Abstract:
:To increase the number of type I loci on the chicken linkage map, chicken genes containing microsatellite sequences (TAn, CAn, GAn, An) were selected from the nucleotide sequence database and primers were developed to amplify the repeats. Initially, 40 different microsatellites located within genes were tested on a panel of animals from diverse breeds, and identified 17 polymorphic microsatellites. These polymorphisms allowed us to add 15 new genes to the chicken linkage map. In addition, two genes were added to the chicken map by fluorescent in situ hybridization. As the map position of the human homologues of 13 of these genes is known, these markers extend the comparative map between chicken and man. Our results confirm and refine conserved regions between chicken and man on chicken chromosomes 2 and 7 and on linkage group E29C09W09. Furthermore, an additional conserved region is identified on chromosome 7.
journal_name
Anim Genetjournal_title
Animal geneticsauthors
Groenen MA,Crooijmans RP,Dijkhof RJ,Acar R,van der Poel JJdoi
10.1046/j.1365-2052.1999.00527.xsubject
Has Abstractpub_date
1999-12-01 00:00:00pages
418-22issue
6eissn
0268-9146issn
1365-2052journal_volume
30pub_type
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