Abstract:
:The whole cell configuration of the patch clamp technique was used to study the biophysical and pharmacological properties of voltage activated Ca2+ channel currents on hippocampal neurones cultured in the presence or absence of foetal calf serum. In the presence of serum cells were intensively immunostained with neurofilament (NF) antibodies. In the absence of serum, cells were non-immunoreactive; they were identified as neurones by their ability to generate action potentials. NF negative cells still expressed both high (HVA) and low (LVA) voltage activated Ca2+ channels. However, in comparison to NF positive neurones, HVA Ca2+ currents present in NF negative neurones had a faster inactivation kinetics.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Bertollini L,Cattaneo A,Cherubini Edoi
10.1097/00001756-199504190-00008subject
Has Abstractpub_date
1995-04-19 00:00:00pages
857-60issue
6eissn
0959-4965issn
1473-558Xjournal_volume
6pub_type
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