Non-replication of genome-wide-based associations of efficient food conversion in dairy cows.

Abstract:

:Animal growth relative to food energy input is of key importance to agricultural production. Several recent studies highlighted genetic markers associated with food conversion efficiency in beef cattle, and there is now a requirement to validate these associations in additional populations and to assess their potential utility for selecting animals with enhanced food-use efficiency. The current analysis tested a population of dairy cattle using 138 DNA markers previously associated with food intake and growth in a whole-genome association analysis of beef animals. Although seven markers showed point-wise significance at P < 0.05, none of the single-nucleotide polymorphisms tested were significantly associated with food conversion efficiency after correction for multiple testing. These data do not support the involvement of this subset of previously implicated markers in the food conversion efficiency of the physiologically distinct New Zealand Holstein-Friesian dairy breed.

journal_name

Anim Genet

journal_title

Animal genetics

authors

Littlejohn M,Grala T,Sanders K,Walker C,Waghorn G,Macdonald K,Spelman R,Davis S,Snell R

doi

10.1111/j.1365-2052.2012.02327.x

subject

Has Abstract

pub_date

2012-12-01 00:00:00

pages

781-4

issue

6

eissn

0268-9146

issn

1365-2052

journal_volume

43

pub_type

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