Electrophysiological correlates of hypothesis testing.

abstract：:The anxiolytic-like potential of anpirtoline was assessed in a mouse light/dark aversion test. Anpirtoline (1.0 ng kg(-1)-1.0 micrograms kg-1 i.p.) reduced the aversive responding of mice. This was detected as an increase in the latency to locate the non-aversive compartment and by decreases in the percentage of the t...

journal_title：Neuroreport

authors： Metzenauer P,Barnes NM,Costall B,Gozlan H,Hamon M,Kelly ME,Murphy DA,Naylor RJ

更新日期：1992-06-01 00:00:00

abstract：:The present study explored duration mismatch negativity (MMN) reduction in schizophrenia. Duration MMN studies usually employ tones of very short duration (< 200 ms). For stimuli < 200 ms in duration, an increment in duration is accompanied by an increase in perceived loudness. It was previously proposed that the effe...

journal_title：Neuroreport

authors： Todd J,Michie PT,Jablensky AV

更新日期：2001-12-21 00:00:00

abstract：:We have used double quantum filtered (DQF) 23Na+ nuclear magnetic resonance (NMR) spectroscopy without shift reagents in order to monitor intracellular Na+ (Na+i) in a cortical brain slice preparation. The external Na+ (Na+o) signal was reduced by 95% by the DQF sequence compared with the directly observed 23Na+. The ...

journal_title：Neuroreport

authors： Brooks KJ,Pirttilä TR,Kauppinen RA

更新日期：1993-02-01 00:00:00

abstract：:A combined microdialysis/microinfusion technique was used to investigate whether arginine vasopressin (AVP) is involved in the regulation of its own release into the extracellular fluid of the supraoptic nucleus in vivo. While intranuclear neuropeptide release was monitored, 0.33 microliter of either vehicle, lysine v...

journal_title：Neuroreport

authors： Wotjak CT,Ludwig M,Landgraf R

更新日期：1994-06-02 00:00:00

abstract：:Sound localization can be affected by vision; in the ventriloquism effect, sounds that are hard to localize within hearing become mislocalized toward the location of concurrent visual events. Here we tested whether spatial attention is drawn to the illusory location of a ventriloquized sound. The study exploited our p...

journal_title：Neuroreport

authors： Spence C,Driver J

更新日期：2000-06-26 00:00:00

abstract：:The 29 amino acid neuropeptide galanin is normally expressed in < 5% of sensory neurons in the adult dorsal root ganglia. After nerve transection (axotomy), the galanin content of the dorsal root ganglia rises 120-fold and the peptide is then expressed in > 50% of neurons. Published data suggest that galanin plays a r...

journal_title：Neuroreport

authors： Bacon A,Holmes FE,Small CJ,Ghatei M,Mahoney S,Bloom S,Wynick D

更新日期：2002-11-15 00:00:00

abstract：:Prism adaptation reduces some symptoms of neglect; however the mechanisms underlying such changes are poorly understood. We suggest that prisms influence neglect by acting on dorsal stream circuits subserving visuomotor control, with little influence on perceptual aspects of neglect. We examined prism adaptation in th...

journal_title：Neuroreport

authors： Striemer CL,Danckert J

更新日期：2010-04-21 00:00:00

abstract：:The regulation of glucocorticoid receptors and nuclear factor kappaB was evaluated in the spiral ganglion neurons after 4 h of restraint stress in the mouse cochlea. Immediately after restraint stress, glucocorticoid receptor protein expression was not altered in spiral ganglion neurons even though both the plasma cor...

journal_title：Neuroreport

authors： Tahera Y,Meltser I,Johansson P,Canlon B

更新日期：2006-06-26 00:00:00

abstract：:Pharmacological manipulation of brain dopamine concentration affects visuospatial working memory in humans and in animals, the latter effects localized to the prefrontal cortex. However, the effects of dopamine agonists on humans are poorly understood. We hypothesized that bromocriptine would have an effect on cogniti...

journal_title：Neuroreport

authors： Kimberg DY,D'Esposito M,Farah MJ

更新日期：1997-11-10 00:00:00

abstract：:Although prenatal stress has been repeatedly shown to inhibit adult neurogenesis in the dentate gyrus of offspring, its effects on embryonic and early postnatal brain development are not well described. Here, using the cell proliferation marker 5-bromo-2'-deoxyuridine, we examine for the first time the effect of prena...

journal_title：Neuroreport

authors： Kawamura T,Chen J,Takahashi T,Ichitani Y,Nakahara D

更新日期：2006-10-02 00:00:00

abstract：:Recent studies have demonstrated a loss of cannabinoid CB1 receptors in the basal ganglia in Huntington's disease (HD), but there are no data on endocannabinoid levels in this disease. In the present study, we have addressed this question by using rats with bilateral intrastriatal injections of 3-nitropropionic acid (...

journal_title：Neuroreport

authors： Lastres-Becker I,Fezza F,Cebeira M,Bisogno T,Ramos JA,Milone A,Fernández-Ruiz J,Di Marzo V

更新日期：2001-07-20 00:00:00

abstract：:This study aimed to investigate effects of observing the own body being touched on the functional topography of the somatosensory homunculus. We used neuromagnetic source imaging to map the topography in primary somatosensory cortex (SI) while manipulating the visibility of a touched hand. Participants were either abl...

journal_title：Neuroreport

authors： Schaefer M,Heinze HJ,Rotte M

更新日期：2008-06-11 00:00:00

abstract：:Ciliary neurotrophic factor (CNTF), leukaemia inhibitory factor (LIF), oncostatin M (OSM), interleukin-6 (IL-6), and interleukin-11 (IL-11) are structurally and functionally related cytokines. We compared their survival-promoting activities on embryonic chick and newborn rat dorsal root ganglion (DRG) neurones. Human ...

journal_title：Neuroreport

authors： Simon R,Thier M,Krüttgen A,Rose-John S,Weiergräber O,Heinrich PC,Schröder JM,Weis J

更新日期：1995-12-29 00:00:00

abstract：:4-Aminobenzovesamicol was used to test whether activation of protein kinase C protects the vesicular acetylcholine transporter from interaction with vesamicol-like drugs. The essentially irreversible vesamicol analog inhibits the release of newly synthesized [3H]acetylcholine from stimulated hippocampal slices. Prior ...

journal_title：Neuroreport

authors： Clarizia AD,Gomez MV,Romano-Silva MA,Parsons SM,Prado VF,Prado MA

更新日期：1999-09-09 00:00:00

abstract：:Short-latency ocular following responses in monkeys, induced by first- and second-order motion during a fixation task, were sensitive to stimulus size, retinal eccentricity and motion duration. Latency of eye movements was no different for first- or second-order motion and simply marked the occurrence of movement in t...

journal_title：Neuroreport

authors： Benson PJ,Guo K

更新日期：1998-12-01 00:00:00

abstract：:Thyroid hormones, which play an important role in the development and regeneration of the nervous system, require the presence of specific nuclear T3 receptors (NT3R). In this study we provide evidence that NT3R expression by Schwann cells was up-regulated in response to a loss of axonal contact in vitro and in vivo. ...

journal_title：Neuroreport

authors： Walter IB

更新日期：1993-11-18 00:00:00

abstract：:Topiramate is a structurally novel neurotherapeutic agent with a unique combination of pharmacological properties and currently is available in most world markets for treating several seizure disorders. Because its pharmacological profile was suggestive of possible activity as a neuroprotectant, topiramate was evaluat...

journal_title：Neuroreport

authors： Smith-Swintosky VL,Zhao B,Shank RP,Plata-Salaman CR

更新日期：2001-04-17 00:00:00

abstract：:The steady-state visual evoked potential (SSVEP) is a powerful tool to study basic perceptual functions in the human electroencephalogram (EEG) (e.g. selective attention). The present study aimed at finding support for the SSVEP's sensitivity to higher cognitive functions (e.g. memory). We tagged pictures of meaningle...

journal_title：Neuroreport

authors： Martens U,Gert AL,Gruber T

更新日期：2012-04-18 00:00:00

abstract：:The effect of centrally administered bombesin on core temperature was investigated in rats which had been chronically fitted with a cannula in the third cerebral ventricle and with an intraperitoneal temperature-monitoring radiotransmitter. Intracerebroventricularly administered bombesin (0.01, 0.1 or 1 microgram) res...

journal_title：Neuroreport

authors： Persaud RA,Coen CW

更新日期：1994-03-21 00:00:00

abstract：:The in-vivo extracellular release of acetylcholine (ACh) from the striatum of rats was measured by intracerebral microdialysis. The ACh levels were first estimated under normoxic conditions, after which the rats were exposed to either 10% or 5% oxygen for 1 h. The average ACh content was 2.9 pmol/20 min. During hypoxi...

journal_title：Neuroreport

authors： Chleide E,Ishikawa K

更新日期：1990-11-01 00:00:00

abstract：:The effect of systemic treatment with 1-aminocyclopro-panecarboxylic acid (ACPC), a partial agonist at the glycine site of the NMDA receptor, on convulsions and neurodegeneration induced by intrahippocampal injection of NMDA was investigated in mice. Five days after intrahippocampal NMDA infusion, 80-100% pyramidal ce...

journal_title：Neuroreport

authors： Zapata A,Capdevila JL,Viu E,Trullas R

更新日期：1996-01-31 00:00:00

abstract：:We investigated the effects of radio frequency electromagnetic fields on brain physiology. Twenty-four healthy young men were exposed for 30 min to pulse-modulated or continuous-wave radio frequency electromagnetic fields (900 MHz; peak specific absorption rate 1 W/kg), or sham exposed. During exposure, participants p...

journal_title：Neuroreport

authors： Regel SJ,Gottselig JM,Schuderer J,Tinguely G,Rétey JV,Kuster N,Landolt HP,Achermann P

更新日期：2007-05-28 00:00:00

abstract：:When we perform a visually guided reaching action, the brain coordinates our hand and eye movements. Eye-hand coordination has been examined widely, but it remains unclear whether the hand and eye motor systems are coordinated during on-line visuomotor adjustments induced by a target jump during a reaching movement. A...

journal_title：Neuroreport

authors： Abekawa N,Inui T,Gomi H

更新日期：2014-05-07 00:00:00

abstract：:Microglia are activated by amyloid beta (Abeta) in vivo and in vitro, and Abeta-activated microglia may be involved in the pathogenesis of Alzheimer's disease (AD). We investigated the mechanism of microglial chemotaxis induced by Abeta (25-35), an active fragment of Abeta. Abeta (25-35) 0.1 and 1 nM stimulated microg...

journal_title：Neuroreport

authors： Nakai M,Hojo K,Taniguchi T,Terashima A,Kawamata T,Hashimoto T,Maeda K,Tanaka C

更新日期：1998-10-26 00:00:00

abstract：:Episodic memory for simple commands is better following enacted than verbal encoding. This has been proposed to be due to the possibility to base retrieval on motor information. Here we used PET to test the hypothesis that motor brain areas show increased retrieval-related activity following enacted compared to verbal...

journal_title：Neuroreport

authors： Nilsson LG,Nyberg L,Klingberg T,Aberg C,Persson J,Roland PE

更新日期：2000-07-14 00:00:00

abstract：:Two developmental disorders, autism and Williams syndrome, are both commonly described as having difficulties in integrating perceptual features, i.e. binding spatially separate elements into a whole. It is already known that healthy adults and infants display electroencephalographic (EEG) gamma-band bursts (around 40...

journal_title：Neuroreport

authors： Grice SJ,Spratling MW,Karmiloff-Smith A,Halit H,Csibra G,de Haan M,Johnson MH

更新日期：2001-08-28 00:00:00

abstract：:Recent studies have shown the nutrient-sensing systems transmitting nutritive information from the gut to the brain. However neural activity evoked by ingested dietary nutrients has not been investigated adequately. Using functional magnetic resonance imaging, we demonstrated that rat forebrain responded to intragastr...

journal_title：Neuroreport

authors： Tsurugizawa T,Kondoh T,Torii K

更新日期：2008-07-16 00:00:00

abstract：:This study used functional magnetic resonance imaging to characterize hemodynamic activation patterns recruited when the participants viewed mixed social communicative messages during a common interpersonal exchange. Mixed messages were defined as conflicting sequences of biological motion and facial affect signals th...

journal_title：Neuroreport

authors： Zucker NL,Green S,Morris JP,Kragel P,Pelphrey KA,Bulik CM,LaBar KS

更新日期：2011-06-22 00:00:00

abstract：:Beta-N-methylamino-L-alanine (BMAA) is a nonprotein amino acid that may be involved in neurodegenerative diseases. It is produced by a large variety of cyanobacteria and is found at high levels in the brains of Alzheimer's disease and amyotrophic lateral sclerosis patients. Although BMAA is clearly a neurotoxin, previ...

journal_title：Neuroreport

authors： Liu XQ,Rush T,Ciske J,Lobner D

更新日期：2010-01-06 00:00:00

abstract：:The present study examined the distribution in the human spinal cord of a unique carboxy terminus sequence contained within MOR-1C, one of the recently described splice variants of the cloned mu opioid receptor gene MOR-1. Although MOR-1-like immunoreactivity (LI) and delta opioid receptor-like immunoreactivity were o...

journal_title：Neuroreport

authors： Abbadie C,Gultekin SH,Pasternak GW

更新日期：2000-06-26 00:00:00