NCAM-180 knockout mice display increased lateral ventricle size and reduced prepulse inhibition of startle.

abstract：:We investigated whether short-term saccadic adaptation modifies hand pointing. Subjects were presented with double-step targets, the second target jump occurring during the saccade to the first one and bringing the target back to 66% of the first target eccentricity, in order to reduce the gain of their gaze saccades....

journal_title：Neuroreport

authors： de Graaf JB,Pélisson D,Prablanc C,Goffart L

更新日期：1995-09-11 00:00:00

abstract：:We have developed in new-born mice a ventral tilted-horizontal slice preparation for pontine stimulation and recording of spontaneous respiratory-like rhythmic trains of glutamatergic excitatory postsynaptic potentials (EPSPs) in medullary neurons. Electrical stimulations (10-50 Hz for 100-500 ms) of the caudal pontin...

journal_title：Neuroreport

authors： Borday V,Kato F,Champagnat J

更新日期：1997-12-01 00:00:00

abstract：:Insulin-like growth factor-1 (IGF-1) and erythropoietin (EPO) are induced in brain cells after brain ischemia and show synergistic neuroprotective effects. In LN215 astrocytoma cells, IGF-1 induced the activation of hypoxia-inducible factor-1, leading to increases in EPO mRNA levels and the secretion of EPO. Interesti...

journal_title：Neuroreport

authors： Kim I,Kim CH,Yim YS,Ahn YS

更新日期：2008-11-19 00:00:00

abstract：:Poly(ADP-ribose) polymerase-1 consumes NAD to catalyze poly(ADP-ribosyl)ation of target proteins, which modulates various biological functions. However, excessive poly(ADP-ribose) polymerase-1 activation mediates oxidative cell death. Our recent studies have indicated that NAD can enter into astrocytes to prevent poly...

journal_title：Neuroreport

authors： Zhu K,Swanson RA,Ying W

更新日期：2005-08-01 00:00:00

abstract：:Nicotine injected in the supraoptic nucleus facilitates vasopressin release from the neurohypophysis. Nicotinic acetylcholine receptors have been found not only on vasopressin-producing cell bodies but also on presynaptic nerve terminals in the nucleus. Vasopressin cells receive excitatory synaptic inputs from noradre...

journal_title：Neuroreport

authors： Liu X,Onaka T,Yagi K

更新日期：2001-03-05 00:00:00

abstract：:Apolipoprotein E (apoE) and the beta-amyloid peptide are both found in the senile plaques associated with Alzheimer's disease. Several studies have recently determined that apoE can prevent beta-amyloid fibril (Abetaf) formation in vitro. In vivo, apoE is normally associated with a lipid source. We show that both reco...

journal_title：Neuroreport

authors： Beffert U,Poirier J

更新日期：1998-10-05 00:00:00

abstract：:With increasing age, the electrophysiological event-related potentials P3a/P3b tend to get a more frontal maximum. The cognitive significance of this so-called frontal shift is not known, but hypotheses have focused on changes in the integrity of the frontal lobes. The aim of the present study was to test how the thic...

journal_title：Neuroreport

authors： Fjell AM,Walhovd KB,Reinvang I

更新日期：2005-09-08 00:00:00

abstract：:Plasticity in the central nervous system may play an important role in clinical pain. The present study shows that long-term potentiation (LTP) may be induced in single wide dynamic range (WDR) neurons in the dorsal horn after high-frequency stimulation of the sciatic nerve in intact urethane anaesthetized rats. Extra...

journal_title：Neuroreport

authors： Svendsen F,Tjølsen A,Hole K

更新日期：1997-11-10 00:00:00

abstract：:The effect of thyroid hormone (TH) deficiency on the expression of neurofilament (NF) proteins and their intracellular distribution has been examined in primary cultures of neurons from embryonic rat cerebra. Northern blot analysis showed that in TH-deficient (THdef) neurons, the expression of all three NF mRNAs (NF-L...

journal_title：Neuroreport

authors： Rahaman SO,Ghosh S,Mandal SK,Sarkar PK

更新日期：2000-08-21 00:00:00

abstract：:The present study used the N400, an electrophysiological correlate of semantic processing, to investigate 19- and 24-month-old children's ability to integrate the meaning of words in a sentential context. Children listened passively to semantically appropriate sentences and to sentences in which the object noun violat...

journal_title：Neuroreport

authors： Friedrich M,Friederici AD

更新日期：2005-11-07 00:00:00

abstract：:Scanning laser-Doppler flowmetry (SLDF) combines laser-Doppler flowmetry and laser scanning to provide images of cerebral blood flow (CBF) with high spatial and temporal resolution. We investigated the contribution of single vascular elements to the local increase of CBF accompanying increased neuronal activity in hal...

journal_title：Neuroreport

authors： Akgören N,Lauritzen M

更新日期：1999-11-08 00:00:00

abstract：:We demonstrate the use of magnetic resonance imaging (MRI) for detection of neurotransmitter stimulation using the dopamine transporter ligands amphetamine and CFT (2beta-carbomethoxy-3beta-(4-fluorophenyl)tropane) as pharmacological challenges. We demonstrate that the unilateral loss of a hemodynamic response to eith...

journal_title：Neuroreport

authors： Chen YI,Brownell AL,Galpern W,Isacson O,Bogdanov M,Beal MF,Livni E,Rosen BR,Jenkins BG

更新日期：1999-09-29 00:00:00

abstract：:We measured regional cerebral blood flow using positron emission tomography in seven normal volunteers during discrimination tasks for visual patterns. For the 'attention to right or left' tasks, the subjects were instructed to press a key when sample and test stimuli presented in the right or left visual fields, resp...

journal_title：Neuroreport

authors： Kawashima R,Satoh K,Goto R,Inoue K,Itoh M,Fukuda H

更新日期：1998-05-11 00:00:00

abstract：:Salidroside (SDS), a phenylpropanoid glycoside isolated from Rhodiola rosea L., has been reported to be neuroprotective in vitro, which raises the possibility of using SDS as a neuroprotective agent after nerve injuries. In the present study, the possibly beneficial effect of SDS on promoting nerve regeneration after ...

journal_title：Neuroreport

authors： Sheng QS,Wang ZJ,Zhang J,Zhang YG

更新日期：2013-03-27 00:00:00

abstract：:We used whole-cell recording to identify, for the first time, GABAergic tonic current in subpopulations of substantia gelatinosa neurons in mouse spinal cord slices. Application of the gamma-aminobutyric acid type A receptor antagonist bicuculline revealed tonic currents in 49 of 73 substantia gelatinosa neurons. Thes...

journal_title：Neuroreport

authors： Takahashi A,Mashimo T,Uchida I

更新日期：2006-08-21 00:00:00

abstract：:The present study was based on earlier findings that the observation of a coherently moving long bar induced gamma-band activity in humans. The power in the EEG-gamma-band was reduced during the presentation of two incoherently moving short bars. The present study demonstrates the replicability of this cortical activi...

journal_title：Neuroreport

authors： Müller MM,Junghöfer M,Elbert T,Rochstroh B

更新日期：1997-07-28 00:00:00

abstract：:Functional brain imaging techniques hold many promises as the methods of choice for identifying areas involved in the execution of language functions. The success of any of these techniques in fulfilling this goal depends upon their ability to produce maps of activated areas that overlap with those obtained through st...

journal_title：Neuroreport

authors： Simos PG,Breier JI,Maggio WW,Gormley WB,Zouridakis G,Willmore LJ,Wheless JW,Constantinou JE,Papanicolaou AC

更新日期：1999-01-18 00:00:00

abstract：:Amygdala and insula hyper-reactivity to threat is implicated in social anxiety disorder (SAD) yet inconsistencies in activation have been reported. One source of variance are individual differences in 5-HTTLPR genotype where the short (S), relative to long (L) allele, corresponds with greater amygdala activation. Howe...

journal_title：Neuroreport

authors： Klumpp H,Fitzgerald DA,Cook E,Shankman SA,Angstadt M,Phan KL

更新日期：2014-08-20 00:00:00

abstract：:With the purpose of mapping representations of the finger and proximal arm in the human primary motor cortex (MI), we measured regional cerebral blood flow (rCBF) in eight right-handed normal volunteers during self-paced finger and proximal arm movements. Each movement activated two different fields in MI, one located...

journal_title：Neuroreport

authors： Kawashima R,Itoh H,Ono S,Satoh K,Furumoto S,Gotoh R,Koyama M,Yoshioka S,Takahashi T,Yanagisawa T

更新日期：1995-01-26 00:00:00

abstract：:Integrating information across the senses can enhance our ability to detect and classify stimuli in the environment. For example, auditory speech perception is substantially improved when the speaker's face is visible. In an fMRI study designed to investigate the neural mechanisms underlying these crossmodal behaviour...

journal_title：Neuroreport

authors： Calvert GA,Brammer MJ,Bullmore ET,Campbell R,Iversen SD,David AS

更新日期：1999-08-20 00:00:00

abstract：:Opioid-receptor-like I (ORLI) receptors, ORLI mRNA and nociceptin are particularly abundant in the limbic system and in central monoaminergic areas, brain regions involved in mood regulation and response to antidepressants. To analyse whether ORLI receptors adaptations occur during the first 3 weeks of an antidepressa...

journal_title：Neuroreport

authors： Vilpoux C,Naudon L,Costentin J,Leroux-Nicollet I

更新日期：2002-01-21 00:00:00

abstract：:A polymorphism of the apolipoprotein E gene, in particular the epsilon 4 allele (ApoE4), has been associated with impaired neuronal phospholipid metabolism and synapse reorganization and has been implicated in several neurodegenerative disorders. Since selective neuronal cell lose and aberrant axonal reorganization re...

journal_title：Neuroreport

authors： Blümcke I,Brockhaus A,Scheiwe C,Rollbrocker B,Wolf HK,Elger CE,Wiestler OD

更新日期：1997-03-24 00:00:00

abstract：:Slices of hippocampus were incubated with Arg-Gly-Asp (RGD) peptides known to block members of the integrin class of matrix receptors. Though the peptides caused no detectable difference in the amount of long-term potentiation (LTP) expressed in the CA1 field 1-2 min after induction with high frequency stimulation, th...

journal_title：Neuroreport

authors： Xiao P,Bahr BA,Staubli U,Vanderklish PW,Lynch G

更新日期：1991-08-01 00:00:00

abstract：:CEP-1347 inhibits the signalling pathway of c-jun-N-terminal kinase, and is neuroprotective in vivo and in vitro. Embryonic chick dorsal root ganglion neurones are dependent on NGF for survival and neurite outgrowth; NGF withdrawal results in apoptotic cell death. We examined the neuroprotective and neurite outgrowth ...

journal_title：Neuroreport

authors： Bilsland JG,Harper SJ

更新日期：2003-05-23 00:00:00

abstract：:Semi-quantitative single cell RT-PCR techniques were used to determine the expression of mRNAs related to GABAergic and cholinergic neurotransmission in neurons of the rat globus pallidus and adjacent basal forebrain region. Neurons of the globus pallidus expressed relatively high levels of GAD67 and GABA vesicular tr...

journal_title：Neuroreport

authors： Tkatch T,Baranauskas G,Surmeier DJ

更新日期：1998-06-22 00:00:00

abstract：:Prepulse inhibition (PPI) and reactivity of the acoustic startle response are widely used biobehavioral markers in psychopathology research. Previous studies have demonstrated that PPI and startle reactivity exhibit substantial within-site stability; however, between-site stability has not been established. In two sep...

journal_title：Neuroreport

authors： Cadenhead KS,Addington J,Cannon TD,Cornblatt BA,de la Fuente-Sandoval C,Mathalon DH,Perkins DO,Seidman LJ,Tsuang M,Walker EF,Woods SW,Bachman P,Belger A,Carrión RE,Donkers FC,Duncan E,Johannesen J,León-Ortiz P,Light G

更新日期：2013-08-07 00:00:00

abstract：:The functional organization of intrinsic connections in the cat motor cortex was examined by combining intracortical microstimulation with neuroanatomical tracers. After single injections of a dye into a cortical site from which wrist flexion was evoked, clusters of retrogradely labeled somata and of anterogradely lab...

journal_title：Neuroreport

authors： Keller A

更新日期：1993-05-01 00:00:00

abstract：:We examined the cortical areas showing increased activation related to axis orientation discrimination in hand movement and perception by positron emission tomography (PET) in right-handed normal human subjects while they performed a hand orientation (HO) task and an orientation discrimination (OD) task. In the OD tas...

journal_title：Neuroreport

authors： Taira M,Kawashima R,Inoue K,Fukuda H

更新日期：1998-01-26 00:00:00

abstract：:The brain constructs multiple representations of near and far space but it is unclear which spatial mechanism guides reaching across eye movements in near space. Retinocentric reaching representations are known to exist in parietal cortex, but must be updated during eye movements, in order to remain accurate. In contr...

journal_title：Neuroreport

authors： Medendorp WP,Crawford JD

更新日期：2002-04-16 00:00:00

abstract：:Event-related brain potentials were examined in 6 to 8-year-old children with primary language disorder before and after a 5-week narrative-based language intervention. Participants listened to sentences ending with semantically congruous or incongruous words. By comparison with typical controls, the children with pri...

journal_title：Neuroreport

authors： Popescu M,Fey ME,Lewine JD,Finestack LH,Popescu EA

更新日期：2009-08-05 00:00:00