QTL detection on porcine chromosome 12 for fatty-acid composition and association analyses of the fatty acid synthase, gastric inhibitory polypeptide and acetyl-coenzyme A carboxylase alpha genes.

abstract：:Swiss Fleckvieh was established in 1970 as a composite of Simmental (SI) and Red Holstein Friesian (RHF) cattle. Breed composition is currently reported based on pedigree information. Information on a large number of molecular markers potentially provides more accurate information. For the analysis, we used Illumina B...

journal_title：Animal genetics

authors： Frkonja A,Gredler B,Schnyder U,Curik I,Sölkner J

更新日期：2012-12-01 00:00:00

abstract：:Sorted chromosomes from each of the 20 clusters of the male porcine bivariate flow karyotype were amplified and biotinylated using DOP-PCR. The chromosomes comprising each cluster were identified by fluorescence in situ hybridization (FISH) of the 20 probes to R-banded male pig metaphase spreads. A standard flow karyo...

journal_title：Animal genetics

authors： Langford CF,Telenius H,Miller NG,Thomsen PD,Tucker EM

更新日期：1993-08-01 00:00:00

abstract：:A feral donkey population (Equus asinus), living in the Asinara National Park (an island north-west of Sardinia, Italy), includes a unique white albino donkey subpopulation or colour morph that is a major attraction of this park. Disrupting mutations in the tyrosinase (TYR) gene are known to cause recessive albinisms ...

journal_title：Animal genetics

authors： Utzeri VJ,Bertolini F,Ribani A,Schiavo G,Dall'Olio S,Fontanesi L

更新日期：2016-02-01 00:00:00

abstract：:Among all livestock species, cattle have a prominent status as they have contributed greatly to the economy, nutrition and culture from the beginning of farming societies until the present time. The origins and diversity of local cattle breeds have been widely assessed. However, there are still some regions for which ...

journal_title：Animal genetics

authors： Mahgoub O,Babiker HA,Kadim IT,Al-Kindi M,Hassan S,Al-Marzooqi W,Eltahir YE,Al-Abri MA,Al-Khayat A,Al-Sinani KR,Hilal Al-Khanjari H,Costa V,Chen S,Beja-Pereira A

更新日期：2013-06-01 00:00:00

abstract：:Recurrent airway obstruction (RAO) in horses is the result of an interaction of genetic and environmental factors and shares many characteristics with human asthma. Many studies have suggested that the interleukin-4 receptor gene (IL4R) is associated with this disease, and a QTL region on chromosome 13 containing IL4R...

journal_title：Animal genetics

authors： Klukowska-Rötzler J,Swinburne JE,Drögemüller C,Dolf G,Janda J,Leeb T,Gerber V

更新日期：2012-08-01 00:00:00

abstract：:Loss-of-function variants in the MC1R gene cause recessive red or yellow coat-colour phenotypes in many species. The canine MC1R:c.916C>T (p.Arg306Ter) variant is widespread and found in a homozygous state in many uniformly yellow- or red-coloured dogs. We investigated cream-coloured Australian Cattle Dogs whose coat ...

journal_title：Animal genetics

authors： Dürig N,Letko A,Lepori V,Hadji Rasouliha S,Loechel R,Kehl A,Hytönen MK,Lohi H,Mauri N,Dietrich J,Wiedmer M,Drögemüller M,Jagannathan V,Schmutz SM,Leeb T

更新日期：2018-08-01 00:00:00

abstract：:The Third International Workshop on Lymphocyte Alloantigens of the Horse was held on 25-27 April 1984 in Kennett Square, Pennsylvania. Twelve laboratories from five countries participated. The principal purpose of this Workshop was to determine the phenotypic and gene frequencies of the 10 equine lymphocyte antigens (...

journal_title：Animal genetics

authors： Antczak DF,Bailey E,Barger B,Guerin G,Lazary S,McClure J,Mottironi VD,Symons R,Templeton J,Varewyck H

更新日期：1986-01-01 00:00:00

abstract：:A map of the ovine MHC class II DQ subregion has been constructed from overlapping cosmid clones. This region consists of two loci linked on a linear tract of 130 kb DNA. Each locus consists of a DQA and a DQB gene in a tail-to-tail orientation. The genes in each locus are transcribed but only those designated DQ1 exp...

journal_title：Animal genetics

authors： Wright H,Ballingall KT

更新日期：1994-08-01 00:00:00

abstract：:Two cDNA probes for the porcine calcium release channel gene (CRC) were used in restriction fragment length polymorphism (RFLP) analysis in an attempt to develop genetic markers linked to the malignant hyperthermia (stress susceptibility) gene (HAL). Three TaqI RFLPs, denoted CRC1-CRC3, each composed of two alleles, w...

journal_title：Animal genetics

authors： Mariani P,Johansson M,Ellegren H,Harbitz I,Juneja RK,Andersson L

更新日期：1992-01-01 00:00:00

abstract：:In order to obtain monoclonal alloantibodies against bovine blood group antigens, lymph node cells from calves immunized with bovine red blood cells (RBC) were fused with either murine NSO/1 myeloma cells or a HAT sensitive murine x bovine heterohybridoma cell line. Both fusion partners resulted in heterohybridoma cel...

journal_title：Animal genetics

authors： Hønberg LS,Larsen B

更新日期：1992-01-01 00:00:00

abstract：:Glutaminyl-peptide cyclotransferase-like (QPCTL) is an isoenzyme of glutaminyl-peptide cyclotransferase (QPCT). QPCTL and QPCT catalyze the formation of N-terminal modified pyroglutamate-fractalkine and the chemokine CCL2. The objective of this study was to investigate the association between insertions/deletions in t...

journal_title：Animal genetics

authors： Ren T,Li W,Liu D,Liang K,Wang X,Li H,Jiang R,Tian Y,Kang X,Li Z

更新日期：2019-06-01 00:00:00

abstract：:We determined the genetic diversity and evolutionary relationships among 26 Chinese indigenous horse breeds and two introduced horse breeds by genotyping these animals for 27 microsatellite loci. The 26 Chinese horse breeds come from 12 different provinces. Two introduced horse breeds were the Mongolia B Horse from Mo...

journal_title：Animal genetics

authors： Ling YH,Ma YH,Guan WJ,Cheng YJ,Wang YP,Han JL,Mang L,Zhao QJ,He XH,Pu YB,Fu BL

更新日期：2011-02-01 00:00:00

abstract：:The melanocortin-4 receptor (MC4R), a G-protein coupled receptor, is implicated in mediating the effect of leptin on food intake and energy balance. A previous candidate gene study reported an association between an MC4R missense mutation (Asp298Asn) and fatness, growth and feed intake in pigs. To assess this associat...

journal_title：Animal genetics

authors： Park HB,Carlborg O,Marklund S,Andersson L

更新日期：2002-04-01 00:00:00

abstract：:RNA editing is a post-transcription maturation process that diversifies genomically encoded information and can lead to transcriptome diversity. Thanks to next-generation sequencing technologies, a large number of editing sites have been identified in different species. Although this mechanism is well described in mam...

journal_title：Animal genetics

authors： Shafiei H,Bakhtiarizadeh MR,Salehi A

更新日期：2019-10-01 00:00:00

abstract：:Genetic differences which exist in the prion protein gene (PRNP) have been reported to influence susceptibility of humans, sheep and goats to prion diseases. In cattle, however, none of the known coding polymorphisms has a direct effect on bovine spongiform encephalopathy (BSE). It has been reported that 23-bp inserti...

journal_title：Animal genetics

authors： Msalya G,Shimogiri T,Nishitani K,Okamoto S,Kawabe K,Minesawa M,Maeda Y

更新日期：2010-04-01 00:00:00

abstract：:MicroRNA (miRNA) biogenesis is determined mainly by Drosha, Dicer and Argonaute2 (Ago2). Different breeds of pigs with vast differences in serum cortisol level demonstrate distinct profiles of hepatic miRNA expression. As yet, little is known about whether glucocorticoid contributes to the breed differences in miRNA b...

journal_title：Animal genetics

authors： Li R,Jia Y,Zou H,Zhao R

更新日期：2014-12-01 00:00:00

abstract：:An MspI polymorphism was identified in intron 13 of the equine homologue of proto-oncogene c-kit (KIT) by comparing DNA sequences from horses with solid coat colour and horses homozygous for the tobiano spotting (To) gene. The allele associated with solid coat colour was designated KM0, while the allele associated wit...

journal_title：Animal genetics

authors： Brooks SA,Terry RB,Bailey E

更新日期：2002-08-01 00:00:00

abstract：:A genetic disease observed in certain Quarter horses is hyperkalaemic periodic paralysis (HYPP). This disease causes attacks of paralysis which can be induced by ingestion of potassium. Recent studies have shown that HYPP in humans is due to single base changes within the adult skeletal muscle sodium channel gene. A l...

journal_title：Animal genetics

authors： Rudolph JA,Spier SJ,Byrns G,Hoffman EP

更新日期：1992-01-01 00:00:00

abstract：:In the present study, data from four F2 crosses were analysed and used to study the linkage disequilibrium (LD) structure within and across the crosses. Genome-wide association analyses (GWASes) for conductivity and dressing out meat traits were conducted using single-marker and Bayesian multi-marker models using the ...

journal_title：Animal genetics

authors： Stratz P,Schmid M,Wellmann R,Preuß S,Blaj I,Tetens J,Thaller G,Bennewitz J

更新日期：2018-10-01 00:00:00

abstract：:Acetyl-coenzyme A carboxylase alpha (ACACA) catalyses the first committed step in the biosynthesis of long-chain fatty acids (FA) by converting acetyl-CoA into malonyl-CoA. In pigs, the ACACA gene maps to a chromosome 12 QTL with important effects on FA composition. In the present study, we have sequenced the coding r...

journal_title：Animal genetics

authors： Gallardo D,Quintanilla R,Varona L,Díaz I,Ramírez O,Pena RN,Amills M

更新日期：2009-08-01 00:00:00

abstract：:cDNAs encoding porcine beta-lactoglobulin were isolated and sequenced. The porcine beta-lactoglobulin cDNA is 768bp in length and encodes a pre-protein of 178 amino acids. One additional cDNA clone was found to encode an additional amino acid (lysine) in the mature protein. ...

journal_title：Animal genetics

authors： Alexander LJ,Beattie CW

更新日期：1992-01-01 00:00:00

abstract：:A comparative transcription analysis of Ig κ-light chains (IGK) of the cattle breeds Holstein Friesian (HF), German Black Pied (GBP), German Simmental (GS) and Aubrac (A) revealed three alleles coding for two putative allotypic variants of IGKC. The amino acid residues p.Asp100Asn and p.Thr116Ala were located at the o...

journal_title：Animal genetics

authors： Stein SK,Diesterbeck US,Aboelhassan DM,Czerny CP

更新日期：2012-12-01 00:00:00

abstract：:A canine blood group antigen, QN, which was detected by a naturally occurring alloantibody in the antiglobulin test, was shown to be antigenically related to the human A and cattle J antigens by absorption experiments. Family studies supported a dominant mode of inheritance with the gene controlling the production of ...

journal_title：Animal genetics

authors： Symons M,Bell K

更新日期：1992-01-01 00:00:00

abstract：:A high-resolution comprehensive map was constructed for porcine chromosome (SSC) 6, where quantitative trait loci (QTL) for reproduction and meat quality traits have been reported to exist. A radiation hybrid (RH) map containing 105 gene-based markers and 15 microsatellite markers was constructed for this chromosome u...

journal_title：Animal genetics

authors： Cao H,Robinson JA,Jiang Z,Melville JS,Golovan SP,Jones MW,Verrinder Gibbins AM

更新日期：2004-10-01 00:00:00

abstract：:The bacterial artificial clone-based physical map for chicken plays an important role in the integration of the consensus linkage map and the whole-genome shotgun sequence. It also provides a valuable resource for clone selection within applications such as fluorescent in situ hybridization and positional cloning. How...

journal_title：Animal genetics

authors： Aerts JA,Veenendaal T,van der Poel JJ,Crooijmans RP,Groenen MA

更新日期：2005-06-01 00:00:00

abstract：:We present herein a bovine chromosome 24 (BTA24) radiation hybrid (RH) map using 40 markers scored on a panel of 90 RHs. Of these markers, 29 loci were ordered with odds of at least 1000:1 in a framework map. An average retention frequency of 17.4% was observed, with relatively higher frequencies near the centromere. ...

journal_title：Animal genetics

authors： Kurar E,Womack JE,Kirkpatrick BW

更新日期：2003-06-01 00:00:00

abstract：:Many genomic methodologies rely on the presence and extent of linkage disequilibrium (LD) between markers and genetic variants underlying traits of interest, but the extent of LD in the horse has yet to be comprehensively characterized. In this study, we evaluate the extent and decay of LD in a sample of 817 Thoroughb...

journal_title：Animal genetics

authors： Corbin LJ,Blott SC,Swinburne JE,Vaudin M,Bishop SC,Woolliams JA

更新日期：2010-12-01 00:00:00

abstract：:Novel and traditional eggshell quality measurements were made from up to 2000 commercial pedigree hens for a candidate gene association analysis with organic eggshell matrix genes: ovocleidin-116, osteopontin (SPP1), ovocalyxin-32 (RARRES1), ovotransferrin (LTF), ovalbumin and ovocalyxin-36, as well as key genes in th...

journal_title：Animal genetics

authors： Dunn IC,Joseph NT,Bain M,Edmond A,Wilson PW,Milona P,Nys Y,Gautron J,Schmutz M,Preisinger R,Waddington D

更新日期：2009-02-01 00:00:00

abstract：:The amplified fragment length polymorphism (AFLP) technique has been used to enhance marker density in the East Lansing reference chicken genome map, using a backcross family derived from a Red Jungle Fowl by White Leghorn mating with White Leghorn as the recurrent parent. To date, 204 AFLP markers have been added, ex...

journal_title：Animal genetics

authors： Knorr C,Cheng HH,Dodgson JB

更新日期：1999-02-01 00:00:00

abstract：:Genotype imputation facilitates the identification of missing genotypes on a high-density array using low-density arrays and has great potential for reducing genotyping costs for cattle populations. However, the imputation quality varies across breeds, which have different effective population sizes. Therefore, the ac...

journal_title：Animal genetics

authors： Uemoto Y,Sasaki S,Sugimoto Y,Watanabe T

更新日期：2015-08-01 00:00:00