Abstract:
:The intergeniculate leaflet (IGL) of the thalamus constitutes a small but important part of the neural network controlling circadian activity in rodents. It appears that IGL integrates photic cues from retina with non-photic information originating from different nonspecific brain systems. Subsequently, this integrated signal is passed to the master biological clock - the suprachiasmatic nuclei (SCN). The common neurotransmitter of biological clock neural structures, the gamma-amino-butyric acid (GABA) is expressed in many, if not all, IGL and SCN neurons. Whole-cell patch clamp in vitro electrophysiological experiments were performed in order to evaluate GABA's influence on single IGL neurons in rat. Most neurons were hyperpolarized by GABA application and this effect was caused by activation of GABAA as well as GABAB receptors. The presence of GABAB receptors in rat's IGL has been suggested for the first time.
journal_name
Acta Neurobiol Exp (Wars)journal_title
Acta neurobiologiae experimentalisauthors
Palus K,Chrobok Ł,Lewandowski MHsubject
Has Abstractpub_date
2015-01-01 00:00:00pages
27-35issue
1eissn
0065-1400issn
1689-0035pii
7502journal_volume
75pub_type
杂志文章abstract::The parabrachial complex has been related to various rewarding or aversive behavioral processes, including taste aversion learning and conditioned place aversion. This study examined the effect of tiapride, an antagonist of D2/D3 dopaminergic receptors, on place aversion induced by electrical stimulation of the extern...
journal_title:Acta neurobiologiae experimentalis
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journal_title:Acta neurobiologiae experimentalis
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doi:
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doi:
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pub_type: 杂志文章
doi:
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
doi:
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doi:
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doi:
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pub_type: 杂志文章,评审
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