Nogo-66 receptor at the gap junctions between pituicytes of the rat.

Abstract:

:Nogo-66 receptor was first identified in neurons. Recently, it was demonstrated in glial cells as well. Our previous study on the expression of Nogo-66 receptor in the cerebellum of the rat surprisingly found its location at the glial gap junctions. Here, we present our study on Nogo-66 receptor in the rat posterior pituitary, which is densely packed with pituicytes, a special type of astrocyte, and is known to be rich in gap junctions. We were able to demonstrate with immunohistochemistry and immuno-electron microscopy abundant Nogo-66 receptor immunoreactive gap junctions between pituicytes. This study, together with our prior one, strongly suggests that the Nogo-66 receptor may play a role in regulating the function of the gap junctions.

journal_name

Neuroreport

journal_title

Neuroreport

authors

Wang YZ,Liu YY,Liu JP,You SW,Ju G

doi

10.1097/00001756-200604240-00010

subject

Has Abstract

pub_date

2006-04-24 00:00:00

pages

605-9

issue

6

eissn

0959-4965

issn

1473-558X

pii

00001756-200604240-00010

journal_volume

17

pub_type

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