Temporal structure of implicit motor imagery in visual hand-shape discrimination as revealed by MEG.


:We investigated the spatio-temporal brain activity on the time scale of several milliseconds related to the mental rotation task requiring judgements of hand orientation, using a whole-cortex MEG (magnetoencephalography) system. Neuronal activity in the visual cortex was observed approximately 100-200 ms from stimulus onset, and that in inferior parietal lobe followed (after 200 ms). Both of these activities showed a contralateral dominance to visual stimulus hemifield. Premotor activity started later than the inferior parietal lobe activity, and these activities partially overlapped. Activity in primary motor and/or motosensory areas was observed in some subjects. The whole-cortex neuromagnetic measurements provided the time course of activity in the human brain associated with the implicit motor imagery: visual cortex-->inferior parietal lobe<-->premotor cortex. This process is considered to be the transformation process of retinotopic locations into a body-centered reference frame necessary for the mental rotation task.






Kawamichi H,Kikuchi Y,Endo H,Takeda T,Yoshizawa S




Has Abstract


1998-04-20 00:00:00












  • Primary auditory cortex activation by visual speech: an fMRI study at 3 T.

    abstract::Recent studies have yielded contradictory evidence on whether visual speech perception (watching articulatory gestures) can activate the human primary auditory cortex. To circumvent confounds due to inter-individual anatomical variation, we defined our subjects' Heschl's gyri and assessed blood oxygenation-dependent s...


    pub_type: 杂志文章


    authors: Pekkola J,Ojanen V,Autti T,Jääskeläinen IP,Möttönen R,Tarkiainen A,Sams M

    更新日期:2005-02-08 00:00:00

  • Involvement of vision in tool use in crow.

    abstract::Birds are capable of dexterous sensory-motor activities such as tool use. Reaching is a crucial component of tool use and is a vision-guided behavior in primates, in which arm movement is monitored online in a stable visual frame. However, vision-guided reaching in primates is enabled by anatomical separation of the h...


    pub_type: 杂志文章


    authors: Kanai M,Matsui H,Watanabe S,Izawa E

    更新日期:2014-09-10 00:00:00

  • Comparison of visual--vestibular interaction in insulin-dependent and non-insulin-dependent diabetes mellitus.

    abstract::We compared various measures of visual-vestibular interaction in subjects with insulin-dependent diabetes mellitus (IDDM) or non-insulin-dependent diabetes mellitus (NIDDM), as well as non-diabetic controls. Subjects with IDDM exhibited significantly greater postural sway than controls on those conditions in the Clini...


    pub_type: 杂志文章


    authors: Darlington CL,Erasmus J,Nicholson M,King J,Smith PF

    更新日期:2000-02-28 00:00:00

  • Population coding of movement dynamics by cerebellar Purkinje cells.

    abstract::In order to accomplish desired movements, the nervous system must specify the movement dynamics: it must provide a signal that compensates for the mechanical constraints encountered during movement. Here we tested whether the population activity of Purkinje cells in the cerebellum specifies the dynamics for pursuit ey...


    pub_type: 杂志文章


    authors: Krauzlis RJ

    更新日期:2000-04-07 00:00:00

  • Physiology of morphologically identified cells of the bullfrog fungiform papilla.

    abstract::Voltage-gated ionic current and the response to quinine were studied on the four types of morphologically identified taste cells of the bullfrog fungiform papilla by whole-cell patch clamp recording with a Lucifer yellow-filled pipette. Dye-coupled type Ia cells (mucous cells) did not show voltage-activated currents. ...


    pub_type: 杂志文章


    authors: Takeuchi H,Tsunenari T,Kurahashi T,Kaneko A

    更新日期:2001-09-17 00:00:00

  • The pattern and distribution of calcitonin gene-related peptide (CGRP) terminals in the rat dorsal following neonatal peripheral inflammation.

    abstract::Neonatal peripheral inflammation has been shown to alter the neural circuitry of the spinal cord in adult rats. However, the temporal and spatial changes in the distribution of primary afferent terminals immediately following a neonatal inflammatory stimulus remains unclear. In the present study we found that intrapla...


    pub_type: 杂志文章


    authors: Ling QD,Chien CC,Wen YR,Fu WM,Sun WZ

    更新日期:2003-10-27 00:00:00

  • Voice onset time encoding in patients with left and right cochlear implants.

    abstract::Stop-consonant discrimination was investigated in normal-hearing listeners and cochlear-implanted patients (CIP) by recording auditory evoked potentials (AEPs) to /b epsilon/ and /p epsilon/ syllables. This study demonstrates that: (i) AEPs show time-locked components that mimic the temporal structure of the stimuli, ...


    pub_type: 杂志文章


    authors: Roman S,Canévet G,Lorenzi C,Triglia JM,Liégeois-Chauvel C

    更新日期:2004-03-22 00:00:00

  • Subarachnoid hemorrhage induces c-fos, c-jun and hsp70 mRNA expression in rat brain.

    abstract::To detect stress responses of the brain to subarachnoid hemorrhage (SAH), we investigated the expression of immediate early genes (IEGs) and hsp70 mRNA by in situ hybridization. Experimental SAH was produced in 49 rats by endovascular penetration. We also monitored the intracranial pressure (ICP) changes. The genes c-...


    pub_type: 杂志文章


    authors: Harada S,Kamiya K,Masago A,Iwata A,Yamada K

    更新日期:1997-10-20 00:00:00

  • Localization of mGluR4 protein in the rat cerebral cortex and hippocampus.

    abstract::The cellular distribution of the rat metabotropic glutamate receptor type 4 (mGluR4) was examined in the adult rat cerebral cortex and hippocampus. Antibodies were raised against amino acid residues located in the extracellular amino terminal domain that is common to both the mGluR4a and mGluR4b splice variants, and u...


    pub_type: 杂志文章


    authors: Phillips T,Makoff A,Brown S,Rees S,Emson P

    更新日期:1997-10-20 00:00:00

  • Chronic activation of spinal adenosine A1 receptors results in hypersensitivity.

    abstract::Spinally administered adenosine reduces hypersensitivity in animals and humans with nerve injury, but also causes transient pain in humans and reduces tonic inhibition in spinal neurons. Nerve injury results in increased tonic spinal cord adenosine A1 receptor activation, consistent with a role for adenosine to genera...


    pub_type: 杂志文章


    authors: Martin TJ,Eisenach JC,Misler J,Childers SR

    更新日期:2006-10-23 00:00:00

  • The beta-amyloid epitope masking activity in human brain is identified as albumin.

    abstract::Human brain homogenate proteins were analyzed for binding and processing activity in relation to brain beta-amyloid precursor protein (APP). The homogenate was purified by arginine-Sepharose 4B affinity chromatography, which traps proteins with affinity to certain groups of arginine residue, such as serine proteases a...


    pub_type: 杂志文章


    authors: Matsumoto A,Minami M,Matsumoto R

    更新日期:1997-10-20 00:00:00

  • HIV-derived protein gp120 suppresses P3 potential in rats: potential implications in HIV-associated dementia.

    abstract::Between 20 and 30% of AIDS patients have neurological symptoms characterized by motor impairment, memory loss and progressive dementia. Previous studies have implicated the HIV derived gp120, which produces behavioral deficits and electrophysiological alterations in rats. The goal of the present study was to describe ...


    pub_type: 杂志文章


    authors: Galicia O,Sánchez-Alavez M,Díaz-Ruíz O,Sánchez Narváez F,Elder JH,Navarro L,Prospéro-García O

    更新日期:2000-04-27 00:00:00

  • Reduced prefrontal hemodynamic response in children with ADHD during the Go/NoGo task: a NIRS study.

    abstract::The current study examined the hemodynamic response during the Go/NoGo task in children with/without attention deficit/hyperactivity disorder (ADHD). Using near-infrared spectroscopy, oxy-Hb and deoxy-Hb concentration changes in the frontal areas were compared during the conditions with/without inhibitory demand. Comp...


    pub_type: 杂志文章


    authors: Inoue Y,Sakihara K,Gunji A,Ozawa H,Kimiya S,Shinoda H,Kaga M,Inagaki M

    更新日期:2012-01-25 00:00:00

  • Activation of metabotropic glutamate receptors delays apoptosis of chick embryonic motor neurons in vitro.

    abstract::Glutamatergic excitotoxicity has been implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS). However, activation of metabotropic glutamate receptors (mGluRs) is neuroprotective in several paradigms. We therefore tested the effect of selective mGluR agonists on cultured chick embryonic motor neurons. Ac...


    pub_type: 杂志文章


    authors: Anneser JM,Horstmann S,Weydt P,Borasio GD

    更新日期:1998-06-22 00:00:00

  • Corpus callosum: musician and gender effects.

    abstract::Previously we found that musicians have significantly larger anterior corpus callosum (CC). In the current study, we intended to replicate and extend our previous results using a new and larger sample of gender-matched subjects (56 right-handed professional musicians and 56 age- and handedness-matched controls). We fo...


    pub_type: 杂志文章


    authors: Lee DJ,Chen Y,Schlaug G

    更新日期:2003-02-10 00:00:00

  • The serotonin transporter is a potential susceptibility factor for bipolar affective disorder.

    abstract::The serotonin transporter is a strong candidate for aetiological involvement in affective disorders and psychosis. We analysed a VNTR in intron 2 of the human serotonin transporter gene (hSERT) for allelic association with bipolar affective disorder, unipolar depression and schizophrenia. An increased frequency of all...


    pub_type: 杂志文章


    authors: Collier DA,Arranz MJ,Sham P,Battersby S,Vallada H,Gill P,Aitchison KJ,Sodhi M,Li T,Roberts GW,Smith B,Morton J,Murray RM,Smith D,Kirov G

    更新日期:1996-07-08 00:00:00

  • Opioid receptors in the human cerebellum: evidence from [11C]diprenorphine PET, mRNA expression and autoradiography.

    abstract::Little is known regarding opioid receptors in the human cerebellum. The present [11C]diprenorphine PET study investigated opioid receptor binding in the human cerebellum in vivo, and showed a differential binding level in cerebellar cortex, vermis and dentate nuclei. The additional study in vitro of opioid receptors i...


    pub_type: 杂志文章


    authors: Schadrack J,Willoch F,Platzer S,Bartenstein P,Mahal B,Dworzak D,Wester HJ,Zieglgänsberger W,Tölle TR

    更新日期:1999-02-25 00:00:00

  • Two novel (M233T and R278T) presenilin-1 mutations in early-onset Alzheimer's disease pedigrees and preliminary evidence for association of presenilin-1 mutations with a novel phenotype.

    abstract::Eleven early-onset dementia families, all with affected individuals who have either presented clinical symptoms of early onset familial Alzheimer's disease (EOFAD) or have been confirmed to have EOFAD by autopsy, and two early onset cases with biopsy-confirmed AD pathology, were screened for missense mutations in the ...


    pub_type: 杂志文章


    authors: Kwok JB,Taddei K,Hallupp M,Fisher C,Brooks WS,Broe GA,Hardy J,Fulham MJ,Nicholson GA,Stell R,St George Hyslop PH,Fraser PE,Kakulas B,Clarnette R,Relkin N,Gandy SE,Schofield PR,Martins RN

    更新日期:1997-04-14 00:00:00

  • Human short latency cortical responses to somatosensory stimulation. A high resolution EEG study.

    abstract::Human short-latency cortical responses to median nerve stimulation were investigated with a new high resolution electroencephalography technology that markedly enhanced spatial details of somatosensory-evoked potentials (SEPs). Maximum amplitude potentials were estimated over contralateral and/or frontal-mesial scalp ...


    pub_type: 临床试验,杂志文章


    authors: Urbano A,Babiloni F,Babiloni C,Ambrosini A,Onorati P,Rossini PM

    更新日期:1997-10-20 00:00:00

  • Neural activity mapping with inducible transcription factors.

    abstract::Neurons respond to extracellular stimulation by modulating the expression of certain immediate-early genes. Inducible transcription factors (ITFs), such as c-Fos and Zif268, are coded by this class of gene and are among the first proteins to appear. The rapid accumulation of these products combined with histological m...


    pub_type: 杂志文章,评审


    authors: Chaudhuri A

    更新日期:1997-09-08 00:00:00

  • Melatonin inhibits oxytocin and vasopressin release from the neurointermediate lobe of the hamster pituitary.

    abstract::The aim of this investigation was to study whether melatonin affects the release of oxytocin and vasopressin by the pituitary neurointermediate lobe of the Syrian hamster in vitro. The effect of melatonin was studied on the unstimulated (pre- and post-K+ -stimulated) release of oxytocin and vasopressin and on the resp...


    pub_type: 杂志文章


    authors: Juszczak M,Debeljuk L,Bartke A,Stempniak B

    更新日期:1995-12-15 00:00:00

  • Neuroendocrine regulation of growth hormone secretion in sheep. VI. Intracerebroventricular administration of galanin.

    abstract::The effects of intracerebroventricular (i.c.v.) administration of galanin on plasma growth hormone (GH) concentrations and its possible mechanism of action have been examined in sheep. Galanin administration icv resulted in a dose-dependent increase in plasma GH concentrations (p < 0.01). Concurrent administration of ...


    pub_type: 杂志文章


    authors: Spencer GS,Berry CJ,Bass JJ

    更新日期:1994-01-12 00:00:00

  • Serum zinc, senile plaques, and neurofibrillary tangles: findings from the Nun Study.

    abstract::Zinc appears to have a role in binding amyloid precursor protein in vitro, but it is not known whether zinc plays a role in senile plaque formation in vivo in humans. Serum zinc concentrations were available from 12 sisters who died in the Nun Study, a longitudinal study of aging and Alzheimer's disease. Fasting serum...


    pub_type: 杂志文章


    authors: Tully CL,Snowdon DA,Markesbery WR

    更新日期:1995-11-13 00:00:00

  • Schwann cell remyelination is not replaced by oligodendrocyte remyelination following ethidium bromide induced demyelination.

    abstract::Demyelinated CNS axons can be remyelinated by Schwann cells. A recent study concluded that with time Schwann cell remyelination is replaced by oligodendrocyte remyelination [9]. To examine this, the extent of Schwann cell and oligodendrocyte remyelination at 4, 6.5 and 24 weeks was determined for ethidium bromide lesi...


    pub_type: 杂志文章


    authors: Gilson JM,Blakemore WF

    更新日期:2002-07-02 00:00:00

  • Substrate-bound carbohydrates stimulate signal transduction and neurite outgrowth in an olfactory neuron cell line.

    abstract::Subpopulations of olfactory receptor neurons, which are dispersed throughout the olfactory neuroepithelium, express specific cell surface carbohydrates and project to discrete regions of the olfactory bulb. Cell surface carbohydrates such as N-acetyl-lactosamine have been postulated to mediate sorting and selective fa...


    pub_type: 杂志文章


    authors: Puche AC,Bartlett PF,Key B

    更新日期:1997-10-20 00:00:00

  • Apoptosis in rat hippocampal dentate gyrus after intraventricular colchicine.

    abstract::The aim of this study was to examine the neurodegenerative effects of intraventricular colchicine on granule cells of the hippocampal dentate gyrus and to characterise the modality of neuronal cell death. Male Sprague-Dawley rats were killed 24 hours after a single injection of colchicine into the third ventricle and ...


    pub_type: 杂志文章


    authors: Ceccatelli S,Ahlbom E,Diana A,Zhivotovsky B

    更新日期:1997-12-01 00:00:00

  • Dose-response of rt-PA and its combination with aspirin in a rat embolic stroke model.

    abstract::The efficacy and safety of thrombolysis with different dose regimens of recombinant tissue plasminogen activator (rt-PA) and its combination with aspirin was tested in an embolic stroke model. In rats the carotid territory was embolized with a single clot formed in a polyethylene tube and washed with saline. Fifteen m...


    pub_type: 杂志文章


    authors: Overgaard K,Sereghy T,Pedersen H,Boysen G

    更新日期:1992-10-01 00:00:00

  • Limb flexion reflex-related areas in human cerebellum.

    abstract::Numerous studies have shown that the cerebellum is involved in classical conditioning of specific aversive reactions. Only few studies, however, have examined the exact localization of cerebellar areas involved in the control of unconditioned reflex responses. The present study investigated cerebellar areas, which are...


    pub_type: 杂志文章


    authors: Maschke M,Erichsen M,Drepper J,Jentzen W,Müller SP,Kolb FP,Diener HC,Timmann D

    更新日期:2002-12-03 00:00:00

  • Spontaneous saccades under different visual conditions in the pigeon.

    abstract::Spontaneous saccades of both eyes were recorded in head-restrained pigeons placed in 6 different visual conditions (darkness and biocular, uniocular, frontal or lateral viewing). Most saccades (95%) were biocular and directed forward (around the beak axis) and backward (around the horizontal line). In the dark, the pr...


    pub_type: 杂志文章


    authors: Lemeignan M,Sansonetti A,Gioanni H

    更新日期:1992-01-01 00:00:00

  • Daily methylphenidate administration attenuates c-fos expression in the striatum of prepubertal rats.

    abstract::Methylphenidate (Ritalin) is a psychostimulant drug used to treat children with attention deficit hyperactivity disorder. Despite its widespread and increasing clinical use, little is known about the long-term consequences of drug treatment. We compared the effects of a single injection of methylphenidate with that of...


    pub_type: 杂志文章


    authors: Chase TD,Brown RE,Carrey N,Wilkinson M

    更新日期:2003-04-15 00:00:00