SNHG16 knockdown inhibits tumorigenicity of neuroblastoma in children via miR-15b-5p/PRPS1 axis.

abstract：:Increased oxidative stress in the brain due to chronic ethanol consumption is known to result in a number of neurodegenerative changes. This study was designed to test whether dietary supplementation of grape polyphenols (GP) can offer protection to the neurodegenerative changes resulting from chronic ethanol consumpt...

journal_title：Neuroreport

authors： Sun GY,Xia J,Draczynska-Lusiak B,Simonyi A,Sun AY

更新日期：1999-01-18 00:00:00

abstract：:Depression is present in a large proportion of patients suffering from chronic pain, and yet the underlying mechanisms remain to be elucidated. Neuroligins (NLs), as a family of cell-adhesion proteins, are involved in synaptic formation and have been linked to various neuropsychiatric disorders. Here, we studied the a...

journal_title：Neuroreport

authors： Pan W,Zhang GF,Li HH,Ji MH,Zhou ZQ,Li KY,Yang JJ

更新日期：2018-07-04 00:00:00

abstract：:Two patterns of neuronal firing, bursting and regular spiking, are observed in the somatosensory cortex of anesthetized rats. The effects of excitatory amino acid receptor agonists and antagonists on these discharge types have been examined in vivo, in order to assess their involvement in the generation of such firing...

journal_title：Neuroreport

authors： Kobayashi T,Nagao T,Fukuda H,Hicks TP,Oka JI

更新日期：1993-06-01 00:00:00

abstract：:The effects of Alzheimer's disease-related beta-amyloid (Abeta) peptides on the N-methyl-D-aspartate (NMDA)-evoked cell firing rate were studied in hippocampal CA1 neurons of the rat. Extracellular single-unit recordings were combined with iontophoretic applications that allowed quantitative analyses of the interactio...

journal_title：Neuroreport

authors： Molnár Z,Soós K,Lengyel I,Penke B,Szegedi V,Budai D

更新日期：2004-07-19 00:00:00

abstract：:The neural origins of the cortical response to rare sensory events remain poorly understood. Using simultaneous event-related potentials and magnetic resonance imaging, we investigated the anatomical profile of regional activity at various processing stages during performance of auditory and visual variants of an oddb...

journal_title：Neuroreport

authors： Rezaie R,Simos PG,Papanicolaou AC,Castillo EM,Moser DC,Passaro AD,Fletcher JM

更新日期：2011-02-16 00:00:00

abstract：:To determine whether EEG synchronization in sleep has a metabolic equivalent, we investigated state-dependent changes in extracellular concentrations of amino acids. In vivo microdialysis studies were performed in the ventroposterolateral (VPL) nuclei of the thalamus of cats during natural slow wave sleep (SWS), wakin...

journal_title：Neuroreport

authors： Kékesi KA,Dobolyi A,Salfay O,Nyitrai G,Juhász G

更新日期：1997-03-24 00:00:00

abstract：:There is abundant psychophysical evidence in humans suggesting the existence of parallel pathways subserving different aspects of vision. However, there is little direct proof of the neural structures underlying the two pathways. We present direct anatomical evidence that in the normal human optic tract fibres are seg...

journal_title：Neuroreport

authors： Tassinari G,Campara D,Balercia G,Chilosi M,Martignoni G,Marzi CA

更新日期：1994-07-21 00:00:00

abstract：:The distribution of histamine H1, H3, dopamine D1 and D2 receptors in the brain was studied by receptor autoradiography using a high-sensitivity and high-resolution imaging plate system. [3H]Pyrilamine, [3H](R)alpha-methyl-histamine, [11C]SCH23390, and [11C]N-methylspiperone (or [11C]YM-09151-2) were used as ligands t...

journal_title：Neuroreport

authors： Yanai K,Ryu JH,Watanabe T,Iwata R,Ido T

更新日期：1992-11-01 00:00:00

abstract：:Freshly dissected and dissociated subventricular zone cells from adult male mice were transplanted into the right cerebral cortex of adult female mice. Host mice were perfused 3 or 7 weeks later. To detect donor male cells, paraffin sections (10 microm) were hybridized in situ with a Y-chromosome-specific probe. Some ...

journal_title：Neuroreport

authors： Harvey AR,Symons NA,Pollett MA,Brooker GJ,Bartlett PF

更新日期：1997-12-22 00:00:00

abstract：:We investigated the brain mechanisms enabling one automatically discriminate phoneme category irrespective of the large inter-speaker variability in the acoustic features of the voices. For this purpose, subjects were presented with 450 different speech stimuli, each uttered by a different speaker, belonging to three ...

journal_title：Neuroreport

authors： Shestakova A,Brattico E,Huotilainen M,Galunov V,Soloviev A,Sams M,Ilmoniemi RJ,Näätänen R

更新日期：2002-10-07 00:00:00

abstract：:This study aimed to investigate effects of observing the own body being touched on the functional topography of the somatosensory homunculus. We used neuromagnetic source imaging to map the topography in primary somatosensory cortex (SI) while manipulating the visibility of a touched hand. Participants were either abl...

journal_title：Neuroreport

authors： Schaefer M,Heinze HJ,Rotte M

更新日期：2008-06-11 00:00:00

abstract：:We investigated the effects of chemical hypoxia on the central pattern generator controlling swimming in stage 42 Xenopus laevis larvae. We recorded motoneuron activity from ventral roots of immobilized tadpoles and evoked swim episodes by brief electrical stimulation of the tail skin. In the presence of the metabolic...

journal_title：Neuroreport

authors： Robertson RM,Björnfors ER,Sillar KT

更新日期：2010-10-06 00:00:00

abstract：:The hypothesis that reactive free radical species (ROS) may contribute to the pathogenesis of Duchenne muscular dystrophy (DMD) has been suggested previously, but experimental data obtained in support of the above have to date proved inconclusive. The recent discovery that nitric oxide synthase (required for muscle re...

journal_title：Neuroreport

authors： Haycock JW,MacNeil S,Jones P,Harris JB,Mantle D

更新日期：1996-12-20 00:00:00

abstract：:GLAST is a glial glutamate transporter; mRNA for a splice variant, GLAST1a, which lacks exon 3, has previously been identified. To detect GLAST1a protein, we generated antibodies against a peptide sequence encompassing the splice site. We demonstrate by Western blotting and immunocytochemistry the expression of GLAST1...

journal_title：Neuroreport

authors： Macnab LT,Williams SM,Pow DV

更新日期：2006-12-18 00:00:00

abstract：:Distracted driving remains a leading factor in fatal motor vehicle crashes, particularly in young drivers. Due to ongoing neuromaturation, attention capabilities are changing and improving throughout young adulthood. Here, we sought to bridge neuroscience with driving simulation by evaluating the effects of driving on...

journal_title：Neuroreport

authors： Banz BC,Wu J,Camenga DR,Mayes LC,Crowley MJ,Vaca FE

更新日期：2020-05-22 00:00:00

abstract：:The functional integrity of the 'on' and 'off' neurovisual pathways has been examined in the central visual fields of normal (n = 13), glaucomatous (n = 21) and ocular hypertensive (n = 21) individuals. The detection thresholds to light increments (onsets = bright spots) and light decrements (offsets = dark spots) on ...

journal_title：Neuroreport

authors： Mutlukan E

更新日期：1993-09-03 00:00:00

abstract：:Male Bengalese finches sing complex song sequences during courtship. To examine the female perception of sequence complexity, we tested female auditory processing with respect to sequential differences in the caudomedial nidopallium and caudomedial mesopallium. Repeated song presentations caused lower expression of th...

journal_title：Neuroreport

authors： Kato Y,Kato M,Hasegawa T,Okanoya K

更新日期：2010-04-21 00:00:00

abstract：:Consumers often rely on observable cues that hint at the hidden quality of a product. The aim of this study was to investigate brain activities associated with the country-of-origin (COO) effect and consumer evaluation of a product design. Electroencephalogram recordings were used to observe event-related brain potent...

journal_title：Neuroreport

authors： Min BK,Cho K,Sung J,Cho E

更新日期：2014-03-05 00:00:00

abstract：:This study was performed to test the hypothesis that diminution in the preovulatory luteinizing hormone (LH) surge in middle-aged (MA) rats may be related to altered activity in nitric oxide (NO)ergic neurons. To begin to test the hypothesis, gene expression of hypothalamic NO synthase (NOS), the enzyme that catalyzes...

journal_title：Neuroreport

authors： Sahu A

更新日期：1998-12-21 00:00:00

abstract：:When two cylinders are passively moved in-phase on the volar surface of the right second and third fingers, human subjects estimate the stimuli to originate from one object, whereas two separate objects are estimated for out-of-phase stimuli. While five blindfolded subjects performed this estimation task, brain activi...

journal_title：Neuroreport

authors： Kitada R,Kochiyama T,Hashimoto T,Naito E,Matsumura M

更新日期：2003-04-15 00:00:00

abstract：:Hypoxia-inducible factor-1 (HIF-1) regulates the expression of neuroprotective genes such as erythropoietin (EPO). We investigated the mechanism by which zinc, an excitotoxin-like metal, regulates HIF-1 under hypoxic conditions in astrocytes. In hypoxic LN215 cells, HIF-1alpha stabilized and accumulated in the nucleus...

journal_title：Neuroreport

authors： Kim I,Kim CH,Seo GH,Kim HS,Lee J,Kim DG,Ahn YS

更新日期：2008-07-02 00:00:00

abstract：:Two [O(15)] PET studies assessed sex differences regional brain activation in the recognition of emotional stimuli. Study I revealed that the recognition of emotion in visual faces resulted in bilateral frontal activation in women, and unilateral right-sided activation in men. In study II, the complexity of the emotio...

journal_title：Neuroreport

authors： Hall GB,Witelson SF,Szechtman H,Nahmias C

更新日期：2004-02-09 00:00:00

abstract：:In the present study, we tested the hypothesis that interleukin (IL)-10 down-regulates human microglial cell IL-8 release by inhibiting activation of nuclear factor kappa B (NF-kappaB). Immunohistochemical staining demonstrated that IL-10 markedly suppressed lipopolysaccharide (LPS)- and IL-1beta-stimulated IL-8 expre...

journal_title：Neuroreport

authors： Ehrlich LC,Hu S,Peterson PK,Chao CC

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to determine the expression level of immunoproteasome and its clinical significance in glioma preliminarily. Furthermore, we studied the function and molecular mechanism of proteasome inhibitor ONX 0912 on glioma cell. MATERIALS AND METHODS:The expression of immunoproteasome in gli...

journal_title：Neuroreport

authors： Min L,Zeng X,Li B,Tao B,Shi J,Zhang W,Sun Q,Jing C,Wang X

更新日期：2019-10-16 00:00:00

abstract：:GABAA receptors mediate the inhibition of somatostatin release in hypothalamic neurones. To study the possible effect of GABA on somatostatin biosynthesis, somatostatin and preprosomatostatin mRNA levels were evaluated after exposure of hypothalamic neurones to muscimol or bicuculline. Muscimol (50 microM) decreased p...

journal_title：Neuroreport

authors： Rage F,Jalaguier S,Rougeot C,Tapia-Arancibia L

更新日期：1993-03-01 00:00:00

abstract：:The pattern of immunoreactivity for amyloid precursor (APP) and B-cell lymphoma protooncogene (Bcl-2) proteins in the rat retina was studied after intravitreal injection of basic fibroblast growth factor (bFGF) or transforming growth factor-beta (TGFbeta). In normal control retinas, intense immunostaining of APP and B...

journal_title：Neuroreport

authors： Chen ST,Jen A,Gentleman SM,Jen LS

更新日期：1999-02-25 00:00:00

abstract：:Compartmental models of thalamic reticular (RE) neurons were investigated based on current-clamp and voltage-clamp data. Spontaneous oscillations in the model arise from the interaction between inhibitory synaptic currents and the rebound burst of RE cells. These oscillations critically depend on the level of the rest...

journal_title：Neuroreport

authors： Destexhe A,Contreras D,Sejnowski TJ,Steriade M

更新日期：1994-11-21 00:00:00

abstract：:In rapid serial visual presentation of pictures, an early event-related brain potential component shows enlarged negativity over occipital regions for emotional pictures compared with neutral pictures. The present study examined whether the processing of emotional target pictures varies as a function of stimulus repet...

journal_title：Neuroreport

authors： Schupp HT,Stockburger J,Codispoti M,Junghöfer M,Weike AI,Hamm AO

更新日期：2006-03-20 00:00:00

abstract：:Upon perfusion with Mg2+-free artificial cerebrospinal fluid (ACSF) organotypic hippocampal slice cultures develop seizure-like events and tonic recurrent discharges in which areas CA3 and CA1 and, in contrast to acute slices, also the dentate gyrus (DG) participate. Using the fluorescent dye propidium iodide (PI) we ...

journal_title：Neuroreport

authors： Kovács R,Gutiérrez R,Kivi A,Schuchmann S,Gabriel S,Heinemann U

更新日期：1999-02-05 00:00:00

abstract：:We investigated the spatio-temporal brain activity on the time scale of several milliseconds related to the mental rotation task requiring judgements of hand orientation, using a whole-cortex MEG (magnetoencephalography) system. Neuronal activity in the visual cortex was observed approximately 100-200 ms from stimulus...

journal_title：Neuroreport

authors： Kawamichi H,Kikuchi Y,Endo H,Takeda T,Yoshizawa S

更新日期：1998-04-20 00:00:00