Abstract:
:The functional integrity of the 'on' and 'off' neurovisual pathways has been examined in the central visual fields of normal (n = 13), glaucomatous (n = 21) and ocular hypertensive (n = 21) individuals. The detection thresholds to light increments (onsets = bright spots) and light decrements (offsets = dark spots) on a uniform background were determined in each eye and the visual field scores were calculated for each of the subjects. Light offsets detected the presence of glaucomatous visual loss and also revealed significant early visual deficits which were missed by the conventional light onset stimuli. This study indicates that 'off-pathway' evaluation with light offsets can be used for the assessment of the functional integrity of the visual system and may reveal sub-clinical early glaucomatous optic neuropathy.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Mutlukan Esubject
Has Abstractpub_date
1993-09-03 00:00:00pages
1159-62issue
10eissn
0959-4965issn
1473-558Xjournal_volume
4pub_type
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