White matter integrity and math performance in pediatric multiple sclerosis: a diffusion tensor imaging study.

abstract：:MicroRNAs (miRNAs) play important roles in drug tolerance and regulating pain. The purpose of the present study is to explore the regulatory mechanism of miR-124-3p on dezocine tolerance against pain in a rat model. The expression of miR-124-3p and TRAF6 in spinal cord of rats was detected by quantitative reverse-tran...

journal_title：Neuroreport

authors： Huo Y,Zhang K,Zhang T,Han Y,Hu Z

更新日期：2021-01-06 00:00:00

abstract：:The reduced steroids 3 alpha-hydroxy-5 alpha-pregnan-20-one (allopregnanolone) and 3 alpha,21-di-hydroxy-5 alpha-pregnan-20-one (allotetrahydroDOC) are potent ligands of GABAA receptors. This study examined the possible modulatory effect of these metabolites on GABA inhibition of somatostatin release in cultured hypot...

journal_title：Neuroreport

authors： Tapia-Arancibia L,André M,Belmar J,Arancibia S

更新日期：1995-10-02 00:00:00

abstract：:In isolated neurons of Helix pomatia, a two-microelectrode voltage clamp technique was used to study the effect of Fe3+ on voltage-gated potassium currents: a low-threshold fast-inactivating current (I(A)) and a high threshold slow-inactivating current with calcium-dependent (I(C)) and calcium-independent (I(DR)) comp...

journal_title：Neuroreport

authors： Bukanova JV,Solntseva EI,Skrebitsky VG

更新日期：2007-08-27 00:00:00

abstract：:The organization of the main olfactory bulb of an insectivore, the laboratory shrew (Suncus murinus), was studied morphologically. We found particular small spherical regions, nidi, at the border between the glomerular and external plexiform layer (EPL), which were intensely GAD positive, 30-60 microm in diameter, and...

journal_title：Neuroreport

authors： Kosaka K,Kosaka T

更新日期：1999-02-05 00:00:00

abstract：:Prefrontal delay-period activity represents a neural mechanism for the active maintenance of information and needs to be controlled by some signal to appropriately operate working memory. To examine whether reward-delivery acts as this signal, the effects of delay-period activity in response to unexpected reward-deliv...

journal_title：Neuroreport

authors： Ichihara-Takeda S,Takeda K,Funahashi S

更新日期：2010-03-31 00:00:00

abstract：:Kisspeptin is distributed not only in brain areas for regulating reproduction but also in nuclei involved in feeding control. Whether kisspeptin alters food intake is unknown in mice. We examined how kisspeptin-10 influences feeding after intracerebroventricular injection in mice using automated monitoring. Kisspeptin...

journal_title：Neuroreport

authors： Stengel A,Wang L,Goebel-Stengel M,Taché Y

更新日期：2011-03-30 00:00:00

abstract：:We investigated the influence of gravity on the maturation of electrical properties of lumbar motoneurons and the development of their inputs from ventral descending pathways, which are important for the control of posture and locomotion. Using electrophysiological approaches in the in vitro brain stem-spinal cord pre...

journal_title：Neuroreport

authors： Brocard F,Clarac F,Vinay L

更新日期：2003-09-15 00:00:00

abstract：:The study aimed to investigate the time-course of electromagnetic field (EMF)-induced effects on human cognitive and behavioral performance and on tympanic temperature. Subjects were randomly assigned to two groups, exposed to a 902.40 MHz EMF before the testing session, or to the same signal during the data collectin...

journal_title：Neuroreport

authors： Curcio G,Ferrara M,De Gennaro L,Cristiani R,D'Inzeo G,Bertini M

更新日期：2004-01-19 00:00:00

abstract：:Resident microglial cells contribute to activation and expansion of T cells under inflammatory conditions within the CNS. However, there is no evidence how interactions between microglia and T cells affect CNS inflammation. We evaluated the effect of glial cell-derived dendritic cells (GC-DC) in expanding and eliminat...

journal_title：Neuroreport

authors： Xu LY,Yang JS,Xiao BG

更新日期：2002-01-21 00:00:00

abstract：:Regulation of CNS distribution of the human immunodeficiency virus (HIV) protease inhibitor saquinavir may involve ATP-dependent membrane-bound efflux transport proteins that are expressed in several brain cellular compartments. We recently characterized molecular and functional expression of one such transporter, mul...

journal_title：Neuroreport

authors： Dallas S,Ronaldson PT,Bendayan M,Bendayan R

更新日期：2004-05-19 00:00:00

abstract：:The rat synaptosomal membrane antigen D3, which has been studied for more than 20 years since its first demonstration as a brain-specific protein, was shown to bind monoclonal antibodies to SNAP-25, a presynaptic plasma membrane-associated protein. In addition to SNAP-25, anti-D3 antiserum also precipitated two polype...

journal_title：Neuroreport

authors： Jørgensen OS

更新日期：1995-12-29 00:00:00

abstract：:The effects of a pharmacological blockade of the periaqueductal grey of the midbrain (PAG) on the elicitability of vocal fold movements from the facial motor cortex on the one hand and the anterior cingulate cortex and dorsomedial hypothalamus on the other were studied in the squirrel monkey. PAG blockade abolished vo...

journal_title：Neuroreport

authors： Jürgens U,Zwirner P

更新日期：1996-11-25 00:00:00

abstract：:In this study, we determined whether the visuospatial attention network of frontal, parietal, and occipital cortex can be parsed into two different subsets of active regions associated with transient and sustained processes within the same cue-to-target delay period of an endogenously cued visuospatial attention task....

journal_title：Neuroreport

authors： Luks TL,Sun FT,Dale CL,Miller WL,Simpson GV

更新日期：2008-01-22 00:00:00

abstract：:Distracted driving remains a leading factor in fatal motor vehicle crashes, particularly in young drivers. Due to ongoing neuromaturation, attention capabilities are changing and improving throughout young adulthood. Here, we sought to bridge neuroscience with driving simulation by evaluating the effects of driving on...

journal_title：Neuroreport

authors： Banz BC,Wu J,Camenga DR,Mayes LC,Crowley MJ,Vaca FE

更新日期：2020-05-22 00:00:00

abstract：:Repetitive transcranial magnetic stimulation (rTMS) has been tried therapeutically in major depression. In order to investigate the therapeutic efficacy of rTMS in psychotic patients, 12 participants (four women, eight men) with schizophrenia according to DSM-IV criteria, aged 25 to 63 years (mean (+/-s.d) 40.4+/-11.0...

journal_title：Neuroreport

authors： Rollnik JD,Huber TJ,Mogk H,Siggelkow S,Kropp S,Dengler R,Emrich HM,Schneider U

更新日期：2000-12-18 00:00:00

abstract：:In the present study the effects of intracerebroventricular (ICV) administration of baclofen (0.1-5.0 nmol) was investigated on food intake in non-fasted rats. Baclofen (1.0, 2.5 and 5.0 nmol) increased food consumption in a dose-related manner during the first 15-30 min after administration. The effects of baclofen (...

journal_title：Neuroreport

authors： Ebenezer IS

更新日期：1990-09-01 00:00:00

abstract：:This study is to explore the involvement of muscarinic acetylcholine receptors/protein kinase C cascade and the mitogen-activated protein kinase pathway in the effect of huperzine A on the secretory amyloid precursor protein-alpha. Upregulation of secretory amyloid precursor protein-alpha by huperzine A was attenuated...

journal_title：Neuroreport

authors： Yan H,Zhang HY,Tang XC

更新日期：2007-05-07 00:00:00

abstract：:We produced NB3C4, a novel monoclonal antibody specific for oligodendrocytes, using human neuroblastoma IMR-32 cells. NB3C4 specifically recognized oligodendrocytes in the CNS, although it bound to neuroblastoma IMR-32 cells and oligodendrocytes in vitro. Double immunofluorescence staining of rat brain using NB3C4 and...

journal_title：Neuroreport

authors： Yoshimura K,Kametani F,Shimoda Y,Fujimaki K,Sakurai Y,Kitamura K,Asou H,Nomura M

更新日期：2001-02-12 00:00:00

abstract：:Decoding verbal and nonverbal emotional expressions is an important part of speech communication. Although various studies have tried to specify the brain regions that underlie different emotions conveyed in speech, few studies have aimed to specify the time course of emotional speech decoding. We used event-related p...

journal_title：Neuroreport

authors： Paulmann S,Kotz SA

更新日期：2008-01-22 00:00:00

abstract：:In contrast to mammals, the brains of teleost fish exhibit an enormous regenerative capacity following injury. Here, we have examined the potential role of vimentin in this wound healing. Fifteen days after application of a mechanical lesion to the corpus cerebelli in the teleost fish Apteronotus leptoryhnchus, the ar...

journal_title：Neuroreport

authors： Clint SC,Zupanc GK

更新日期：2002-03-04 00:00:00

abstract：:Rats with bilateral electrolytic lesions of the perirhinal cortex and sham operated control rats were tested in a spatially guided, delayed non match to sample task. Although perirhinal lesioned animals showed no deficit in acquisition of the task, a performance deficit was observed across longer delay intervals. Thes...

journal_title：Neuroreport

authors： Wiig KA,Bilkey DK

更新日期：1994-06-27 00:00:00

abstract：:Histamine-related drugs are commonly used in the treatment of vertigo and related vestibular disorders. Their site and mechanism of action, however, are still poorly understood. To increase our knowledge of the histaminergic system in the vestibular organs, we have investigated the expression of H1 and H3 histamine re...

journal_title：Neuroreport

authors： Botta L,Tritto S,Perin P,Laforenza U,Gastaldi G,Zampini V,Zucca G,Valli S,Masetto S,Valli P

更新日期：2008-03-05 00:00:00

abstract：:This study aimed to investigate effects of observing the own body being touched on the functional topography of the somatosensory homunculus. We used neuromagnetic source imaging to map the topography in primary somatosensory cortex (SI) while manipulating the visibility of a touched hand. Participants were either abl...

journal_title：Neuroreport

authors： Schaefer M,Heinze HJ,Rotte M

更新日期：2008-06-11 00:00:00

abstract：:The role of spinal NMDA receptors in mechanical nociceptive processing was assessed in sheep. Intrathecal NMDA (2 nmol-1 micromol) produced a significant reduction in mechanical withdrawal thresholds. This effect was attenuated by pretreatment with the NMDA receptor antagonist MK801 (100 nmol), the cyclooxygenase-2 (C...

journal_title：Neuroreport

authors： Dolan S,Nolan AM

更新日期：1999-02-25 00:00:00

abstract：:Methamphetamine (METH)-induced dopaminergic neurotoxicity is associated with hyperthermia. We investigated the effect of several neuronal nitric oxide synthase (nNOS) inhibitors on METH-induced hyperthermia and striatal dopaminergic neurotoxicity. Administration of METH (5 mg/kg; q. 3 h x 3) to Swiss Webster mice prod...

journal_title：Neuroreport

authors： Itzhak Y,Martin JL,Ail SF

更新日期：2000-09-11 00:00:00

abstract：:Rats with an experimental painful peripheral neuropathy (the chronic injury (CCI) model) display heatevoked hyperalgesia. There is now considerable evidence that nitric oxide (NO) and nitric oxide synthase are involved in the development of hyperalgesia in acute inflammatory pain states. The mechanisms responsible for...

journal_title：Neuroreport

authors： Tal M

更新日期：1996-05-31 00:00:00

abstract：:The effects of high frequency repetitive transcranial magnetic stimulation on sensory perception and the pain tolerance thresholds were investigated applying both motor cortex stimulation and medial frontal cortex stimulation in normal study participants. Both the sensory perception and pain tolerance thresholds were ...

journal_title：Neuroreport

authors： Yoo WK,Kim YH,Doh WS,Lee JH,Jung KI,Park DS,Park ES

更新日期：2006-02-06 00:00:00

abstract：:The activation of GABAB receptors hyperpolarizes 5-HT neurons and reduces cell firing. In situ hybridization showed the presence of the GABAB-RI receptor transcript in virtually all 5-HT neurons of the dorsal and median raphe nuclei (DR and MnR, respectively) whereas the GAD transcript was present mainly outside these...

journal_title：Neuroreport

authors： Abellán MT,Adell A,Honrubia MA,Mengod G,Artigas F

更新日期：2000-04-07 00:00:00

abstract：:Using functional magnetic resonance imaging during word generation and spatial judgement (Landmark task), we investigated how hemispheric specializations for language and spatial processing interact in healthy individuals. We found individuals with atypical, right-hemispheric dominance for language to have more bilate...

journal_title：Neuroreport

authors： Jansen A,Flöel A,Menke R,Kanowski M,Knecht S

更新日期：2005-06-21 00:00:00

abstract：:Sirtuin 2 (SIRT2) is a member of the sirtuin family. Previous studies have suggested that SIRT2 mediates the cell death in models of Parkinson's disease and Huntington's disease. However, the role of SIRT2 in oxidative stress-induced cell death has remained unclear. In this study, we investigated the roles of SIRT2 in...

journal_title：Neuroreport

authors： Nie H,Hong Y,Lu X,Zhang J,Chen H,Li Y,Ma Y,Ying W

更新日期：2014-08-06 00:00:00