

    更新日期:1992-01-01 00:00:00