Abstract:
:The silkworm, Bombyx mori, is an economically important insect that was domesticated more than 5000 years ago. Its major economic traits focused on by breeders are quantitative traits, and an accurate and efficient QTL mapping method is necessary to explore their genetic architecture. However, current widely used QTL mapping models are not well suited for silkworm because they ignore female achiasmate and gender effects. In this study, we propose a composite method combining rational population selection and special mapping methods to map QTL in silkworm. By determining QTL for cocoon shell weight (CSW), we demonstrated the effectiveness of this method. In the CSW mapping process, only 56 markers were used and five loci or chromosomes were detected, more than in previous studies. Additionally, loci on chromosomes 1 and 11 dominated and accounted for 35.10% and 15.03% of the phenotypic variance respectively. Unlike previous studies, epistasis was detected between loci on chromosomes 11 and 22. These mapping results demonstrate the power and convenience of this method for QTL mapping in silkworm, and this method may inspire the development of similar approaches for other species with special genetic characteristics.
journal_name
Anim Genetjournal_title
Animal geneticsauthors
Li C,Zuo W,Tong X,Hu H,Qiao L,Song J,Xiong G,Gao R,Dai F,Lu Cdoi
10.1111/age.12311subject
Has Abstractpub_date
2015-08-01 00:00:00pages
426-32issue
4eissn
0268-9146issn
1365-2052journal_volume
46pub_type
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