Population coding of movement dynamics by cerebellar Purkinje cells.

abstract：:Previous studies have established a role for N-methyl-D-aspartate receptor (NMDAR) containing the GluN2B subunit in efficient learning behavior on a variety of tasks. Recent findings have suggested that NMDAR on GABAergic interneurons may underlie the modulation of striatal function necessary to balance efficient acti...

journal_title：Neuroreport

authors： Brigman JL,Daut RA,Saksida L,Bussey TJ,Nakazawa K,Holmes A

更新日期：2015-06-17 00:00:00

abstract：:A polymorphism of the apolipoprotein E gene, in particular the epsilon 4 allele (ApoE4), has been associated with impaired neuronal phospholipid metabolism and synapse reorganization and has been implicated in several neurodegenerative disorders. Since selective neuronal cell lose and aberrant axonal reorganization re...

journal_title：Neuroreport

authors： Blümcke I,Brockhaus A,Scheiwe C,Rollbrocker B,Wolf HK,Elger CE,Wiestler OD

更新日期：1997-03-24 00:00:00

abstract：:This study investigated the functional neuroanatomy involved in retrieval of structured versus unstructured verbal information. We compared cerebral blood flow using PET with the [15O]water method while subjects engaged in recall of novel and practised narratives and lists of unrelated words. Left orbital frontal cort...

journal_title：Neuroreport

authors： Paradiso S,Crespo Facorro B,Andreasen NC,O'Leary DS,Watkins LG,Boles Ponto L,Hichwa RD

更新日期：1997-09-29 00:00:00

abstract：:Mammalian TIMELESS (TIM) was identified due to its sequence similarity to Drosophila TIM, an essential circadian clock protein in flies. Published literature is inconsistent regarding the rhythmic expression of mammalian Tim, the interaction of the TIM protein with other clock proteins and its role in regulating clock...

journal_title：Neuroreport

authors： Gotter AL

更新日期：2006-08-21 00:00:00

abstract：:Plasminogen activator inhibitor-1 is a serpin that regulates the activities of plasminogen activators. However, its physiological roles in the CNS are incompletely understood. We have found that plasminogen activator inhibitor-1 has a novel biological function in the CNS: the contribution to survival of neurites on ne...

journal_title：Neuroreport

authors： Soeda S,Imatoh T,Ochiai T,Koyanagi S,Shimeno H

更新日期：2004-04-09 00:00:00

abstract：:Bulbospinal C1 neurons are sympathoexcitatory and excited by substance P. However the substance P receptor (NK1 receptor), has been reported to be absent from the somata of C1 neurons. In this study, using double and triple labelling immunofluorescence and retrograde tracing, we provide evidence that the NK1 receptor ...

journal_title：Neuroreport

authors： Makeham JM,Goodchild AK,Pilowsky PM

更新日期：2001-12-04 00:00:00

abstract：:Complex tones such as vowels expressed by the human voice vary both in fundamental pitch (harmonic periodicity) and spectrum shape (vowel type). Three different pitches and spectra were combined into nine auditory stimuli. Latencies of cerebral evoked potential components decreased significantly as pitch increased, wh...

journal_title：Neuroreport

authors： Ragot R,Lepaul-Ercole R

更新日期：1996-03-22 00:00:00

abstract：:Antisera were produced against synthetic peptides predicted from the recent cloning of a delta opioid receptor, DOR-1. Confocal microscopic examination of immunostained spinal cord sections revealed that DOR-1 immunoreactive (-ir) nerve fibers and terminals form a moderately dense plexus within the superficial dorsal ...

journal_title：Neuroreport

authors： Dado RJ,Law PY,Loh HH,Elde R

更新日期：1993-12-13 00:00:00

abstract：:We conducted semiautomated, atlas-based analyses of regional brain volume changes on MRIs of children and adolescents with Down syndrome (DS) (N=15), DS with comorbid autism spectrum disorder (ASD) (N=15), and age-matched or sex-matched typically developing controls (N=22). Selective volumetric changes were correlated...

journal_title：Neuroreport

authors： Carter JC,Capone GT,Kaufmann WE

更新日期：2008-04-16 00:00:00

abstract：:Removal of the labyrinthine organs on one side results in static and dynamic disturbances. Some functional recovery occurs over time and is paralleled in frogs by an increase in the efficacy of central vestibular pathways. Here, we report concomitant increases in dorsal root evoked ventral root responses in the brachi...

journal_title：Neuroreport

authors： Straka H,Kunkel A,Dieringer N

更新日期：1993-09-01 00:00:00

abstract：:Intracellular recordings of activity in response to acoustic stimuli were obtained from units of the dentate nucleus of conscious cats. Twelve units with short latency responses to 70 dB clicks or hisses were injected intracellularly with biocytin and identified morphologically. The identified cells were small, relati...

journal_title：Neuroreport

authors： Xi MC,Woody CD,Gruen E

更新日期：1994-08-15 00:00:00

abstract：:Motor imagery paradigms can be used to investigate motor preparation. We used positron emission tomography to compare regional cerebral blood flow (rCBF) in patients with Parkinson's disease and normal controls under three conditions: rest, motor imagery and motor execution. In controls, imagery activated bilateral do...

journal_title：Neuroreport

authors： Samuel M,Ceballos-Baumann AO,Boecker H,Brooks DJ

更新日期：2001-03-26 00:00:00

abstract：:Levels of mRNAs encoding for the two isoforms of glutamate decarboxylase, GAD67 and GAD65, were quantified in the rat striatum and cerebral cortex following single injections of the non-competitive NMDA receptor antagonist MK-801. Acute MK-801 induced a dose-dependent decrease in GAD65 mRNA levels in ventral sectors o...

journal_title：Neuroreport

authors： Laprade N,Soghomonian JJ

更新日期：1995-10-02 00:00:00

abstract：:To clarify the time course of neural responses to faces with different emotional expressions, we used event-related potential (ERP) and reaction time measures. Faces expressing four different emotions (happy, neutral, fearful, disgusted) and houses were shown in both upright and inverted orientations while subjects pe...

journal_title：Neuroreport

authors： Ashley V,Vuilleumier P,Swick D

更新日期：2004-01-19 00:00:00

abstract：:Autopsy material from three patients with Rett syndrome and six control cases (frontal, temporal and motor cortical areas) were studied. Pyramidal and non-pyramidal neurones, 100-200 in each specimen, were visualized by Lucifer Yellow microinjection. 3-D reconstructions and rotations were computed using the VoxelView/...

journal_title：Neuroreport

authors： Belichenko PV,Oldfors A,Hagberg B,Dahlström A

更新日期：1994-07-21 00:00:00

abstract：:Ciliary neurotrophic factor (CNTF) attracts considerable attention because it supports survival and differentiation of various types of neurons and glial cells in vitro. Although CNTF functions as a moderate neurotrophic factor in mature motor neurons, its role in embryonic development remains unknown. Here, we found ...

journal_title：Neuroreport

authors： Hata K,Araki M,Yamamori T

更新日期：2002-04-16 00:00:00

abstract：:This study aimed to examine the spontaneous hemodynamic fluctuations and the dysfunctional brain regions in patients with generalized anxiety disorder (GAD) using resting-state functional MRI. Previous studies have demonstrated some neural networks that are different in this patient group compared with healthy control...

journal_title：Neuroreport

authors： Li C,Su S,Wu H,Zhu Y

更新日期：2018-03-21 00:00:00

abstract：:Inflammatory and immune responses are known to be involved in the pathogenesis of Alzheimer's disease (AD). NF-kappaB is a major transcription factor that plays a central role in the inflammatory and immune responses and is regulated by I-kappaB through an autoregulatory feedback system. Southwestern immunohistochemis...

journal_title：Neuroreport

authors： Yoshiyama Y,Arai K,Hattori T

更新日期：2001-08-28 00:00:00

abstract：:Phosphorus magnetic resonance spectroscopy was used to determine effects of acute and chronic alcohol exposure on brain intracellular free magnesium concentration (Mgf) and bioenergetic state in rats. Acute alcohol (3 mg kg-1, i.p.) resulted in a transient ( < 2h) decline in brain Mgf and cytosolic phosphorylation rat...

journal_title：Neuroreport

authors： Mullins PG,Vink R

更新日期：1995-08-21 00:00:00

abstract：:This study aimed to investigate effects of observing the own body being touched on the functional topography of the somatosensory homunculus. We used neuromagnetic source imaging to map the topography in primary somatosensory cortex (SI) while manipulating the visibility of a touched hand. Participants were either abl...

journal_title：Neuroreport

authors： Schaefer M,Heinze HJ,Rotte M

更新日期：2008-06-11 00:00:00

abstract：:To investigate the neural substrates for the perception of motion and of position in depth, we examined the changes in regional cerebral blood flow during positional and motion stereopsis in humans by positron emission tomography. During positional stereopsis, the right striate and peristriate cortices (areas V1/V2 an...

journal_title：Neuroreport

authors： Nagahama Y,Takayama Y,Fukuyama H,Yamauchi H,Matsuzaki S,Magata Y,Shibasaki H,Kimura J

更新日期：1996-07-29 00:00:00

abstract：:In this study, an algorithm is introduced for the automatic detection and simultaneous topographic classification of interictal regional spike activity in pediatric surface EEG records. The algorithm is based on the classification of the topographic distribution of instantaneous power by means of a 'group' trained cla...

journal_title：Neuroreport

authors： Feucht M,Hoffmann K,Steinberger K,Witte H,Benninger F,Arnold M,Doering A

更新日期：1997-07-07 00:00:00

abstract：:Music is an essential communication tool that can convey emotional information. Segmentation of a sound stream of music at event boundaries is necessary for identification and extraction of musical context and features. To investigate recognition of music termination structure, or cadence, we composed music sequences ...

journal_title：Neuroreport

authors： Hoshi-Shiba R,Furukawa K,Okanoya K

更新日期：2014-07-09 00:00:00

abstract：:Human short-latency cortical responses to median nerve stimulation were investigated with a new high resolution electroencephalography technology that markedly enhanced spatial details of somatosensory-evoked potentials (SEPs). Maximum amplitude potentials were estimated over contralateral and/or frontal-mesial scalp ...

journal_title：Neuroreport

authors： Urbano A,Babiloni F,Babiloni C,Ambrosini A,Onorati P,Rossini PM

更新日期：1997-10-20 00:00:00

abstract：:Single-pulse unilateral electrical stimulation of either the amygdala or the inferior colliculus elicited startle-like responses in chloral hydrate anesthetized rats. EMG responses to intracranial stimulation were recorded from the anterior biceps femoris muscles. The EMG responses were generally enhanced following un...

journal_title：Neuroreport

authors： Lin C,Wan X,Zhao W,Ma C,Ma C,Gao Y,Zhou Y,Yeomans JS,Li L

更新日期：2002-10-07 00:00:00

abstract：:This study examined 'prepulse inhibition' in the context of an auditory two-tone discrimination task performed by 15 healthy subjects. In order to distinguish between masking or excitatory information processes, weak acoustic pulses immediately preceded or succeeded a target or non-target tone in the discrimination. B...

journal_title：Neuroreport

authors： Schall U,Ward PB

更新日期：1996-01-31 00:00:00

abstract：:In an earlier study, we reported the antinociceptive effects of a special repetitive transcranial magnetic stimulation paradigm: continuous theta-burst stimulation (cTBS), when applied to human motor cortex. Here, we investigated whether the reduced subjective pain perception of 10 healthy individuals could be measure...

journal_title：Neuroreport

authors： Csifcsak G,Nitsche MA,Baumgärtner U,Paulus W,Treede RD,Antal A

更新日期：2009-08-05 00:00:00

abstract：:The most important risk factor for developing Parkinson's disease (PD) is age. Aging is ascribed to different mechanisms, including telomere shortening. Telomeres consist of repetitive DNA sequences and stabilize chromosome integrity. Currently, however, the data reported on telomere shortening in PD patients are inco...

journal_title：Neuroreport

authors： Oeckl P,Scheffold A,Lechel A,Rudolph KL,Ferger B

更新日期：2014-03-26 00:00:00

abstract：:Regional variation in the distribution of SP and NFT within the brain is well documented. Consideration of such variation is potentially of help in formulating models of disease progression. Several models propose that pathological changes in Alzheimer's disease (AD) progress in a step-wise fashion along neuronally co...

journal_title：Neuroreport

authors： Shukla C,Bridges LR

更新日期：1999-12-16 00:00:00

abstract：:Activated NF-kappaB contributes to cerebral infarction by triggering a neuro-inflammatory response. Rats subjected to 90min middle cerebral artery occlusion developed a cortical infarct of 20+/-4% of hemispheric volume (n = 8). Treatment with the proteasome inhibitor CVT-634 resulted in a significantly smaller infarct...

journal_title：Neuroreport

authors： Buchan AM,Li H,Blackburn B

更新日期：2000-02-07 00:00:00