Abstract:
:A canine blood group antigen, QN, which was detected by a naturally occurring alloantibody in the antiglobulin test, was shown to be antigenically related to the human A and cattle J antigens by absorption experiments. Family studies supported a dominant mode of inheritance with the gene controlling the production of QN being dominant to the gene responsible for its absence. Frequencies of the QN and Tr antigens and serological data strongly suggested that the two antigens are identical. Two canine plasma alkaline phosphatase variants, F and S, were detected by starch gel electrophoresis, pH 8.65. Assuming genetic control of two codominant alleles, ALPF and ALPS, the distributions of types in families differed significantly from expectation. A relationship between the ALP and Tr(QN) systems was demonstrated with Tr-positive animals having a significant deficiency of S alkaline phosphatase types.
journal_name
Anim Genetjournal_title
Animal geneticsauthors
Symons M,Bell Kdoi
10.1111/j.1365-2052.1992.tb00153.xsubject
Has Abstractpub_date
1992-01-01 00:00:00pages
315-24issue
4eissn
0268-9146issn
1365-2052journal_volume
23pub_type
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