Abstract:
:Effects of adrenalectomy on the 5-HT1A receptor agonist 8-hydroxy-2-di-n-(propylamino)tetralin (8-OH-DPAT)- and 2-deoxy-D-glucose (2-DG)-induced hyperphagia were investigated in rats. Prior adrenalectomy completely inhibited 2-DG-induced hyperphagia, although it did not affect increases in food intake elicited by 8-OH-DPAT. These results suggest that 8-OH-DPAT-induced hyperphagia is independent of the adrenal hormone, corticosterone while 2-DG-induced hyperphagia is closely related to corticosterone.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Yamada J,Sugimoto Y,Yoshikawa Tdoi
10.1097/00001756-199806010-00030subject
Has Abstractpub_date
1998-06-01 00:00:00pages
1831-3issue
8eissn
0959-4965issn
1473-558Xjournal_volume
9pub_type
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