APOB-associated cholesterol deficiency in Holstein cattle is not a simple recessive disease.

abstract：:The European sea bass (Dicentrarchus labrax L.) is a marine fish of key economic and cultural importance in Europe. It is now more an aquaculture than a fisheries species (>96% of the production in 2016), although modern rearing techniques date back only from the late 1980s. It also has high interest for evolutionary ...

journal_title：Animal genetics

authors： Vandeputte M,Gagnaire PA,Allal F

更新日期：2019-06-01 00:00:00

abstract：:The Siamese cat has a highly recognized coat colour phenotype that expresses pigment at the extremities of the body, such as the ears, tail and paws. This temperature-sensitive colouration causes a 'mask' on the face and the phenotype is commonly referred to as 'pointed'. Burmese is an allelic variant that is less tem...

journal_title：Animal genetics

authors： Lyons LA,Imes DL,Rah HC,Grahn RA

更新日期：2005-04-01 00:00:00

abstract：:The silkworm, Bombyx mori, is an economically important insect that was domesticated more than 5000 years ago. Its major economic traits focused on by breeders are quantitative traits, and an accurate and efficient QTL mapping method is necessary to explore their genetic architecture. However, current widely used QTL ...

journal_title：Animal genetics

authors： Li C,Zuo W,Tong X,Hu H,Qiao L,Song J,Xiong G,Gao R,Dai F,Lu C

更新日期：2015-08-01 00:00:00

abstract：:Performance data for 164,046 Thoroughbreds entered in a race or official barrier trial in Australia were provided by Racing Information Services Australia. Analyses estimating the heritability for a range of racing performance traits using a single-trait animal model were performed using ASREML-R. Log of cumulative ea...

journal_title：Animal genetics

authors： Velie BD,Hamilton NA,Wade CM

更新日期：2015-02-01 00:00:00

abstract：:Six distinct serotypes of the chicken B blood group system (which encodes the major histocompatibility complex) were identified in a commercial broiler breeder line (Line C). The B serotypes were compared by B-G restriction fragment length polymorphism (RFLP) analysis, allele-specific PCR typing test for B-LBII family...

journal_title：Animal genetics

authors： Livant EJ,Zheng D,Johnson LW,Shi W,Ewald SJ

更新日期：2001-06-01 00:00:00

abstract：:The inheritance pattern of the skeletal muscle hypertrophy phenotype caused by the callipyge gene has been characterized as polar overdominance. We hypothesized that this trait may be caused by a gain or loss of gene expression because of the reversible nature of the phenotype in paternal vs. maternal inheritance. Sup...

journal_title：Animal genetics

authors： Bidwell CA,Shay TL,Georges M,Beever JE,Berghmans S,Cockett NE

更新日期：2001-10-01 00:00:00

abstract：:In this study, we investigated at the genome-wide level if 20 years of artificial directional selection based on boar genetic evaluation obtained with a classical BLUP animal model shaped the genome of the Italian Large White pig breed. The most influential boars of this breed (n = 192), born from 1992 (the beginning ...

journal_title：Animal genetics

authors： Schiavo G,Galimberti G,Calò DG,Samorè AB,Bertolini F,Russo V,Gallo M,Buttazzoni L,Fontanesi L

更新日期：2016-04-01 00:00:00

abstract：:Recently, the Swiss breeding association reported an increasing number of white-spotted cattle in the Brown Swiss breed, which is normally solid brown coloured. A total of 60 Brown Swiss cattle with variably sized white abdominal spots, facial markings and depigmented claws were collected for this study. A genome-wide...

journal_title：Animal genetics

authors： Hofstetter S,Seefried F,Häfliger IM,Jagannathan V,Leeb T,Drögemüller C

更新日期：2019-02-01 00:00:00

abstract：:Israeli Holstein-Friesian dairy bulls were screened for restriction fragment length polymorphisms by hybridizing cloned DNA probes for bovine growth hormone, for chymosin, and for rat muscle beta-actin to restriction endonuclease-digested DNA immobilized on nitrocellulose filters. The population proved to be polymorph...

journal_title：Animal genetics

authors： Beckmann JS,Kashi Y,Hallerman EM,Nave A,Soller M

更新日期：1986-01-01 00:00:00

abstract：:The C3 polymorphism of equine serum or plasma revealed by agarose gel electrophoresis can be diagnosed with protein stain following acid protein fixation. In addition to the three alleles previously described (C31, C32, C33), a fourth allele (C34) was found. Population data for 25 domestic breeds and Equus przewalskii...

journal_title：Animal genetics

authors： Bowling AT,Dileanis S

更新日期：1990-01-01 00:00:00

abstract：:Two cDNA probes for the porcine calcium release channel gene (CRC) were used in restriction fragment length polymorphism (RFLP) analysis in an attempt to develop genetic markers linked to the malignant hyperthermia (stress susceptibility) gene (HAL). Three TaqI RFLPs, denoted CRC1-CRC3, each composed of two alleles, w...

journal_title：Animal genetics

authors： Mariani P,Johansson M,Ellegren H,Harbitz I,Juneja RK,Andersson L

更新日期：1992-01-01 00:00:00

abstract：:The 70 kilodalton heat shock proteins (Hsp70) are highly conserved molecular chaperones which have a crucial role in the stress response of the cell. In mammals, the Hsp70 proteins are encoded by a cluster of three genes: HSPA1A, HSPA1B and HSPA1L. In bovines, this cluster is located on chromosome 23 downstream of the...

journal_title：Animal genetics

authors： Suqueli García MF,Castellote MA,Feingold SE,Corva PM

更新日期：2017-08-01 00:00:00

abstract：:Genetic differences which exist in the prion protein gene (PRNP) have been reported to influence susceptibility of humans, sheep and goats to prion diseases. In cattle, however, none of the known coding polymorphisms has a direct effect on bovine spongiform encephalopathy (BSE). It has been reported that 23-bp inserti...

journal_title：Animal genetics

authors： Msalya G,Shimogiri T,Nishitani K,Okamoto S,Kawabe K,Minesawa M,Maeda Y

更新日期：2010-04-01 00:00:00

abstract：:A genetic disease observed in certain Quarter horses is hyperkalaemic periodic paralysis (HYPP). This disease causes attacks of paralysis which can be induced by ingestion of potassium. Recent studies have shown that HYPP in humans is due to single base changes within the adult skeletal muscle sodium channel gene. A l...

journal_title：Animal genetics

authors： Rudolph JA,Spier SJ,Byrns G,Hoffman EP

更新日期：1992-01-01 00:00:00

abstract：:After domestication 11 000 years ago in Asia Minor, the goat followed human migration to Europe and Asia. It was then introduced in Africa and is now raised all over the world. In this study, we exploited a dataset composed of 54 000 SNPs (Illumina goat DNA chip) to analyze the genetic diversity of 223 individuals bel...

journal_title：Animal genetics

authors： Oget C,Servin B,Palhière I

更新日期：2019-02-01 00:00:00

abstract：:Southern hybridization analysis of the ovine major histocompatibility complex (MHC) (MhcOvar) class II region, using sheep-specific probes for the DQA1, DQA2, DQB and DRA loci, has revealed extensive polymorphism. DQA1 and DQA2 had eight and 16 alleles respectively, DQB had six and DRA had three alleles. Little inform...

journal_title：Animal genetics

authors： Escayg AP,Hickford JG,Montgomery GW,Dodds KG,Bullock DW

更新日期：1996-10-01 00:00:00

abstract：:KIT mutations have been detected in different cancer subtypes, including melanoma. The gene also has been extensively studied in farm animals for its prominent role in coat color. The present work aimed at detecting KIT variants in a porcine model of cutaneous melanoma, the melanoblastoma-bearing Libechov Minipig (MeL...

journal_title：Animal genetics

authors： Fernández-Rodríguez A,Estellé J,Blin A,Muñoz M,Créchet F,Demenais F,Vincent-Naulleau S,Bourneuf E

更新日期：2014-06-01 00:00:00

abstract：:The KIT locus has been suggested to be a strong candidate region linked with whole-body roan in the F(2) population produced by intercrosses between Landrace and Korean Native pigs. In this manuscript, we report the finding of a novel alternative splicing event in the porcine KIT gene that results in the skipping of e...

journal_title：Animal genetics

authors： Lim HT,Zhong T,Cho IC,Seo BY,Kim JH,Lee SS,Ko MS,Park HB,Kim BW,Lee JH,Jeon JT

更新日期：2011-08-01 00:00:00

abstract：:The Chato Murciano (CM), a pig breed from the Murcia region in the southeastern region of Spain, is a good model for endangered livestock populations. The remaining populations are bred on approximately 15 small farms, and no herdbook exists. To assess the genetic threats to the integrity and survival of the CM breed,...

journal_title：Animal genetics

authors： Herrero-Medrano JM,Megens HJ,Crooijmans RP,Abellaneda JM,Ramis G

更新日期：2013-06-01 00:00:00

abstract：:A specific white spotting phenotype, termed finching or line-backed spotting, is known for all Pinzgauer cattle and occurs occasionally in Tux-Zillertaler cattle, two Austrian breeds. The so-called Pinzgauer spotting is inherited as an autosomal incompletely dominant trait. A genome-wide association study using 27 whi...

journal_title：Animal genetics

authors： Küttel L,Letko A,Häfliger IM,Signer-Hasler H,Joller S,Hirsbrunner G,Mészáros G,Sölkner J,Flury C,Leeb T,Drögemüller C

更新日期：2019-10-01 00:00:00

abstract：:Four new alleles at the rabbit (Oryctolagus cuniculus) mannose-6-phosphate isomerase (E.C. 5.3.1.8, MPI) locus are proposed to account for phenotypes observed after starch gel electrophoresis and enzymatic staining of red cell lysates and tissues. Population data from various wild and domestic rabbit populations are p...

journal_title：Animal genetics

authors： Vieira J,Ferrand N

更新日期：1995-02-01 00:00:00

abstract：:In this study, quantitative trait loci (QTL) for chemical and physical body composition, growth and feed intake in pigs were identified in a three-generation full-sib population, developed by crossing Pietrain sires with a commercial dam line. Phenotypic data from 315 F(2) animals were available for protein and lipid ...

journal_title：Animal genetics

authors： Duthie C,Simm G,Doeschl-Wilson A,Kalm E,Knap PW,Roehe R

更新日期：2008-04-01 00:00:00

abstract：:Atlantic salmon have been reared in the British Columbia, Canada aquaculture industry since the early 1980s. No breeding programmes spanned the entire production period and pedigree records were not kept for broodstocks prior to or since importation. Of the three recognized industry strains, two are of European ancest...

journal_title：Animal genetics

authors： Withler RE,Supernault KJ,Miller KM

更新日期：2005-02-01 00:00:00

abstract：:The Icelandic horse is a breed known mainly for its ability to perform the ambling four-beat gait 'tölt' and the lateral two-beat gait pace. The natural ability of the breed to perform these alternative gaits is highly desired by breeders. Therefore, the discovery that a nonsense mutation (C>A) in the DMRT3 gene was t...

journal_title：Animal genetics

authors： Jäderkvist Fegraeus K,Hirschberg I,Árnason T,Andersson L,Velie BD,Andersson LS,Lindgren G

更新日期：2017-12-01 00:00:00

abstract：:Fractures are medical conditions that compromise the athletic potential of horses and/or the safety of jockeys. Therefore, the reduction of fracture risk is an important horse and human welfare issue. The present study used molecular genetic approaches to determine the effect of genetic risk for fracture at four candi...

journal_title：Animal genetics

authors： Tozaki T,Kusano K,Ishikawa Y,Kushiro A,Nomura M,Kikuchi M,Kakoi H,Hirota K,Miyake T,Hill EW,Nagata S

更新日期：2020-02-01 00:00:00

abstract：:Recurrent airway obstruction (RAO) in horses is the result of an interaction of genetic and environmental factors and shares many characteristics with human asthma. Many studies have suggested that the interleukin-4 receptor gene (IL4R) is associated with this disease, and a QTL region on chromosome 13 containing IL4R...

journal_title：Animal genetics

authors： Klukowska-Rötzler J,Swinburne JE,Drögemüller C,Dolf G,Janda J,Leeb T,Gerber V

更新日期：2012-08-01 00:00:00

abstract：:Refinement of previous QTL on porcine chromosome 12 for fatty-acid composition and a candidate gene association analysis were conducted using an Iberian x Landrace cross. The concentrations of ten fatty acids were assayed in backfat tissue from which four metabolic ratios were calculated for 403 F2 animals. Linkage an...

journal_title：Animal genetics

authors： Muñoz G,Alves E,Fernández A,Ovilo C,Barragán C,Estellé J,Quintanilla R,Folch JM,Silió L,Rodríguez MC,Fernández AI

更新日期：2007-12-01 00:00:00

abstract：:Described is an alternative procedure for the phenotyping of pig alpha 1B-glycoprotein (PO2) and haemopexin. The procedure is based on the separation of serum samples by horizontal polyacrylamide gel electrophoresis, passive blotting onto a nitrocellulose (NC) sheet, and immunochemical detection using a mixture of a p...

journal_title：Animal genetics

authors： Kaláb P,Stratil A

更新日期：1989-01-01 00:00:00

abstract：:A candidate gene analysis of the microphthalmia-associated transcription factor (MITF) gene was used in an attempt to identify the genetic basis for a white-spotted coat color phenotype in the Asian swamp buffalo (Bubalus bubalis carabanensis). Ninety-three buffaloes-32 solid, 38 spotted and 23 white individuals-were ...

journal_title：Animal genetics

authors： Yusnizar Y,Wilbe M,Herlino AO,Sumantri C,Noor RR,Boediono A,Andersson L,Andersson G

更新日期：2015-12-01 00:00:00

abstract：:Cytochrome P450-aromatase enzyme (CYP19), which catalyses the conversion of androgens to oestrogens, is critical in ovarian differentiation and hence in the sex differentiation pathways of non-mammalian vertebrates. As in other fish species, distinct ovarian and brain aromatase genes have been identified in the Nile T...

journal_title：Animal genetics

authors： Harvey SC,Kwon JY,Penman DJ

更新日期：2003-02-01 00:00:00