Mutation screening in exons 3 and 4 of alpha-synuclein in sporadic Parkinson's and sporadic and familial dementia with Lewy bodies cases.

abstract：:This study was performed to test the hypothesis that diminution in the preovulatory luteinizing hormone (LH) surge in middle-aged (MA) rats may be related to altered activity in nitric oxide (NO)ergic neurons. To begin to test the hypothesis, gene expression of hypothalamic NO synthase (NOS), the enzyme that catalyzes...

journal_title：Neuroreport

authors： Sahu A

更新日期：1998-12-21 00:00:00

abstract：:Proteins of the postsynaptic density are implicated in mechanisms of synaptic plasticity. We examined involvement of PSD95 and alphaCaMkII in learning-dependent plastic changes of representational maps in somatosensory cortex of mice. The barrel cortex of mice was examined following a 3 day long classical conditioning...

journal_title：Neuroreport

authors： Skibinska A,Lech M,Kossut M

更新日期：2001-09-17 00:00:00

abstract：:Auditory sensory memory is assumed to play an important role in cognitive development, but little is known about it in young children. The aim of this study was to estimate the duration of auditory sensory memory in 2-year-old children. We recorded the mismatch negativity in response to tone stimuli presented with dif...

journal_title：Neuroreport

authors： Glass E,Sachse S,von Suchodoletz W

更新日期：2008-03-26 00:00:00

abstract：:A double-stranded DNA end-binding factor with high levels of expression in brain and testis of adult mice was identified as the Ku protein, earlier described as an autoantigen in connective tissue diseases and found to be essential for recombination of the immunoglobulin genes and DNA repair. High Ku levels were found...

journal_title：Neuroreport

authors： Bakalkin G,Yakovleva T,Hurd YL,Nussenzweig A,Li GC,Terenius L

更新日期：1998-06-22 00:00:00

abstract：:Exposure of primary murine cortical neuron cultures to N-methyl-D-aspartate (NMDA) resulted in neuronal death as evidenced by release of lactate dehydrogenase (LDH) into the media. The addition of N-nitro-L-arginine (N-Arg) protected the neurons from death in a concentration-dependent manner when added after the NMDA,...

journal_title：Neuroreport

authors： Reif DW

更新日期：1993-05-01 00:00:00

abstract：:To clarify the time course of neural responses to faces with different emotional expressions, we used event-related potential (ERP) and reaction time measures. Faces expressing four different emotions (happy, neutral, fearful, disgusted) and houses were shown in both upright and inverted orientations while subjects pe...

journal_title：Neuroreport

authors： Ashley V,Vuilleumier P,Swick D

更新日期：2004-01-19 00:00:00

abstract：:We have found that regeneration of the rat sciatic nerve is stimulated if the rats are exposed to a 50 Hz sinusoidal magnetic field. In this study we investigated the effect of a Ca2+ antagonist, methoxyverapamil (D600) on this response. D600 was administered to the regenerating segment of the nerve via implanted osmo...

journal_title：Neuroreport

authors： Rusovan A,Kanje M

更新日期：1992-09-01 00:00:00

abstract：:The octave illusion is experienced when two simultaneous tones, separated by one octave and presented to the opposite ears, are continuously reversed between the two ears. Subjects consistently report a sequence of alternating single tones: the high tone in the right ear and the low in the left. We wished to determine...

journal_title：Neuroreport

authors： Ross J,Tervaniemi M,Näätänen R

更新日期：1996-12-20 00:00:00

abstract：:Latest reports suggest the involvement of insulin in modulating memory. A few published in-vitro studies favor the antidementia effect of insulin. Thus, the present study aimed to evaluate the prophylactic role of insulin and its combination with glucose and its possible mechanism(s) in an aluminum chloride (AlCl3)-in...

journal_title：Neuroreport

authors： Nampoothiri M,Kumar N,Venkata Ramalingayya G,Gopalan Kutty N,Krishnadas N,Mallikarjuna Rao C

更新日期：2017-06-14 00:00:00

abstract：:Using NADPH-diaphorase (NADPH-d) staining as a marker for the enzyme nitric oxide synthase (NOS) we investigated the possible sites of nitric oxide (NO) synthesis in the olfactory pathways of an insect brain. Staining of frozen sections revealed NADPH-d activity in neurones and in glial cells. A cluster of intensely s...

journal_title：Neuroreport

authors： Bicker G,Hähnlein I

更新日期：1995-01-26 00:00:00

abstract：:Using a guessing paradigm we measured visual sensitivity in the blind and normal half-fields of four cerebrally hemidecorticated patients. In the blind field, sensitivity was reduced by approximately 3 long units. Stimuli which produced significant detection also evoked conscious sensations of light and colour. Contro...

journal_title：Neuroreport

authors： Stoerig P,Faubert J,Ptito M,Diaconu V,Ptito A

更新日期：1996-08-12 00:00:00

abstract：:Cell death by apoptosis occurs in mature neurones of adult rat dentate gyrus following adrenalectomy. In these studies, apoptosis in the dentate gyrus was induced 3 days after adrenalectomy in male Fischer 344 rats ranging in age from 2-3 to 24-26 months. Glial fibrillary acidic protein and transforming growth factor-...

journal_title：Neuroreport

authors： Bye N,Nichols NR

更新日期：1998-04-20 00:00:00

abstract：:The death of spinal motoneurones after axotomy provides a useful model for studying novel factors which prevent motoneurone loss in vivo. Peripheral nerves of newborn rats were unilaterally transected and treated with either a vehicle solution or leukaemia inhibitory factor (LIF). Compared with the vehicle controls, t...

journal_title：Neuroreport

authors： Cheema SS,Richards LJ,Murphy M,Bartlett PF

更新日期：1994-04-14 00:00:00

abstract：:The mixed-action κ-opioid receptor (KOR) agonist, pentazocine, binds to both KOR and the µ-opioid receptor (MOR). Racemic (±)-pentazocine and (-)-pentazocine, each administered systemically, have been shown to produce antinociception in various animal models. In contrast, racemic (±)-pentazocine failed to produce anti...

journal_title：Neuroreport

authors： Robinson DL Jr,Nag S,Mokha SS

更新日期：2018-07-04 00:00:00

abstract：:In this study, we examine through electrophysiological measures three alternative mechanisms underlying musical chord priming: psychoacoustic distance, common parent-key, and distance along the circle of fifths. In contrast with previous behavioral studies, we present complex tones which do not blur the melodic compon...

journal_title：Neuroreport

authors： Granot RY,Hai A

更新日期：2009-06-17 00:00:00

abstract：OBJECTIVE:This study aimed to observe the effect of glutamine (Gln) on brain damage in septic rats and explore its possible mechanism. METHODS:Ninety-three Sprague-Dawley rats were randomly divided into five groups: sham operation group, sepsis group, Gln-treated group, quercetin/Gln-treated group, and alloxan/Gln-tre...

journal_title：Neuroreport

authors： Wang J,Lu X,Zheng K,Jing L

更新日期：2021-01-18 00:00:00

abstract：:Although a large amount of studies have manifested resting state electroencephalogram oscillatory abnormalities in schizophrenia and their first-degree relatives and in schizotype, the results are far from consistent and no research found any relationship between electroencephalograph (EEG) abnormalities and schizotyp...

journal_title：Neuroreport

authors： Chen C,Huang W,Chen X,Shi X,Zhu X,Ma W,Wang Y,Kang Q,Wang X,Guan M,Huang H,Wu S,Liu X

更新日期：2019-12-10 00:00:00

abstract：:Recent studies have yielded contradictory evidence on whether visual speech perception (watching articulatory gestures) can activate the human primary auditory cortex. To circumvent confounds due to inter-individual anatomical variation, we defined our subjects' Heschl's gyri and assessed blood oxygenation-dependent s...

journal_title：Neuroreport

authors： Pekkola J,Ojanen V,Autti T,Jääskeläinen IP,Möttönen R,Tarkiainen A,Sams M

更新日期：2005-02-08 00:00:00

abstract：:Newly hatched domestic chicks serve as an important model for experimental studies of neural and behavioral plasticity. Brain-derived neurotrophic factor (BDNF) has been shown to play a critical role in synaptic plasticity, including long-term potentiation, which underlies learning and memory in rodents. Here we show ...

journal_title：Neuroreport

authors： Yamaguchi S,Aoki N,Kobayashi D,Kitajima T,Iikubo E,Katagiri S,Matsushima T,Homma KJ

更新日期：2011-12-07 00:00:00

abstract：:To clarify possible interaction between the ventral hippocampal cannabinoid CB2 receptors and the cholinergic system in control of the memory process, the effects of cannabinoid and acetylcholine receptor agents on memory consolidation have been investigated in mice. Animals implanted with bilateral cannulas at the CA...

journal_title：Neuroreport

authors： Nasehi M,Forouzanmehr E,Khakpai F,Zarrindast MR

更新日期：2020-01-27 00:00:00

abstract：:Primate vision consists mostly of periods of stable fixation separated by rapid saccadic eye movements. Each saccade brings a new scene onto the retina, and each new scene results in a burst of activity in the neurons of visual cortex. It might be expected that the activity of these neurons should only represent what ...

journal_title：Neuroreport

authors： Gawne TJ,Woods JM

更新日期：2003-01-20 00:00:00

abstract：:In situ hybridization has demonstrated mRNA for olfactory receptors (OR) in the axon terminals of olfactory receptor neurons. Neurons that express the same OR appear to send their axons to two stereotyped glomeruli in the olfactory bulb (OB). Based on these observations, we tested the feasibility of using RT-PCR to is...

journal_title：Neuroreport

authors： Singer MS,Hughes TE,Shepherd GM,Greer CA

更新日期：1998-11-16 00:00:00

abstract：:Event-related potentials(ERPs) were measured while subjects were constructing mental images of a letter of the alphabet. Following presentation of an uppercase letter, subjects were asked to form a mental image of the same letter in lower case, and determine whether or not it had an ascending or descending stroke (asc...

journal_title：Neuroreport

authors： Yamamoto S,Mukai H

更新日期：1998-10-26 00:00:00

abstract：:5-[125I]iodo-3-(2(S)-azetidinylmethoxy)pyridine ([125I]5-I-A-85380) was evaluated in the mouse as a potential in vivo imaging ligand for central nicotinic acetylcholine receptors (nAChRs). After i.v. administration of [125I]5-I-A-85380, peak brain levels of radioactivity were measured within 1 h and declined slowly ov...

journal_title：Neuroreport

authors： Vaupel DB,Mukhin AG,Kimes AS,Horti AG,Koren AO,London ED

更新日期：1998-07-13 00:00:00

abstract：:Diffusion tensor imaging was used to measure regional differences in brain white matter microstructure (intravoxel coherence) and macrostructure (intervoxel coherence) and age-related differences between men and women. Neuropsychiatrically healthy men and women, spanning the adult age range, showed the same pattern of...

journal_title：Neuroreport

authors： Sullivan EV,Adalsteinsson E,Hedehus M,Ju C,Moseley M,Lim KO,Pfefferbaum A

更新日期：2001-01-22 00:00:00

abstract：:In a previous publication we showed that non-linear analysis can extract spatio-temporal changes of brain electrical activity prior to epileptic seizures. Here we describe a new method to analyze this long-term non-stationarity in the EEG by a measure of dynamical similarity between different parts of the time series....

journal_title：Neuroreport

authors： Le Van Quyen M,Martinerie J,Baulac M,Varela F

更新日期：1999-07-13 00:00:00

abstract：:We investigated the influence of gravity on the maturation of electrical properties of lumbar motoneurons and the development of their inputs from ventral descending pathways, which are important for the control of posture and locomotion. Using electrophysiological approaches in the in vitro brain stem-spinal cord pre...

journal_title：Neuroreport

authors： Brocard F,Clarac F,Vinay L

更新日期：2003-09-15 00:00:00

abstract：:When we perform a visually guided reaching action, the brain coordinates our hand and eye movements. Eye-hand coordination has been examined widely, but it remains unclear whether the hand and eye motor systems are coordinated during on-line visuomotor adjustments induced by a target jump during a reaching movement. A...

journal_title：Neuroreport

authors： Abekawa N,Inui T,Gomi H

更新日期：2014-05-07 00:00:00

abstract：:Regional cerebral blood flow (rCBF) was measured using PET and H2(15)O in Parkinson's disease (PD) patients with predominantly right-sided akinetic-rigid symptoms and in control subjects during the execution of an externally cued motor task either with the left or the right hand. During the execution of the task with ...

journal_title：Neuroreport

authors： Thobois S,Dominey P,Decety J,Pollak P,Gregoire MC,Broussolle E

更新日期：2000-03-20 00:00:00

abstract：:Prefrontal delay-period activity represents a neural mechanism for the active maintenance of information and needs to be controlled by some signal to appropriately operate working memory. To examine whether reward-delivery acts as this signal, the effects of delay-period activity in response to unexpected reward-deliv...

journal_title：Neuroreport

authors： Ichihara-Takeda S,Takeda K,Funahashi S

更新日期：2010-03-31 00:00:00