Dispositional pessimism and amygdala activity: a PET study in healthy volunteers.

Abstract:

:The present study used scores from Seligman's Attribution Style Questionnaire and [15O] water positron emission tomographic measurements of regional cerebral blood flow (rCBF) to investigate the relation between individual differences in dispositional pessimism and amygdala activity. During scanning 13 healthy non-snake-phobic females passively viewed a snake videotape. Using one-tailed tests, significant negative correlations were evident between pessimism scores, with low scores reflecting relatively more pessimism, and right (r=-0.60; p=0.014) and left amygdala rCBF (r=-0.53; p=0.032). These results extend previous neuroimaging findings in healthy subjects indicating a role for the amygdala in transient negative emotional states, and suggest that this multimodal brain region also is involved in more durable negative affects such as dispositional pessimism.

journal_name

Neuroreport

journal_title

Neuroreport

authors

Fischer H,Tillfors M,Furmark T,Fredrikson M

doi

10.1097/00001756-200106130-00024

subject

Has Abstract

pub_date

2001-06-13 00:00:00

pages

1635-8

issue

8

eissn

0959-4965

issn

1473-558X

journal_volume

12

pub_type

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