Abstract:
:Prefrontal delay-period activity represents a neural mechanism for the active maintenance of information and needs to be controlled by some signal to appropriately operate working memory. To examine whether reward-delivery acts as this signal, the effects of delay-period activity in response to unexpected reward-delivery were examined by analyzing single-neuron activity recorded in the primate dorsolateral prefrontal cortex. Among neurons that showed delay-period activity, 34% showed inhibition of this activity in response to unexpected reward-delivery. The delay-period activity of these neurons was affected by the expectation of reward-delivery. The strength of the reward signal in controlling the delay-period activity is related to the strength of the effect of reward information on the delay-period activity. These results indicate that reward-delivery acts as a signal to control delay-period activity.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Ichihara-Takeda S,Takeda K,Funahashi Sdoi
10.1097/WNR.0b013e32833776a3subject
Has Abstractpub_date
2010-03-31 00:00:00pages
367-70issue
5eissn
0959-4965issn
1473-558Xjournal_volume
21pub_type
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