abstract：:Anxiety is a complex psychological state which happens after stressful life experiences. Many factors such as daily life events, neurotransmitter systems, and different brain areas could influence anxiety behavior in humans and animals. For example, opioids and androgens decrease anxiety behavior both in humans and an...

journal_title：Acta neurobiologiae experimentalis

authors： Khakpay R,Khakpai F

更新日期：2020-01-01 00:00:00

abstract：:Persons with trisomy 21 (Down syndrome) present different phenotypes, including early neurodegeneration, which is prominent in the brain olfactory areas, and olfactory deficit. The use of in vivo techniques in animal models allows to characterize and follow up these slowly developing phenomena. We explored by means of...

journal_title：Acta neurobiologiae experimentalis

authors： Bontempi P,Cisterna B,Malatesta M,Nicolato E,Mucignat-Caretta C,Zancanaro C

更新日期：2020-01-01 00:00:00

abstract：:Poly (lactide‑co‑glycolide) (PLGA) nanoparticles (NPs) are biodegradable carriers that participate in the transport of neuroprotective drugs across the blood brain barrier (BBB). Targeted brain‑derived neurotrophic factor (BDNF) delivery across the BBB could provide neuroprotection in brain injury. We tested the neuro...

journal_title：Acta neurobiologiae experimentalis

authors： Kamarudin SN,Iezhitsa I,Tripathy M,Alyautdin R,Ismail NM

更新日期：2020-01-01 00:00:00

abstract：:Parkin and alpha-synuclein (α-syn) are two key proteins involved in the pathophysiology of Parkinson's disease (PD). Oligomerization/aggregation and excessive secretion of α-syn contributes to PD through free radical stress, mitochondrial impairment, and synaptic dysfunction. Parkin, an E3 ubiquitin ligase, is conside...

journal_title：Acta neurobiologiae experimentalis

authors： Jęśko H,Lenkiewicz AM,Wilkaniec A,Adamczyk A

更新日期：2019-01-01 00:00:00

abstract：:It is well known that the fetal ethanol exposure and prenatal stress may have adverse effects on brain development. Interestingly, some morphological and functional recovery from their teratogenic effects that take place during brain maturation. However, mechanisms that underlie this recovery are not fully elucidated....

journal_title：Acta neurobiologiae experimentalis

authors： Elibol B,Beker M,Sahbaz CD,Kilic U,Jakubowska-Doğru E

更新日期：2019-01-01 00:00:00

abstract：:For years, interneurons expressing vasoactive intestinal peptide (VIP) interneurons and their function within the neocortex have been shrouded in mystery. Their relatively small size and minimal representation in the cortex have made investigation difficult. Due to their service role performed in co‑operation with gli...

journal_title：Acta neurobiologiae experimentalis

authors： Posłuszny A

更新日期：2019-01-01 00:00:00

abstract：:Oxaliplatin is a third-generation, platinum-based antitumor drug used to treat colorectal cancer. Since its main adverse effect is neuropathic pain resulting from chemotherapy‑induced peripheral neuropathy (CIPN), this drug is used to study the neurobiology of CIPN in rodents and to search for analgesics that could at...

journal_title：Acta neurobiologiae experimentalis

authors： Furgała A,Sałat R,Sałat K

更新日期：2018-01-01 00:00:00

abstract：:Endocannabinoids (eCBs) are involved in the hippocampal mechanisms of spatial learning and memory in rats. Although eCBs exert many of their actions on spatial learning and memory via CB1 receptors, the putative cannabinoid receptor GPR55 (expressed in the hippocampus, cortex, forebrain, cerebellum and striatum) seems...

journal_title：Acta neurobiologiae experimentalis

authors： Marichal-Cancino BA,Fajardo-Valdez A,Ruiz-Contreras AE,Méndez-Díaz M,Prospéro-García O

更新日期：2018-01-01 00:00:00

abstract：:The purpose of this review is to summarize current knowledge about the gut microbiota in neuropsychiatric disorders. It is estimated that the human gut is colonized by up to 1018 microorganisms, mostly anaerobic bacteria. The gut microbiome is responsible for multiple functions, e.g. tightness of the intestine barrier...

journal_title：Acta neurobiologiae experimentalis

authors： Grochowska M,Wojnar M,Radkowski M

更新日期：2018-01-01 00:00:00

abstract：:Mutations in the PINK1 gene are responsible for typical symptoms of Parkinson's disease. Using Drosophila melanogaster mutant PINK1B9 and after PINK1 silencing with RNAi using transgenic lines, we observed defects in synapses and behavior. The lack or reduced expression of PINK1 prolonged sleep during the day (nap) an...

journal_title：Acta neurobiologiae experimentalis

authors： Doktór B,Damulewicz M,Krzeptowski W,Bednarczyk B,Pyza EM

更新日期：2018-01-01 00:00:00

abstract：:In the filled-space (or Oppel-Kundt) illusion, the filled part of the stimulus for most observers appears longer in comparison with the empty one. In the first two experimental series of the present study, we investigated the illusory effect as a function of continuous filling (by a shaft-line segment) of the referenc...

journal_title：Acta neurobiologiae experimentalis

authors： Bulatov A,Bulatova N,Surkys T,Mickienė L

更新日期：2017-01-01 00:00:00

abstract：:Stroke is the second leading cause of death worldwide, affecting about 240 people a day in South Africa and leaving survivors with residual disabilities. At the moment, there is no clinically approved neuroprotective product for stroke but the consumption of plant polyphenols has been suggested to offer some protectio...

journal_title：Acta neurobiologiae experimentalis

authors： Akinrinmade O,Omoruyi S,Dietrich D,Ekpo O

更新日期：2017-01-01 00:00:00

abstract：:Deprivation of patterned visual information, as in early onset congenital cataract patients, results in a severe impairment in global motion perception. Previously we reported a delayed maturation of the peripheral visual field representation in primary visual area 17, based on a 2-D DIGE screen for protein expression...

journal_title：Acta neurobiologiae experimentalis

authors： Laskowska-Macios K,Arckens L,Kossut M,Burnat K

更新日期：2017-01-01 00:00:00

abstract：:Functional interactions between serotoninergic and GABAergic systems in the vertebrate retina are largely unknown. In this study, the effects of isolated or combined stimulation of the serotonin receptors (with 100 μM serotonin) and ionotropic GABAA and GABAC receptors (with 5 mM TACA) on the electroretinographic (ERG...

journal_title：Acta neurobiologiae experimentalis

authors： Popova E,Kupenova P

更新日期：2017-01-01 00:00:00

abstract：:Huntington's disease is an autosomal dominant progressive neurodegenerative disease, which results in a decreased quality of life and an early death. A high prevalence of vitamin D deficiency was first described in a 2013 study in patients with manifest Huntington's disease, where serum vitamin D level was found to be...

journal_title：Acta neurobiologiae experimentalis

authors： Molnár MF,Török R,Szalárdy L,Sümegi E,Vécsei L,Klivényi P

更新日期：2016-01-01 00:00:00

abstract：:Anxiety disorders are a social problem due to their prevalence and consequences. It is crucial to explore the influence of anxiety on cognitive processes. In this study we recorded EEG activity from 73 subjects (35 patients, 38 controls, matched for age and education) during performance of the Continuous Attention Tas...

journal_title：Acta neurobiologiae experimentalis

authors： Gmaj B,Januszko P,Kamiński J,Drozdowicz E,Kopera M,Wołyńczyk-Gmaj D,Szelenberger W,Wojnar M

更新日期：2016-01-01 00:00:00

abstract：:Adult mammalian brain contains a number of specialized neurovascular structures termed "niches" that act as sources of neuronal cells throughout the individual's life. Some of the niches generate neurons to satisfy the need for 'replacement' neurons within the same or closely located brain structures, whereas the othe...

journal_title：Acta neurobiologiae experimentalis

authors： Sulejczak D,Chrapusta SJ,Kozłowski W,Frontczak-Baniewicz M

更新日期：2016-01-01 00:00:00

abstract：:This study aimed to provide a simple way to approach group differences by independent component analysis when researching functional connectivity changes of resting-state network in brain disorders. We used baseline resting state functional magnetic resonance imaging from the Alzheimer's disease neuroimaging initiativ...

journal_title：Acta neurobiologiae experimentalis

authors： Chun-Chao H,Shang-Hua L,Ching-Po L,Disease Neuroimaging Initiative TA

更新日期：2016-01-01 00:00:00

abstract：:The present paper studies the perceived orientation of line patterns with variable elongation, line length, orientation jitter, and presentation time. It evaluates whether the internal noise and sampling efficiency evaluated by equivalent noise paradigm (Pelli 1981) depend on the spatial configuration and temporal cha...

journal_title：Acta neurobiologiae experimentalis

authors： Bocheva N,Stefanov S,Stefanova M,Genova B

更新日期：2015-01-01 00:00:00

abstract：:The intergeniculate leaflet (IGL) of the thalamus constitutes a small but important part of the neural network controlling circadian activity in rodents. It appears that IGL integrates photic cues from retina with non-photic information originating from different nonspecific brain systems. Subsequently, this integrate...

journal_title：Acta neurobiologiae experimentalis

authors： Palus K,Chrobok Ł,Lewandowski MH

更新日期：2015-01-01 00:00:00

abstract：:Due to technological advances in electrophysiology, there is renewed interest in the analysis of local field potentials recorded at many sites simultaneously. In this paper the main problems related to the analysis of LFP are presented, and recent developments in the data analysis methods are reviewed. The focus of th...

journal_title：Acta neurobiologiae experimentalis

authors： Łęski S

更新日期：2015-01-01 00:00:00

abstract：:The parabrachial complex has been related to various rewarding or aversive behavioral processes, including taste aversion learning and conditioned place aversion. This study examined the effect of tiapride, an antagonist of D2/D3 dopaminergic receptors, on place aversion induced by electrical stimulation of the extern...

journal_title：Acta neurobiologiae experimentalis

authors： Hurtado MM,García R,Puerto A

更新日期：2014-01-01 00:00:00

abstract：:It is well-known that the cholinergic system and the muscarinic cholinergic receptors are associated with cognitive functions. Here we examined whether a non-selective muscarinic receptor antagonist scopolamine affects learning performance and/or synaptic plasticity during the memory consolidation period. Adult male W...

journal_title：Acta neurobiologiae experimentalis

authors： Dobryakova YV,Gurskaya O,Markevich VA

更新日期：2014-01-01 00:00:00

abstract：:Hypothyroidism affects neuron population dynamics in the hippocampus of the adult rat, with neuronal damage as the main feature of its effect. This effect is prevented by the blockade of NMDA receptors, which suggests that glutamatergic activity mediates cell death in this condition. Glutamate can also stimulate cell ...

journal_title：Acta neurobiologiae experimentalis

authors： Alva-Sanchez C,Rodriguez A,Villanueva I,Anguiano B,Aceves C,Pacheco-Rosado J

更新日期：2014-01-01 00:00:00

abstract：:Response generalization to a novel stimulus occurs when the new stimulus shares common features with the stimulus used in the original learning. Given the many recent studies suggesting that the perirhinal cortex is critical for disambiguating stimuli that share representational/perceptual elements, we hypothesize tha...

journal_title：Acta neurobiologiae experimentalis

authors： Ramos JM

更新日期：2014-01-01 00:00:00

abstract：:Preconditioning is an experimental strategy for reducing ischemic brain damage. There are reports that brief exposure of neurons to NMDA-receptor antagonists may be an adequate preconditioning stressor. We studied effects of preconditioning of the cerebellar granule cells (CGC) in primary culture by 30-minute exposure...

journal_title：Acta neurobiologiae experimentalis

authors： Słomka M,Kuszczyk M,Łazarewicz JW,Makarewicz D

更新日期：2014-01-01 00:00:00

abstract：:Leukemia inhibitory factor (LIF) is a neuroprotective cytokine that is necessary for the normal development of astrocytes. Oxygen-glucose deprivation (OGD) can induce astrocyte proliferation by increasing hypoxia-inducible factor alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF). Here, we studied whethe...

journal_title：Acta neurobiologiae experimentalis

authors： Fan YY,Zhang JM,Wang H,Liu XY,Yang FH

更新日期：2013-01-01 00:00:00

abstract：:A modified method of injection into the cerebellomedullary (CM) cistern of mice was developed based on fixation of the mouse with a special mask under inhalation anesthesia, and exposure of the sagittal suture of the cranium and midline of the nape to allow us to visualize injection point directly. The accuracy of the...

journal_title：Acta neurobiologiae experimentalis

authors： Chen Y,Imai H,Ito A,Saito N

更新日期：2013-01-01 00:00:00

abstract：:In the present communication, a possible role of perceptual displacements of stimulus elements in the occurrence of visual illusions of extent has been considered. In psychophysical experiments with a single set of Müller-Lyer wings, subjects were asked to place an imaginary reference rectangle into a position that ma...

journal_title：Acta neurobiologiae experimentalis

authors： Bulatov A,Mickienė L,Bulatova N,Bielevičius A

更新日期：2013-01-01 00:00:00

abstract：:In the context of cell therapy, the epigenetic status of core stemness transcription factor (STF) genes regulating the cell proliferation/differentiation program is of primary interest. Our results confirmed that in vitro differentiation of the umbilicalcord-blood-derived-neural-stem-cells (HUCB-NSC) coincides with th...

journal_title：Acta neurobiologiae experimentalis

authors： Habich A,Szablowska-Gadomska I,Zayat V,Buzanska L,Domańska-Janik K

更新日期：2013-01-01 00:00:00

abstract：:Stem cell therapy is a promising strategy for overcoming the limitations of current treatment methods. The modification of stem cell properties may be necessary to fully exploit their potential. Genetic engineering, with an abundance of methodology to induce gene expression in a precise and well-controllable manner, i...

journal_title：Acta neurobiologiae experimentalis

authors： Nowakowski A,Andrzejewska A,Janowski M,Walczak P,Lukomska B

更新日期：2013-01-01 00:00:00

abstract：:Autism, Asperger's syndrome (AS), and pervasive developmental disorder - not otherwise specified (PDD-NOS) compose the overall diagnostic category of autism spectrum disorder (ASD). Subjects diagnosed with an ASD have a male:female ratio of 4:1, and among subjects diagnosed with AS the male:female ratio is as high as ...

journal_title：Acta neurobiologiae experimentalis

authors： Geier DA,Kern JK,King PG,Sykes LK,Geier MR

更新日期：2012-01-01 00:00:00

abstract：:In this study we evaluated biochemical blood serum parameters and the association of Cyclin-dependent kinase 5 (CDK5) gene polymorphisms with the risk of Alzheimer's disease (AD) in the Polish population. We observed an elevated total cholesterol, low-density lipoproteins (LDL) and homocysteine levels and lower concen...

journal_title：Acta neurobiologiae experimentalis

authors： Czapski GA,Maruszak A,Styczyńska M,Żekanowski C,Safranow K,Strosznajder JB

更新日期：2012-01-01 00:00:00

abstract：:Disturbances of enteric nerve-mediated anorectal evacuation mechanisms have medical and social impact. The study aimed at further eliciting the contribution of cholinergic and nitrergic neurotransmission systems to modular nerve networks in different regions of Wistar rat anorectum. Electrical field stimulation (EFS, ...

journal_title：Acta neurobiologiae experimentalis

authors： Stavreva G,Radomirov R

更新日期：2012-01-01 00:00:00

abstract：:Thyroid hormones are essential for normal brain development and very important in the normal functioning of the brain. Thyroid hormones action in the adult brain has not been widely studied. The effects of adult hyperthyroidism are not as well understood as adult hypothyroidism, mainly in hippocampal granular cells. T...

journal_title：Acta neurobiologiae experimentalis

authors： Martí-Carbonell MA,Garau A,Sala-Roca J,Balada F

更新日期：2012-01-01 00:00:00

abstract：:The objective was to assess changes in the width of the subarachnoid space (SAS) and amplitude of cerebrovascular pulsation (CVP) during acute elevation of intracranial pressure (ICP) using Near Infrared Transillumination/Back Scattering Sounding (NIR-T/BSS). Changes in the width of the SAS and amplitude of CVP were o...

journal_title：Acta neurobiologiae experimentalis

authors： Frydrychowski AF,Wszedybyl-Winklewska M,Guminski W,Przyborska A,Kaczmarek J,Winklewski PJ

更新日期：2011-01-01 00:00:00

abstract：:Inherited or acquired oligodendrocyte deficiency or abnormalities usually lead to severe neurological disorders, common in humans and animals. The wide spectrum of diseases to be treated, their frequency and lack of effective treatments result in an urgent need to elaborate alternative options such as cell replacement...

journal_title：Acta neurobiologiae experimentalis

authors： Sypecka J

更新日期：2011-01-01 00:00:00

abstract：:Parkinson's disease (PD) is a common neurodegenerative disease that appears essentially as a sporadic condition. PD is well known to be a chronic and progressive neurodegenerative disease produced by a selective degeneration of dopaminergic neurons in the substantia nigra pars compacta. The main clinical features of P...

journal_title：Acta neurobiologiae experimentalis

authors： Yokoyama H,Kuroiwa H,Kasahara J,Araki T

更新日期：2011-01-01 00:00:00

abstract：:Tight junction, one of the type of cell-cell junctions, controls the paracellular permeability across the lateral intercellular space and maintains the cell polarity. Tight junctions consist of transmembrane proteins: members of tight junction-associated MARVEL protein (TAMP) family, claudins and junctional adhesion m...

journal_title：Acta neurobiologiae experimentalis

authors： Bednarczyk J,Lukasiuk K

更新日期：2011-01-01 00:00:00

abstract：:Clinical and immunopathological evidence support a potential role of inflammatory cytokines in Alzheimer's disease (AD). However, studies examining the association between cytokine gene polymorphisms and risk of developing AD yielded conflicting results. The objective of our study was to evaluate the association betwe...

journal_title：Acta neurobiologiae experimentalis

authors： Shawkatová I,Javor J,Párnická Z,Vrazda L,Novák M,Buc M

更新日期：2010-01-01 00:00:00