Cerebral ischemia/reperfusion injury in rat brain: effects of naloxone.

abstract：:In this study, we examined the expression of insulin-like growth factor I (IGF-I) and its receptor (IGF-IR) in dorsal root ganglia (DRG) neurons in two rodent models of nerve injury: sciatic nerve axotomy and streptozotocin-induced (STZ) painful diabetic neuropathy. We demonstrate that IGF-I and its receptor are prefe...

journal_title：Neuroreport

authors： Craner MJ,Klein JP,Black JA,Waxman SG

更新日期：2002-09-16 00:00:00

abstract：:We investigated the brain mechanisms enabling one automatically discriminate phoneme category irrespective of the large inter-speaker variability in the acoustic features of the voices. For this purpose, subjects were presented with 450 different speech stimuli, each uttered by a different speaker, belonging to three ...

journal_title：Neuroreport

authors： Shestakova A,Brattico E,Huotilainen M,Galunov V,Soloviev A,Sams M,Ilmoniemi RJ,Näätänen R

更新日期：2002-10-07 00:00:00

abstract：:Autophosphorylation of the alpha-isoform of Ca2+/calmodulin-dependent kinase II switches the kinase into an autonomous activity mode. This molecular switch is important for hippocampal long-term memory formation, which requires de novo gene transcription and protein synthesis. Here, we have studied whether auto-phosph...

journal_title：Neuroreport

authors： von Hertzen LS,Giese KP

更新日期：2005-08-22 00:00:00

abstract：:We injected neural tracers into the lateral funiculus of the spinal cord in order to relate the sites of origin of the spinal projections from the mesial cortical surface with the cytoarchitectonic organization of this region. We found a close correlation between the origin sites and density of corticospinal projectio...

journal_title：Neuroreport

authors： Luppino G,Matelli M,Camarda R,Rizzolatti G

更新日期：1994-12-20 00:00:00

abstract：:We studied whether 5-month-old to 8-month-old infants process faces in a size-invariant manner by applying the fNIRS-adaptation paradigm used in our previous study. We used near-infrared spectroscopy to measure hemodynamic responses in the temporal regions of infants' brains during the repeated presentation of an iden...

journal_title：Neuroreport

authors： Kobayashi M,Otsuka Y,Kanazawa S,Yamaguchi MK,Kakigi R

更新日期：2012-12-05 00:00:00

abstract：:The human kallikrein gene family consists of 15 serine proteases. We examined the expression of the kallikrein genes in human cerebral cortex and hippocampus by RT-PCR and compared their expression between Alzheimer's disease (AD) and control tissue. KLK1, 4, 5, 6, 7, 8, 10, 11, 13 and 14 are expressed in both cerebra...

journal_title：Neuroreport

authors： Shimizu-Okabe C,Yousef GM,Diamandis EP,Yoshida S,Shiosaka S,Fahnestock M

更新日期：2001-08-28 00:00:00

abstract：:Ca2+/calmodulin-dependent protein kinase II (CaMKII) plays critical roles in neurotransmission, synaptic plasticity, learning and memory. The aim of this study was to examine, by in situ hybridization, prefrontal cortical expression of CaMKII alpha mRNA in postmortem brains of unipolar, bipolar, schizophrenic, and con...

journal_title：Neuroreport

authors： Xing G,Russell S,Hough C,O'Grady J,Zhang L,Yang S,Zhang LX,Post R

更新日期：2002-03-25 00:00:00

abstract：:The neural foundation of age-related declines in prospective memory was explored using event-related brain potentials (ERPs). Consistent with previous research, a decline in the efficiency of prospective memory was observed in older adults that reflected a decrease in veridical prospective responses and an increase in...

journal_title：Neuroreport

authors： West R,Covell E

更新日期：2001-09-17 00:00:00

abstract：:We investigated the spatio-temporal brain activity on the time scale of several milliseconds related to the mental rotation task requiring judgements of hand orientation, using a whole-cortex MEG (magnetoencephalography) system. Neuronal activity in the visual cortex was observed approximately 100-200 ms from stimulus...

journal_title：Neuroreport

authors： Kawamichi H,Kikuchi Y,Endo H,Takeda T,Yoshizawa S

更新日期：1998-04-20 00:00:00

abstract：:(-)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenolic extract in green tea and it has attracted increasing attention for its multiple bioactive effects. However, the mechanisms by which EGCG exerts its neuroprotective actions in Alzheimer's disease (AD) are presently lacking. In the present study, a ...

journal_title：Neuroreport

authors： Guo Y,Zhao Y,Nan Y,Wang X,Chen Y,Wang S

更新日期：2017-07-05 00:00:00

abstract：:Homotopic and isochronic transplantation of the alar plate of the rhombomeres 7 and 8 was performed between chick and quail embryos at the stage of 10-14 somites. Analysis of the graft derivatives in 12-day-old chimeric embryos by means of the quail nucleolar marker showed that the ipsilateral inferior olive is formed...

journal_title：Neuroreport

authors： Ambrosiani J,Armengol JA,Martinez S,Puelles L

更新日期：1996-05-17 00:00:00

abstract：:Salidroside (SDS), a phenylpropanoid glycoside isolated from Rhodiola rosea L., has been reported to be neuroprotective in vitro, which raises the possibility of using SDS as a neuroprotective agent after nerve injuries. In the present study, the possibly beneficial effect of SDS on promoting nerve regeneration after ...

journal_title：Neuroreport

authors： Sheng QS,Wang ZJ,Zhang J,Zhang YG

更新日期：2013-03-27 00:00:00

abstract：:Mammals react to acute hypoxia with an initial augmentation and a secondary depression of the respiratory rhythm generated by brain stem neuronal networks. To investigate the cytosolic level of energy rich phosphorus metabolites during these responses, we developed 31P nuclear magnetic resonance spectroscopy of the br...

journal_title：Neuroreport

authors： Piérard C,Champagnat J,Denavit-Saubie M,Gillet B,Beloeil JC,Guezennec CY,Barrère B,Pérès M

更新日期：1995-12-29 00:00:00

abstract：:This study is to explore the involvement of muscarinic acetylcholine receptors/protein kinase C cascade and the mitogen-activated protein kinase pathway in the effect of huperzine A on the secretory amyloid precursor protein-alpha. Upregulation of secretory amyloid precursor protein-alpha by huperzine A was attenuated...

journal_title：Neuroreport

authors： Yan H,Zhang HY,Tang XC

更新日期：2007-05-07 00:00:00

abstract：:Multiple sclerosis is associated with reduced white matter integrity and deficits in key cognitive processes important for arithmetic. This study examined the relationship between white matter microstructure and academic ability in 31 youths with multiple sclerosis (aged 11-19 years) and 34 demographically matched con...

journal_title：Neuroreport

authors： Till C,Deotto A,Tipu V,Sled JG,Bethune A,Narayanan S,Arnold DL,Banwell BL

更新日期：2011-12-21 00:00:00

abstract：:In addition to the study of pathological conditions, magnetic resonance spectroscopy can provide useful information about brain-behavior relationships in normal subjects. Recently, there have been reports of correlations between N-acetylaspartate (NAA) values and cognitive functions in normal adults. We tested the pos...

journal_title：Neuroreport

authors： Giménez M,Junqué C,Narberhaus A,Caldú X,Segarra D,Vendrell P,Bargalló N,Mercader JM

更新日期：2004-03-22 00:00:00

abstract：:Neuregulins (NRG), the only trophic factors known to support Schwann cell survival, have a potential for use in treatment of patients with chronic neuropathies. Expression of one NRG isoform, NRG-beta1, was increased in axons in the early phase of axonal degeneration in nerve biopsy specimens from patients with neurop...

journal_title：Neuroreport

authors： Oka N,Kawasaki T,Matsui M,Tachibana H,Sugita M,Akiguchi I

更新日期：2000-11-27 00:00:00

abstract：:Exosomes derived from Schwann cells have been known to have a variety of functions in the development and repair of the peripheral nervous system, and cyclic AMP (cAMP) is a key inducer of Schwann cell differentiation. In the present study, we aimed to study the effect of exosomes derived from differentiated Schwann c...

journal_title：Neuroreport

authors： Sohn EJ,Park HT,Shin YK

更新日期：2020-05-07 00:00:00

abstract：:The present study reveals the presence of a distinct group of cells, resembling reticular thalamic neurones, in the internal capsule during fetal development. This cell population rapidly decreases in size during early infancy and few cells are apparent in the 1-year-old infant. Internal capsule cells are well differe...

journal_title：Neuroreport

authors： Letinić K,Kostović I

更新日期：1996-09-02 00:00:00

abstract：:Neonatal peripheral inflammation has been shown to alter the neural circuitry of the spinal cord in adult rats. However, the temporal and spatial changes in the distribution of primary afferent terminals immediately following a neonatal inflammatory stimulus remains unclear. In the present study we found that intrapla...

journal_title：Neuroreport

authors： Ling QD,Chien CC,Wen YR,Fu WM,Sun WZ

更新日期：2003-10-27 00:00:00

abstract：:The localization of PKC gamma mRNA expression during the maturation of rat cerebellum has been studied by in situ hybridization. We found a transient expression over the granule cell layer and persistent high expression in the Purkinje cells during postnatal development. Expression in granule cells appeared as early a...

journal_title：Neuroreport

authors： Herms J,Zurmöhle U,Schlingensiepen KH,Brysch W

更新日期：1993-07-01 00:00:00

abstract：:Cortical auditory categorization was assessed in 2-month-old infants at genetic risk for dyslexia and controls. Manipulated /bAk/ and /dAk/ speech stimuli were used as frequently presented standards. The neuroelectric brain responses of the control infants were highly sensitive to the phoneme boundary that separated t...

journal_title：Neuroreport

authors： van Leeuwen T,Been P,van Herten M,Zwarts F,Maassen B,van der Leij A

更新日期：2007-06-11 00:00:00

abstract：:Skin sensory nerve nocifensor functions were investigated non-invasively in rats by measuring neurogenic inflammation and blister healing-rate after unilateral hindlimb denervation. Axon reflexes were evoked by transdermal iontophoresis of acetylcholine (ACh) or noxious electrical stimulation (TNS). Sodium nitroprussi...

journal_title：Neuroreport

authors： Carr RW,Delaney CA,Westerman RA,Roberts RG

更新日期：1993-05-01 00:00:00

abstract：:In an attempt to determine whether small focal malformations of the neocortex can be visualized in vivo, focal microgyria were induced in the neocortex of otherwise normal rats by freezing injury to the developing cortical plate, and in adulthood the malformation was visualized using MRI. Induced microgyria of varying...

journal_title：Neuroreport

authors： Rosen GD,Burstein D

更新日期：1997-12-22 00:00:00

abstract：:Olfactory cues can elicit intense emotional responses. This study used fMRI in male common marmoset monkeys to identify brain areas associated with sexual arousal in response to odors of ovulating female monkeys. Under light anesthesia, monkeys were secured in a specially designed restrainer and positioned in a 9.4 T ...

journal_title：Neuroreport

authors： Ferris CF,Snowdon CT,King JA,Duong TQ,Ziegler TE,Ugurbil K,Ludwig R,Schultz-Darken NJ,Wu Z,Olson DP,Sullivan JM Jr,Tannenbaum PL,Vaughan JT

更新日期：2001-07-20 00:00:00

abstract：:Substantial evidence suggests a negative association between cigarette smoking and the incidence and severity of ulcerative colitis, a common human inflammatory bowel disease. Nicotine has been implicated in this association. The detection of nicotinic acetylcholine receptors in colonic epithelium, the primary tissue ...

journal_title：Neuroreport

authors： Orr-Urtreger A,Kedmi M,Rosner S,Karmeli F,Rachmilewitz D

更新日期：2005-07-13 00:00:00

abstract：:Humans use vestibular head-in-space information when redirecting gaze towards remembered target location in space. This study shows that neck input is also involved. Normal subjects performed saccades towards remembered locations in space of a previously seen target following passive horizontal rotations of the head o...

journal_title：Neuroreport

authors： Mergner T,Nasios G,Anastasopoulos D

更新日期：1998-05-11 00:00:00

abstract：:Freshly dissected and dissociated subventricular zone cells from adult male mice were transplanted into the right cerebral cortex of adult female mice. Host mice were perfused 3 or 7 weeks later. To detect donor male cells, paraffin sections (10 microm) were hybridized in situ with a Y-chromosome-specific probe. Some ...

journal_title：Neuroreport

authors： Harvey AR,Symons NA,Pollett MA,Brooker GJ,Bartlett PF

更新日期：1997-12-22 00:00:00

abstract：:Anti-leucine-rich glioma inactivated 1 (anti-LGI1) encephalitis is one of the most frequently encountered forms of autoimmune encephalitis. Many patients with anti-LGI1 encephalitis develop permanent hippocampal neuron loss and chronic neuropsychiatric symptoms, suggesting that LGI antibodies (Ab) might have a neuroto...

journal_title：Neuroreport

authors： Ayşit-Altuncu N,Ulusoy C,Öztürk G,Tüzün E

更新日期：2018-08-01 00:00:00

abstract：:We screened proteins for interaction with presenilin (PS) 1, and cloned the full-length cDNA of human delta-catenin, which encoded 1225 amino acids. Yeast two-hybrid assay, GST binding assay and immunoprecipitation demonstrated that delta-catenin interacted with a hydrophilic loop region in the endoproteolytic C-termi...

journal_title：Neuroreport

authors： Tanahashi H,Tabira T

更新日期：1999-02-25 00:00:00