The role of miR-122-5p in negatively regulating T-box brain 1 expression on the differentiation of mouse bone mesenchymal stem cells.

abstract：:Satiety signals from the gastrointestinal tract travel via vagal afferents to the nucleus of the solitary tract (NTS) in the brain stem, the first central relay in a neural network which controls food intake. The non-competitive NMDA antagonist MK-801 facilitates food intake in rats by acting on the NTS. Here we repor...

journal_title：Neuroreport

authors： Qian M,Zhu SW,Johnson AE,Södersten P

更新日期：2000-08-21 00:00:00

abstract：:Elevations of cytosolic free Ca2+ concentration ([Ca2+]i) induced by addition of ATP have been compared in rat dorsal horn neurones in slices and after their isolation. ATP application induced in neurones in situ a rise of [Ca2+]i by 201 +/- 12 nM. In Ca2+-free external solution the rise was 156 +/- 14 nM (n = 45 of 7...

journal_title：Neuroreport

authors： Kruglikov I,Shutov L,Potapenko E,Voitenko N,Kostyuk P

更新日期：2001-11-16 00:00:00

abstract：:Adult rats were studied for serotonin and its metabolite in basal ganglia, nociceptive responses to electric current and tremor induced by 5-methoxy-N,N-dimethyltryptamine (5-MeODMT) to assess the effects of a single systemic injection of serotonin antiserum given at 1 day old. Antiserum-treated animals showed no over...

journal_title：Neuroreport

authors： Mohanakumar KP,Mohanty S,Ganguly DK

更新日期：1995-12-29 00:00:00

abstract：:Recent studies have demonstrated a loss of cannabinoid CB1 receptors in the basal ganglia in Huntington's disease (HD), but there are no data on endocannabinoid levels in this disease. In the present study, we have addressed this question by using rats with bilateral intrastriatal injections of 3-nitropropionic acid (...

journal_title：Neuroreport

authors： Lastres-Becker I,Fezza F,Cebeira M,Bisogno T,Ramos JA,Milone A,Fernández-Ruiz J,Di Marzo V

更新日期：2001-07-20 00:00:00

abstract：:We investigated the brain mechanisms enabling one automatically discriminate phoneme category irrespective of the large inter-speaker variability in the acoustic features of the voices. For this purpose, subjects were presented with 450 different speech stimuli, each uttered by a different speaker, belonging to three ...

journal_title：Neuroreport

authors： Shestakova A,Brattico E,Huotilainen M,Galunov V,Soloviev A,Sams M,Ilmoniemi RJ,Näätänen R

更新日期：2002-10-07 00:00:00

abstract：:Ca2+/calmodulin-dependent protein kinase II (CaMKII) plays critical roles in neurotransmission, synaptic plasticity, learning and memory. The aim of this study was to examine, by in situ hybridization, prefrontal cortical expression of CaMKII alpha mRNA in postmortem brains of unipolar, bipolar, schizophrenic, and con...

journal_title：Neuroreport

authors： Xing G,Russell S,Hough C,O'Grady J,Zhang L,Yang S,Zhang LX,Post R

更新日期：2002-03-25 00:00:00

abstract：:Deficits in auditory sensory memory at the electrophysiological level as indexed by mismatch negativity and those in auditory verbal memory at the neuropsychological level have been independently demonstrated in previous studies of schizophrenia. We predicted a specific association between these indices in schizophren...

journal_title：Neuroreport

authors： Kawakubo Y,Kasai K,Kudo N,Rogers MA,Nakagome K,Itoh K,Kato N

更新日期：2006-07-17 00:00:00

abstract：:The effect of Co-dergocrine (Hydergine) on acetylcholine (ACh) release in the striatum and hippocampus has been studied by means of brain microdialysis and compared to the effect of SKF 38393 and of LY 171555 selective D1 and D2 dopamine (DA) receptor agonists, respectively. Co-dergocrine (1 and 5 mg kg-1 i.p.) as wel...

journal_title：Neuroreport

authors： Imperato A,Obinu MC,Dazzi L,Carta G,Mascia MS,Casu MA,Gessa GL

更新日期：1994-02-24 00:00:00

abstract：:One problem in motor control concerns the mechanism whereby the central nervous system translates the motor cortical command encoded in cell activity into a coordinated contraction of limb muscles to generate a desired motor output. This problem is closely related to the design of adaptive systems that transform neuro...

journal_title：Neuroreport

authors： Lukashin AV,Amirikian BR,Georgopoulos AP

更新日期：1996-11-04 00:00:00

abstract：:Nicotine injected in the supraoptic nucleus facilitates vasopressin release from the neurohypophysis. Nicotinic acetylcholine receptors have been found not only on vasopressin-producing cell bodies but also on presynaptic nerve terminals in the nucleus. Vasopressin cells receive excitatory synaptic inputs from noradre...

journal_title：Neuroreport

authors： Liu X,Onaka T,Yagi K

更新日期：2001-03-05 00:00:00

abstract：:Papaverine is a non-specific vasodilatory drug, which was found to unexpectedly cause opening of the blood-brain barrier (BBB). We studied the expression of two endothelial cell related markers, endothelial barrier antigen (EBA) as a marker of BBB intactness, and matrix metalloproteinase-9 (MMP-9), an extracellular ma...

journal_title：Neuroreport

authors： Bhattacharjee AK,Kondoh T,Ikeda M,Kohmura E

更新日期：2002-12-03 00:00:00

abstract：:It is often claimed that binding information across sensory modalities leads to coherent, unitary mental representations. The dramatic illusions experienced as a result of intersensory conflict, such as the McGurk effect, are often attributed to a propensity of the perceptual system to impose multisensory coherence on...

journal_title：Neuroreport

authors： Soto-Faraco S,Alsius A

更新日期：2007-03-05 00:00:00

abstract：:S100B is a calcium binding protein from astrocytes that regulates protein phosphorylation by binding to substrates and protein kinases. S100B might also regulate protein phosphatases and this was investigated for protein phosphatase 2B (calcineurin). The results indicate that S100B (5-10 microM) increased the activity...

journal_title：Neuroreport

authors： Leal RB,Frizzo JK,Tramontina F,Fieuw-Makaroff S,Bobrovskaya L,Dunkley PR,Gonçalves CA

更新日期：2004-02-09 00:00:00

abstract：:The cochlea can be protected from acoustic trauma by moderate-level sound exposure. It is suggested that olivocochlear system may play a significant role in this protection. This study was performed to investigate distortion product otoacoustic emission (DPOAE) amplitudes changes and the efficiency of contralateral no...

journal_title：Neuroreport

authors： Peng JH,Tao ZZ,Huang ZW

更新日期：2007-07-16 00:00:00

abstract：:By means of magnetoencephalography we investigated the auditory-evoked fields (AEFs) elicited by broadband noise bursts in a gap-detection paradigm in children. AEFs of 16 healthy children (mean age 8.7 years) were recorded while they passively listened to 100-ms white-noise bursts with temporal gaps of 3, 6, 10 and 3...

journal_title：Neuroreport

authors： Diedler J,Pietz J,Bast T,Rupp A

更新日期：2007-10-29 00:00:00

abstract：:The effects of copper on voltage-gated A-type potassium currents were investigated in acutely dissociated rat hippocampal CA1 neurons using the whole-cell patch-clamp technique. Extracellular application of various concentrations of copper (1-1000 microM) reversibly reduced the amplitude of voltage-gated A-type potass...

journal_title：Neuroreport

authors： Niu ZD,Yu K,Gu Y,Wang M,She JQ,Chen WH,Ruan DY

更新日期：2005-09-28 00:00:00

abstract：:This study examined the effects of cocaine HCl and ambient temperature on the core body temperature of the rat. To further examine the mechanisms of cocaine-induced changes in temperature regulation, the effects of cocaine on behavioral thermoregulatory responses were also observed. At normal room temperature (20 degr...

journal_title：Neuroreport

authors： Gonzalez LP

更新日期：1993-01-01 00:00:00

abstract：:Adult male hamsters and rats were reared for 2 months in either an isolated condition (IC) or a social condition (SC). The lengths of synaptic active zones (SAZ) of synapses in the granule cell layer of the accessory olfactory bulb were measured as an indicator of synaptic size in perforated and non-perforated synapse...

journal_title：Neuroreport

authors： Matsuoka M,Mori Y,Ichikawa M

更新日期：1996-10-02 00:00:00

abstract：:A two-electrode voltage clamp was used to examine the effects of the local anaesthetics (LAs) lidocaine, tetracaine and bupivacaine, and the meta-isomer of lidocaine (LL33), on the gamma-aminobutyric acid (GABA)-gated Cl- channel in the crayfish stretch receptor neurone. The voltage-induced current changes were record...

journal_title：Neuroreport

authors： Nordmark J,Rydqvist B

更新日期：1997-01-20 00:00:00

abstract：:This study examined the long-term effects of the antidepressant escitalopram on rat serotonin (5-HT) neuronal activity and hippocampal neuroplasticity. In the dorsal raphe nucleus, a 2-week treatment with escitalopram (10 mg/kg/day, subcutaneous) did not modify the firing activity of 5-HT neurons, whereas a cotreatmen...

journal_title：Neuroreport

authors： Mnie-Filali O,Faure C,Mansari ME,Lambás-Señas L,Bérod A,Zimmer L,Sánchez C,Haddjeri N

更新日期：2007-10-08 00:00:00

abstract：:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity reproduces many of the features of Parkinson's disease (PD). alpha-Synuclein has been identified as a prominent component of the Lewy body (LB), the pathological hallmark of PD. MPTP-treated primates have been reported to develop intraneuronal inclusion...

journal_title：Neuroreport

authors： Kowall NW,Hantraye P,Brouillet E,Beal MF,McKee AC,Ferrante RJ

更新日期：2000-01-17 00:00:00

abstract：:The amyloid cascade hypothesis suggests that amyloid precursor protein (APP) proteolytic processing is a key event in the pathogenesis of Alzheimer's disease (AD). The enzymes beta-site APP cleaving enzyme (BACE) and A disintegrin and metalloproteinase 10 (ADAM10) play an important role in APP proteolysis. We measured...

journal_title：Neuroreport

authors： Gatta LB,Albertini A,Ravid R,Finazzi D

更新日期：2002-11-15 00:00:00

abstract：:In previous studies, we demonstrated functional neuronal and dopaminergic differentiation of fetal mesencephalic neural precursor cells. The major factors for orienting their progeny towards a dopaminergic phenotype are forskolin and interleukin-1beta. Here, we investigated the effects of dexamethasone (10 microM) on ...

journal_title：Neuroreport

authors： Sabolek M,Herborg A,Schwarz J,Storch A

更新日期：2006-11-06 00:00:00

abstract：:There is abundant psychophysical evidence in humans suggesting the existence of parallel pathways subserving different aspects of vision. However, there is little direct proof of the neural structures underlying the two pathways. We present direct anatomical evidence that in the normal human optic tract fibres are seg...

journal_title：Neuroreport

authors： Tassinari G,Campara D,Balercia G,Chilosi M,Martignoni G,Marzi CA

更新日期：1994-07-21 00:00:00

abstract：:Music is an essential communication tool that can convey emotional information. Segmentation of a sound stream of music at event boundaries is necessary for identification and extraction of musical context and features. To investigate recognition of music termination structure, or cadence, we composed music sequences ...

journal_title：Neuroreport

authors： Hoshi-Shiba R,Furukawa K,Okanoya K

更新日期：2014-07-09 00:00:00

abstract：:For the majority of neurones in cat striate cortex, the response to an optimal stimulus presented to one eye is suppressed when a stimulus of substantially different orientation is presented to the other eye. In order to determine the true orientational tuning of the underlying inhibitory interactions in the absence o...

journal_title：Neuroreport

authors： Sengpiel F,Freeman TC,Blakemore C

更新日期：1995-11-13 00:00:00

abstract：:Short-term exposure of primary cultures of cerebellar granule cells from neonatal rat brain to high concentrations of glutamate results in neuronal degeneration. We found that glutamate, before causing neuronal degeneration, induced a significant increase of Tau protein immunostaining. Time-course experiments revealed...

journal_title：Neuroreport

authors： Pizzi M,Valerio A,Ribola M,Spano PF,Memo M

更新日期：1993-06-01 00:00:00

abstract：:Piccolo is one of the components of the active zone at chemical synapses and regulates the transport of synaptic vesicles. The piccolo C2A domain is an important calcium sensor and binds with phosphatidylinositol or synaptotagmin-1. Recently, clinical studies suggested that a single nucleotide polymorphism in the picc...

journal_title：Neuroreport

authors： Furukawa-Hibi Y,Nitta A,Fukumitsu H,Somiya H,Furukawa S,Nabeshima T,Yamada K

更新日期：2010-12-29 00:00:00

abstract：:Deficits of working memory (WM) are recognized as an important pathological feature in schizophrenia. Since the P600 component of event related potentials has been hypothesized that represents aspects of second-pass parsing processes of information processing, and is related to WM, the present study focuses on P600 el...

journal_title：Neuroreport

authors： Papageorgiou C,Kontaxakis VP,Havaki-Kontaxaki BJ,Stamouli S,Vasios C,Asvestas P,Matsopoulos GK,Kontopantelis E,Rabavilas A,Uzunoglu N,Christodoulou GN

更新日期：2001-09-17 00:00:00

abstract：:Learning and memory are cognitive functions commonly impaired after surgery, especially in elderly patients. Our aim was to evaluate the effect of sevoflurane anaesthesia on episodic-like memory in young and aged wild-type mice and mice with altered nicotinic cholinergic neurotransmission (beta2KO). Mice learned objec...

journal_title：Neuroreport

authors： Wiklund A,Granon S,Faure P,Sundman E,Changeux JP,Eriksson LI

更新日期：2009-10-28 00:00:00