Short-latency ocular following of motion by monkeys during a fixation task.

abstract：:Beta-N-methylamino-L-alanine (BMAA) is a nonprotein amino acid that may be involved in neurodegenerative diseases. It is produced by a large variety of cyanobacteria and is found at high levels in the brains of Alzheimer's disease and amyotrophic lateral sclerosis patients. Although BMAA is clearly a neurotoxin, previ...

journal_title：Neuroreport

authors： Liu XQ,Rush T,Ciske J,Lobner D

更新日期：2010-01-06 00:00:00

abstract：:Duchenne muscular dystrophy is due to mutations in the dystrophin gene which is predominantly expressed in muscle and brain. Since the disease is associated with cognitive impairment, we sought to localize dystrophin mRNA in brain using in situ hybridization with oligonucleotide probes. We find the gene strongly expre...

journal_title：Neuroreport

authors： Gorecki D,Geng Y,Thomas K,Hunt SP,Barnard EA,Barnard PJ

更新日期：1991-12-01 00:00:00

abstract：:Perceptual regularities have been investigated intensely in music research but to a lesser extent in speech research possibly because of its irregular nature. People tend to rhythmize almost every given acoustic input though, even if one stimulus is physically identical to the next. Hence, perception of regularities s...

journal_title：Neuroreport

authors： Schmidt-Kassow M,Kotz SA

更新日期：2009-12-09 00:00:00

abstract：:The serum-free mouse embryo (SFME) cell line, derived from 16-day-old mouse embryos in medium in which serum was replaced by growth factors and other supplements, has been cultured for more than 200 generations. SFME cells are nontumorigenic, lack gross chromosomal abnormalities, and display characteristics of CNS pro...

journal_title：Neuroreport

authors： Loo DT,Althoen MC,Cotman CW

更新日期：1994-08-15 00:00:00

abstract：:Prolonged activation of brain N-methyl-D-aspartic acid (NMDA) receptors increases intraneuronal (Ca2+) and nitric oxide (NO) synthesis, and may be responsible for neuronal death in acute brain insults and chronic neurodegenerative diseases. NO can be converted in vitro to toxic hydroxyl (OH) radical. Using microdialys...

journal_title：Neuroreport

authors： Hammer B,Parker WD Jr,Bennett JP Jr

更新日期：1993-10-25 00:00:00

abstract：:BALB/c mice were trained in a partial acquisition session of an appetitive bar-pressing task. They then received an immediate post-acquisition i.p. injection of either saline or apamin 0.2 mg kg-1. Each group was submitted to a retention test that was delayed either 25, 85 or 180 min after initial acquisition. In sali...

journal_title：Neuroreport

authors： Belcadi-Abbassi W,Destrade C

更新日期：1995-06-19 00:00:00

abstract：:Mitochondrial dysfunction and oxidative stress are implicated in the pathological changes observed in the diabetic central nervous system. In this study, using the streptozotocin-induced diabetic rat model we document for the first time the over-expression of a mitochondrial specific stress protein (chaperonin 60) in ...

journal_title：Neuroreport

authors： Yuan J,Young BJ,Martinus RD

更新日期：2006-02-27 00:00:00

abstract：:Canine degenerative myelopathy (DM) is a fatal neurodegenerative disorder prevalent in the canine population. It may represent a unique, naturally occurring disease model for human amyotrophic lateral sclerosis (ALS) because of similar clinical signs and association with superoxide dismutase 1 gene (SOD1) mutations. M...

journal_title：Neuroreport

authors： Chang RC,Parakh S,Coates JR,Long S,Atkin JD

更新日期：2019-01-02 00:00:00

abstract：:Skin sensory nerve nocifensor functions were investigated non-invasively in rats by measuring neurogenic inflammation and blister healing-rate after unilateral hindlimb denervation. Axon reflexes were evoked by transdermal iontophoresis of acetylcholine (ACh) or noxious electrical stimulation (TNS). Sodium nitroprussi...

journal_title：Neuroreport

authors： Carr RW,Delaney CA,Westerman RA,Roberts RG

更新日期：1993-05-01 00:00:00

abstract：:The effect of an ischaemic focal cortical lesion on the excitability of surrounding and remote brain areas was investigated. Infarcts were produced photothrombotically in rat frontal cortex and brain excitability was assessed by a extracellular paired-pulse stimulation in coronal slices 7 days later. The cortical lesi...

journal_title：Neuroreport

authors： Buchkremer-Ratzmann I,Witte OW

更新日期：1997-01-20 00:00:00

abstract：:To investigate the phonological influences on the lexicosemantic process with a strong orthographic constraint, we used kanji (morphogram) homophone words and measured, using magnetoencephalography, the neural activities during the silent reading of prime-target pairs. The primes were phonologically the same as or dif...

journal_title：Neuroreport

authors： Wei Q,Ihara A,Hayakawa T,Murata T,Matsumoto E,Fujimaki N

更新日期：2007-11-19 00:00:00

abstract：:Nerve growth factor (NGF) promotes the survival of several neuronal populations, but recently it has also been shown to induce neuronal cell death. Here we report the effects of NGF on lesioned motoneurons. We have analyzed facial and sciatic motoneurons in newborn and adult BALB/c and C57BL/6 mice, in addition to mic...

journal_title：Neuroreport

authors： Terrado J,Monnier D,Perrelet D,Sagot Y,Mattenberger L,King B,Kato AC

更新日期：2000-05-15 00:00:00

abstract：OBJECTIVE:The traditional Chinese medicine, Dendrobium nobile Lindl. polysaccharides (DNLP), reportedly has neuroprotective effects. However, its effects following ischemic stroke remain unclear. This study aimed to explore the role and mechanism of DNLP in experimental models of inflammation and apoptosis. METHODS:In...

journal_title：Neuroreport

authors： Liu J,Han Y,Zhu T,Yang Q,Wang H,Zhang H

更新日期：2020-12-14 00:00:00

abstract：:Experimental animals and patients are immobilized to allow continuous monitoring of physiological parameters. Restraint stress affects brain neurotransmitter levels and induces expression of immediate early genes. Whether immobilization stress affects outcomes in newborn animals which have suffered a hypoxic-ischaemic...

journal_title：Neuroreport

authors： Thoresen M,Bågenholm R,Løberg EM,Apriccna F

更新日期：1996-01-31 00:00:00

abstract：:Somatosensory evoked fields were recorded to determine the effects of movement and attention on high-frequency oscillations during active finger movements of the ipsilateral and contralateral sides in response to electrical stimulation of the median nerve. A whole-scalp neuromagnetometer was used to record somatosenso...

journal_title：Neuroreport

authors： Inoue K,Harada T,Kaseda Y,Mimori Y,Hashizume A,Hashimoto I,Matsumoto M

更新日期：2002-10-28 00:00:00

abstract：:Subthalamic nucleus (STN) hyperactivity follows lesions of mesencephalic dopaminergic neurons in animal models of Parkinson's disease. The mechanism leading to sustained STN hyperactivity in parkinsonism is not well understood, but it seems not to depend on the integrity of striato-pallido-subthalamic connections (the...

journal_title：Neuroreport

authors： Murer MG,Ferrario J,Delfino M,Dziewczapolski G,Gershanik OS,Raisman-Vozari R

更新日期：1999-05-14 00:00:00

abstract：:The Flinders sensitive line of rats is a widely accepted and validated model of depression. These rats demonstrate abnormalities in limbic dopamine neurotransmission, suggesting disturbed neuronal activity in the ventral tegmental area. Interspike interval time-series were recorded from the ventral tegmental area of c...

journal_title：Neuroreport

authors： Dremencov E,Nahshoni E,Levy D,Mintz M,Overstreet DH,Weizman A,Yadid G

更新日期：2004-08-26 00:00:00

abstract：:Basic FGF mRNA induction by bFGF was investigated in cell cultures from rat brain, i.e. postnatal day 2 cortex and embryonic day 18 hippocampus. In situ hybridization shows that after bFGF treatment (10(-10) M) for 14 h neurones and glial cells show a remarkable increase in bFGF mRNA production. Incubation of astrocyt...

journal_title：Neuroreport

authors： Flott-Rahmel B,Gerdes W,Pechan PA,Brysch W,Schlingensiepen KH,Seifert W

更新日期：1992-12-01 00:00:00

abstract：:We previously reported that the methanol extract of Ashwagandha (roots of Dunal) induced dendrite extension in a human neuroblastoma cell line. In this study, we found that six of the 18 compounds isolated from the methanol extract enhanced neurite outgrowth in human neuroblastoma SH-SY5Y cells. Double immunostaining ...

journal_title：Neuroreport

authors： Kuboyama T,Tohda C,Zhao J,Nakamura N,Hattori M,Komatsu K

更新日期：2002-10-07 00:00:00

abstract：:Neuroimaging techniques, such as fMRI, PET and near-infrared spectroscopy, monitor task-related neuronal activations in the brain indirectly through the associated neurovascular/metabolic responses. To assess the primary neuronal activations directly, magnetoencephalography was combined here with a mechanical modulati...

journal_title：Neuroreport

authors： Mackert BM,Wübbeler G,Leistner S,Trahms L,Curio G

更新日期：2001-06-13 00:00:00

abstract：:AMPA-preferring glutamate receptor genes gluR1-4 undergo alternative splicing into flip and flop mRNA isoforms. In the rodent hippocampus, gluR1 and gluR2 isoforms are differentially expressed. We have studied their distribution in human hippocampus. As in the rat, flop isoforms predominate over flip in dentate gyrus,...

journal_title：Neuroreport

authors： Eastwood SL,Burnet PW,Beckwith J,Kerwin RW,Harrison PJ

更新日期：1994-06-27 00:00:00

abstract：:N-methyl-D-aspartate (NMDA) receptors are hetero-oligomeric receptor-channel complexes composed of NR1 and NR2 subunits. Subunit composition determines the properties of NMDA receptor subtypes. However, the molecular mechanisms regulating their subunit composition are unknown. Using reverse transcription (RT)-competit...

journal_title：Neuroreport

authors： Hoffmann H,Hatt H,Gottmann K

更新日期：1997-12-01 00:00:00

abstract：:Diabetic peripheral neuropathy is the most common complication of diabetes mellitus and leads to sensory symptoms, including diabetic neuropathic pain (DNP). DNP is a major public health problem because it has a considerable impact on life quality of diabetes mellitus patients. Therefore, development of novel effectiv...

journal_title：Neuroreport

authors： Li P,Xiong DL,Sun WP,Xu SY

更新日期：2018-12-05 00:00:00

abstract：:Previous research has suggested that exposure to radiofrequency electromagnetic fields increases electroencephalogram spectral power in non-rapid eye movement sleep. Other sleep parameters have also been affected following exposure. We examined whether aspects of sleep architecture show sensitivity to electromagnetic ...

journal_title：Neuroreport

authors： Loughran SP,Wood AW,Barton JM,Croft RJ,Thompson B,Stough C

更新日期：2005-11-28 00:00:00

abstract：:The pattern of distribution and co-localization of nitric oxide synthase (NOS) and quinacrine fluorescence (indicative of vesicular adenosine 5'-triphosphate, ATP), and co-localization of NADPH-diaphorase (NADPH-d) activity and NOS-immunoreactivity in the myenteric plexus of pre-term human fetal (6-17 weeks of gestati...

journal_title：Neuroreport

authors： Belai A,Burnstock G

更新日期：2000-01-17 00:00:00

abstract：:It has been hypothesized that the vomeronasal system (VNS), a complex neural network implicated in the control of reproductive behaviors, is sexually dimorphic. The posteromedial cortical amygdaloid nucleus (PMCo) belongs to the group of amygdaloid structures that receive direct olfactory input from the accessory olfa...

journal_title：Neuroreport

authors： Vinader-Caerols C,Collado P,Segovia S,Guillamón A

更新日期：1998-08-03 00:00:00

abstract：:MicroRNAs (miRNAs) have been documented as critical regulators in ischemia/reperfusion-induced neuronal death. A better understanding of miRNA-mediated molecular mechanisms in ischemia/reperfusion-induced neuronal death may provide therapeutic targets for cerebral ischemia/reperfusion injury. A growing body of evidenc...

journal_title：Neuroreport

authors： Xiao J,Kong R,Hu J

更新日期：2018-06-13 00:00:00

abstract：:Previous studies in adult rats have demonstrated that the neurotrophin, brain-derived neurotrophic factor (BDNF), is present in virtually all cells of the pituitary intermediate lobe. In the present study, we demonstrate that cells cultured from adult intermediate lobe pituitary (ILP) rapidly lose their BDNF immunorea...

journal_title：Neuroreport

authors： Höpker VH,Kjaer B,Varon S

更新日期：1997-03-24 00:00:00

abstract：:GLYX-13 (threonine-proline-proline-threonine-amide) is an amidated di-pyrrolidine that acts as a functional partial agonist at the glycine site on N-methyl-D-aspartate glutamate receptors (NMDARs). GLYX-13 can both increase NMDAR conductance at NR2B-containing receptors, and reduce conductance of non-NR2B-containing r...

journal_title：Neuroreport

authors： Stanton PK,Potter PE,Aguilar J,Decandia M,Moskal JR

更新日期：2009-08-26 00:00:00

abstract：:In this study we investigated the utility of different MRI techniques for the detection and predictability of hemorrhagic transformation (HT) in a rat model of transient focal cerebral ischemia. Hemorrhagic infarction was reliably identified with gradient-echo sequences and developed between 2 and 7 days following the...

journal_title：Neuroreport

authors： Neumann-Haefelin T,Kastrup A,de Crespigny A,Ringer TM,Sun GH,Yenari MA,Moseley ME

更新日期：2001-02-12 00:00:00