Abstract:
:Ciliary neurotrophic factor (CNTF) attracts considerable attention because it supports survival and differentiation of various types of neurons and glial cells in vitro. Although CNTF functions as a moderate neurotrophic factor in mature motor neurons, its role in embryonic development remains unknown. Here, we found a specific CNTF expression in the rat pineal gland and eyes during embryonic development. In vitro, neonatal rat pineal extract including CNTF supported the survival of neonatal sympathetic neurons, which innervate pineal glands immediately after birth.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Hata K,Araki M,Yamamori Tdoi
10.1097/00001756-200204160-00039subject
Has Abstractpub_date
2002-04-16 00:00:00pages
735-9issue
5eissn
0959-4965issn
1473-558Xjournal_volume
13pub_type
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