Abstract:
:We have found that regeneration of the rat sciatic nerve is stimulated if the rats are exposed to a 50 Hz sinusoidal magnetic field. In this study we investigated the effect of a Ca2+ antagonist, methoxyverapamil (D600) on this response. D600 was administered to the regenerating segment of the nerve via implanted osmotic minipumps. Magnetic field exposure increased regeneration distances in vehicle perfused nerves. This enhancement was blocked by perfusion with D600 at a concentration which alone failed to affect outgrowth of nerve fibres, lending support to the idea that Ca2+ fluxes could be involved in mediating the biological actions of magnetic fields.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Rusovan A,Kanje Mdoi
10.1097/00001756-199209000-00023subject
Has Abstractpub_date
1992-09-01 00:00:00pages
813-4issue
9eissn
0959-4965issn
1473-558Xjournal_volume
3pub_type
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