Grape polyphenols protect neurodegenerative changes induced by chronic ethanol administration.

abstract：:The function of the lateral part of the human cerebellum was investigated through cerebro-cerebellar functional connectivity. We propose a laterality index method to reveal a functional and possibly anatomical pathway between the cerebral cortex and the cerebellum. The brain activity involved in learning a visually-gu...

journal_title：Neuroreport

authors： Tamada T,Miyauchi S,Imamizu H,Yoshioka T,Kawato M

更新日期：1999-02-05 00:00:00

abstract：:The time course of responses to repeated presentations of affective stimuli is well characterized in healthy individuals but remains to be characterized in patients with bipolar disorder. Using functional magnetic resonance imaging, we compared early-stage and late-stage brain activation during a two-block fearful fac...

journal_title：Neuroreport

authors： Killgore WD,Gruber SA,Yurgelun-Todd DA

更新日期：2008-10-08 00:00:00

abstract：:There has been intense interest in determining how the visual brain processes the outside world, and in identifying the neuroanatomical correlates of the ability to create art. Comparing art production before and after illness onset permits some speculation on the function of selective brain regions affected by the ne...

journal_title：Neuroreport

authors： Kleiner-Fisman G,Lang AE

更新日期：2004-04-29 00:00:00

abstract：:Epilepsy is a neurological disorder with recurrent unprovoked seizures as the main symptom. Of the coumarin derivatives in Angelica gigas, decursin, a major coumarin component, was reported to exhibit significant protective activity against glutamate-induced neurotoxicity when added to primary cultures of rat cortical...

journal_title：Neuroreport

authors： Lee JK,Jeong JW,Jang T,Lee GW,Han H,Kang JS,Kim IH

更新日期：2014-11-12 00:00:00

abstract：:Optic nerves of adult rats were crushed 2 mm behind the eye to examine the ability of retinal ganglion cells (RGCs) to regenerate their axons. Some animals were treated with the immunophilin ligands FK 506 or GPI 1046 for up to 4 weeks. After 10 days to 16 months, regenerating RGC axons were visualized using anterogra...

journal_title：Neuroreport

authors： Campbell G,Holt JK,Shotton HR,Anderson PN,Bavetta S,Lieberman AR

更新日期：1999-12-16 00:00:00

abstract：:Ts65DN mice were developed as a model of Down syndrome (DS); they are trisomic for the distal segment of chromosome 16 (MMU16), which contains genes syntenic with some of the genes located on the critical region of human chromosome 21 (HSA21). Since behavioral and neurochemical disturbances have been observed in this ...

journal_title：Neuroreport

authors： Megías M,Verduga R,Dierssen M,Flórez J,Insausti R,Crespo D

更新日期：1997-11-10 00:00:00

abstract：:Recently it has been reported that a missense G(88)C mutation within exon 3 and a missense G(209)A mutation within exon 4 of the alpha-synuclein gene were linked to familial Parkinson's Disease (PD). We decided to investigate if these and any other mutations in exons 3 and 4 of the alpha-synuclein gene could be detect...

journal_title：Neuroreport

authors： El-Agnaf OM,Curran MD,Wallace A,Middleton D,Murgatroyd C,Curtis A,Perry R,Jaros E

更新日期：1998-12-01 00:00:00

abstract：:We have previously suggested that progranulin mediates the stimulatory effects of estrogen on adult neurogenesis in the hippocampus. Neurogenesis in mature animals is enhanced by growth factors, environmental enrichment, and voluntary exercise. In this study, we investigated the role of progranulin in voluntary runnin...

journal_title：Neuroreport

authors： Asakura R,Matsuwaki T,Shim JH,Yamanouchi K,Nishihara M

更新日期：2011-12-07 00:00:00

abstract：:We used an electrophysiological marker of linguistic discordance, the N400 wave, to investigate how linguistic and pseudo-linguistic stimuli are categorised during sleep as compared to waking. During wakefulness, signs of discordance detection were, as expected, greater for pseudo-words than for real but semantically ...

journal_title：Neuroreport

authors： Perrin F,Bastuji H,Garcia-Larrea L

更新日期：2002-07-19 00:00:00

abstract：:Activation of mu-opioid receptors is critical to steroid regulation of female sexual behavior, lordosis, in rodents. Estrogen treatment activates mu-opioid receptors in the medial preoptic area inhibiting lordosis, but ultimately appears important for progesterone facilitation of lordosis. We investigated the role of ...

journal_title：Neuroreport

authors： Sinchak K,Shahedi K,Dewing P,Micevych P

更新日期：2005-10-17 00:00:00

abstract：:Cortical auditory categorization was assessed in 2-month-old infants at genetic risk for dyslexia and controls. Manipulated /bAk/ and /dAk/ speech stimuli were used as frequently presented standards. The neuroelectric brain responses of the control infants were highly sensitive to the phoneme boundary that separated t...

journal_title：Neuroreport

authors： van Leeuwen T,Been P,van Herten M,Zwarts F,Maassen B,van der Leij A

更新日期：2007-06-11 00:00:00

abstract：:Neuroblastoma is an important problem in children. Long noncoding RNAs (lncRNAs) exhibit important roles in tumorigenicity of neuroblastoma. However, the role and mechanism of lncRNA small nucleolar RNA host gene 16 (SNHG16) in neuroblastoma tumorigenicity remain poorly understood. Forty-six neuroblastoma samples and ...

journal_title：Neuroreport

authors： Ge Y,Tan S,Bi J,Rao M,Yu Y,Tian L

更新日期：2020-12-09 00:00:00

abstract：:We have previously reported that antidepressants such as desipramine (DMI) induce axonal regeneration of brain noradrenergic neurons. In the present experiments, the role of phospholipase A2 (PLA2) in the regeneration of brain noradrenergic axons was studied. Symmetrical sites of the rat frontal cortex were pretreated...

journal_title：Neuroreport

authors： Nakamura S

更新日期：1993-04-01 00:00:00

abstract：:Satiety signals from the gastrointestinal tract travel via vagal afferents to the nucleus of the solitary tract (NTS) in the brain stem, the first central relay in a neural network which controls food intake. The non-competitive NMDA antagonist MK-801 facilitates food intake in rats by acting on the NTS. Here we repor...

journal_title：Neuroreport

authors： Qian M,Zhu SW,Johnson AE,Södersten P

更新日期：2000-08-21 00:00:00

abstract：:We demonstrate the use of magnetic resonance imaging (MRI) for detection of neurotransmitter stimulation using the dopamine transporter ligands amphetamine and CFT (2beta-carbomethoxy-3beta-(4-fluorophenyl)tropane) as pharmacological challenges. We demonstrate that the unilateral loss of a hemodynamic response to eith...

journal_title：Neuroreport

authors： Chen YI,Brownell AL,Galpern W,Isacson O,Bogdanov M,Beal MF,Livni E,Rosen BR,Jenkins BG

更新日期：1999-09-29 00:00:00

abstract：:We examined the electrophysiological correlates of the processing of social exclusion and inclusion by using a modified version of the Cyberball paradigm. Exclusion was found to be associated with a significant increase in the P3 complex. The frontal-central P3a was primarily related to the affective processing of rej...

journal_title：Neuroreport

authors： Gutz L,Küpper C,Renneberg B,Niedeggen M

更新日期：2011-06-22 00:00:00

abstract：:Secondary brain injury imposes great effects on the prognosis of patients following traumatic brain injury (TBI). Accumulating evidence suggests that nuclear factor erythroid 2-related factor 2 (Nrf2) could play a neuroprotective role in experimental TBI models by regulating the expression of numerous antioxidant, ant...

journal_title：Neuroreport

authors： He Y,Yan H,Ni H,Liang W,Jin W

更新日期：2019-03-20 00:00:00

abstract：:To assess the effect of genetic factors on sporadic Parkinson disease, we performed a case-control study of a variant (G2385R) in Leucine-Rich Repeat kinase 2 among the Japanese population. The G2385R (c.7153G>A) variant was reported as a risk factor for sporadic Parkinson disease in the Chinese population from Taiwan...

journal_title：Neuroreport

authors： Funayama M,Li Y,Tomiyama H,Yoshino H,Imamichi Y,Yamamoto M,Murata M,Toda T,Mizuno Y,Hattori N

更新日期：2007-02-12 00:00:00

abstract：:Neurofibromin, the product of the neurofibromatosis 1 (NF1) gene, is an important tumor suppressor protein expressed most abundantly in the nervous system. Within the central nervous system, neurofibromin has been localized to neurons and oligodendrocytes but not astrocytes. As individuals with NF1 are at an increased...

journal_title：Neuroreport

authors： Hewett SJ,Choi DW,Gutmann DH

更新日期：1995-07-31 00:00:00

abstract：:In order to investigate GABA uptake into Müller glial cells electrophysiologically, we used the whole-cell voltage-clamp technique. Since Müller cells were insensitive to application of muscimol and baclofen, the expression of GABAA and GABAB receptors can be excluded. Therefore, the observed GABA current must be due ...

journal_title：Neuroreport

authors： Biedermann B,Eberhardt W,Reichelt W

更新日期：1994-01-12 00:00:00

abstract：:The increase in neural activity in cat visual cortex associated with eye movements has been thought to reflect a replica of the motor command signal. We examined the timing of the saccade-related increase in neural activity in cat areas 17 and 18 in relation to saccade onset and offset. The increase in activity was te...

journal_title：Neuroreport

authors： Park J,Lee C

更新日期：2000-06-05 00:00:00

abstract：:Neurotrophins are promising candidates to slow the progression of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease in which spinal and cortical motoneurons selectively degenerate. In a long-term in vitro model, malonate-induced toxicity and cell death of motoneurons have been demonstrated. Here we stud...

journal_title：Neuroreport

authors： Van Westerlaak MG,Bär PR,Cools AR,Joosten EA

更新日期：2001-05-25 00:00:00

abstract：:We examined covert and overt orienting in response to non-predictive gaze direction cues and investigated whether the subcortical superior colliculus (SC) plays a role in this type of orienting. Participants viewed a centrally presented gazing schematic face and responded to targets appearing at gazed-at or non-gazed-...

journal_title：Neuroreport

authors： Friesen CK,Kingstone A

更新日期：2003-03-03 00:00:00

abstract：:In rapid serial visual presentation of pictures, an early event-related brain potential component shows enlarged negativity over occipital regions for emotional pictures compared with neutral pictures. The present study examined whether the processing of emotional target pictures varies as a function of stimulus repet...

journal_title：Neuroreport

authors： Schupp HT,Stockburger J,Codispoti M,Junghöfer M,Weike AI,Hamm AO

更新日期：2006-03-20 00:00:00

abstract：:Extracellular recordings from neurosecretory cells in the hypothalamic paraventricular nucleus (PVN) displayed either an excitation or no response following electrical stimulation (5 Hz) of the A1 noradrenergic region of the ventrolateral medulla, and exhibited either an increase or no effect in neuronal activity in r...

journal_title：Neuroreport

authors： Tanaka J,Nomura M,Saito H

更新日期：1992-03-01 00:00:00

abstract：:Activity of calpains and caspase-3 inferred from proteolysis of the cytoskeletal protein alpha-spectrin into signature spectrin breakdown products (SBDPs) was used to provide the first systematic and simultaneous comparison of changes in activity of these two families of cysteine proteases after traumatic brain injury...

journal_title：Neuroreport

authors： Pike BR,Zhao X,Newcomb JK,Posmantur RM,Wang KK,Hayes RL

更新日期：1998-08-03 00:00:00

abstract：:Low doses of estrogen (E) were given to ovariectomized (OVX) rats and the ventromedial hypothalamic nucleus (VMN) was examined at the ultrastructural level. Administration of 10 micrograms of E for two consecutive days resulted in an increase in the number of axodendritic synapses in the VMN in comparison to OVX rats ...

journal_title：Neuroreport

authors： Frankfurt M,McEwen BS

更新日期：1991-07-01 00:00:00

abstract：:Increasing evidence suggests a neurotransmitter role for NO in the mammalian CNS. We have now studied the behavioural and electrocortical (ECoG) profile of rats injected into the lateral cerebral ventricle (ICV) with L-arginine (L-arg), the endogenous donor of the guanidino group from which NO physiologically originat...

journal_title：Neuroreport

authors： Mollace V,Bagetta G,Nisticò G

更新日期：1991-05-01 00:00:00

abstract：:To achieve neuronal differentiation of mouse bone mesenchymal stem cells (bMSCs) into neuron-like cells and explore the role of miR-122-5p that may regulate T-box brain 1 (Tbr1) expression during the induction. BMSCs were cultured and induced with butylated hydroxyanisole, retinoic acid (RA), basic fibroblast growth f...

journal_title：Neuroreport

authors： Yang Y,Shen Z,Sun W,Gao S,Li Y,Guo Y

更新日期：2017-05-03 00:00:00

abstract：:Deficits of working memory (WM) are recognized as an important pathological feature in schizophrenia. Since the P600 component of event related potentials has been hypothesized that represents aspects of second-pass parsing processes of information processing, and is related to WM, the present study focuses on P600 el...

journal_title：Neuroreport

authors： Papageorgiou C,Kontaxakis VP,Havaki-Kontaxaki BJ,Stamouli S,Vasios C,Asvestas P,Matsopoulos GK,Kontopantelis E,Rabavilas A,Uzunoglu N,Christodoulou GN

更新日期：2001-09-17 00:00:00