Molecular characterization of the human ABO blood group orthologus system in pigs.

Abstract:

:The selection and use of animals with blood group 0 in the process of transplanting pig organs or tissues into humans can positively contribute to the control of acute immune rejection due to differences in blood groups. Exon-specific PCRs for the porcine blood group A transferase gene against genomic DNA from either blood group A or 0 animals resulted in the amplification failure of the A0 blood group gene exon 8 from blood group 0 animals. To characterize the genetic abnormality in the genome of blood group 0 animals, we screened bacterial artificial chromosome (BAC) clones from a Korean native pig BAC library which had the blood group 0 allele, and carried out shotgun sequencing. The analysis showed that the 0 allele has a large deletion between exon 7 of the A0 blood group gene and the neighbouring SURF6. We also showed that the ABO blood group antigens in humans and the A0 blood group antigens in pigs are coded by mutations within the orthologous glycosyltransferase gene. In addition, we developed a multiplex genotyping method for the porcine A0 blood group gene.

journal_name

Anim Genet

journal_title

Animal genetics

authors

Nguyen DT,Choi H,Jo H,Kim JH,Dirisala VR,Lee KT,Kim TH,Park KK,Seo K,Park C

doi

10.1111/j.1365-2052.2010.02152.x

subject

Has Abstract

pub_date

2011-06-01 00:00:00

pages

325-8

issue

3

eissn

0268-9146

issn

1365-2052

journal_volume

42

pub_type

杂志文章
  • Association analysis of adiponectin and somatostatin polymorphisms on BTA1 with growth and carcass traits in Angus cattle.

    abstract::This study tested positional candidate genes adiponectin (ADIPOQ) and somatostatin (SST) for effects on carcass traits in a commercially relevant cattle population. Both genes are located within a region of BTA1 previously reported to harbour quantitative trait loci (QTL) that affect marbling, quality grade, yield gra...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2006.01528.x

    authors: Morsci NS,Schnabel RD,Taylor JF

    更新日期:2006-12-01 00:00:00

  • Genetic variation within and among domesticated Atlantic salmon broodstocks in British Columbia, Canada.

    abstract::Atlantic salmon have been reared in the British Columbia, Canada aquaculture industry since the early 1980s. No breeding programmes spanned the entire production period and pedigree records were not kept for broodstocks prior to or since importation. Of the three recognized industry strains, two are of European ancest...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2004.01220.x

    authors: Withler RE,Supernault KJ,Miller KM

    更新日期:2005-02-01 00:00:00

  • SNP detection and genetic mapping of porcine genes encoding enzymes in hepatic metabolic pathways and evaluation of linkage with carcass traits.

    abstract::We have previously identified and mapped porcine expressed sequence tags (ESTs) derived from genes that are preferentially expressed in liver. The aim of the present study was to identify single nucleotide polymorphisms (SNPs) in porcine genes encoding enzymes in hepatic metabolic pathways and use the SNPs for mapping...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2005.01351.x

    authors: Ponsuksili S,Chomdej S,Murani E,Bläser U,Schreinemachers HJ,Schellander K,Wimmers K

    更新日期:2005-12-01 00:00:00

  • Genomic prediction of reproduction traits for Merino sheep.

    abstract::Economically important reproduction traits in sheep, such as number of lambs weaned and litter size, are expressed only in females and later in life after most selection decisions are made, which makes them ideal candidates for genomic selection. Accurate genomic predictions would lead to greater genetic gain for thes...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12541

    authors: Bolormaa S,Brown DJ,Swan AA,van der Werf JHJ,Hayes BJ,Daetwyler HD

    更新日期:2017-06-01 00:00:00

  • Twenty years of artificial directional selection have shaped the genome of the Italian Large White pig breed.

    abstract::In this study, we investigated at the genome-wide level if 20 years of artificial directional selection based on boar genetic evaluation obtained with a classical BLUP animal model shaped the genome of the Italian Large White pig breed. The most influential boars of this breed (n = 192), born from 1992 (the beginning ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12392

    authors: Schiavo G,Galimberti G,Calò DG,Samorè AB,Bertolini F,Russo V,Gallo M,Buttazzoni L,Fontanesi L

    更新日期:2016-04-01 00:00:00

  • Significant association between SNPs in the superoxide dismutase 3, extracellular (SOD3) gene and resistance to Aeromonas hydrophila in the freshwater mussel Hyriopsis cumingii.

    abstract::Extracellular superoxide dismutase (SOD3) is a major antioxidant enzyme that protects organs from damage by reactive oxygen species (ROS). In this study, the SOD3 gene was identified and characterized from the freshwater mussel Hyriopsis cumingii (Hc-SOD3). The cDNA sequence consists of 763 bp, encoding a protein of 2...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12059

    authors: Wang GL,Li XL,Li JL

    更新日期:2013-12-01 00:00:00

  • Extending the chicken-human comparative map by placing 15 genes on the chicken linkage map.

    abstract::To increase the number of type I loci on the chicken linkage map, chicken genes containing microsatellite sequences (TAn, CAn, GAn, An) were selected from the nucleotide sequence database and primers were developed to amplify the repeats. Initially, 40 different microsatellites located within genes were tested on a pa...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2052.1999.00527.x

    authors: Groenen MA,Crooijmans RP,Dijkhof RJ,Acar R,van der Poel JJ

    更新日期:1999-12-01 00:00:00

  • Quantitative trait loci for litter size and prenatal loss in a White Duroc x Chinese Erhualian resource population.

    abstract::To detect quantitative trait loci (QTL) for litter size related traits, the total number of born piglets (TNB), the number of born alive piglets (NBA), the number of stillborn piglets (NSB) and the number of mummies (NM) at the first parity were recorded in 299 F(2) sows in a White Duroc x Chinese Erhualian intercross...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2009.01931.x

    authors: Li K,Ren J,Xing Y,Zhang Z,Ma J,Guo Y,Huang L

    更新日期:2009-12-01 00:00:00

  • Single nucleotide polymorphism discovery in albacore and Atlantic bluefin tuna provides insights into worldwide population structure.

    abstract::The optimal management of the commercially important, but mostly over-exploited, pelagic tunas, albacore (Thunnus alalunga Bonn., 1788) and Atlantic bluefin tuna (BFT; Thunnus thynnus L., 1758), requires a better understanding of population structure than has been provided by previous molecular methods. Despite numero...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12051

    authors: Albaina A,Iriondo M,Velado I,Laconcha U,Zarraonaindia I,Arrizabalaga H,Pardo MA,Lutcavage M,Grant WS,Estonba A

    更新日期:2013-12-01 00:00:00

  • Transcriptome analysis of the endometrium from Chinese Erhualian sows that differ in calcium ion concentration and litter size.

    abstract::Embryonic survival rate, an important factor in the fecundity of sows, is affected by endometrium-secreting histotroph. A higher concentration of calcium ion has been observed in the uterus of highly prolific Erhualian sows (EH) compared with those of less prolific (EL) sows. This suggests that EH sows have better est...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12788

    authors: Ma X,Li P,Zhang Q,He L,Su G,Huang Y,Lu Z,Hu W,Ding H,Huang R

    更新日期:2019-08-01 00:00:00

  • Novel alternative splicing by exon skipping in KIT associated with whole-body roan in an intercrossed population of Landrace and Korean Native pigs.

    abstract::The KIT locus has been suggested to be a strong candidate region linked with whole-body roan in the F(2) population produced by intercrosses between Landrace and Korean Native pigs. In this manuscript, we report the finding of a novel alternative splicing event in the porcine KIT gene that results in the skipping of e...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2011.02225.x

    authors: Lim HT,Zhong T,Cho IC,Seo BY,Kim JH,Lee SS,Ko MS,Park HB,Kim BW,Lee JH,Jeon JT

    更新日期:2011-08-01 00:00:00

  • Mapping of quantitative trait loci controlling tick [Riphicephalus (Boophilus) microplus] resistance on bovine chromosomes 5, 7 and 14.

    abstract::Differences in domestication and selection processes have contributed to considerable phenotypic and genotypic differences between Bos taurus and Bos indicus cattle breeds. Of particular interest in tropical and subtropical production environments are those genetic differences between subspecies that underlie the phen...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2007.01634.x

    authors: Gasparin G,Miyata M,Coutinho LL,Martinez ML,Teodoro RL,Furlong J,Machado MA,Silva MV,Sonstegard TS,Regitano LC

    更新日期:2007-10-01 00:00:00

  • Detection of copy number variants in the horse genome and examination of their association with recurrent laryngeal neuropathy.

    abstract::We used the data from a recently performed genome-wide association study using the Illumina Equine SNP50 beadchip for the detection of copy number variants (CNVs) and examined their association with recurrent laryngeal neuropathy (RLN), an important equine upper airway disease compromising performance. A total of 2797...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2012.02373.x

    authors: Dupuis MC,Zhang Z,Durkin K,Charlier C,Lekeux P,Georges M

    更新日期:2013-04-01 00:00:00

  • Identification of a premature stop codon in the melanocyte-stimulating hormone receptor gene (MC1R) in Labrador and Golden retrievers with yellow coat colour.

    abstract::We have examined whether black/yellow coat colour in Labrador retrievers is controlled by allelic variants at the extension locus. As the gene encoding the melanocyte-stimulating hormone receptor (MC1R) has been shown to correspond to the extension locus in several species, we have determined the genomic MC1R sequence...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2052.2000.00639.x

    authors: Everts RE,Rothuizen J,van Oost BA

    更新日期:2000-06-01 00:00:00

  • Maternity validation using sire-only BovineSNP50 BeadChip data.

    abstract::Based on pairwise identity-by-state (IBS) distances and whole-genome SNP data, kinship was investigated in the Israeli Holstein population. A total of 789 bulls, including most of the artificial insemination sires in service since 1987, were genotyped by the BovineSNP50 BeadChip. This sample included up to five genera...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12062

    authors: Seroussi E,Glick G,Shirak A,Ezra E,Zeron Y,Ron M,Weller JI

    更新日期:2013-12-01 00:00:00

  • Linkage disequilibrium over short physical distances measured in sheep using a high-density SNP chip.

    abstract::The extent of linkage disequilibrium (LD) between genetic loci has implications for both association studies and the accuracy of genomic prediction. To characterise the persistence of LD in diverse sheep breeds, two SNP genotyping platforms were used. First, existing SNP genotypes from 63 breeds obtained using the ovi...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12197

    authors: Kijas JW,Porto-Neto L,Dominik S,Reverter A,Bunch R,McCulloch R,Hayes BJ,Brauning R,McEwan J,International Sheep Genomics Consortium.

    更新日期:2014-10-01 00:00:00

  • Microphthalmia-associated transcription factor mutations are associated with white-spotted coat color in swamp buffalo.

    abstract::A candidate gene analysis of the microphthalmia-associated transcription factor (MITF) gene was used in an attempt to identify the genetic basis for a white-spotted coat color phenotype in the Asian swamp buffalo (Bubalus bubalis carabanensis). Ninety-three buffaloes-32 solid, 38 spotted and 23 white individuals-were ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12334

    authors: Yusnizar Y,Wilbe M,Herlino AO,Sumantri C,Noor RR,Boediono A,Andersson L,Andersson G

    更新日期:2015-12-01 00:00:00

  • Phylogenetic analysis of Sicilian goats reveals a new mtDNA lineage.

    abstract::The mitochondrial hypervariable region 1 (HVR1) sequence of 67 goats belonging to the Girgentana, Maltese and Derivata di Siria breeds was partially sequenced in order to present the first phylogenetic characterization of Sicilian goat breeds. These sequences were compared with published sequences of Indian and Pakist...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2006.01451.x

    authors: Sardina MT,Ballester M,Marmi J,Finocchiaro R,van Kaam JB,Portolano B,Folch JM

    更新日期:2006-08-01 00:00:00

  • Genetic polymorphism of the sixth component of complement (C6) in dogs.

    abstract::Using agarose gel isoelectric focusing and immunoblotting with rabbit anti-rabbit C6, a genetic polymorphism was found in the sixth component of complement (C6) in 18 Asian native breeds or populations and three European breeds of dog. The C6 locus was highly polymorphic. The phenotype distribution data indicated that...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1995.tb02641.x

    authors: Shibata T,Abe T,Tanabe Y

    更新日期:1995-04-01 00:00:00

  • Identification of a short interspersed repetitive element insertion polymorphism in the porcine MX1 promoter associated with resistance to porcine reproductive and respiratory syndrome virus infection.

    abstract::The myxovirus resistance (Mx) proteins belong to the dynamin superfamily and are important for innate host defence against RNA viruses. In this study, we demonstrate that positive elements are present in the two promoter regions of -2713 to -2565 and -688 to -431 in the porcine MX1 gene. Sequencing and alignment of th...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12316

    authors: Li Y,Liang S,Liu H,Sun Y,Kang L,Jiang Y

    更新日期:2015-08-01 00:00:00

  • Parentage testing of dogs using variants of blood proteins: description of five new plasma protein polymorphisms.

    abstract::Plasma samples of 1126 dogs belonging to 21 different European breeds were analysed by two-dimensional agarose gel (pH 5.4 or pH 8.6)--horizontal polyacrylamide gel (pH 9.0) electrophoresis, followed by general-protein staining of gels. Genetic polymorphism was detected for five as yet unidentified proteins designated...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1987.tb00773.x

    authors: Juneja RK,Arnold IC,Gahne B,Bouw J

    更新日期:1987-01-01 00:00:00

  • A genome-wide association study for the number of teats in European rabbits (Oryctolagus cuniculus) identifies several candidate genes affecting this trait.

    abstract::In the European rabbit (Oryctolagus cuniculus), a polytocous livestock species, the number of teats indirectly impacts the doe reproduction efficiency and, in turn, the sustainable production of rabbit meat. In this study, we carried out a genome-wide association study (GWAS) for the total number of teats in 247 Itali...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.13036

    authors: Bovo S,Schiavo G,Utzeri VJ,Ribani A,Schiavitto M,Buttazzoni L,Negrini R,Fontanesi L

    更新日期:2021-01-11 00:00:00

  • Evidence for pleiotropism and recent selection in the PLAG1 region in Australian Beef cattle.

    abstract::A putative functional mutation (rs109231213) near PLAG1 (BTA14) associated with stature was studied in beef cattle. Data from 8199 Bos taurus, Bos indicus and Tropical Composite cattle were used to test the associations between rs109231213 and various phenotypes. Further, 23 496 SNPs located on BTA14 were tested for a...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12075

    authors: Fortes MR,Kemper K,Sasazaki S,Reverter A,Pryce JE,Barendse W,Bunch R,McCulloch R,Harrison B,Bolormaa S,Zhang YD,Hawken RJ,Goddard ME,Lehnert SA

    更新日期:2013-12-01 00:00:00

  • A search for associations between major histocompatibility complex restriction fragment length polymorphism bands and resistance to Haemonchus contortus infection in sheep.

    abstract::Polymorphic bands were detected within the DQB and DRB regions of the ovine major histocompatibility complex by probing TaqI digested DNA from three large sheep half-sib families derived from a highly resistant ram. All animals were phenotypically assessed for Haemonchus contortus resistance by faecal egg counts and a...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1993.tb00311.x

    authors: Blattman AN,Hulme DJ,Kinghorn BP,Woolaston RR,Gray GD,Beh KJ

    更新日期:1993-08-01 00:00:00

  • The European sea bass: a key marine fish model in the wild and in aquaculture.

    abstract::The European sea bass (Dicentrarchus labrax L.) is a marine fish of key economic and cultural importance in Europe. It is now more an aquaculture than a fisheries species (>96% of the production in 2016), although modern rearing techniques date back only from the late 1980s. It also has high interest for evolutionary ...

    journal_title:Animal genetics

    pub_type: 杂志文章,评审

    doi:10.1111/age.12779

    authors: Vandeputte M,Gagnaire PA,Allal F

    更新日期:2019-06-01 00:00:00

  • Albinism in the American mink (Neovison vison) is associated with a tyrosinase nonsense mutation.

    abstract::Albino phenotypes are documented in various species including the American mink. In other species the albino phenotypes are associated with tyrosinase (TYR) gene mutations; therefore TYR was considered the candidate gene for albinism in mink. Four microsatellite markers were chosen in the predicted region of the TYR g...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2008.01788.x

    authors: Anistoroaei R,Fredholm M,Christensen K,Leeb T

    更新日期:2008-12-01 00:00:00

  • Restriction fragment length polymorphisms for growth hormone, prolactin, osteonectin, alpha crystallin, gamma crystallin, fibronectin and 21-steroid hydroxylase in cattle.

    abstract::Genomic DNAs from animals representing six breeds of cattle (Angus, Brahman, Hereford, Holstein, Jersey and Texas Longhorn) were screened with cloned gene probes in a search for restriction fragment length polymorphisms (RFLPs). Eleven RFLPs were identified using seven different probes: growth hormone, prolactin, oste...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1989.tb00866.x

    authors: Theilmann JL,Skow LC,Baker JF,Womack JE

    更新日期:1989-01-01 00:00:00

  • Recombination rates and gene order for some serum alpha-protease inhibitors and immunoglobulin heavy-chain allotypes in pigs.

    abstract::Linkage analysis between the genes coding for immunoglobulin heavy-chain allotypes and variants of some serum alpha-protease inhibitors produced lod scores above the significance limit of 3. The maximum likelihood estimate of the recombination fraction (theta) ranged from 0.15 to 0.20. Since this is the second report ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1987.tb00779.x

    authors: Vögeli P,Kühne R,Wysshaar M,Stranzinger G

    更新日期:1987-01-01 00:00:00

  • Biochemical genetic variants in mice selectively bred for sensitivity or resistance to ethanol-induced sedation.

    abstract::The distribution of biochemical genetic variants was examined among eight inbred strains of mice, which served as contributors to a heterogeneous stock of mice (HS), and in short-sleep (SS) and long-sleep (LS) mice, selectively bred from the HS stock for differential ethanol sensitivity. Fifteen loci for enzymes of al...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1986.tb03195.x

    authors: Holmes RS,Petersen DR,Deitrich RA

    更新日期:1986-01-01 00:00:00

  • A QTL affecting milk yield and composition maps to bovine chromosome 20: a confirmation.

    abstract::As part of a whole genome scan undertaken to detect quantitative trait loci (QTL) affecting milk yield and composition, we have genotyped a granddaughter design comprising 1152 sons for six microsatellite markers spanning bovine chromosome 20. An analysis performed across families provided strong evidence (experiment-...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2052.1998.00307.x

    authors: Arranz JJ,Coppieters W,Berzi P,Cambisano N,Grisart B,Karim L,Marcq F,Moreau L,Mezer C,Riquet J,Simon P,Vanmanshoven P,Wagenaar D,Georges M

    更新日期:1998-04-01 00:00:00