Abstract:
:In several central nervous system neuronal populations, axotomy triggers the upregulation of regeneration-associated genes such as c-Jun, which determines neurons ability to regenerate axon in a growth-permissive environment. We analyzed the expression of c-Jun in rat ventral medullary neurons after cervical hemisection in order to investigate their intrinsic regenerative potential. Maximal expression of c-Jun was observed 7 days after injury mainly in axotomized medullary neurons located in the gigantocellularis nucleus, the raphe nucleus and, although less intensively, in the rostral ventral respiratory group. This suggests that after high cervical injury, a large number of medullary neurons projecting to the spinal cord become competent for axonal regeneration, although this regenerating potential may not be equivalent between the various neuronal populations.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Vinit S,Boulenguez P,Efthimiadi L,Stamegna JC,Gauthier P,Kastner Adoi
10.1097/01.wnr.0000179075.32035.0fsubject
Has Abstractpub_date
2005-09-28 00:00:00pages
1535-9issue
14eissn
0959-4965issn
1473-558Xpii
00001756-200509280-00001journal_volume
16pub_type
杂志文章相关文献
NEUROREPORT文献大全abstract::Complex tones such as vowels expressed by the human voice vary both in fundamental pitch (harmonic periodicity) and spectrum shape (vowel type). Three different pitches and spectra were combined into nine auditory stimuli. Latencies of cerebral evoked potential components decreased significantly as pitch increased, wh...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199603220-00014
更新日期:1996-03-22 00:00:00
abstract:OBJECTIVE:The current study aims to investigate whether computer generated (CG) expressions of emotion evoke similar emotional appraisal processing in the lateral orbitofrontal cortex (lOFC) compared to real human expressions, as well as how speech cues would influence the processing. METHODS:Functional near-infrared ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001420
更新日期:2020-04-08 00:00:00
abstract::Auditory sensory memory is assumed to play an important role in cognitive development, but little is known about it in young children. The aim of this study was to estimate the duration of auditory sensory memory in 2-year-old children. We recorded the mismatch negativity in response to tone stimuli presented with dif...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3282f97867
更新日期:2008-03-26 00:00:00
abstract::Injury and diseases of the nervous system can induce astrocytes to form tenacious glial scars. We induced focal cortical freeze-lesions in neonatal rats and examined scars histologically and electrophysiologically in tissue slices isolated 2-3 weeks after lesioning. Lesions displayed marked gliosis, characterized by u...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200009280-00022
更新日期:2000-09-28 00:00:00
abstract::Clinical and experimental studies clearly demonstrate that prolonged seizures and status epilepticus induce neuronal cell death in the brain. Recent evidence suggests that induction of apoptosis contributes greatly to seizure-induced brain damage. We recently demonstrated that intrahippocampal delivery of botulinum ne...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32801b3cbb
更新日期:2007-04-16 00:00:00
abstract::Increased oxidative stress in the brain due to chronic ethanol consumption is known to result in a number of neurodegenerative changes. This study was designed to test whether dietary supplementation of grape polyphenols (GP) can offer protection to the neurodegenerative changes resulting from chronic ethanol consumpt...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199901180-00018
更新日期:1999-01-18 00:00:00
abstract::Although decision-making is typically seen as a rational process, emotions play a role in tasks that include unfairness. Recently, activation in the right dorsolateral prefrontal cortex during offers experienced as unfair in the Ultimatum Game was suggested to subserve goal maintenance in this task. This is restricted...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000183907.08149.14
更新日期:2005-11-07 00:00:00
abstract::We investigated the roles of the auditory cortex in discrimination learning of vowel-like sounds consisting of multiple formants. Rats were trained to discriminate between synthetic sounds with four formants. Bilateral electrolytic lesions including the primary auditory cortex and the dorsal auditory association corte...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32800fef9d
更新日期:2006-11-27 00:00:00
abstract::The study aimed to investigate the time-course of electromagnetic field (EMF)-induced effects on human cognitive and behavioral performance and on tympanic temperature. Subjects were randomly assigned to two groups, exposed to a 902.40 MHz EMF before the testing session, or to the same signal during the data collectin...
journal_title:Neuroreport
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00001756-200401190-00031
更新日期:2004-01-19 00:00:00
abstract::By means of magnetoencephalography we investigated the auditory-evoked fields (AEFs) elicited by broadband noise bursts in a gap-detection paradigm in children. AEFs of 16 healthy children (mean age 8.7 years) were recorded while they passively listened to 100-ms white-noise bursts with temporal gaps of 3, 6, 10 and 3...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3282f0b6e2
更新日期:2007-10-29 00:00:00
abstract::Sciatic nerve resection leaving a 15 mm gap could not be repaired by bridging the stumps with a silicone tube prefilled with a laminin gel. However, when purified olfactory ensheathing cells (EC) were added to the gel filling the tube, successful axonal regeneration was observed in 50% of rats. With 12 mm gaps, regene...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199904060-00035
更新日期:1999-04-06 00:00:00
abstract::To analyze an auditory scene, the segregation of the input into separate streams of information is necessary. Here, the mismatch negativity (MMN) of the event-related potential was used to trace the number of simultaneously monitored streams in auditory scene analysis. Subjects passively listened to sounds belonging t...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200305060-00019
更新日期:2003-05-06 00:00:00
abstract::We have studied the distribution of mGluR2/3 in the mouse superior colliculus (SC) with antibody immunocytochemistry and the effect of enucleation on this distribution. We also compared this labeling to that for calbindin D28K. Anti-mGluR2/3-immunoreactive (IR) cells formed distinctive laminar patterns within the lowe...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199904260-00034
更新日期:1999-04-26 00:00:00
abstract::There has been intense interest in determining how the visual brain processes the outside world, and in identifying the neuroanatomical correlates of the ability to create art. Comparing art production before and after illness onset permits some speculation on the function of selective brain regions affected by the ne...
journal_title:Neuroreport
pub_type: 杂志文章,评审
doi:10.1097/00001756-200404290-00001
更新日期:2004-04-29 00:00:00
abstract::The neurotrophin-inducible gene VGF plays an important role in the maintenance of organismal energy balance and in the mediation of hippocampal synaptic activity. The regulatory mechanism of VGF transcription is not fully understood. The neuron-restrictive silencer factor (NRSF) binds with the neuron-restrictive silen...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000316
更新日期:2015-02-11 00:00:00
abstract::Models of corticostriatal motor circuitry have focused on the role of the circuit in the hemisphere of the motor cortex providing primary control (contralateral to the movement). We used functional magnetic resonance imaging and functional connectivity analyses to study circuit function in both the controlling and non...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328302c873
更新日期:2008-06-11 00:00:00
abstract::This study investigated whether mild birth complications (C-section birth, C-section + 15 min global anoxia) interact with stress at adulthood to modulate levels of [3H]WIN 35428 binding to dopamine transporters (DAT) in rat brain. Without stress, adult C-sectioned rats showed increased DAT binding in the dorsal stria...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200202110-00006
更新日期:2002-02-11 00:00:00
abstract::Hypoxic-ischemic brain damage (HIBD) occurs due to intrauterine hypoxia ischemia influencing the energy supply for fetal brain cells, which affects the metabolism of the brain to make the brain suffer a severe damage. Erythropoietin (EPO), which regulates hemacytopoiesis, is a kind of cytokine. EPO is sensitive to hyp...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001194
更新日期:2019-03-06 00:00:00
abstract::Event-related potential studies have reported error-related negativity following both error commission and feedback indicating errors or monetary loss. The present study examined whether error-related negativities could be elicited by a predictive cue presented prior to both the decision and subsequent feedback in a g...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3282f0d50b
更新日期:2007-11-19 00:00:00
abstract::The 29 amino acid neuropeptide galanin is normally expressed in < 5% of sensory neurons in the adult dorsal root ganglia. After nerve transection (axotomy), the galanin content of the dorsal root ganglia rises 120-fold and the peptide is then expressed in > 50% of neurons. Published data suggest that galanin plays a r...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200211150-00028
更新日期:2002-11-15 00:00:00
abstract::Prior research with rodent models, performed predominantly in males, has demonstrated a significant association between focal neocortical malformations (e.g. ectopias and microgyria) and rate-specific auditory processing deficits. In the current study and consistent with prior findings, we report that ectopic male BXS...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200212030-00021
更新日期:2002-12-03 00:00:00
abstract::Menthol is known as an agonist for cold-sensitive transient receptor potential channels (TRPM8) and also as a direct modulator of GABA channels. We examined the effects of menthol on respiratory rhythm generation in the brainstem-spinal cord preparations isolated from newborn rats. Menthol decreased respiratory rhythm...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283405bad
更新日期:2010-12-08 00:00:00
abstract::The alpha 2-macroglobulin receptor/low-density lipoprotein receptor-related protein (alpha 2-M-R/LRP) is a multifunctional receptor which has been implicated in lipoprotein metabolism, clearance of proteinase-proteinase inhibitor complexes and regulation of growth factor/cytokine metabolism. This receptor is abundantl...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199612200-00030
更新日期:1996-12-20 00:00:00
abstract::The possible role of endogenous cholinergic innervation in hippocampal plasticity is controversial. We studied the role of acetylcholine (ACh) in short- and long-term potentiation (STP and LTP), using the cholinergic neurotoxin 192 IgG-saporin. It was still possible to induce STP the LTP in the CA1 field following com...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199603220-00024
更新日期:1996-03-22 00:00:00
abstract::Newly hatched domestic chicks serve as an important model for experimental studies of neural and behavioral plasticity. Brain-derived neurotrophic factor (BDNF) has been shown to play a critical role in synaptic plasticity, including long-term potentiation, which underlies learning and memory in rodents. Here we show ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32834d0be7
更新日期:2011-12-07 00:00:00
abstract::Plasticity in the central nervous system may play an important role in clinical pain. The present study shows that long-term potentiation (LTP) may be induced in single wide dynamic range (WDR) neurons in the dorsal horn after high-frequency stimulation of the sciatic nerve in intact urethane anaesthetized rats. Extra...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199711100-00002
更新日期:1997-11-10 00:00:00
abstract::A combined microdialysis/microinfusion technique was used to investigate whether arginine vasopressin (AVP) is involved in the regulation of its own release into the extracellular fluid of the supraoptic nucleus in vivo. While intranuclear neuropeptide release was monitored, 0.33 microliter of either vehicle, lysine v...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199406020-00005
更新日期:1994-06-02 00:00:00
abstract::While effects of attention on late and middle latency components of the evoked potential have been demonstrated, similar effects on brain stem evoked potentials--in particular on the human frequency-following potential (FFP)--are controversial. The FFP is a response to tone bursts in the frequency range of human langu...
journal_title:Neuroreport
pub_type: 临床试验,杂志文章
doi:10.1097/00001756-199408150-00017
更新日期:1994-08-15 00:00:00
abstract::Distracted driving remains a leading factor in fatal motor vehicle crashes, particularly in young drivers. Due to ongoing neuromaturation, attention capabilities are changing and improving throughout young adulthood. Here, we sought to bridge neuroscience with driving simulation by evaluating the effects of driving on...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001451
更新日期:2020-05-22 00:00:00
abstract::Transcranial direct current stimulation (tDCS) was used in 17 normal individuals to modulate vestibulo-ocular reflex (VOR) and self-motion perception rotational thresholds. The electrodes were applied over the temporoparietal junction bilaterally. Both vestibular nystagmic and perceptual thresholds were increased duri...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283646e65
更新日期:2013-10-02 00:00:00