Expression of the dystrophin gene in mouse and rat brain.

abstract：:Alpha-Synuclein is a major component of neuronal and glial cytoplasmic inclusions in multiple system atrophy (MSA), one of the alpha-synucleinopathies. Recent studies have shown that beta-synuclein, a homolog of alpha-synuclein, inhibits alpha-synuclein aggregation in vitro. We immunohistochemically examined the MSA b...

journal_title：Neuroreport

authors： Mori F,Nishie M,Yoshimoto M,Takahashi H,Wakabayashi K

更新日期：2003-10-06 00:00:00

abstract：:The potential neuroprotective effects of glial cell line-derived neurotrophic factor (GDNF) and neublastin (NBN) against NMDA-induced excitotoxicity were examined in hippocampal brain slice cultures. Recombinant human GDNF (25-100 ng/ ml) or NBN, in medium conditioned by growth of transfected, NBN-producing HiB5 cells...

journal_title：Neuroreport

authors： Bonde C,Kristensen BW,Blaabjerg M,Johansen TE,Zimmer J,Meyer M

更新日期：2000-12-18 00:00:00

abstract：:Following ventral root avulsion in neonatal animals, the degeneration of spinal motoneurons occurs by an apoptotic-like morphological pathway. In adult animals, however, the mechanism of degeneration of injured motoneurons is still controversial. Because caspases are important mediators of apoptosis, we have investiga...

journal_title：Neuroreport

authors： Chan YM,Wu W,Yip HK,So KF,Oppenheim RW

更新日期：2001-03-05 00:00:00

abstract：:The orientation biases seen in the responses of neurones of the dorsal lateral geniculate nucleus (dLGN) can be reduced by the local application of the GABA antagonist, bicuculline methiodide. This fact was exploited to investigate whether these biases are important for cortical orientation selectivity by measuring th...

journal_title：Neuroreport

authors： Vidyasagar TR

更新日期：1992-02-01 00:00:00

abstract：:Complex tones such as vowels expressed by the human voice vary both in fundamental pitch (harmonic periodicity) and spectrum shape (vowel type). Three different pitches and spectra were combined into nine auditory stimuli. Latencies of cerebral evoked potential components decreased significantly as pitch increased, wh...

journal_title：Neuroreport

authors： Ragot R,Lepaul-Ercole R

更新日期：1996-03-22 00:00:00

abstract：:Insulin-like growth factor-1 (IGF-1) and erythropoietin (EPO) are induced in brain cells after brain ischemia and show synergistic neuroprotective effects. In LN215 astrocytoma cells, IGF-1 induced the activation of hypoxia-inducible factor-1, leading to increases in EPO mRNA levels and the secretion of EPO. Interesti...

journal_title：Neuroreport

authors： Kim I,Kim CH,Yim YS,Ahn YS

更新日期：2008-11-19 00:00:00

abstract：:Elevations of cytosolic free Ca2+ concentration ([Ca2+]i) induced by addition of ATP have been compared in rat dorsal horn neurones in slices and after their isolation. ATP application induced in neurones in situ a rise of [Ca2+]i by 201 +/- 12 nM. In Ca2+-free external solution the rise was 156 +/- 14 nM (n = 45 of 7...

journal_title：Neuroreport

authors： Kruglikov I,Shutov L,Potapenko E,Voitenko N,Kostyuk P

更新日期：2001-11-16 00:00:00

abstract：:The mechanism by which IL-1 beta exerts its actions in the brain during systemic inflammation is not fully understood, as neither IL-1 receptor gene expression nor IL-1 binding have been identified in significant levels in key areas that respond to IL-1 beta. Having hypothesized that perivascular nitric oxide (NO) mig...

journal_title：Neuroreport

authors： Wong ML,Bongiorno PB,al-Shekhlee A,Esposito A,Khatri P,Licinio J

更新日期：1996-11-04 00:00:00

abstract：:Transcription factors have been used as neuronal markers in the nucleus accumbens (ACB) of male juvenile spontaneously hypertensive rats (SHR), an animal model of attention-deficit hyperactivity disorder (ADHD), to trace putative neural substrates. In SHR, immunocytochemistry and PC-assisted image analysis showed lowe...

journal_title：Neuroreport

authors： Papa M,Sergeant JA,Sadile AG

更新日期：1997-05-06 00:00:00

abstract：:We investigated the correlation of hippocampal volume with homocysteine, folate, vitamin B12 and B6 in alcoholic patients and healthy controls applying a Kohonen feature map (KFM) and conventional statistics. Representation of subjects on the KFM suggested an inverse correlation of hippocampal volume with blood levels...

journal_title：Neuroreport

authors： Kurth C,Wegerer V,Reulbach U,Lewczuk P,Kornhuber J,Steinhoff BJ,Bleich S

更新日期：2004-02-09 00:00:00

abstract：:Human short-latency cortical responses to median nerve stimulation were investigated with a new high resolution electroencephalography technology that markedly enhanced spatial details of somatosensory-evoked potentials (SEPs). Maximum amplitude potentials were estimated over contralateral and/or frontal-mesial scalp ...

journal_title：Neuroreport

authors： Urbano A,Babiloni F,Babiloni C,Ambrosini A,Onorati P,Rossini PM

更新日期：1997-10-20 00:00:00

abstract：:Muller glial cells of the sensory retina mediate K+ and water fluxes that are facilitated by aquaporin-4 (AQP4) water channels and by Kir4.1-K+ channels. However, it is not known which subtypes of aquaporins are expressed in the mammalian retina. Using RT-PCR, we found that both human and rat retinas express mRNA for ...

journal_title：Neuroreport

authors： Tenckhoff S,Hollborn M,Kohen L,Wolf S,Wiedemann P,Bringmann A

更新日期：2005-01-19 00:00:00

abstract：:Propofol is widely used for induction and maintenance of anaesthesia, which causes a rapid loss of consciousness. So far the mechanisms underlying the effect of propofol are still largely unknown. Here, we found that microinjection of propofol in the lateral hypothalamus caused a significant decrease in wakefulness an...

journal_title：Neuroreport

authors： Shi Y,Xiao D,Dai L,Si Y,Fang Q,Wei X

更新日期：2019-10-09 00:00:00

abstract：:Depression is present in a large proportion of patients suffering from chronic pain, and yet the underlying mechanisms remain to be elucidated. Neuroligins (NLs), as a family of cell-adhesion proteins, are involved in synaptic formation and have been linked to various neuropsychiatric disorders. Here, we studied the a...

journal_title：Neuroreport

authors： Pan W,Zhang GF,Li HH,Ji MH,Zhou ZQ,Li KY,Yang JJ

更新日期：2018-07-04 00:00:00

abstract：:The present study examined species differences in spatial and non-spatial memory in the Morris water maze. Male Wistar rats and C57BL/6 mice were tested in a one-day water maze task in which spatial learning, retention, and non-spatial learning were assessed within 3 h. Rats and mice appeared to use different strategi...

journal_title：Neuroreport

authors： Frick KM,Stillner ET,Berger-Sweeney J

更新日期：2000-11-09 00:00:00

abstract：:We studied the neural activation associated with the expectancy of emotional stimuli using whole brain fMRI. Fifteen healthy subjects underwent fMRI scanning during which they performed a warned reaction task using emotional pictures carrying pleasant, unpleasant, or neutral content. The task involved an expected or u...

journal_title：Neuroreport

authors： Ueda K,Okamoto Y,Okada G,Yamashita H,Hori T,Yamawaki S

更新日期：2003-01-20 00:00:00

abstract：:This study was undertaken to establish a method for the culture of organotypic spinal cord slices. A long-term organotypic spinal cord slice culture was conducted from postnatal rats. Lumbar spinal cord was isolated, and meninges were removed from the spinal cord. The spinal cord was embedded in 4% agarose, and was se...

journal_title：Neuroreport

authors： Liu JJ,Huang YJ,Xiang L,Zhao F,Huang SL

更新日期：2017-11-08 00:00:00

abstract：:We recently reported behavioral improvements following intrastriatal transplantation of cryopreserved cultured human neuroteratocarcinoma-derived cells (hNT neurons) in rats with cerebral ischemia induced by occlusion of the middle cerebral artery. In the present study, the viability and survival of hNT neurons were e...

journal_title：Neuroreport

authors： Borlongan CV,Saporta S,Poulos SG,Othberg A,Sanberg PR

更新日期：1998-08-24 00:00:00

abstract：:This study compared the visuospatial asymmetries in children with dyslexia and healthy children by using the manual line bisection task, and investigated the processing of spatial context with a 'local' cueing paradigm consisting of geometric symbols placed on the extremities of the lines. The performance between heal...

journal_title：Neuroreport

authors： Michel C,Bidot S,Bonnetblanc F,Quercia P

更新日期：2011-01-26 00:00:00

abstract：:In adults, neural networks for phonological processing distinct from those involved in acoustical processing are located in the left temporal lobe. We now report that by the age of 3 months, infants display phonological processing devices analogous to those found in adults. Within a stream of identical syllables, acou...

journal_title：Neuroreport

authors： Dehaene-Lambertz G,Baillet S

更新日期：1998-06-01 00:00:00

abstract：:It has been reported that neurons in the amygdala respond to visual cues that predict reward and aversive outcomes. However, it remains unclear whether the representation of reinforcement in the amygdala depends on the relative preference for an outcome compared with another simultaneously available outcome. In this s...

journal_title：Neuroreport

authors： Hirai D,Hosokawa T,Inoue M,Miyachi S,Mikami A

更新日期：2009-04-22 00:00:00

abstract：:In several central nervous system neuronal populations, axotomy triggers the upregulation of regeneration-associated genes such as c-Jun, which determines neurons ability to regenerate axon in a growth-permissive environment. We analyzed the expression of c-Jun in rat ventral medullary neurons after cervical hemisecti...

journal_title：Neuroreport

authors： Vinit S,Boulenguez P,Efthimiadi L,Stamegna JC,Gauthier P,Kastner A

更新日期：2005-09-28 00:00:00

abstract：:Amyloid plaques and neurofibrillary tangles are the major pathological hallmarks of Alzheimer's disease. Neurofibrillary tangles are composed of filaments and paired helical filaments containing polymerized hyperphosphorylated tau protein. Derlin proteins are a family of proteins that are conserved in all eukaryotes, ...

journal_title：Neuroreport

authors： Honjo Y,Ito H,Horibe T,Shimada H,Nakanishi A,Mori H,Takahashi R,Kawakami K

更新日期：2012-07-11 00:00:00

abstract：:Adeno-associated virus type2 (AAV-2) binds to heparan-sulfate proteoglycans on the cell surface. In vivo, attachment of viral particles to cells adjacent to the injection tract limits the distribution of AAV-2 when infused into the CNS parenchyma and heparin co-infusion might decrease the binding of AAV-2 particles to...

journal_title：Neuroreport

authors： Nguyen JB,Sanchez-Pernaute R,Cunningham J,Bankiewicz KS

更新日期：2001-07-03 00:00:00

abstract：:N-CAM-deficient mice display anatomical and electrophysiological abnormalities in the CNS and behavioral deficits. Here, we address the question whether information processing is altered in these mice by analysis of the expression of c-fos and arg 3.1/arc in N-CAM-deficient mice after presentation of saccharin as nove...

journal_title：Neuroreport

authors： Montag-Sallaz M,Montag D,Schachner M

更新日期：2003-07-18 00:00:00

abstract：:Recently, there has been growing interest in the neurobiological role of some amygdalar neuromediators, such as GABA and orexins (ORX), that are responsible for stressful behaviors. Infusion of the major fear-related and panic-related basolateral amygdalar station, the lateral nucleus, with ORX-A and ORX-B, alone or i...

journal_title：Neuroreport

authors： Avolio E,Biasone A,Mele M,Alò R

更新日期：2014-08-20 00:00:00

abstract：:Previous studies have established a role for N-methyl-D-aspartate receptor (NMDAR) containing the GluN2B subunit in efficient learning behavior on a variety of tasks. Recent findings have suggested that NMDAR on GABAergic interneurons may underlie the modulation of striatal function necessary to balance efficient acti...

journal_title：Neuroreport

authors： Brigman JL,Daut RA,Saksida L,Bussey TJ,Nakazawa K,Holmes A

更新日期：2015-06-17 00:00:00

abstract：:The present study assessed the binding characteristics of [125I]angiotensin II to slices of human cerebellum adhered to glass slides using quantitative receptor autoradiography. Specific [125I]angiotensin II binding, defined by the inclusion of unlabelled angiotensin II (1.0 microM), was detected in the molecular laye...

journal_title：Neuroreport

authors： Barnes JM,Barber PC,Barnes NM

更新日期：1991-10-01 00:00:00

abstract：:During the development of central nervous system, radial glial cells support target-specific neuronal migration. We recently reported that after implantation of chitosan channels with complete spinal cord transection, the tissue bridging the spinal cord stumps contained axons and radial glial cells. The purpose of thi...

journal_title：Neuroreport

authors： Nomura H,Kim H,Mothe A,Zahir T,Kulbatski I,Morshead CM,Shoichet MS,Tator CH

更新日期：2010-09-15 00:00:00

abstract：:Interleukin-6 (IL-6) is a neurotrophic cytokine, however, its direct effect on nerve regeneration has not been well characterized. We therefore examined the effect of IL-6 on neurite regeneration using the rat dorsal root ganglion. IL-6 significantly enhanced neurite regeneration from transected nerve terminals. We al...

journal_title：Neuroreport

authors： Shuto T,Horie H,Hikawa N,Sango K,Tokashiki A,Murata H,Yamamoto I,Ishikawa Y

更新日期：2001-04-17 00:00:00