解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:OBJECTIVE:This study aimed to observe the effect of glutamine (Gln) on brain damage in septic rats and explore its possible mechanism. METHODS:Ninety-three Sprague-Dawley rats were randomly divided into five groups: sham operation group, sepsis group, Gln-treated group, quercetin/Gln-treated group, and alloxan/Gln-tre...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001582
更新日期:2021-01-18 00:00:00
abstract::Ischemic stroke is the most frequent cause of long-term morbidity and mortality in the elderly worldwide. Mild hypothermia (32-35°C) has been found to have a neuroprotective effect against ischemic stroke. However, the protective mechanisms remain unclear. In the present study, we explore the neuroprotective effect of...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001593
更新日期:2021-01-18 00:00:00
abstract:OBJECTIVE:Birdsong sounds are often used to inform visually-challenged people about the presence of basic infrastructures, and therefore need to be salient in noisy urban environments. How salient sounds are processed in the brain could inform us about the optimal birdsong in such environments. However, brain activity ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001563
更新日期:2021-01-13 00:00:00
abstract::MicroRNAs (miRNAs) play important roles in drug tolerance and regulating pain. The purpose of the present study is to explore the regulatory mechanism of miR-124-3p on dezocine tolerance against pain in a rat model. The expression of miR-124-3p and TRAF6 in spinal cord of rats was detected by quantitative reverse-tran...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001559
更新日期:2021-01-06 00:00:00
abstract::The purpose of the present study was to determine the cortical areas contributing to the influence of the previous movement on the current movement. Right-handed healthy human participants abducted and then adducted the left index finger in response to a start cue. Twenty consecutive trials with 10 s intertrial interv...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001578
更新日期:2020-12-30 00:00:00
abstract::Spinal cord injury (SCI) causes motor dysfunction and depression, which hinders the recovery of motor function. Body weight-supported treadmill training (BWSTT) should be considered an effective method for functional rehabilitation after SCI, as it is an efficacious intervention in healthcare with no side effects. Bec...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001543
更新日期:2020-12-16 00:00:00
abstract:OBJECTIVE:The traditional Chinese medicine, Dendrobium nobile Lindl. polysaccharides (DNLP), reportedly has neuroprotective effects. However, its effects following ischemic stroke remain unclear. This study aimed to explore the role and mechanism of DNLP in experimental models of inflammation and apoptosis. METHODS:In...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001562
更新日期:2020-12-14 00:00:00
abstract::Neuroblastoma is an important problem in children. Long noncoding RNAs (lncRNAs) exhibit important roles in tumorigenicity of neuroblastoma. However, the role and mechanism of lncRNA small nucleolar RNA host gene 16 (SNHG16) in neuroblastoma tumorigenicity remain poorly understood. Forty-six neuroblastoma samples and ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001537
更新日期:2020-12-09 00:00:00
abstract::Inhibitory deficits are one of the predominant causes of cognitive aging. This study examined age-related changes in response inhibition. In this study, young and older participants performed a bimanual/bipedal response inhibition task while we measured their brain activity via functional near-infrared spectroscopy. P...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001516
更新日期:2020-10-07 00:00:00
abstract::Calcitonin gene-related peptide (CGRP) and adrenomedullin are structurally similar neuropeptides acting as potent vasodilators of blood pressure and mediator of inflammation in skin. Revealing the expression pattern of their common receptor-Calcitonin gene-related peptide receptor (Calcrl) in their targeted cells is i...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001497
更新日期:2020-08-05 00:00:00
abstract::Correcting for eddy currents, movement-induced distortion and gradient inhomogeneities is imperative when processing diffusion MRI (dMRI) data, but is highly computing resource-intensive. Recently, Compute Unified Device Architecture (CUDA) was implemented for the widely-used eddy-correction software, 'eddy', which re...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001475
更新日期:2020-07-10 00:00:00
abstract::The mammalian neocortex is composed of six major layers of neurons. Each group of neurons in the cortical layers has distinct characteristics based on the expression of specific genes and connectivity patterns of neural circuits. Neuronal subtype transition and regional identity acquisition are established by temporal...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001479
更新日期:2020-07-10 00:00:00
abstract::To compare the diagnostic value of T1-inversion recovery sequence (T1 IR) to that of a T2-sequence with contrast inversion (T2 CI) in the investigation of heterotopias. In this study, we processed a contrast-inverted copy of our coronal T2-sequence of 21 patients with subependymal and subcortical heterotopias on an on...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001463
更新日期:2020-06-07 00:00:00
abstract::Distracted driving remains a leading factor in fatal motor vehicle crashes, particularly in young drivers. Due to ongoing neuromaturation, attention capabilities are changing and improving throughout young adulthood. Here, we sought to bridge neuroscience with driving simulation by evaluating the effects of driving on...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001451
更新日期:2020-05-22 00:00:00
abstract::Exosomes derived from Schwann cells have been known to have a variety of functions in the development and repair of the peripheral nervous system, and cyclic AMP (cAMP) is a key inducer of Schwann cell differentiation. In the present study, we aimed to study the effect of exosomes derived from differentiated Schwann c...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001435
更新日期:2020-05-07 00:00:00
abstract::The neuroprotective effects of netrin-1 after spinal cord injury and its specific molecular mechanisms have not been elucidated. In our study, Western blot, transferase UTP nick end labeling staining and immunofluorescence staining first showed that netrin-1 significantly decreased the expression levels of caspase-3, ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001441
更新日期:2020-05-07 00:00:00
abstract::Autophagy and neurogenesis play a pivotal role in maintaining cellular homeostasis of neurons in the brain. Endurance exercise (EXE) serves as a potent regulator of both autophagy and neurogenesis in the hippocampus of the brain; however, the underlying molecular mechanisms of the dual expression remains unclear. Thus...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001431
更新日期:2020-04-08 00:00:00
abstract:OBJECTIVE:The current study aims to investigate whether computer generated (CG) expressions of emotion evoke similar emotional appraisal processing in the lateral orbitofrontal cortex (lOFC) compared to real human expressions, as well as how speech cues would influence the processing. METHODS:Functional near-infrared ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001420
更新日期:2020-04-08 00:00:00
abstract:OBJECTIVE:Cervical spondylotic myelopathy is regarded as a chronic, special incomplete spinal cord injury, so the sensory components transmitted to thalamus decreased after distal spinal cord injury, which lead the disturbance of thalamus-cortex circuits, which might explain the alterations of clinical function of cerv...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001346
更新日期:2020-03-25 00:00:00
abstract::Surface texture can be perceived not only from tactile, but also from auditory and visual sensory cues. In our previous psychophysical study, we demonstrated that humans can recognize surface stickiness using only one kind of sensory modality without any difficulty. However, the brain regions that would be activated b...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001419
更新日期:2020-03-25 00:00:00
abstract::Recent study has demonstrated that high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) have the same effect to alleviate β-amyloid pathology in the hippocampus of APPswe/PS1dE9 (APP/PS1) mice. Activation of nucleotide binding and oligomerization domain-like receptor family pyrin d...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001429
更新日期:2020-03-25 00:00:00
abstract::Bilateral voluntary contractions involve functional changes in both primary motor cortices. However how the unilateral voluntary contraction of hand muscles influences the contralateral corticomuscular synchronous oscillations mechanisms remains unclear. In the bimanual tasks, nine healthy subjects were instructed to ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001409
更新日期:2020-03-04 00:00:00
abstract:OBJECTIVE:We sought to determine whether cortical excitability, measured via transcranial magnetic stimulation (TMS), is associated with cognition in healthy individuals and whether gender and education have an impact on this relationship. METHODS:Fifty-four healthy individuals (31 males, mean age = 41.94, SD = 21.98;...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001392
更新日期:2020-03-04 00:00:00
abstract::To clarify possible interaction between the ventral hippocampal cannabinoid CB2 receptors and the cholinergic system in control of the memory process, the effects of cannabinoid and acetylcholine receptor agents on memory consolidation have been investigated in mice. Animals implanted with bilateral cannulas at the CA...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001381
更新日期:2020-01-27 00:00:00
abstract::Hyperactivity of the hypothalamic-pituitary-adrenal axis and impairment of the central corticotropin-releasing factor system are factors in the pathogenesis of depression. Though several antagonists of the corticotropin-releasing factor 1 receptor were effective in the recognized behavioral tests for antidepressant ac...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001331
更新日期:2020-01-08 00:00:00
abstract::Self-renewing neural stem cells and progenitor cells are cell populations that generate radial glial cells and neurons through asymmetric division. Regulation of intracellular pH in stem cells with high metabolic activity is critical for both cell signaling and proliferation. We have recently found that a S0859-inhibi...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001372
更新日期:2020-01-08 00:00:00
abstract::Although a large amount of studies have manifested resting state electroencephalogram oscillatory abnormalities in schizophrenia and their first-degree relatives and in schizotype, the results are far from consistent and no research found any relationship between electroencephalograph (EEG) abnormalities and schizotyp...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001350
更新日期:2019-12-10 00:00:00
abstract::The hypothalamus is a limbic structure involved in the emergence and persistence of major depressive disorder symptoms. Previous studies have indicated that major depressive disorder patients exhibited dysregulation between the hypothalamus and cerebral regions. However, it is still unclear about the exact hypothalami...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001335
更新日期:2019-11-06 00:00:00
abstract::Although accumulating evidence suggests that there are significant anatomical and histological differences between the sulci and gyri of the cerebral cortex, whether there is a difference in the distribution of interneurons between the two cortical regions remains largely unknown. In this study, we systematically comp...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001309
更新日期:2019-10-16 00:00:00
abstract:OBJECTIVES:The aim of this study was to determine the expression level of immunoproteasome and its clinical significance in glioma preliminarily. Furthermore, we studied the function and molecular mechanism of proteasome inhibitor ONX 0912 on glioma cell. MATERIALS AND METHODS:The expression of immunoproteasome in gli...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001320
更新日期:2019-10-16 00:00:00
abstract::Gastrin-releasing peptide plays an important role in regulating the advanced functions of the brain including emotional behavior, learning and memory. What's more, gastrin-releasing peptide levels are also associated with the central nervous system diseases. Our previous study proposed that intraperitoneal injection o...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001324
更新日期:2019-10-16 00:00:00
abstract::Propofol is widely used for induction and maintenance of anaesthesia, which causes a rapid loss of consciousness. So far the mechanisms underlying the effect of propofol are still largely unknown. Here, we found that microinjection of propofol in the lateral hypothalamus caused a significant decrease in wakefulness an...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001292
更新日期:2019-10-09 00:00:00
abstract::Although the self-referential effect was widely supported by several previous studies, there was few event-related potential (ERP) evidence for the encoding mechanism of the self-referential effect. The present study employed ERPs to investigate whether the electrophysiological indices of the encoding processing could...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001303
更新日期:2019-09-04 00:00:00
abstract::Remote ischemic preconditioning (RIPC) is an effective regimen for neuroprotection in ischemic stroke. Exosomes are extracellular vesicles released into the blood, where they can transfer signals throughout the body. Several studies have demonstrated that RIPC leads to many changes in circulating exosomes. However, th...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001280
更新日期:2019-08-14 00:00:00
abstract:OBJECTIVES:There are subclinical neurologic deficits in cirrhotic patients without overt hepatic encephalopathy. We aimed to use F-fluorodeoxyglucose PET/computed tomography to explore the impaired brain glucose metabolism of subclinical hepatic encephalopathy in cirrhosis. METHODS:Thirty-seven patients with hepatitis...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001284
更新日期:2019-08-07 00:00:00
abstract::This study was designed to investigate the expression of transient receptor potential melastatin 3 (TRPM3) and transient receptor potential vanilloid type 4 (TRPV4) in the trigeminal spinal subnucleus caudalis of a rat model of trigeminal neuralgia (TN). The influence of botulinum toxin type A (BTX-A) on the expressio...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001268
更新日期:2019-07-03 00:00:00
abstract::Three SNARE proteins, SNAP-25, syntaxin 1A, and VAMP2 or synaptobrevin 2, constitute the minimal functional machinery needed for the regulated secretion of neurotransmitters. Dynamic changes in the regulated release of neurotransmitters are associated with the induction of long-term plasticity at central synapses. In-...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001258
更新日期:2019-07-03 00:00:00
abstract::Abnormal sleep architecture and white matter hyperintensities (WMHs) may be involved in cognitive impairment. There is little evidence on the connections between WMHs and chronic insomnia disorder (CID). Therefore, we evaluated the severity of WMHs and polysomnography parameters as well as cognitive tests to explore t...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001232
更新日期:2019-06-12 00:00:00
abstract::SCN1A gene mutations are associated with epilepsy and neurodevelopmental disorders. This study aimed to explore the genotype and phenotype spectrum of SCN1A gene related epilepsy. Epileptic patients who were treated in the Children's Hospital of Chongqing Medical University from January 2015 to July 2018 and identifie...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001259
更新日期:2019-06-12 00:00:00
abstract::The aim of this study was to identify differences in structural and functional brain connectivity between poststroke mild and severe motor impairment. Twenty-four chronic stroke patients who underwent resting-state functional MRI and diffusion tensor image were retrospectively included. All patients were classified in...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001247
更新日期:2019-05-01 00:00:00