Abstract:
:To confirm neural plasticity of the mouse hippocampo-prefrontal cortex (PFC) pathway, paired-pulse facilitation (PPF) and long-term potentiation (LTP) induction were determined in the pathway. In addition, we tested whether the plasticity differs in projections of the pathway from the dorsal (upper) and ventral (lower) parts of the temporal hippocampus. The results showed PPF and LTP of this pathway, and these differed between the projections. The projection from the upper part showed stronger PPF and weaker LTP compared with that from the lower part. These results suggest that the mouse hippocampo-PFC pathway is involved in learning and memory, and contains projections related to different functions.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Izaki Y,Takita M,Nomura Mdoi
10.1097/00001756-200105080-00028subject
Has Abstractpub_date
2001-05-08 00:00:00pages
1191-3issue
6eissn
0959-4965issn
1473-558Xjournal_volume
12pub_type
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