abstract：:In this study, we performed an integrated physiological and chloroplast proteome analysis of wheat seedling leaves under salt and osmotic stresses by label-free based quantitative proteomic approach. Both salt and osmotic stresses significantly increased the levels of abscisic acid and methyl jasmonate and led to dama...

journal_title：Journal of proteomics

authors： Zhu D,Luo F,Zou R,Liu J,Yan Y

更新日期：2021-03-15 00:00:00

abstract：:The pollen beetle is a major pest of oilseed rape. Although various resistance mechanisms have been identified, such as kdr (mutation in the sodium channel) and metabolic resistance (CYP overexpression), other "hidden" factors also exist. Some studies have stressed the importance of epistasis as a genetic background. ...

journal_title：Journal of proteomics

authors： Kocourek F,Stara J,Sopko B,Talacko P,Harant K,Hovorka T,Erban T

更新日期：2021-02-20 00:00:00

abstract：:Gel electrophoresis-based and shotgun approaches are the most employed proteomic platforms in plant biology research, with the latter replacing the former in the last years. We have compared 2-DE-MALDI-TOF/TOF and GeLC-Orbitrap/MS analyses using the same protein extracts from Quercus ilex cotyledons at different devel...

journal_title：Journal of proteomics

authors： Sghaier-Hammami B,Castillejo MÁ,Baazaoui N,Jorrín-Novo JV,Escandón M

更新日期：2021-02-20 00:00:00

abstract：:The role of Leishmania braziliensis in the development of different clinical forms of American Tegumentary Leishmaniasis (ATL) is unclear, but it has been suggested that molecules secreted/released by parasites could modulate the clinical outcome. Here, we analyzed the infection rate and cytokine profile of macrophage...

journal_title：Journal of proteomics

authors： Rodríguez-Vega A,Losada-Barragán M,Berbert LR,Mesquita-Rodrigues C,Bombaça ACS,Menna-Barreto R,Aquino P,Carvalho PC,Padrón G,de Jesus JB,Cuervo P

更新日期：2021-02-10 00:00:00

abstract：:Spectral similarity calculation is widely used in protein identification tools and mass spectra clustering algorithms while comparing theoretical or experimental spectra. The performance of the spectral similarity calculation plays an important role in these tools and algorithms especially in the analysis of large-sca...

journal_title：Journal of proteomics

authors： Qin C,Luo X,Deng C,Shu K,Zhu W,Griss J,Hermjakob H,Bai M,Perez-Riverol Y

更新日期：2021-02-10 00:00:00

abstract：:Follicular atresia is initiated with the apoptosis of granulosa cells (GCs) after birth in mammals. The molecular mechanisms underlying GC apoptosis during follicular selection are unclear at present. The objective of this study is to identify the proteins and pathways that may be involved in porcine follicular atresi...

journal_title：Journal of proteomics

authors： Shan X,Yu T,Yan X,Wu J,Fan Y,Guan X,Fang F,Lin Y,Zhang Y,Li Y,Liu Y

更新日期：2021-02-10 00:00:00

abstract：:The α,β-unsaturated aldehyde 4-hydroxynonenal (HNE) is formed through lipid peroxidation during oxidative stress. As a highly reactive electrophile, it is able to form adducts with various biomolecules, including proteins. These protein modifications could modulate many signaling pathways, as well as cell differentiat...

journal_title：Journal of proteomics

authors： Geib T,Iacob C,Jribi R,Fernandes J,Benderdour M,Sleno L

更新日期：2021-02-10 00:00:00

abstract：:Flooding constrains soybean growth, while melatonin enhances the ability of plants to tolerate abiotic stresses. To interpret the melatonin-mediated flooding response in soybeans, proteomic analysis was performed in root tips. Retarded growth and severe cell death were observed in flooded soybeans, but these phenotype...

journal_title：Journal of proteomics

authors： Wang X,Li F,Chen Z,Yang B,Komatsu S,Zhou S

更新日期：2021-02-10 00:00:00

abstract：:Drug resistance and relapse after treatment of visceral leishmaniasis (VL) with the chemotherapeutic drugs has impeded the VL elimination programme especially, in the endemic region of Bihar, India. Currently, Antimonials (Sbv) have been rendered obsolete (Bihar) as frequent treatment failure and relapse in Sbv treate...

journal_title：Journal of proteomics

authors： Routaray CB,Bhor R,Bai S,Kadam NS,Jagtap S,Doshi PJ,Sundar S,Sawant S,Kulkarni MJ,Pai K

更新日期：2021-02-10 00:00:00

abstract：:Salinity can induce Mesembryanthemum crystallinum to shift its photosynthesis from C3 to crassulacean acid metabolism (CAM), leading to enhanced plant water use efficiency. Studying how M. crystallinum changes its carbon fixation pathways is important for potential translation into crops and enhancing crop resilience....

journal_title：Journal of proteomics

authors： Guan Q,Kong W,Zhu D,Zhu W,Dufresne C,Tian J,Chen S

更新日期：2021-01-16 00:00:00

abstract：:Late diagnosis of pancreatic ductal adenocarcinoma (PDA) is one of the reasons of its low 5-year survival rate and it is due to its unspecific symptoms during the first stages of the disease and the lack of reliable serological markers. Since PDA shows an altered glycan expression, here we have focused on finding nove...

journal_title：Journal of proteomics

authors： Guerrero PE,Duran A,Ortiz MR,Castro E,Garcia-Velasco A,Llop E,Peracaula R

更新日期：2021-01-16 00:00:00

abstract：:Fructus Rosae Roxburghii (FRR) has been considered as edible and medicinal fruit possessing antiatherosclerotic effect, but the mechanism is still unclear. HLP is material basis for AS formation. Under FRR action, TC, TG, LDL, HDL and ASI in serum were regulated to control level. Differentially expressed proteins in l...

journal_title：Journal of proteomics

authors： Song P,Shen X

更新日期：2021-01-06 00:00:00

abstract：:Fatty acid desaturate 2 (Fads2) is associated with many chronic diseases. Nevertheless, comprehensive researches on its role have not been performed. We here conducted an integrated analysis of long-chain polyunsaturated fatty acid (LC-PUFA) metabolism of fads2-deletion zebrafish (fads2-/-) by transcriptomics, proteom...

journal_title：Journal of proteomics

authors： Zhao Y,Yang G,Wu N,Cao X,Gao J

更新日期：2020-10-30 00:00:00

abstract：:The application of silkworm hybrids have promoted the innovation and development of agricultural technology, but the mechanism of heterosis in silkworm has not been explained clearly. In this study, the heterosis of silkworm in the aspects of body weight, silk gland and cocoon weight was investigated by means of silkw...

journal_title：Journal of proteomics

authors： Xiao R,Yuan Y,Zhu F,He S,Ge Q,Wang X,Taha R,Chen K

更新日期：2020-10-30 00:00:00

abstract：:Ubiquitylation is an elaborate post-translational modification involved in all biological processes. Its pleotropic effect is driven by the ability to form complex polyubiquitin chain architectures that can influence biological functions. In this study, we optimised sample preparation and chromatographic separation of...

journal_title：Journal of proteomics

authors： Heunis T,Lamoliatte F,Marín-Rubio JL,Dannoura A,Trost M

更新日期：2020-10-30 00:00:00

abstract：:Tissues hypoxia caused by hemorrhage is a common complication in many clinical diseases. However, its pathological mechanism remains largely unknown. To partly address this issue, an ischemic-hypoxic rat model was established and the plasma proteomic and metabolic profiles were quantified and analyzed using TMT-based ...

journal_title：Journal of proteomics

authors： He R,Kong Y,Fang P,Li L,Shi H,Liu Z

更新日期：2020-09-30 00:00:00

abstract：:Serum amyloid A (SAA) is a well-described acute phase protein induced during the acute phase response (APR) to infection. Four isoform specific genes are found in most mammals. Depending on species, SAA3 and SAA4 are generally preferentially expressed extrahepatically whereas SAA1 and SAA2 are hepatic isoforms dominat...

journal_title：Journal of proteomics

authors： Leuchsenring AB,Karlsson C,Bundgaard L,Malmström J,Heegaard PMH

更新日期：2020-09-15 00:00:00

abstract：:Reproductive stage is very sensitive to various forms of environmental stresses such as drought stress. The proteomic analysis of anther during pollen development in response to drought stress was performed using a label-free quantitative shotgun proteomic technique to define the underlying molecular principles in two...

journal_title：Journal of proteomics

authors： Mehri N,Fotovat R,Mirzaei M,Fard EM,Parsamatin P,Hasan MT,Wu Y,Ghaffari MR,Salekdeh GH

更新日期：2020-08-30 00:00:00

abstract：:The Duvernoy's gland secretory proteome of the false coral snake Rhinobothryum bovallii (Costa Rica), unveiled applying bottom-up venomics, comprises a handful of toxins belonging to only three protein families, three-finger toxin (3FTx), cysteine-rich secretory protein (CRISP), and snake venom metalloprotease (PIII-S...

journal_title：Journal of proteomics

authors： Calvete JJ,Bonilla F,Granados-Martínez S,Sanz L,Lomonte B,Sasa M

更新日期：2020-08-15 00:00:00

abstract：:Neurotransmitter:sodium symporters (NSS) are integral membrane proteins (IMP), responsible for reuptake of neurotransmitters from the synaptic cleft. Due to challenges in production of mammalian NSS in their active form, the prokaryotic hydrophobic amino acid transporter, LeuT, served here as a steadfast model for elu...

journal_title：Journal of proteomics

authors： Möller IR,Merkle PS,Calugareanu D,Comamala G,Schmidt SG,Loland CJ,Rand KD

更新日期：2020-08-15 00:00:00

abstract：:Posttranslational modification by ubiquitination targets proteins for degradation, recycling, stabilization or altered trafficking, and as such can alter cellular signaling pathways. The substrate specificity of this multistep process is controlled by ubiquitin ligases, including those of the HECT domain-containing NE...

journal_title：Journal of proteomics

authors： Manning J,Windley SP,Sandow JJ,Shah SS,Western P,Wilhelm D,Kumar S

更新日期：2020-07-15 00:00:00

abstract：:Radiation-induced colorectal fibrosis (RICF) after pelvic radiotherapy can lead to stenosis and affect patients' quality of life. However, to date, few effective prevention and treatment methods for RICF have been implemented in clinical practice. Therefore, there is a strong need to investigate the molecular events u...

journal_title：Journal of proteomics

authors： Huang S,Wang X,Sun Y,Lu X,Jiang W,Chen Z,Huang Y,Chi P

更新日期：2020-07-15 00:00:00

abstract：:The biological functions of protein glycosylation have been increasingly recognized but not yet been very well understood, especially in lower organisms. Silkworm as a model lepidopteran insect and important economic insect, has been widely studied in life science, however, the current knowledge on the glycosylation s...

journal_title：Journal of proteomics

authors： Zhu F,Li D,Song D,Huo S,Ma S,Lü P,Liu X,Yao Q,Chen K

更新日期：2020-06-30 00:00:00

abstract：:The oral mucosal pellicle is a thin lubricating layer generated by the binding of saliva proteins on epithelial oral cells. The protein composition of this biological structure has been to date studied by targeted analyses of specific salivary proteins. In order to perform a more exhaustive proteome characterization o...

journal_title：Journal of proteomics

authors： Cabiddu G,Maes P,Hyvrier F,Olianas A,Manconi B,Brignot H,Canon F,Cabras T,Morzel M

更新日期：2020-06-30 00:00:00

abstract：:Phytophthora sojae is a widely distributed, destructive oomycete plant pathogen that has been developed as a model for oomycete biology. Given the important but limited reports on the comparison of the sexual and asexual stages in Phytophthora, we performed a large-scale quantitative proteomics study on two key asexua...

journal_title：Journal of proteomics

authors： Zhang C,Cui T,Zhang F,Xue Z,Miao J,Wang W,Liu X

更新日期：2020-06-15 00:00:00

abstract：:The recognition by specific T helper cells of viral antigenic peptides complexed with HLA class II molecules exposed on the surface of antigen presenting cells is the first step of the complex cascade of immunological events that generates the protective cellular and humoral immune responses. The HLA class II-restrict...

journal_title：Journal of proteomics

authors： Lorente E,Barnea E,Mir C,Admon A,López D

更新日期：2020-06-15 00:00:00

abstract：:Protein methylation is one of the common post-translational modifications involved in diverse biological processes including signal transduction, transcriptional regulation, DNA repairing, gene activation, gene repression, and RNA processing. Due to technique limitation, the investigation of protein methylation in can...

journal_title：Journal of proteomics

authors： Liu Z,Wang Q,Mao J,Wang K,Fang Z,Miao QR,Ye M

更新日期：2020-05-15 00:00:00

abstract：:Deciphering Plasmodium vivax biology has long been a challenge for groups working on this parasite, mainly due to the complications involved in propagating it in vitro. However, adapting P. vivax strains in non-human primates and the arrival of high-performance analysis methods has led to increased knowledge regarding...

journal_title：Journal of proteomics

authors： Moreno-Pérez DA,Patarroyo MA

更新日期：2020-04-30 00:00:00

abstract：:Renal cell carcinoma (RCC) is one of the most lethal type of tumors and is twice more frequent in men than in women. Initial symptoms are unspecific and belated thus increasing mortality. Moreover, current diagnostic and monitoring tools are harmful for the patient and unspecific in low-grade tumors. Therefore, novel ...

journal_title：Journal of proteomics

authors： Oto J,Fernández-Pardo Á,Roca M,Plana E,Solmoirago MJ,Sánchez-González JV,Vera-Donoso CD,Martínez-Sarmiento M,España F,Navarro S,Medina P

更新日期：2020-04-30 00:00:00

abstract：:We investigated the skin sensitization hazard of glyphosate, the surfactant polyethylated tallow amine (POEA) and two commercial glyphosate-containing formulations using different omics-technologies based on a human dendritic cell (DC)-like cell line. First, the GARD™skin assay, investigating changes in the expression...

journal_title：Journal of proteomics

authors： Lindberg T,de Ávila RI,Zeller KS,Levander F,Eriksson D,Chawade A,Lindstedt M

更新日期：2020-04-15 00:00:00

abstract：:The molecular mechanisms whereby placental growth factor (PlGF) mediates its effects in nonproliferative diabetic retinopathy (DR) are unknown. To better understand the role of PlGF in DR, we used tandem mass tags (TMT)-labeled quantitative proteomics to human retinal endothelial cells (HRECs), treated anti-PlGF antib...

journal_title：Journal of proteomics

authors： Saddala MS,Lennikov A,Huang H

更新日期：2020-04-15 00:00:00

abstract：:In pre-weaning calves, both leucine and threonine play important roles in growth and muscle metabolism. In this study, metabolomics, proteomics and clinical chemistry were used to assess the effects of leucine and threonine supplementation added to milk replacer on 14 newborn Holstein male calves: 7 were fed a control...

journal_title：Journal of proteomics

authors： Yu K,Matzapetakis M,Horvatić A,Terré M,Bach A,Kuleš J,Yeste N,Gómez N,Arroyo L,Rodríguez-Tomàs E,Peña R,Guillemin N,de Almeida AM,Eckersall PD,Bassols A

更新日期：2020-03-30 00:00:00

abstract：:Selenoprotein F (Selenof) is an endoplasmic reticulum (ER)-resident protein. It may be functionally linked to glycoprotein folding in the ER but the detail function is not fully understood. To study the function of Selenof, we used CRISPR/Cas9 to generate Selenof knockout mice and performed proteomic analysis of hepat...

journal_title：Journal of proteomics

authors： Zheng X,Ren B,Wang H,Huang R,Zhou J,Liu H,Tian J,Huang K

更新日期：2020-03-20 00:00:00

abstract：:The aim of the present study was to evaluate the differences in salivary proteome at rest and in response to an acute exercise in men and women. For this, unstimulated whole saliva samples in rest and after a bout resistance exercise leading to failure (ELF) of both men and women (n = 5 for each sex) were subjected to...

journal_title：Journal of proteomics

authors： Franco-Martínez L,González-Hernández JM,Horvatić A,Guillemin N,Cerón JJ,Martínez-Subiela S,Sentandreu MÁ,Brkljačić M,Mrljak V,Tvarijonaviciute A,Jiménez Reyes P

更新日期：2020-03-01 00:00:00

abstract：:Termite soldiers constitute the defensive frontline of the colonies, despite workers also perform such tasks, especially within the Neotropical Apicotermitinae, in which all species are soldierless. Workers of the genus Ruptitermes display an extreme form of defense, characterized by body rupture and release of a stic...

journal_title：Journal of proteomics

authors： Costa-Leonardo AM,da Silva IB,Poiani SB,Dos Santos-Pinto JRA,Esteves FG,da Silva LHB,Palma MS

更新日期：2020-02-20 00:00:00

abstract：:Protein methylation has been proposed as an important post-translational modification, which occurs predominantly on lysine and arginine residues. Recent discoveries have revealed that protein methylation is also present on non-histones besides histones, and plays critical roles in regulating protein stability and fun...

journal_title：Journal of proteomics

authors： Liang Q,Geng Q,Jiang L,Liang M,Li L,Zhang C,Wang W

更新日期：2020-02-20 00:00:00

abstract：:Lactobacillus fermentum is a natural resident of the human GIT and is used as a probiotic. A unique property of L. fermentum is its ability to tolerate, colonize, and survive in the harsh conditions of bile, which facilitates transient colonization of the host colon. In the current study, we investigated the key mecha...

journal_title：Journal of proteomics

authors： Ali SA,Singh P,Tomar SK,Mohanty AK,Behare P

更新日期：2020-02-20 00:00:00

abstract：:The obligate intracellular bacterial pathogen, Chlamydia trachomatis, develops within a membrane-bound vacuole termed the inclusion. Affinity purification-mass spectrometry (AP-MS) experiments to study the interactions that occur at the chlamydial inclusion membrane have been performed and, more recently, combined wit...

journal_title：Journal of proteomics

authors： Olson MG,Ouellette SP,Rucks EA

更新日期：2020-02-10 00:00:00

abstract：:Porcine circovirus type 3 (PCV3) infection induces porcine dermatitis and nephropathy syndrome, reproductive failure, and multisystemic inflammatory lesions in piglets and sows. To better understand the host responses to PCV3 infection, isobaric tags for relative and absolute quantification (iTRAQ) labeling combined w...

journal_title：Journal of proteomics

authors： Jiang H,Wei L,Wang D,Wang J,Zhu S,She R,Liu T,Tian J,Quan R,Hou L,Li Z,Chu J,Zhou J,Guo Y,Xi Y,Song H,Yuan F,Liu J

更新日期：2020-02-10 00:00:00

abstract：:Non-healing fractures constitute a serious clinical problem. HIF-1α is a crucial regulator in response to hypoxia and is proven to be pivotal in bone growth; however, the mechanism still needs further research. In this study, iTRAQ was used to study the effects of two HIF-1α inducers on the expression of proteins in M...

journal_title：Journal of proteomics

authors： Chen C,Hao X,Geng Z,Wang Z

更新日期：2020-01-16 00:00:00