Magno- and parvocellular pathways are segregated in the human optic tract.

Abstract:

:There is abundant psychophysical evidence in humans suggesting the existence of parallel pathways subserving different aspects of vision. However, there is little direct proof of the neural structures underlying the two pathways. We present direct anatomical evidence that in the normal human optic tract fibres are segregated according to size. Large axons, likely to correspond to the magnocellular pathway of non-human primates, take a more ventral and superficial course than the smaller axons belonging to the parvocellular pathway. This anatomical segregation not only reinforces the hypothesis of parallel pathways but, more importantly, offers a unique opportunity for studying the psychophysical effects of selective damage to one or the other fibre contingent.

journal_name

Neuroreport

journal_title

Neuroreport

authors

Tassinari G,Campara D,Balercia G,Chilosi M,Martignoni G,Marzi CA

doi

10.1097/00001756-199407000-00005

subject

Has Abstract

pub_date

1994-07-21 00:00:00

pages

1425-8

issue

12

eissn

0959-4965

issn

1473-558X

journal_volume

5

pub_type

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