Within- and between-channel gap detection in the human auditory cortex.

abstract：:In order to accomplish desired movements, the nervous system must specify the movement dynamics: it must provide a signal that compensates for the mechanical constraints encountered during movement. Here we tested whether the population activity of Purkinje cells in the cerebellum specifies the dynamics for pursuit ey...

journal_title：Neuroreport

authors： Krauzlis RJ

更新日期：2000-04-07 00:00:00

abstract：:GABAA receptors mediate the inhibition of somatostatin release in hypothalamic neurones. To study the possible effect of GABA on somatostatin biosynthesis, somatostatin and preprosomatostatin mRNA levels were evaluated after exposure of hypothalamic neurones to muscimol or bicuculline. Muscimol (50 microM) decreased p...

journal_title：Neuroreport

authors： Rage F,Jalaguier S,Rougeot C,Tapia-Arancibia L

更新日期：1993-03-01 00:00:00

abstract：:Hemispheric (re-)organization of episodic memory functions after temporal lobe damage (TLD) was investigated by the intracarotid amobarbital procedure in patients suffering temporal lobe epilepsy. Memory of the speech-dominant left hemisphere was intact after right-sided TLD independent of the age at manifestation. In...

journal_title：Neuroreport

authors： Jokeit H,Ebner A,Holthausen H,Markowitsch HJ,Tuxhorn I

更新日期：1996-07-08 00:00:00

abstract：:Episodic memory for simple commands is better following enacted than verbal encoding. This has been proposed to be due to the possibility to base retrieval on motor information. Here we used PET to test the hypothesis that motor brain areas show increased retrieval-related activity following enacted compared to verbal...

journal_title：Neuroreport

authors： Nilsson LG,Nyberg L,Klingberg T,Aberg C,Persson J,Roland PE

更新日期：2000-07-14 00:00:00

abstract：:The time-dependent effect of transcranial direct current stimulation (tDCS) on working memory was investigated by applying anodal stimulation over the left prefrontal cortex. This single-blind, sham-controlled crossover study recruited 15 healthy participants. A three-back verbal working-memory task was performed befo...

journal_title：Neuroreport

authors： Ohn SH,Park CI,Yoo WK,Ko MH,Choi KP,Kim GM,Lee YT,Kim YH

更新日期：2008-01-08 00:00:00

abstract：:Ischemic stroke is the most frequent cause of long-term morbidity and mortality in the elderly worldwide. Mild hypothermia (32-35°C) has been found to have a neuroprotective effect against ischemic stroke. However, the protective mechanisms remain unclear. In the present study, we explore the neuroprotective effect of...

journal_title：Neuroreport

authors： Gao Z,Zhang Z,Bian Q,Li Y,Ma D,Liu Z,Zhang S

更新日期：2021-01-18 00:00:00

abstract：:Human brain homogenate proteins were analyzed for binding and processing activity in relation to brain beta-amyloid precursor protein (APP). The homogenate was purified by arginine-Sepharose 4B affinity chromatography, which traps proteins with affinity to certain groups of arginine residue, such as serine proteases a...

journal_title：Neuroreport

authors： Matsumoto A,Minami M,Matsumoto R

更新日期：1997-10-20 00:00:00

abstract：:To investigate how pheromonal information is processed in the rat accessory olfactory bulb, we optically imaged intrinsic signals to obtain high-resolution maps of activation induced by urinary stimulation. Application of volatile components in male urine mainly induced activation in the anterior accessory olfactory b...

journal_title：Neuroreport

authors： Sugai T,Yoshimura H,Kato N,Onoda N

更新日期：2006-11-06 00:00:00

abstract：:Early left-hemispheric brain lesions may lead to a reorganization of language into the right hemisphere. Language functions are consecutively spared, but visuospatial functions show slight deficits. Cortical 'crowding' of the right hemisphere has been suggested as an explanation for this effect, but no direct evidence...

journal_title：Neuroreport

authors： Lidzba K,Staudt M,Wilke M,Grodd W,Krägeloh-Mann I

更新日期：2006-06-26 00:00:00

abstract：:A bilateral spino-bulbo-spinal circuit conveys information from/to the male urogenital tract and perineal muscles. This is the first electrophysiological report of another descending pathway, one which conveys output from the medullary reticular formation (MRF) to activate postganglionic sympathetic fibers contained w...

journal_title：Neuroreport

authors： Johnson RD,Hubscher CH

更新日期：2000-02-07 00:00:00

abstract：:Two monkeys were trained in a delayed sequential motor task in which the time interval between events and the delay duration were either fixed or variable. Single-unit neuronal activity was recorded in the pre-supplementary motor area (pre-SMA). During the delay, we observed a gradual increase in activity (build-up pa...

journal_title：Neuroreport

authors： Akkal D,Escola L,Bioulac B,Burbaud P

更新日期：2004-06-07 00:00:00

abstract：:Humans are able to correct an ongoing movement very quickly in response to a suddenly moving target. Such fast responses possibly bypass the motor cortex and if so, one would expect that damage to the motor cortex would not greatly affect them. A group of children with congenital spastic hemiplegia were asked to move ...

journal_title：Neuroreport

authors： Smits-Engelsman BC,Rameckers EE,Duysens J

更新日期：2009-01-07 00:00:00

abstract：:To test the combined effect of high glucose and decreased Na+/K+-pump activity, a condition which closely mimics the diabetic state, on nerve ionic currents, changes in action potential and membrane current induced by high glucose in the presence of ouabain were investigated using voltage clamp analysis in rat single ...

journal_title：Neuroreport

authors： Takigawa T,Yasuda H,Terada M,Maeda K,Haneda M,Kashiwagi A,Kitasato H,Kikkawa R

更新日期：2000-08-03 00:00:00

abstract：:N-methyl-D-aspartate (NMDA) receptors are hetero-oligomeric receptor-channel complexes composed of NR1 and NR2 subunits. Subunit composition determines the properties of NMDA receptor subtypes. However, the molecular mechanisms regulating their subunit composition are unknown. Using reverse transcription (RT)-competit...

journal_title：Neuroreport

authors： Hoffmann H,Hatt H,Gottmann K

更新日期：1997-12-01 00:00:00

abstract：:Increased expression and nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) are early, critical events in several forms of apoptosis. In order to investigate the subcellular trafficking of GAPDH in vivo, the localization of a GAPDH-green fluorescent protein (GFP) fusion was studied in PC12, HEK 2...

journal_title：Neuroreport

authors： Shashidharan P,Chalmers-Redman RM,Carlile GW,Rodic V,Gurvich N,Yuen T,Tatton WG,Sealfon SC

更新日期：1999-04-06 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) was used in 17 normal individuals to modulate vestibulo-ocular reflex (VOR) and self-motion perception rotational thresholds. The electrodes were applied over the temporoparietal junction bilaterally. Both vestibular nystagmic and perceptual thresholds were increased duri...

journal_title：Neuroreport

authors： Kyriakareli A,Cousins S,Pettorossi VE,Bronstein AM

更新日期：2013-10-02 00:00:00

abstract：:We recorded auditory evoked magnetic fields (AEFs) by presenting pure tone bursts once every 4000 ms in 11 patients with a brain lesion in or in the vicinity of the auditory cortex. AEFs on the damaged side revealed several enhanced deflections in late-latency AEFs (slow AEFs), peaking at approximately 320 (DI), 1030 ...

journal_title：Neuroreport

authors： Kamada K,Takeuchi F,Harada T,Qiao B,Houkin K,Kuriki S,Iwasaki Y,Mitsumori K

更新日期：2001-05-08 00:00:00

abstract：:Chimeric mice stably reconstituted with bone marrow cells represent a good model for analysis of the mechanism of bone marrow cell infiltration in the brain. However, in preparing chimeric mice, irradiation of the recipient mice is necessary to kill their own bone marrow before transplantation, which induces gliosis a...

journal_title：Neuroreport

authors： Furuya T,Tanaka R,Urabe T,Hayakawa J,Migita M,Shimada T,Mizuno Y,Mochizuki H

更新日期：2003-03-24 00:00:00

abstract：:To confirm neural plasticity of the mouse hippocampo-prefrontal cortex (PFC) pathway, paired-pulse facilitation (PPF) and long-term potentiation (LTP) induction were determined in the pathway. In addition, we tested whether the plasticity differs in projections of the pathway from the dorsal (upper) and ventral (lower...

journal_title：Neuroreport

authors： Izaki Y,Takita M,Nomura M

更新日期：2001-05-08 00:00:00

abstract：:We aimed to ascertain whether pyrethroid insecticides could influence the vesicular transport of the excitatory amino acid glutamate. The incubation of rat cortical synaptic vesicles with resmethrin and permethrin, consistently stimulated both ATP-dependent and -independent uptake of [3H]glutamate, while not evoking d...

journal_title：Neuroreport

authors： Vaccari A,Ruiu S,Mocci I,Saba P

更新日期：1998-10-26 00:00:00

abstract：:We investigated the effects of 2,2,2-trichloroethanol (TCE), the active metabolite of chloral hydrate, on large-conductance calcium-activated K+ channels (BKCa channels) of dorsal root ganglion (DRG) neurones. In outside-out patches, 2 and 5 mM TCE increased the open probability of BKCa channels to 1.7-fold and 2.8-fo...

journal_title：Neuroreport

authors： Gruss M,Hempelmann G,Scholz A

更新日期：2002-05-07 00:00:00

abstract：:Spinally administered adenosine reduces hypersensitivity in animals and humans with nerve injury, but also causes transient pain in humans and reduces tonic inhibition in spinal neurons. Nerve injury results in increased tonic spinal cord adenosine A1 receptor activation, consistent with a role for adenosine to genera...

journal_title：Neuroreport

authors： Martin TJ,Eisenach JC,Misler J,Childers SR

更新日期：2006-10-23 00:00:00

abstract：:The purpose of the present study was to determine the cortical areas contributing to the influence of the previous movement on the current movement. Right-handed healthy human participants abducted and then adducted the left index finger in response to a start cue. Twenty consecutive trials with 10 s intertrial interv...

journal_title：Neuroreport

authors： Oda H,Sawaguchi Y,Kunimura H,Kawasaki T,Hiraoka K

更新日期：2020-12-30 00:00:00

abstract：:Dichotic pitches and mistuned harmonics can each lead to the perception of one or two auditory objects. Comparison of event-related potentials for the perception of one versus two objects reveals an early negative and a late positive component. The relationship of these components with auditory segregation was further...

journal_title：Neuroreport

authors： Hautus MJ,Johnson BW,Colling LJ

更新日期：2009-07-01 00:00:00

abstract：:Dopamine plays important functional roles in the vertebrate retina. Here we show that functional D2 dopamine receptors are present on mammalian retinal Müller (glial) cells. Using an antiserum directed to two oligopeptides predicted from rat D2 receptor DNA, patchy label was demonstrated immunocytochemically on virtua...

journal_title：Neuroreport

authors： Biedermann B,Fröhlich E,Grosche J,Wagner HJ,Reichenbach A

更新日期：1995-03-07 00:00:00

abstract：:Following brain injury astrocytes swell acutely and proliferate thereafter. To investigate the direct relationship between swelling and proliferation, cultured astroglial cells were exposed to 60 mM K+ ion or hypo-osmolar (205 mOsm) electrolyte solution for 1 h to cause transient swelling. Proliferation was assessed b...

journal_title：Neuroreport

authors： Del Bigio MR,Omara F,Fedoroff S

更新日期：1994-01-31 00:00:00

abstract：:Involuntary eye movements to foveal stimulation were measured in a monkey while it performed a fixation task. Second-order plaid motion generated higher velocities of eye movements than did first-order gratings, yet the latency of the early following response was no different for grating or plaid motion. Nevertheless,...

journal_title：Neuroreport

authors： Guo K,Benson PJ

更新日期：1999-02-05 00:00:00

abstract：:We previously reported that withdrawal from chronic cocaine produces supersensitivity of serotonin 2A receptors. We report here the minimum cocaine exposure necessary to produce withdrawal-associated increases in serotonin 2A receptor signaling in the frontal cortex. Rats withdrawn from cocaine treatments of 1, 3 or 7...

journal_title：Neuroreport

authors： Carrasco GA,Battaglia G

更新日期：2007-01-08 00:00:00

abstract：:Palmitoylethanolamine (PEA) is a ligand at peroxisome proliferator-activated receptors-α (PPARα), a nuclear receptor that has anti-inflammatory effects. Herein, complete Freund's adjuvant (CFA)-induced inflammatory pain model in rats and in-vitro calcium imaging studies were used to evaluate the mechanisms that underl...

journal_title：Neuroreport

authors： Aldossary SA,Alsalem M,Kalbouneh H,Haddad M,Azab B,Al-Shboul O,Mustafa AG,Obiedat S,El-Salem K

更新日期：2019-01-02 00:00:00

abstract：:In situ hybridization has demonstrated mRNA for olfactory receptors (OR) in the axon terminals of olfactory receptor neurons. Neurons that express the same OR appear to send their axons to two stereotyped glomeruli in the olfactory bulb (OB). Based on these observations, we tested the feasibility of using RT-PCR to is...

journal_title：Neuroreport

authors： Singer MS,Hughes TE,Shepherd GM,Greer CA

更新日期：1998-11-16 00:00:00