Abstract:
:Nogo-66 receptor was first identified in neurons. Recently, it was demonstrated in glial cells as well. Our previous study on the expression of Nogo-66 receptor in the cerebellum of the rat surprisingly found its location at the glial gap junctions. Here, we present our study on Nogo-66 receptor in the rat posterior pituitary, which is densely packed with pituicytes, a special type of astrocyte, and is known to be rich in gap junctions. We were able to demonstrate with immunohistochemistry and immuno-electron microscopy abundant Nogo-66 receptor immunoreactive gap junctions between pituicytes. This study, together with our prior one, strongly suggests that the Nogo-66 receptor may play a role in regulating the function of the gap junctions.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Wang YZ,Liu YY,Liu JP,You SW,Ju Gdoi
10.1097/00001756-200604240-00010subject
Has Abstractpub_date
2006-04-24 00:00:00pages
605-9issue
6eissn
0959-4965issn
1473-558Xpii
00001756-200604240-00010journal_volume
17pub_type
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