Abstract:
:In an earlier study, we reported the antinociceptive effects of a special repetitive transcranial magnetic stimulation paradigm: continuous theta-burst stimulation (cTBS), when applied to human motor cortex. Here, we investigated whether the reduced subjective pain perception of 10 healthy individuals could be measured by changes in laser-evoked potentials, a reflection of pain related activations in the operculoinsular and midcingulate cortex. To minimize the effect of habituation during repeated laser stimulation, a bioadaptive design was used. However, both pain ratings and laser-evoked potential amplitudes were reduced after real and sham cTBS. When compared with sham stimulation, cTBS resulted in a significantly greater diminution of pain ratings and N2-P2 amplitudes on the hand contralateral to the site of motor cortex stimulation.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Csifcsak G,Nitsche MA,Baumgärtner U,Paulus W,Treede RD,Antal Adoi
10.1097/WNR.0b013e32832e0c74subject
Has Abstractpub_date
2009-08-05 00:00:00pages
1051-5issue
12eissn
0959-4965issn
1473-558Xpii
00001756-200908050-00003journal_volume
20pub_type
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